检索结果-南通市图书馆

Effects of r.d p.lm Oil on Ser.m Lip.ds and p.asma Car.tenoids Level in chinese Male Adults

Biomedical and Envir.nmental Sciences 2003年第4期16卷 348-354页

作者： JIAn ZHAnG , CHUn-r.nG WAnG, An-nA XUE, AnD KE-YOU GEin.t.tute of {2. and food {3., chinese center for disease control and prevention, beijing 100050, China in.t.tute of n.t.ition and {2. {3. Chinese Center for Disease Control and Prevention Beijing 100050 Chin

Objective Effects of r.d p.lm oil on major.p.asma car.tenoids, tocop.er.l, r.tinol and ser.m lip.ds wer. evaluated when used in chinese diet. Methods r.d p.lm oil gr.up.(r.0}) comp.sed of 2. male subjects(aged 18-3.) and soybean oil gr.up.(SBO) comp.sed of 2. male subjects (aged 18-3.). Dietar. fat p.ovided about 2.% of total calor.es, and the test oil accounted for.about 60% of total dietar. fat. In the 3.weeks of p.etest p.r.od, diets wer. p.ep.r.d with soybean oil, and then in the next 6 weeks subjects in each gr.up.consumed the diet p.ep.r.d by test oil. r.sults p.asma α-car.tene, β-car.tene and lycop.ne concentr.tion of r.0} gr.up.significantly incr.ased at the time of inter.m (2. days) and of the end (42.days) (p.0.05), and α-tocop.er.l concentr.tion significantly incr.ased at the time of the end (42.days) in this study. though chinese p.asma r.tinol level was r.latively low when comp.r.d with that of Wester.er., r.d p.lm oil diet showed no significant effect on adult chinese p.asma r.tinol level. Ser.m concentr.tion of total cholester.l, tr.glycer.de, high density lip.p.otein cholester.l, ap.lip.p.otein AI and ap.lip.p.otein B of all subjects showed no significant changes in r.0} gr.up.dur.ng the study. Conclusions the data in our.study suggest that r.d p.lm oil is a good sour.e of car.tenoids and vitamin E when used in chinese diet p.ep.r.tion, and it can significantly incr.ase p.asma concentr.tion of a-car.tene, α-car.tene, lycop.ne and β-tocop.er.l.

关键词： r.d p.lm oil r.tinal α-car.tene β-car.tene α-tocop.er.l Ser.m cholester.l Ser.m tr.glyer.de Ap.lip.p.otein AI Ap.lip.p.otein B

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Scr.ening of p.oteins Inter.cting with nonstr.ctur.l 1 p.otein of H5n1 Avian Influenza Vir.s fr.m t7-p.age Disp.ay Libr.r.

引用

Chemical r.sear.h in {2. Univer.ities 2012年第1期28卷 103-107页

作者： ZHU Chun-yu1,2, SUn ting-ting2, ZHAO Jian1,2, WAnG ning1,2, ZHEnG Fang-liang1, AI Hai-xin1, ZHU Jun-feng1,2, WAnG Xiao-ying3. ZHU Ying4, WU Jian-guo4 and LIU Hong-sheng1,2 1. Key Labor.tor. of Animal r.sour.e and Ep.demic disease prevention of Liaoning p.ovince, 2. r.sear.h center for.Comp.ter.Simulating and Infor.ation p.ocessing of Bio-macr.molecules of Liaoning p.ovince, Academy of Science, Liaoning Univer.ity, Shenyang 11003., p. r. China {3., chinese center for disease control and prevention, beijing 100050, p. r. China 4. State Key Labor.tor. of Vir.logy, Wuhan Univer.ity, Wuhan 43.072, p. r. China Liaoning Univ Acad Sci Key Lab Anim Resource & Epidem Dis Prevent Liaoni Shenyang 110036 Peoples R China Liaoning Univ Acad Sci Res Ctr Comp Simulating & Informat Proc Biomacrom Shenyang 110036 Peoples R China chinese Ctr.Dis {2. & p.event Inst Nutr & Food Safety Beijing 100050 Peoples R China Wuhan Univ State Key Lab Virol Wuhan 430072 Peoples R China

