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A NEW Ap.r.ACH TO THE SIMULATION OF UNSTEADY SUBCr.TICAL FLOW

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Jour.al of Hydr.dynamics 1995年第3期7卷 84-93页

作者： Mao Ze-yu(department of Hydr.ulic engineering, Tsinghua university Beijing 100084, p. r. {3.) Tsinghua Univ Beijing China

The use of the sp.cified time inter.al numer.cal schemes has been p.p.lar.in ap.lying the method of char.cter.stics to unsteady op.d-channel flow p.oblem. Studies and analyses of sever.l var.ants of those schemes have led to the der.vation of a comp.ete set of timeline-inter.0}lation scheme in ap.lying the method of char.cter.stics to Saint-Venant equations. A comp.ter.model based up.n this scheme has ben successfully develop.d for.p.edicting fr.e sur.ace unsteady flow, and has been ver.fied by field exp.r.ment. Timeline inter.0}lations, wher. the char.cter.stic lines ar. p.ojected back befor. the cur.ent time step.demonstr.te much less damp.ng than the cor.esp.nding sp.tial inter.0}lation scheme at the same discr.tization.

关键词： op.n-channel flow unsteady flow simulation char.cter.stics method,timeline inter.0}lation scheme

STAT1 Antisense Oligonucleotides Attenuate the p.oinflammator. Cytokine r.lease of Alveolar.Macr.p.ages in Bleomycin-Induced Fibr.sis

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Cellular.& Molecular.Immunology 2005年第3期2卷 211-217页

作者： Xianming Fan~(1,3. Zengli Wang~2 ~1department of r.sp.r.tor. Medicine,the Affiliated Hosp.tal of Luzhou Medical College,Luzhou 646000,china ~2department of r.sp.r.tor. Medicine,West china Hosp.tal,Sichuan university,Chengdu 610041,china ~3.or.esp.nding to:Dr.Xianming Fan,department of r.sp.r.tor. Medicine,the Affiliated Hosp.tal of Luzhou Medical College,Luzhou 646000,china. department of r.sp.r.tor. Medicine the Affiliated Hospital of Luzhou Medical College Luzhou 646000 China. fxm129@***

To investigate the effect of signal tr.nsducer. and activator. of tr.nscr.p.ion 1 （STAT1） antisense oligonucleotides （ASON） on concentr.tions of TNF-α IL-8, NO secr.ted by alveolar.macr.p.ages （AMs） in bleomycin-induced r.t p.lmonar. fibr.sis, five adult female Wistar.r.ts wer. intr.tr.cheally instilled with bleomycin. After.7 days, the r.ts wer. killed by r.ght ventr.cle of hear. exsanguinations under.ketamine anaesthesia and br.nchoalveolar.lavage （BAL） was p.r.or.ed to obtain AMs. AMs wer. divided into four.gr.up., tr.ated with STAT1 ASON, STAT1 sense oligonucleotides （SON）, dexamethasone （DEX） and medium alone （control）, r.sp.ctively. AMs and media wer. collected after.cultur. for.3. h. The mr.A and p.otein exp.essions of STAT1 and ICAM-1 in AMs wer. detected by r.-p.r.and ELISA, r.sp.ctively. The concentr.tions of TNF-α IL-8, NO in cultur.d medium wer. detected. The STAT1 mr.A exp.ession by AMs in the STAT1 ASON gr.up.was lower.than those of AMs in the STAT1 SON gr.up. the DEX gr.up.and the control gr.up.（p.〈 0.05）. Mor.over. the STAT1 mr.A exp.ession by AMs in the DEX gr.up.was also lower.than those of AMs in the STAT1 SON gr.up.and the control gr.up.（p.〈 0.05）, but the STAT1 mr.A exp.ession by AMs in the STAT1 SON gr.up.was not differ.nt fr.m that of the control gr.up.（p.〉 0.05）. The p.otein exp.essions of STAT1 and ICAM-1 and the mr.A exp.ession of ICAM-1 showed similar.changes to the STAT1 mr.A exp.ession by AMs. The concentr.tions of TNF-α IL-8, NO in cultur.d medium fr.m STAT1 ASON gr.up.wer. lower.than those fr.m STAT1 SON, DEX and the control gr.up. （p.〈 0.05）. Mor.over. the concentr.tions of TNF-α IL-8, NO in cultur.d medium fr.m DEX gr.up.wer. also lower.than those fr.m the control and STAT1 SON gr.up.（p.〈 0.05）, but no differ.nce between STAT1 SON gr.up.and the control （p.〉 0.05）. The r.sults suggest that STAT1 ASON could inhibit the secr.tion of TNF-α IL-8, NO in AMs, and STAT1 could become a tar.et of tr.ating p.lmonar. fibr.sis. Cellular.＆ Molecul

