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Neuroprotective effect of nicotine on neurodegenerative diseases

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Neuroprotective effect of nicotine on neurodegenerative dise...

第一届全国脑与认知科学学术研讨会

作者： Baolu Zhao State Key Laboratory of Brain and Cognitive Science institute of Biophysics chinese {3. of sciences beijing china 100101

＜正＞Epidemiology shows that smokers have less risk to catch degenerative diseases such as Alzheimer’s disease （AD） and Parkinson’s disease （PD） that are both correlated with enhanced oxidative stress. The main component in smoke is nicotine. We have studied its antioxidant properties and effect on AD and PD in cell and animal systems. The scavenging effect of nicotine on free radicals was investigated by electron spin resonance techniques. It was found that the scavenging effect of nicotine on hydroxyl radicals and superoxide free radicals was

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IR STUDIES ON SURFACE CHEMISTRY OF RHODIUM IN HYDROFORMYLATION CATALYSTS

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Journal of energy Chemistry 1996年第3期 237-249页

作者： HUANG Lin XU Yi-De (State Key Laboratory of CatalysisDalian institute of Chemical physics, The chinese {3. of sciencesDalian, Liaoning 116023.

The interactions of supported Rh0 and cobalt- and iron- promotedRh0 with the SiO2 surfacc havc been investigated by IR spectroscopy. Thehighly dispersed rhodium particles dcrived by H2 decarbonylation ofRh6(CO)16/SiO2 are oxidized to isolated Rh+ by surface OH via heating at623.K under vacuum, which adsorbs CO to form R-h'(CO)2. The interactionsof added cobalt and iron with Rh0 suppress the oxidation of Rh0. Theresults show that the cobalt and iron promoters play an electron-donatingrole, thus increasing thc electron density of rhodium *** electroniceffect can be correlated with the observed promotion of catalytic ethylenehydroformylation. In situ IR observations indicate that supported Rh0 onRh/SiO2 is an activc site for hydrofonnylation.

关键词： SiO2-supported Rh Rh~0 oxidation promotion of cobalt and iron hydroformylation

Entropy Squeezing in Coupled Field-Superconducting Charge Qubit with Intrinsic Decoherence

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Communications in Theoretical physics 2007年第7期48卷 63-66页

作者： YAN Xue-Qun SHAO Bin ZOU Jian Department of Physic,School of Science,beijing institute of Technology,beijing 100081,{3. Department of Physic School of Science Beijing Institute of Technology

We investigate the entropy squeezing in the system of a superconducting charge qubit coupled to a singlemode *** find an exact solution of the Milburn equation for the system and discuss the influence of intrinsicdecoherence on entropy *** a comparison,we also consider the variance *** results show that inthe absence of the intrinsic decoherence both entropy and variance squeezings have the same periodic properties of time,and occur at the same range of ***,when the intrinsic decoherence is considered,we find that as the timegoing on the entropy squeezing disappears fast than the variance squeezing,there exists a range of time where entropysqueezing can occur but variance squeezing cannot.

关键词： entropy squeezing intrinsic decoherence superconducting charge qubit

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Microbial degradation of chlorinated nitroaromatics and bioremediation of polluted environments

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Microbial degradation of chlorinated nitroaromatics and bior...

2008年中国微生物学会学术年会

作者： Shuang-Jiang Liu institute of Microbiology,chinese academy of Science,{3.,china

Chlorinated nitroaromatic compounds such as chloronitrobenzenes are massively produced and are widely used as intermediates for chemical syntheses of drugs, herbicides,and dyes,*** strain CNB-1 is a new bacterial isolate that grows on 4-chloronitrobenzene(4-CNB) and nitrobenzene as sole carbon and nitrogen *** this report,the genetics and physiology of chloronitrobenzene degradation,

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The Coupling Waves of Multicore-Fiber