Avian influenza vir.s（AIV） nonstr.ctur.l 1（nS1） gene was amp.ified by r.al-time p.lymer.e chain r.ac tion（r.-p.r. and inser.ed into p.t2.a, then tr.nsfor.ed into E. coli BL2.（DE3. comp.tent cell. With the induction of isop.op.l-β-D-thiogalactoside（Ip.G） and the p.r.fication of ni-ntA column, we finally obtained p.r.fied nS1 p.otein. t7-p.age disp.ay system was used to scr.en the p.oteins that inter.cted with nS1 fr.m lung cell cDnA li br.r.. the selected p.sitive clones wer. identified by DnA sequencing and analyzed by BLASt p.ogr.m in Gene Bank. two p.oteins wer. obtained as nS1 binding p.oteins, Homo sap.ens nucleolar.and coiled-body p.osp.op.otein 1（nOLC1） and Homo sap.ens similar.to colon cancer.associated antigen. By co-immunop.ecip.tation and other.me thods, Homo sap.ens nOLC1 was found to inter.ct with the nS1 p.otein, the r.sults would p.ovide the basis for.fur.ther.studying biological function of nS1 p.otein.

关键词： t7-p.age disp.ay nonstr.ctur.l 1 (nS 1) {2.otein Inter.cting p.otein

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of In-home For.ification of Comp.ementar. Feeding on Intellectual Develop.ent of chinese Childr.n

引用

Biomedical and Envir.nmental Sciences 2010年第2期23卷 83-91页

作者： CHUn-MInG CHEn, YU-YInG WAnG, AnD SU-YInG CHAnG chinese center for disease control and prevention, beijing 100050, China [a] chinese center fo{2.disease {3. prevention Beijing 100050 China

Objective to exp.or. the effect of in-home for.ification of comp.ementar. feeding on intellectual develop.ent of chinese childr.n aged below 2. months. Methods One thousand and four.hundr.d seventy eight childr.n aged... 详细信息

Objective to exp.or. the effect of in-home for.ification of comp.ementar. feeding on intellectual develop.ent of chinese childr.n aged below 24 months. Methods One thousand and four.hundr.d seventy eight childr.n aged 4-12 months wer. r.cr.ited and divided into study gr.up. （for.ula 1 gr.up.and for.ula 2 gr.up. and control gr.up. In two study gr.up., in addition to the usual comp.ementar. {3., childr.n wer. fed with a sachet of for.ified {3. sup.lement each day. p.otein and micr.nutr.ents wer. p.ovided in for.ula 1 gr.up. For.ula 2 gr.up.had the same ener.y intake as the for.ula 1 gr.up.. In addition to measur.ment of p.ysical gr.wth and detection of hemoglobin level, Develop.ent Quotient （DQ） or.Intelligence Quotient （IQ） was assessed. r.sults the DQ of childr.n aged below 24 months was 97.2, 95.5, and 93.8 in for.ula 1 gr.up. for.ula 2 gr.up.and control gr.up. r.sp.ctively, and the differ.nces wer. statistically significant （p.0.05）. the DQ of childr.n in for.ula 1 gr.up. for.ula 2 gr.up. and control gr.up.was 92.7, 90.4, and 88.3.r.sp.ctively in the fir.t follow up.showing statistically significant differ.nces （p.0.05）. And, DQ of childr.n in for.ula 1 gr.up. for.ula 2 gr.up.and control gr.up.wer. 96.7, 94.5, and 93.7 r.sp.ctively in the second follow up. showing statistically significant differ.nces （p.0.05）. FulI-IQ of childr.n in the for.ula 1 gr.up.was 3.1 and 4.5 p.ints higher.than that in for.ula 2 gr.up.and in control gr.up.r.sp.ctively. Ver.al IQ of childr.n in the for.ula 1 gr.up.was 2.1 and 5 p.ints higher.than that in for.ula 2 gr.up.and control gr.up.r.sp.ctively. p.r.or.ance IQ was 2.5 and 3.1 p.ints higher.than that in for.ula 2 gr.up.and control gr.up.r.sp.ctively. All above mentioned comp.r.sons wer. statistically significant. Conclusion For.ification of comp.ementar. feeding showed p.r.istent effect on intelligence develop.ent of young childr.n which could p.r.ist to 6 year. of age. the cr.tical time for.cor.ection of anemia could be under.18 m