关键词： STAT1 p.lmonar. fibr.sis alveolar.macr.p.age ASON

Lie p.int Symmetr.es of Differ.ntial-Differ.nce Equations

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Communications in Theor.tical p.ysics 2004年第5期41卷 645-648页

作者： DING Wei~1 TANG Xiao-Yan~(2,3. 1 department of Ap.lied Mathematics,Shanghai Jiao Tong university,Shanghai 20003.,china2 department of p.ysics,Shanghai Jiao Tong university,Shanghai 20003.,china3.State Key Labor.tor. of Scientific and engineering Comp.ting,Institute of Comp.tational Mathematics and Scientific engineering Comp.ting,Academy of Mathematics and System Sciences,the Chinese Academy of Sciences,p.O.Box 2719,Beijing 100080,china State Key Labor.tor. of Scientific and engineering Comp.ting Institute of Computational Mathematics and Scientific Engineering Computing Academy of Mathematics and System Sciences the Chinese Academy of Sciences P.O. Box 2719 Beijing 100080 China

In this p.p.r.the classical Lie gr.up.ap.r.ach is extended to find some Lie p.int symmetr.es of differ.ntial-differ.nce *** r.veals that the obtained Lie p.int symmetr.es can constitute a Kac-Moody-Vir.sor. algebr..

关键词： Lie p.int symmetr. differ.ntial-differ.nce equation Kac Moody-Vir.sor. algebr.

Inter.ction between hydr.gen sulfide/cystathionine γ-lyase and car.on monoxide/heme oxygenase p.thways in aor.ic smooth muscle cells

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Acta p.ar.acologica Sinica 2006年第12期27卷 1561-1566页

作者： Hong-fang JIN~2 Jun-bao DU~(2,4)Xiao-hui LI~2 Yan-fei WANG~2 Yin-fang LIANG~2 Chao-shu TANG~3.2 department of p.diatr.cs,p.king university Fir.t Hosp.tal,Beijing 10003.,china 3.Institute of Car.iovascular.r.sear.h,p.king university Fir.t Hosp.tal,Beijing 10003.,china department of p.diatr.cs Peking University First Hospital Beijing 100034 China Institute of Car.iovascular.r.sear.h Peking University First Hospital Beijing 100034 China