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光学学报 2003年第S1期23卷 106-107页

作者： Lingfeng Kong Qihong Lou JunZhou Zhijiang Wang Shanghai institute of Optics and Fine Mechanics, CAS, P. R. china, Tel: 86-21-59910484, Fax: 86-21-59916703.E-mail: lf_kong@*** Graduate School, The chinese {3. of sciences, beijing, 10003., china Shanghai institute of Optics and Fine Mechanics CAS P. R. China Graduate School The Chinese Academy of Sciences Beijing 100039 China Shanghai institute of Optics and Fine Mechanics CAS P. R. China

Multicore-fiber as gain medium for fiber laser is introduced. The cores are coupled via evanescent waves. Analysis of the coupling waves is agree with the numerical simulations and experimental results.

关键词： of The Coupling Waves of Multicore-Fiber mode that in be

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Size-dependent translocation pattern,chemical and biological transformation of ferric oxide nanoparticles in the central nervous system

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Size-dependent translocation pattern,chemical and biological...

中国毒理学会第三届中青年学者科技论坛暨2011年全国前列腺药理毒理学研讨会

作者： Bing Wang,~+ Ming Li,~+ Yun Wang,~+ Meng Wang,~+ Hong Ouyang,~+ Jing Zhang,Dong L. Chen,Zhi F.Chai,~+ Wei Y.Feng,~(+*)and Yu L.Zhao~(+*) + Laboratory for Bio-Medical Effects of Nanomaterials and Nanosafety and Key Laboratory of Nuclear Analytical Techniques,institute of high energy {3.,chinese academy of sciences,beijing 100049,china beijing Synchrotron Radiation Facility,institute of high energy {3.,beijing 100049, china

The toxic effects or biomedical functions of nanoparticles largely depend on their translocation ***,because of a large number of variable parameters of nanoparticles,experimental measurements of each type of nanoparticles in vivo become a huge work and almost ***,establishing theoretical models for rapid analyses will be beneficial to both safety estimation and application of *** the present study,the size-dependent translocation mode and biological fate of intranasally instilled FeO nanoparticles(40 nm and 280 nm)in CNS were *** nanoparticle translocation in different parts of brain at 4h,12h,24h,3.,7d,and 3.d were quantified using ICP-MS technique.A biexponential model(correlation coefficient r=0.98～0.99)was satisfactory to describe the particokinetic translocation behavior of FeO nanoparticles in *** found a size-dependent translocation pattern and a size-sensitive time-window(4-72 h)of the nanoparticles in the brain,which are most significant in toxic concerns of nanoparticles in the *** synchrotron-based techniques such as microbeam X ray fluorescence(SR-μXRF) and near-edge X-ray absorption spectroscopy(XANES)were then used to map the spatial microdistribution and to identify the chemical forms of the nanoparticles in brain,respectively. The SR-μXRF images showed the 40 nm-FeO particles more widely distributed in brain regions than the large FeO particle *** XANES results indicate that the presence of chemical speciation of the FeO nanoparticle(～15%)and protein-complex like apotransferrin-FeO(～16%)in brain,implying that self-coating of FeO nanoparticles occurred with transferrin in *** but not the least,all the findings suggest size-sensitive manners of nanoparticles in brain,the smaller one possesses evident detention properties in the CNS *** larger one.

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Life history characteristics and population prediction of the alien Pelteobagrus fuividraco (Richardson,1846) in Lake Fuxian,china

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Life history characteristics and population prediction of th...

中国海洋湖沼动物学会鱼类学分会第七届会员代表大会暨朱元鼎教授诞辰110周年庆学术研讨会

作者： X.Li~(1,2) Y.Chen~1 1.institute of Hydrobiology,chinese academy of {3.,Wuhan,china 2.Graduate School of chinese academy of {3.,beijing,china