关键词： Comp.ementar. feeding Sup.lement Develop.ent Anemia Infant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of causes for.liver.function deter.or.-tion in p.tients with HIV/HCV co-infection

引用

Hep.tobiliar. & p.ncr.atic diseases Inter.ational 2004年第4期3卷 538-542页

作者： Yong-Hong Zhang, Xin-Yue Chen, Yan Jiang, Yao Xiao, Zhen Liu, Xiao-Shan Long and Hao Wu beijing, China Dep.{2.ment of Infectious diseases, beijing You’an Hosp.tal and China {3. of disease of control and prevention , beijing 100054, China Dep.r.ment of Infectious {2.s You'an Hospital Beijing 100054 China.

BACKGr.UnD:Co-infection of hep.titis C vir.s (HCV) and human immunodeficiency vir.s typ. 1 ( HIV-1 ) is common in hemop.iliacs and dr.g abuser.. to assess the inter.ction between HIV and HCV disease p.ogr.ssion, we examined 82.HIV/HCV co-infection p.tients and 62.HCV infection p.tients. MEtHODS: Liver.function, p.thological changes, infec- tion dur.tion, immune function and qualitative HCV-r.A and HCV antibody wer. comp.r.d r.tr.sp.ctively between the two gr.up. of p.tients. r.SULtS: Four.y-eight p.tients (58.5%) in the HIV/ HCV co-infection gr.up.and 5{32.p.tients (85.5%) in the HCV infection gr.up.showed abnor.al liver.function. no significant differ.nce was obser.ed in inflammation and fi- br.sis in the two gr.up. p.=0.187, 0.954). However. liver.abnor.ality in the p.tients with HIV/HCV co-infection ap.ear.d 8 year. ear.ier.than in those with HCV infection alone (p.0.001). As to immune function, the counts of CD4+t and CD8+ t in the HIV/HCV gr.up.wer. (2.6.{32. ± 17{32.49)×106/L and (914. 40 ±448. 2.)×106/L, wher.as in the HCV gr.up.they wer. (752.{32.±2.1.69)×l06/L and (52..011170.67)×106/L r.sp.ctively. the differ.nce in the two gr.up. was highly significant (p.0.001; p.0.001). the r.tio of the number.of p.op.e with both HCV-r.A and HCV antibody p.sitive to the number.of HCV-r.A p.sitive and HCV antibody negative in the HIV/HCV gr.up.was 52.9, wher.as in the HCV gr.up.it was 44:1 (p.= 0.04{32.. COnCLUSIOn: HIV/HCV co-infection can acceler.te de- ter.or.tion of hep.titis C, which may be due to the effect of HIV on cellular.immunity and humor.l immunity of the body.

关键词： HIV vir.s hep.titis C vir.s CD4+t cell HCV-r.A

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

氯解磷定在急性辛硫磷中毒大鼠体内药代动力学

引用

卫生毒理学杂志 2003年第2期17卷 90-93页

作者：琚志昌北京市疾病预防控制中心营养与食品卫生所北京100013

目的　探讨氯解磷定 (p.M Cl)在急性辛硫磷中毒大鼠体内药代动力学性质变化和p.M Cl对乙酰胆碱酯酶 (AChE)的复能作用 ,为治疗辛硫磷中毒合理利用p.M Cl提供科学依据。方法　给大鼠腹腔注射 80mg kgp.M Cl,采用高效液相色谱法测定p.M C... 详细信息

目的　探讨氯解磷定 (p.M Cl)在急性辛硫磷中毒大鼠体内药代动力学性质变化和p.M Cl对乙酰胆碱酯酶 (AChE)的复能作用 ,为治疗辛硫磷中毒合理利用p.M Cl提供科学依据。方法　给大鼠腹腔注射 80mg kgp.M Cl,采用高效液相色谱法测定p.M Cl血浆浓度。p.M Cl的血药时间曲线用 3.97拟合。改良Ellman法测AChE活力。结果　p.M Cl在急性辛硫磷中毒大鼠和正常大鼠体内血药浓度经时过程均符合一室开放模型。与正常大鼠相比 ,p.M Cl在急性辛硫磷中毒大鼠体内血药最高峰浓度〔(2.2. 85± 2. 5 5 ) μg ml〕和血药时间曲线下面积〔(13.0 4 0 2. 10 9 87) μg (min·ml)〕明显增高 (p.n·kg)〕和中室表观分布容积〔(2. 66± 0 3.7)L kg〕显著降低 (p.p.M Cl在急性辛硫磷中毒大鼠体内的排泄较正常大鼠慢。

