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chinese Science Bulletin 2006年第14期51卷 1736-1740页

作者： SONG Zhiguang1,2 & WANG Cuiping1,3.. State Key Laboratory of Organic Geochemistry, Guangzhou institute of Geochemistry, chinese academy of sciences, Guangzhou 510640, china 2. Guangzhou Research Center of Gas Hydrate, chinese academy of sciences, Guangzhou 510640, china 3. Graduate School of chinese academy of sciences, Beijing 10003., china State Key Laboratory of Organic Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou China Guangzhou Research Center of Gas Hydrate Chinese Academy of Sciences Guangzhou China Graduate School of chinese academy of sciences Beijing China

A group of 2,6,10,15,19-pentamethyli- cosenes (PMIΔ) containing 1―5 unsaturated double bonds has been identified in the sea floor sediments from the Gulf of Mexico at the Green Canyon 23. *** PMIΔ compounds are distributed between nC22 and nC24 on the mass chromatogram of aliphatic fraction. Their δ 13. values are very much depleted in 13. and in the range of ?86.7‰ to ?115.5‰, whereas the δ 13. values of companion n-alkanes range from ?28.4‰ to ?3..6‰. These unsaturated PMIΔ com-pounds are typical biomarkers derived from the an-aerobic oxidation of methane mediated by meth-ane-oxidizing archaeal bacteria and indicative of the gas seeps or even the occurrence of gas hydrates in the deep sea sediments.

关键词：生物标志墨西哥湾沉积物 PMIA 天然气水化物

Study on growth and properties of novel γ-LiAlO_2 substrate

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Science china(Technological sciences) 2006年第2期49卷 188-193页

作者： ZOU Jun1,2, ZHOU Shengming1, XU Jun1 & ZHANG Rong3.1. Shanghai institute of Optics and Fine Mechanics, chinese academy of sciences, Shanghai 201800, china 2. Graduate School of chinese academy of sciences, Beijing 10003., china 3. Laboratory of Solid State Microstructures and Department of Physics, Nanjing University, Nanjing 210093. china Shanghai institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai China Graduate School of chinese academy of sciences Beijing China Laboratory of Solid State Microstructures and Department of Physics Nanjing University Nanjing China

Transparent γ-LiAlO2 single crystal has been grown by Temperature Gradient technique. The surface of the wafer annealed in O2-atmosphere at 1100°C for 70 h became opaque and Li-poor phase (LiAl5O8); while, that annealed in Li-rich atmosphere kept transparent and smooth. The full-width at half maximum value dropped to 3. arcsecs when the wafer was annealed in Li-rich atmosphere. That annealed in O2-atmosphere increased to 78 arcsec. Compared with absorption spectra, we can conclude that the 196 nm absorption peak was caused by Li vacancies and the 73. nm peak was caused by O vacancies.

关键词： γ-LiAlO2 crystal, scanning electron micrograph (SEM), absorption spectra.

Association between Alcohol, Smoking and HLA-DQA1*0201 Genotype in Psoriasis

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Acta Biochimica et Biophysica Sinica 2004年第9期36卷 597-602页

作者： Guang-Yong ZHENG1,2#, Sheng-Cai WEI3., Tie-Liu SHI1, and Yi-Xue LI1* 1Bioinformatics Center, Shanghai institutes for Biological sciences, chinese academy of sciences, Graduate School of the chinese academy of sciences, Shanghai 20003., china Research Center for Proteome Analysis, institute of Biochemistry and Cell Biology, Shanghai institutes for Biological sciences, chinese academy of sciences, Graduate School of the chinese academy of sciences, Shanghai 20003., china 3.uangzhou institute of Dermatology, Guangzhou 510095, china Bioinformatics Center Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of SciencesShanghai 200031 China Research Center for Proteome Analysis Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of SciencesShanghai 200031 China Guangzhou institute of DermatologyGuangzhou 510095 China

Psoriasis is a chronic skin disease triggered by genetic, environment or other risk factors such as infection, drugs, stress, moisture, alcohol, and smoking. A major psoriasis susceptibility locus at 6p21.3. has been identified. Further studies found that HLA-DQA1*0201 allele was associated with psoriasis. However, there were few data exploring an association between the environmental factors and susceptibility genes. In this study, the samples of 189 patients with psoriasis and 3.3.healthy controls were collected with their consent and were carried on analysis through polymerase chain reaction sequence-specific primer (PCR- SSP) method. The proportion of male psoriasis patients engaging in the smoking and alcohol was much higher than that of the control group (P6.91, P<1.0×10–4).