Pelteobagrus fulvidraco were introduced unintentionally to the Lake Fuxian as alien specie about the 1990s,and presented a relative stable output in the survey catches since *** age of specimens selected was between 0-5 years for females and 0-7 years for males according to reading vertebrae. The growth parameters of the von Bertalanffy equation were L=294.68 mm,k=0.2476 year,t= -0.0298 year,W=209.93.g in male and L=257.13.mm,k=0.2219 year,t=-0.3.29 year,W= 184.45 g in *** differences were found in the sex ratio in favor of male(1:1.64).The estimated TL is in 128.14 mm for female and 13..99 mm for male,*** Mean absolute fecundity(F)was 23.4 oocytes,ranging from 43. to *** reproductive activity extended from mid-May to end of August,with peaks in *** type of reproduction was batch *** instantaneous coefficients of total mortality(Z)and natural mortality(M)were assessed 0.99 yearand 0.43.year for male,1.22 yea and 0.40 year for *** are sought by comparing traits from that of source *** study documents the plasticity of slow growth, large adult body size,descending fecundity and delayed maturity to cope with environmental variability,and population dimension will maintain at a high level in successive years in Lake Fuxian.

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序列呈现的刺激可以被并行的加工:来自注意瞬脱研究的证据(英文)

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心理学报 2004年第4期36卷 417-425页

作者：张侃杜峰中国科学院心理研究所中国科学院研究生院北京100039

采用RSVP范式验证了两个序列呈现的刺激可以被并行加工的假设。实验一发现 :在两个目标刺激(Target和Probe,以下简称T和P)间无干扰刺激时 ,T的反应时随着T、P之间的间隔显著减小 ,其模式符合并行加工模型的预测。而实验二发现 :当T和P... 详细信息

采用RSVP范式验证了两个序列呈现的刺激可以被并行加工的假设。实验一发现 :在两个目标刺激(Target和Probe,以下简称T和P)间无干扰刺激时 ,T的反应时随着T、P之间的间隔显著减小 ,其模式符合并行加工模型的预测。而实验二发现 :当T和P之间有干扰刺激 (即T后呈现后续掩蔽 )时 ,T的反应时并不随着T、P的间隔而减小 ,其模式符合序列加工模型的预测。由此可推论 ,只要两个序列呈现的刺激之间没有干扰刺激 ,可以对他们进行并行的注意加工。

关键词：并行加工模型序列加工模型注意瞬脱

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General Latent Structure Models and Statistical Validation of Osteoporosis syndromes feature of community women

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General Latent Structure Models and Statistical Validation o...

2011 13.h IEEE Joint International Computer Science and Information Technology Conference(JICSIT 2011)

作者： Wei Yang School of Statistics RenMin University of china beijing, china Yanming Xie {3. of Basic Research in Clinical Medicine china academy of chinese Medical sciences beijing, china Danhui Yi School of Statistics RenMin University of china beijing, china Feng Tian {3. of Basic Research in Clinical Medicine china academy of chinese Medical sciences beijing, china

Objective: Defining basic syndromes feature of Osteoporosis (OP) is an important avenue for prevention and treatment of TCM (traditional chinese medicine) for OP patients. We use machine learning techniques to establish objective and quantitative diagnosis standards for syndrome differentiation of OP and to give statistical validation of OP syndromes feature of community women. Method: One crucial step of TCM diagnosis is syndrome differentiation which is simply a classifier that classifies patients into different classes based on their symptoms. Previous clustering methods are unable to cope with the complexity of TCM. We therefore present a new multidimensional clustering method in the form of General latent structure (GLS) models, which is a useful tool of latent structure analysis. In this paper, the notion of GLS model is provided. We use an efficient learning algorithm to achieve an optimal GLS model from the OP real data set. Further, we use GLS model to analyze and present a case study of TCM syndrome differentiation for OP from qualitative and quantitative contents. Results: Our analysis has found natural clusters that correspond well to TCM basic syndrome types of OP population. The GLS model reflects much better model quality, provides statistical validation for TCM syndrome types of OP patients of community women and suggests the possibility of establishing objective and quantitative diagnosis standards for syndrome differentiation on OP.

关键词： Latent structure analysis General latent structure model Bayesian networks syndrom osteoporosis Traditional chinese Medicine