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Relationship between Multi-Phase Formation and Molecular Structure for Liquid Crystal System

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Journal of wuhan university of technology(Materials Science) 2005年第3期20卷 11-13页

作者：李振新 Biomedical Materials and Engineering Centre Wuhan University of Technology Department of Life Science and technology Xinxiang Medicine CollegeXinxiang 453003 China

4 mechanical model of liquid crystals （ LCs ） was used to explain the phase formation and thermal properties . The LC plusses in the model are micro- machine systems consisting of an ensemble of molecular rotors, and some dynamie parameters in a semi-experiment molecular orbit method. A novel explanation on the multi-phase formation of LC system is obtained. It is found that the value of the critical rotational velueity is a key parameter for the characterization of each homologous series. The dipole moment of the molecules was also discussed.

关键词： liquid crystal phase dynamic molecular structure

Inhibition of ethanol-induced toxicity by tanshinone ⅡA in PC12 cells

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Acta Pharmacologica Sinica 2006年第6期27卷 659-664页

作者： Xian-fang MENG~2 Xiao-jing ZOU~3.Bin PENG~2 Jing SHI~2 Xin-min GUAN~2 Chun ZHANG~(4,5)2 Department of Neurobiology,Tongji Medical college,Huazhong university of Science and technology,{3. 43.03.,china 3.Department of Anesthesiology,4 Department of Nephrology,Union Hospital,Tongji Medical college,Huazhong university of Science and technology,{3. 43.022.china Department of Neurobiology Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Anesthesiology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Nephrology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China

Aim:To observe the effects of tanshinone IIA(Tan IIA)on the neurotoxicityinduced by ethanol in PC 12 cells and to explore its protective ***:PC 12cell survival was measured by MTT *** formation of reactive oxygenspecies(ROS)and lactate dehydrogenase(LDH)release were detected by 2′,7′-dichlorofluorescin(DCF)fluorescence and calorimetric method,*** of cell apoptosis was monitored by flow *** expression ofp53.was detected by immuno-fluorescence and flow ***:Ethanolsignificantly impaired the survival of PC12 cells as demonstrated by MTT *** also induced significant ROS formation and increased LDH ***-incubation with Tan IIA in the culture medium significantly reversed these *** caused cell apoptosis and the upregulation of p53.*** anti-apoptosis effects of Tan IIA on ethanol-induced toxicity were accompanied by thedownregulation of pro-apoptotic p53.protein ***:Tan IIAcan protect neurons from apoptosis and might serve as a potential therapeuticdrug for neurological disorders induced by ethanol.

关键词： apoptosis ethanol PC12 cells p53 tanshinone ⅡA

Applications of semigroups of operators to non-elliptic differential operators

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Chinese Science Bulletin 2000年第8期45卷 673-682页

作者： ZHENG QuanDepartment of Mathematics, Huazhong university of Science and technology, wuhan 43.074, {3. Department of Mathematics Huazhong University of Science and Technology Wuhan China

This paper treats systematically the semigroup method of non-elliptic differential operators, which was developed in the last ten years. In particular, a review of the applications of regularized semigroups to non-elliptic differential operators with constant coefficients or time-dependent coefficients, parabolic systems, correct systems, abstract differential operators and pseudodifferential operators is given here. It is also shown that the regularized semigroup is an appropriate tool for non-elliptic differential operators and is far superior to the integrated semigroup approach.

关键词： differential operator regularized semigroup integrated semigroup initial value problem Fourier multiplier.

Characteristics of fMRI BOLD signal and its neurophysiological mechanism

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Progress in Natural Science:Materials International 2007年第6期17卷 630-638页

作者： Zhao Xiaohu1,2, Wu Yigen3.and Guo Shengli3.1. college of Life Sciences, Zhejiang university, Hangzhou 3.0058, china 2. Imaging Department of Tongji Hospital of Tongji university, Shanghai 200065, china 3. college of Mathematics and physics, Nanjing university of Information Science and technology, Nanjing 210044, china) college of Life Sciences Zhejiang University Hangzhou 310058 China Imaging Department Tongji Hospital Tongji University Shanghai 200065 China college of Mathematics and physics Nanjing University of Information Science and Technology Nanjing 210044 China

The functional magnetic resonance imaging (fMRI) based on blood oxygen level dependent (BOLD) contrast has emerged as one of the most potent noninvasive tools for mapping brain function and has been widely used to explore physiological, pathological changes and mental activity in the brain. Exploring the nature and property of BOLD signal has recently attracted more attentions. Despite that great progress has been made in investigation of the characteristics and neurophysiological basis, the exact nature of BOLD signal remains unclear. In this paper we discuss the characteristics of BOLD signals, the nonlinear BOLD response to external stimuli and the relation between BOLD signals and neural electrophysiological recordings. Furthermore, we develop our new opinions regarding nonlinear BOLD response and make some perspectives on future study.

关键词： functional magnetic resonance imaging blood oxygen level dependent nonlinear response neural electrophysiological activity.