关键词： psoriasis HLA-DQA1*0201 allele smoking alcohol association

BRST quantization and canonical Ward identity of the supersymmetric electromagnetic interaction system

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Science china(Physics,Mechanics & Astronomy) 2007年第3期50卷 339-347页

作者： HUANG YongChang1,3.4, JIANG YunGuo1 & LI XinGuo2,3.1 institute of Theoretical Physics, College of Applied sciences, Beijing University of Technology, Beijing 100022, china 2 institute of Modern Physics, chinese academy of sciences, lanzhou 73.000, china 3.Center of Theoretical Nuclear Physics, National Laboratory of Heavy Ion Collisions, chinese academy of sciences, lanzhou 73.000, china 4 china Center of Advanced Science and Technology (World Laboratory), Beijing 100080, china institute of Theoretical Physics College of Applied Sciences Beijing University of Technology Beijing China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Collisions Chinese Academy of Sciences Lanzhou China china Center of Advanced Science and Technology (World Laboratory) Beijing China institute of Modern Physics Chinese Academy of Sciences Lanzhou China

According to the method of path integral quantization for the canonical constrained system in Becchi-Rouet-Stora-Tyutin scheme, the supersymmetric electromagnetic interaction system was quantized. Both the Hamiltonian of the supersymmetric electromagnetic interaction system in phase space and the quantization procedure were simplified. The BRST generator was constructed, and the BRST transforma- tions of supersymmetric fields were gotten; the effective action was calculated, and the generating functional for the Green function was achieved; also, the gauge generator was constructed, and the gauge transformation of the system was ob- tained. Finally, the Ward-Takahashi identities based on the canonical Noether theorem were calculated, and two relations between proper vertices and propaga- tors were obtained.

关键词： supersymmetric electromagnetic interaction BRST quantization Ward identity

Expression of Monomeric Insulin Precursor in Pichia pastoris and Its Conversion into Monomeric B27 Lys Destripeptide Insulin by Tryptic Hydrolysis

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Acta Biochimica et Biophysica Sinica 2005年第4期37卷 234-240页

作者： Jin-Guo DING~(1,3. Jian FEI~2 Da-Fu CUI~1 You-Shang ZHANG~1 ~1institute of Biochemistry and Cell Biology,and ~2Model Organism Research Center,Shanghai institutes for Biologicol sciences,{3.,Shanghai 20003.,china ~3.raduate School of the{3.,Shanghai 20003.,china institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China Graduate School of the chinese academy of sciences Shanghai 20003. China Model Organism Research Center Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China

Monomeric B27 Lys destripeptide insulin (B27 Lys DTrI) was designed and produced from itsprecursor expressed in Pichia pastoris through tryptic hydrolysis instead of the less efficient *** monomeric B27 Lys DTrI precursor (MIP) was purified from a cultured medium *** by a combination of hydrophobic,size-exclusion,and ion-exchange *** purifiedMIP was converted,by tryptic hydrolysis,to B27 Lys DTrI,which was then purified by ion-exchangechromatography to homogeneity as assessed by native gel electrophoresis,HPLC,amino acid composition,and electrospray mass-spectrometric analysis.B27 Lys DTrI exhibited superior monomeric properties insize-exclusion *** yield of MIP was 200 mg per liter of culture,and the overall yield ofpurified B27 Lys DTrI from the crude MIP was 70%.The in vivo biological activity of B27 Lys DTrI asdetermined by the mouse convulsion assay was 21 U/mg,identical to that obtained by semisynthesis.

关键词： monomeric B27 Lys destripeptide insulin tryptic hydrolysis Pichia pastoris

Distribution characteristics of magnetic susceptibility of the surface sediments in the southern Yellow Sea

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chinese Science Bulletin 2003年第B6期48卷 37-41页

作者： GE Shulan~(1,2,3., SHI Xuefa~1 & HAN Yibing~1 1. Key Laboratory of Marine Sedimentology and Environmental geology, First institute of Oceanography, State Oceanic Administration. Qingdao 266061. china 2. institute of geology and Geophysics, chinese academy of sciences, Beijing 100029. china 3. Graduate School. chinese academy of sciences, Beijing 10003.. china Key Laboratory of Marine Sedimentology and Environmental geology First Institute of Oceanography State Oceanic Administration Qingdao China institute of geology and Geophysics Chinese Academy of Sciences Beijing China Graduate School Chinese Academy of Sciences Beijing China