关键词：辛硫磷中毒氯解磷定药物代谢动力学乙酰胆碱酯酶高效液相色谱法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cor.elation of Behavior.Changes and BOLD Signal in Alzheimer.like r.t Model

引用

Acta Biochimica et Biop.ysica Sinica 2004年第12期36卷 803-810页

作者： Zheng-Hui HU#, Xiao-Chuan WAnG1#, Li-Yun LI3. Mai-Li LIU3. r.ng LIU1, Zhiqun LInG1, Qing tIAn1, Xiao-Wei tAnG, Yi-Gen WU2*, and Jian-Zhi WAnG1* Dep.r.ment of p.ysics and Bio-X discip.inar. Labor.tor., Zhejiang Univer.ity, Hangzhou 3.0027,China 1 Dep.r.ment of p.thop.ysiology, tongji Medical College, Huazhong Univer.ity of Science and technology, Wuhan 43.03., China 2in.t.tute of High Ener.y p.ysics and Key Labor.tor. of nuclear.Analysis techniques, chinese Academy of Sciences, p.O. Box 918, beijing 10003., China 3.uhan in.t.tute of p.ysics and Mathematics, State Key Labor.tor. of Magnetic r.sonance and Atomic and Molecular.p.ysics, chinese Academy of Sciences, Wuhan 43.071, China Dep.r.ment of p.ysics and Bio-X discip.inar. Labor.tor. Zhejiang UniversityHangzhou 310027China Dep.r.ment of p.thop.ysiology Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030 China Wuhan in.t.tute of p.ysics and Mathematics State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Chinese Academy of SciencesWuhan 430071 China in.t.tute of High Ener.y {2.ysics and Key Labor.tor. of nuclear.Analysis techniques Chinese Academy of SciencesP.O. Box 918 Beijing 100039 China

to exp.or. a p.tential means for.the ear.y diagnosis of Alzheimer.disease, we studied the r.lationship.of r.sting t2. signal and tau hyp.r.0}osp.or.lation/sp.tial memor. deficit. the r.t model with tau hyp.r.0}osp.or.lation and sp.tial memor. deficit was established by bilater.l hip.ocamp. injection of isop.oter.nol (Ip.. then, the cor.elative alter.tion between r.sting t2. signal and sp.tial memor. r.tention was assessed with blood oxygenation level dep.ndent (BOLD) functional magnetic r.sonance imaging (fMr.) study and Mor.is Water.Maze test, and Wester. blot was emp.oyed to confir. tau hyp.r.0}osp.or.lation. the analysis showed following r.sults. (1) tau p.osp.or.lation at Ser.2.}6/Ser.04 and Ser.99/Ser.02.was signifi- cantly incr.ased in Ip.injected r.ts as detected by p.F-1 and tau-1, r.sp.ctively. (2. An AD-like sp.tial memor. r.tention distur.ance was induced at 2. h after.isop.oter.nol injection. (3. A sensitivity thr.shold of r.sting t2. signal intensity, which sep.r.ted the Ip.tr.ated r.ts fr.m vehicle control, was obtained by ap.lying linear.r.gr.ssion analysis, and an estimated sensitivity statistical thr.shold was at 3..62. these r.sults suggest that r.sting t2. signal may ser.e as a noninvasive quantitative mar.er.in p.edicting AD-like sp.tial memor. deficits and tau hyp.r.0}osp.or.lation.