Research on Ultrafine Tungsten Carbide-Cobalt(WC-Co) Cemented Carbide Rods of Miniature Drills for Highly Integrated Printed Circuit Board(PCB)

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Journal of Materials Science & technology 2005年第3期21卷 353-356页

作者： Xiaoliang SHI, Gangqin SHAO, Xinglong DUAN and Runzhang YUAN State Key Laboratory of Advanced technology for Materials Synthesis & Processing, wuhan university of technology, {3. 43.070, china Lab. of Advanced technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China

Nanocrystalline tungsten carbide-cobalt (WC-Co) composite powders produced through spray thermal decomposition-continuous reduction and carburization technology were used to prepare φ3.25 mm×3. mm ultrafine tungsten carbide-cobalt (WC-Co) cemented carbide rods through vacuum sintering plus sinterhip technology. The microstructure, Vickers hardness, density and Rockwell A hardness (HRA), transverse rupture strength (TRS), saturated magnetization and coercivity force were tested. The results show that the average grain size of the sintering body prepared through vacuum sintering plus sinterhip technology was 43. nm; transverse rupture strength (TRS) was 3.50 MPa; Vickers hardness was 1890 and Rockwell A hardness of sintering body was 93. High strength and high hardness ultrafine WC-Co cemented carbide rods used to manufacture printed circuit board (PCB) drills were obtained.

关键词： Nanocrystalline Composite powder Cemented carbide Rods

The Research of Scattering Cross-Section and Energy-Extraction in FEL

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Chinese Journal of Lasers 1995年第1期B4卷 25-29页

作者： ZHU Jiaqing (Department of physics,Central china Normal university,{3.,43.070,china) Central china Normal Univ Wuhan China

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关键词： free-electron laser scattering cross-section

PEGylated PLGA Nanoparticles as Tumor Ecrosis Factor-α Receptor Blocking Peptide Carriers:Preparation,Characterization and Release in vitro

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Journal of wuhan university of technology(Materials Science) 2007年第1期22卷 112-116页

作者：刘卫杨祥良 college of Life Science and technology Huazhong University of Science and Technology

To assess the merits of PEGylated poly （lactic-co-glycolic acid）（PEG-PLGA） nanoparticles as drug carriers for tumor necrosis factor-α receptor blocking peptide （TNFR-BP）, PEG-PLGA copolymer, which could be used to prepare the stealth nanoparticles, was synthesized with methoxypolyethyleneglycol, DL-lactide and glycolide. The structure of PEG-PLGA was confirmed with ^1H-NMR and FT-IR spectroscopy, and the molecular weight （MW） was determined by gel permeation chromatography. Fluorescent FITC-TNFR- BP was chosen as model protein and encapsulated within PEG-PLGA nanoparticles using the double emulsion method. Atomic force microscopy and photon correlation spectroscopy were employed to characterize the stealth nanoparticles fabricated for morphology, size with polydispersity index and zeta potential. Encapsulation efficiency （EE） and the release of FITC-TNFR-BP in nanopartieles in vitro were measured by the fluorescence measurement. The stealth nanoparticles were found to have the mean diameter less than 270 nm and zeta potential less than -20 mV. In all nanoparticle formulations, more than 45% of EE were obtained. FITC-TNFR-BP release from the PEG-PLGA nanoparticles exhibited a biphasic pattern, initial burst release and consequently sustained release. The experimental results show that PEG-PLGA nanoparticles possess the potential to develop as drug carriers for controlled release applications of TNFR-BP.

关键词： tumor necrosis factor-α receptor blocking peptide PEG-PLGA stealth nanoparticles ring-opening polymerization controlled and sustained drug release

SEPARATION PROPERTY OF POSITIVE RADIAL SOLUTIONS FOR A GENERAL SEMILINEAR ELLIPTIC EQUATION

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Acta Mathematica Scientia 2011年第1期31卷 181-193页

作者：杨芬张丹丹 college of Science Wuhan University of Science and Technology Department of Mathematics Xiangfan University

The asymptotic behavior at infinity and an estimate of positive radial solutions of the equation △u ＋ sum from i=1 to k cirli upi = 0, x ∈ Rn,（0.1）are obtained and the structure of separation property of positive... 详细信息

关键词： Asymptotic behavior separation property semilinear elliptic equation

Neural Nets:Another Paradigm for Decision Support

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Journal of Systems Engineering and Electronics 1995年第2期6卷 2-8页

作者： Feng Shan (Dept. of ACE, Huazhong university of Science and technology, wuhan 43.074, {3.) Dept. of ACE Huazhong University of Science and Technology Wuhan 430074 China

The paper presents an important aspect of Neural Nets application, i. e., their usefulness for decision support. The essential feature of the neural net approach to decision making is that it is a black-box approach, which means one does not try to model the underlying processes, but only looks for a tuning of the parameters of the neural net such that the black-box mimics the sensible behavior. Through the existing widespread applications in industry, business and science, the paper emphasizes their common property as a paradigm for decision support.

关键词： Neural network Neural-net controller Decision support Industrial applications.