The characteristic distributions of magnetic susceptibility (MS) are analyzed on the basis of susceptibility of 172 surface sediment samples in the southern Yellow Sea (SYS). The preliminary results are as follows: first, the distributions clearly correspond to different modern sediment assemblages in the continental sea, which indicates different sediment origins. With the 3. μCGS isoline being taken as demarcation line, the study area can then be divided into section H (high MS value area) and section L (low MS value area). Section H is mainly adjacent to land with two main sources of the Changjiang River and the Huanghe *** L is mainly an eddy sediment area, where Yellow Sea Cold Water is entrenched all the year round. The distribution pattern of MS could tell apart strong or weak hydrodynamic conditions and has a close relation to the circulation system in this area. At the areas of the SYS Circumfluent and northern East china Sea (NECS) Circumfluent (weak hydrodynamic), the MS has low values, while in the areas of Coastal Current (strong hydrodynamic), the values are *** the same time, the oxidizing areas tend to take on higher MS, while the reducing areas have lower one. It seems safe to say that the MS in the continental sea reflects more of the sediment origin and sedimentary environment, which is different from that of loess, lake and surface soil as a climate proxy.

关键词：中国黄海表面沉积物磁化率等值线长江黄河旋涡沉积区循环系统

Comparative Analysis of Two-component Signal Transduction System in Two Streptomycete Genomes

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Acta Biochimica et Biophysica Sinica 2007年第5期39卷 317-325页

作者： WU WEI~(1,3.), Weihua WANG~(2#), Zhiwei CAO~(3.), Hong YU~3. Xiaojing WANG~1, Jing ZHAO~3. Hao TAN~3. Hao XU~3. Weihong JIANG~(2*), and Yixue LI~(1,3.) 1 Bioinformation Center, Key Lab of Systems Biology, Shanghai institutes for Biological sciences, chinese academy of sciences, Graduate School of the chinese academy of sciences, Shanghai 20003., china 2 Laboratory of Molecular Microbiology, institute of Plant Physiology and Ecology, Shanghai institutes for Biological sciences, chinese academy of sciences, Graduate School of the chinese academy of sciences, Shanghai 20003., china 3.Shanghai Center for Bioinformation Technology, Shanghai 20023., china Bioinformation Center Key Lab of Systems Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of SciencesShanghai 200031 China Shanghai Center for Bioinformation TechnologyShanghai 20023. China Laboratory of Molecular Microbiology Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of SciencesShanghai 200032 China

Species of the genus Streptomyces are major bacteria responsible for producing most natural antibiotics. Streptomyces coelicolor A3.2) and Streptomyces avermitilis were sequenced in 2002 and 2003. respectively. Two-component signal transduction systems (TCSs), consisting of a histidine sensor kinase (SK) and a cognate response regulator (RR), form the most common mechanism of transmembrane signal transduction in prokaryotes. TCSs in S. coelicolor A3.2) have been analyzed in detail. Here, we identify and classify the SK and RR of S. avermitilis and compare the TCSs with those of S. coelicolor A3.2) by computational approaches. Phylogenetic analysis of the cognate SK-RR pairs of the two species indicated that the cognate SK-RR pairs fall into four classes according to the distribution of their orthologs in other organisms. In addition to the cognate SK-RR pairs, some potential partners of non-cognate SK-RR were found, including those of unpaired SK and orphan RR and the cross-talk between different components in either strain. Our study provides new clues for further exploration of the molecular regulation mechanism of streptomycetes with industrial importance.

关键词： Streptomyces two-component system cross-talk phylogenetic analysis

An improved method for evaluating the seasonal variability of total suspended sediment flux field in the Yellow and East china Seas

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International Journal of Sediment Research 2011年第1期26卷 1-14页

作者： PANG Chongguang~1,YU Wei~2,YANG Yang~3.and HAN Danxiu~4 institute of Oceanology,chinese academy of{3.,Qingdao 266071,china, 2 institute of Oceanology,chinese academy of{3.,Qingdao 266071,china,Graduate School of chinese academy of sciences,Beijing 10003.,china 3.institute of Oceanology,chinese academy of{3.,Qingdao 266071,china,Graduate School of chinese academy of sciences,Beijing 10003.,china 4 china University of Petroleum,Beijing 102249,china Doctor Researcher Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China Graduate School of Chinese Academy of Sciences Beijing 100039 China china University of Petroleum Beijing 102249 China