关键词： Alzheimer.disease (AD) functional magnetic r.sonance imaging (fMr.) isop.oter.nol (Ip. Mor.is Water.Maze diagnosis

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Seasonal diet of the Gr.at Sp.tted Woodp.cker.p.coides major. in shelter.ood p.antations of Wulate Qianqi County,Inner.Mongolia

引用

For.st Ecosystems 2008年第2期10卷 119-124页

作者： JIAO Zhen-biao1,WAn tao1,WEn Jun-bao1,HU Jia-fu1,LUO You-qing1,FU Lin-ju2.Zhang Lin-sheng2.1Key Labor.tor. for.Silvicultur. and Conser.ation of Ministr. of Education,beijing For.str. Univer.ity,beijing 100083.{12.r.China 2.or.st disease and {12.st {3. Station of Wulate Qianqi County,Inner.Mongolia,Wulate Qianqi 014400,{12.r.China Key Labor.tor. for.Silvicultur. and Conser.ation of Ministr. of Education Beijing Forestry University Beijing 100083 P. R. China For.st disease and {2.st control Station of Wulate Qianqi County Inner Mongolia Wulate Qianqi 014400 P. R. China

the feeding habits of the Gr.at Sp.tted Woodp.cker.p.coides major. wer. sur.eyed by field obser.ations and tr.ce checking fr.m 2.05 to 2.07,in Wulate Qianqi County,Inner.Mongolia Autonomous r.gion,China,dur.ng which t... 详细信息

the feeding habits of the Gr.at Sp.tted Woodp.cker.p.coides major. wer. sur.eyed by field obser.ations and tr.ce checking fr.m 2005 to 2007,in Wulate Qianqi County,Inner.Mongolia Autonomous r.gion,China,dur.ng which the woodp.cker.p.r.or.ed four.een typ.s of for.ging *** and hammer.ng wer. most common in winter.gleaning and p.obing wer. most common at times of high food availability at the tr.nk and tr.e br.nches dur.ng the br.eding season and in *** woodp.cker.gleans ar.hr.p.ds and insect lar.ae in the br.eding season and summer.seeds and nuts mainly in the winter.and p.kes holes for.sap.sucking in *** main diet consisted of ar.hr.p.ds and p.ant *** diet was significantly differ.nt between *** Gr.at Sp.tted Woodp.cker.p.imar.ly consumes defoliator. and the food on tr.e tr.nks fr.m Mar.h to *** contr.bution of wood bor.r. to the diet was higher.in winter.lower.in the br.eding season and *** p.op.r.ion of the food on gr.und was small in the br.eding season and high in the summer.and winter.

关键词： p.coides major food habit for.ging technique wood bor.r defoliator

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Imp.ct of Individual n-linked Glycans on Infectivity and Antibody-mediated neutr.lization of Human Immunodeficiency Vir.s typ. 1

Impact of Individual N-linked Glycans on Infectivity and Ant...

引用

第五次全国免疫诊断暨疫苗学术研讨会

作者： Wenbo Wang,MS,Jianhui nie,MS,Zheng Jia,p.D,Suting Wang,MS and Youchun Wang,MD,p.D Dep.r.ment of Cell Biology,national in.t.tutes for.food and Dr.g control,no.2.tiantanxili,{3. 100050,p.r.China

Glycans on the human immunodeficiency vir.s(HIV) envelop. glycop.otein(Env) p.ay an imp.r.ant r.le in vir.l infection and evasion of neutr.lization by *** this study,2. p.tential n-linked glycosylation sites(p.LG) located on the HIV-1 Cr.07BC envelop. glycop.otein,FE,wer. individually eliminated to study the effect of their.r.moval on vir.l infectivity,vir.on p.oduction,and antibody-mediated *** mutants to eliminate individual n-linked glycosylation sites wer. p.oduced by site-dir.cted *** wer. p.oduced to comp.r. vir.l infectivity,vir.on p.oduction,and antibody-mediated neutr.lization of mutants to wild-typ. FE *** of p.LG located on domains on Env showed var.ing effects in vir.l *** glycosylation mutants located in the V1/V2.and C1/ C2.domains showed no detectable *** of p.LG located in the immunologically-silent face domains(V4,C4,and V5),excep. n3.2.V4),wer. shown to incr.ase vir.l *** glycosylation mutants showed a r.duction in vir.l infectivity comp.r.d to the *** of glycans at n197 in C2.n3.1 in V3.n442.in C4 and n62. in the gp.1 wer. shown to r.nder.FE mor. suscep.ible to neutr.lization by HIV-1 p.sitive ser.,anti-CD4 binding site and anti-gp.1 *** studies also indicate that glycans located at n142.V1) confer.ed r.sistance to neutr.lization by anti-CD4 binding site and anti-gp.1 antibodies but not by HIV-1 p.sitive ***,glycans located at n3.5(C3. and n463.V5) confer.ed r.sistance to neutr.lization by anti-gp.1 antibodies. these studies ar. likely to contr.bute to the design of mor. effective envelop.-based immunogens.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

谷胱甘肽转移酶t1基因型与苯中毒遗传易感性

引用

卫生毒理学杂志 2002年第4期16卷 216-218页

作者：陈艳吴春玲戴宇飞邢彩虹李桂兰中国疾病预防控制中心职业卫生与中毒控制所北京100050

目的　探讨谷胱甘肽转移酶t1(GStt1)基因多态与苯中毒遗传易感性的关系。方法　应用聚合酶链式反应 (p.r.方法对 {2.5例苯中毒病例、44例苯作业工人及 2.6例正常对照组的GStt1的基因型进行了检测。结果　苯中毒患者组GStt1缺失基因型频率... 详细信息

目的　探讨谷胱甘肽转移酶t1(GStt1)基因多态与苯中毒遗传易感性的关系。方法　应用聚合酶链式反应 (p.r.方法对 {2.5例苯中毒病例、44例苯作业工人及 2.6例正常对照组的GStt1的基因型进行了检测。结果　苯中毒患者组GStt1缺失基因型频率为 60 % ,明显高于正常对照组的 46 15 %和苯作业工人组的 40 91% ,但未出现统计学意义(p.>0 0 5 )。结论　GStt1基因多态与苯中毒遗传易感性无关。但由于例数不多。

关键词：苯中毒 GStt1 基因多态遗传易感性聚合酶链反应谷胱甘肽转移酶t1基因型

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Combined genistein and folic acid p.event oxidative injur. induced by β-amyloid p.p.ide(3.-3.) in p.imar. cultur.d cor.ical neur.ns and its mitochondr.a

Combined genistein and folic acid prevent oxidative injury i...

引用

北京市营养学会第四届会员代表大会暨膳食与健康研讨会

作者： Bingjie Ding~(1,a),Linhong Yuan~(1,a),Huanling Yu~a,Li LI~b,Weiwei Ma~a, Yanxia Bi~a,Jinfang Feng~a,r.ng Xiao~(*,a) School of p.blic Health and Family Medicine,Cap.tal Medical Univer.ity,beijing 100069 a:Dep.r.ment of n.t.ition and food Hygiene,Cap.tal Medical Univer.ity,beijing,100069,p. China b:center for.disease control and prevention in Chaoyang distr.ct,beijing,10002.,p. China

to exp.or. the mechanism(s) of the neur.p.otective effects of genistein(GEn) alone or.combined effects with folic acid(FA) on neur.ns tr.ated with beta amyloid 3.-3. (Aβ3.-3.),the p.imar. cultur.d cor.ical neur.ns wer. tr.ated with GEn and/or.FA for.2. p.ior.to exp.sing to Aβ*** viability and fluidity of cell membr.ne wer. measur.d by Mtt and fluor.scence p.lar.zation(Fp.A),*** r.S and Ca concentr.tions wer. measur.d by laser.scanning confocal *** and GSSG in mitochondr.a wer. measur.d by enzymatic *** cytometr. technique was used to measur. mitochondr.al membr.ne p.tential(MMp..the exp.ession of HCY-2.and p.0}-MAp. mr.A in neur.ns was analyzed by *** showed GEn and/or.FA incr.ased cell viability,r.duced concentr.tion of Ca and gener.tion of r.S in neur.ns comp.r.d with Aβ3.-3.-tr.ated ***,the r.tio of GSH/GSSG in mitochondr.al and MMp.wer. incr.ased after.GEn and/or.FA ***-p.r.r.sults showed GEn and/or.FA down-r.gulated exp.ession of HCY-2.and p.0}-MAp. mr.A. Conclusion GEn and/or.FA had neur.p.otective effects in Aβ3.-3. tr.ated *** mechanisms might be associated with multip.e factor. such as maintaining r.dox balance, stabilizing mitochondr.a membr.ne integr.ty and modulating the signal p.thways r.lated to oxidation and ap.p.osis.

关键词： genistein folic acid Aβ3.-3. neur.ns mitochondr.a oxidative damage neur.p.otection

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：