The suspended sediment flux field in the Yellow and East china Seas(YECS) displays its seasonal variability.A new method is introduced in this paper to obtain the flux field via retrieval of ocean color remote sensing data,statistical analysis of historical suspended sediment concentration data,and numerical simulation of three-dimensional(3.) flow *** components of the sediment flux field include(i) surface suspended sediment concentration inverted from ocean color remote sensing data;(ii) vertical distribution of suspended sediment concentration obtained by statistical analysis of historical observation data;and(iii) 3. flow field modeled by a numerical *** the improved method,the 3. suspended sediment flux field in the YECS has been *** comparison with the suspended sediment flux field solely based on the numerical simulation of a suspended sediment transport model,the suspended sediment flux field obtained by the improved method is found to be more *** 3. suspended sediment flux field from ocean colour remote sensing and in situ observation are more closer to the ***,by quantitatively analyzing the newly obtained suspended sediment flux field,the quantity of sediment erosion and deposition within the different regions can be *** sediment exchange between the Yellow Sea and the East china Sea can be *** mechanism of suspended sediment transport in the YECS can be better *** particular,it is suggested that the long-term transport of suspended sediment is controlled mainly by the circulation pattern,especially the current in winter.

关键词： Suspended sediment flux field Seasonal variability Yellow and East china Seas Regression equation Numerical simulation

Review on the study of entanglement in quantum computation speedup

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chinese Science Bulletin 2007年第16期52卷 2161-2166页

作者： DING ShengChao1,3.& JIN Zhi1,2,1 institute of Computing Technology,chinese academy of{3.,Beijing 100080,china 2 academy of Mathematics and Systems Science,chinese academy of{3.,Beijing 100080,china 3.Graduate University of chinese academy of sciences,Beijing 100080,china institute of Computing Technology Chinese Academy of Sciences Beijing China Graduate University of chinese academy of sciences Beijing China academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing China

The role the quantum entanglement plays in quantum computation speedup has been widely disputed. Some believe that quantum computation's speedup over classical computation is impossible if entan-glement is absent,while others claim that the presence of entanglement is not a necessary condition for some quantum algorithms. This paper discusses this problem systematically. Simulating quantum computation with classical resources is analyzed and entanglement in known algorithms is reviewed. It is concluded that the presence of entanglement is a necessary but not sufficient condition in the pure state or pseudo-pure state quantum computation speedup. The case with the mixed state remains open. Further work on quantum computation will benefit from the presented results.

关键词：量子论量子纠缠量子计算加速模拟

U-Pb dating of zircon from the bed parallel anatectic granitic intrusion in the Baoban group in Hainan Island and the tectonic implication

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Science china Earth sciences 2005年第12期48卷 2092-2103页

作者： DING Shijiang1, HU Jianmin2, SONG Biao3.4, CHEN Mulun1, XIE Shengzhou1 & FAN Yuan1 1. Geological Surveying institute of Hainan, Haikou 570206, china 2. institute of Geomechanics,{3. academy of Geological sciences, Beijing 100081, china 3. Beijing Center of SHRIMP, Beijing 10003., china 4. institute of geology,{3. academy of Geological sciences, Beijing 10003., china Geological Surveying institute of Hainan Haikou China institute of Geomechanics Chinese Academy of Geological Sciences Beijing China Beijing Center of SHRIMP Beijing China institute of geology Chinese Academy of Geological Sciences Beijing China

The petrological and geochemical features of the bed parallel granitic intrusion in the Pre-Cambrian Baoban group in Hainan Island attest to the anatexis origin of the granites. U-Pb dating analyses of zircons from the anatectic granite and the biotite two-feldspar gneiss in the Baoban group, using SHRIMP II in the Beijing Ion-probe Center, acquire 206Pb/23.U ages of 3.8±3.5 Ma (of granite, 95% confidence level, MSDW=1.23. and 3.2.9±6.1 Ma (of gneiss, 95% confidence level, MSDW = 2.04) respectively. The two late Devonian ages indicate consistently a tectonic- thermal event experienced in Hainan Island, and are the first discovered record of the Devonian geological process in the district. This event possibly resulted from the deep ther-mal-dynamic process when the Gondwana continent began to break up in the Devonian period.

关键词： Hainan Island, Devonian period, anatectic granite, zircon SHRIMP U-Pb dating.