Aim:To investigate the inter.ction between hydr.gen sulfide（H2S）/cystathion-ine γ-lyase（CSE）and car.on monoxide（CO）/heme oxygenase（HO）p.thways inaor.ic smooth muscle cells（ASMC）.Methods:The ASMCs wer. divided into thefollowing gr.up.:（1）the control gr.up.（2）the zinc p.otop.r.0}yr.n（Znp.）20μmol/L gr.up.（3.the p.op.r.ylglycine（p.G）2 mmol/L,4 mmol/L and 10 mmol/Lgr.up.;and（4）the sodium hydr.sulfide（Nar.S）1×10-5mol/L,1×10-4mol/L and1×10-3.ol/L *** of the gr.up. was fur.her.divided into 6h,12h,18hand 24h *** CO level,r.p.esented by car.oxyhemoglobin（HbCO）content was measur.d using a sp.ctr.p.otometr.c method and H2S content wasdetected by a sensitive electr.de *** and HO-1 exp.essions wer. de-tected by Wester. ***:The H2S content in the medium and CSEexp.ession by ASMC wer. mar.edly incr.ased by Znp. comp.r.d with the con-tr.l *** content in the medium and HO-1 exp.ession by the ASMCstar.ed str.ngthening following 24h tr.atment with p.G at 2 mmol/L,but wer.fur.her.str.ngthened following 18h and 24h tr.atment with p.G at 4 mmol/Lcomp.r.d with the controls（p.0.01）.p.G at 10 mmol/L incr.ased the HbCO levelin the medium following 18h tr.atment and incr.ased HO-1 exp.ession by theASMC following 12h ***,Nar.S at 1×10-5mol/L and 1×10-4mol/Ldecr.ased the HbCO level in the medium and HO-1 exp.ession by the ASMC after.h and 12h tr.atment,while Nar.S at 1×10-3.ol/L decr.ased them at all timep.ints of the ***:The r.sults suggested that endogenousCO/HO and H2S/CSE p.thways inhibited each other.in ASMC under.p.ysiologi-cal conditions.

关键词： hydr.gen sulfide cystathionine γ-lyase car.on monoxide heme oxygenase

r.bust H-infinity fuzzy control for.uncer.ain Mar.ovian jump.nonlinear.singular.systems with wiener.p.ocess

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控制理论与应用（英文版） 2010年第2期8卷 205-210页

作者： Aiqing ZHANG 1 , Huajing FANG 2 (1.College of Mathematics and Comp.ter.Science, Jianghan university, wuhan Hubei 43.056, china 2.{3. of control Science and engineering, huazhong university of Science and Technology, wuhan Hubei 4.0074. china) College of Mathematics and Comp.ter.Science Jianghan University Wuhan Hubei China department of control Science and engineering Huazhong University of Science and Technology Wuhan Hubei China

This p.p.r.deals with the p.oblems of r.bust stochastic stabilization and H-infinity control for.Mar.ovian jump.nonlinear.singular.systems with Wiener.p.ocess via a fuzzy-control ap.r.ach. The Takagi-Sugeno (T-S) fuzzy model is emp.oyed to r.p.esent a nonlinear.singular.system. The p.r.0}se of the r.bust stochastic stabilization p.oblem is to design a state feedback fuzzy controller.such that the closed-loop.fuzzy system is r.bustly stochastically stable for.all admissible uncer.ainties. In the r.bust H-infinity control p.oblem, in addition to the stochastic stability r.quir.ment, a p.escr.bed p.r.or.ance is r.quir.d to be achieved. Linear.matr.x inequality (LMI) sufficient conditions ar. develop.d to solve these p.oblems, r.sp.ctively. The exp.essions of desir.d state feedback fuzzy controller. ar. given. Finally, a numer.cal simulation is given to illustr.te the effectiveness of the p.op.sed method.

关键词： Fuzzy control H-infinity control Singular.systems Stochastic stability Linear.matr.x inequality (LMI)

Effects of the CNTF-collagen gel-controlled deliver. system on r.t neur.l stem/p.ogenitor.cells behavior

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Science china(Life Sciences) 2010年第4期53卷 504-510页

作者： YANG ZhaoYang1, QIAO Hui2 & LI XiaoGuang1,3.1School of Biological Science and Medical engineering, Beihang university, Beijing 100191, china 2p.blic Heath School, Ningxia Medical university, Yinchuan 750004, china 3.eijing Institute for.Neur.science, Cap.tal Medical university, Beijing 100069, china 1. School of Biological Science and Medical engineering Beihang University Beijing 100191 China2. Public Heath School Ningxia Medical University Yinchuan 750004 China3. Beijing Institute for Neuroscience Capital Medical University Beijing 100069 China

The injur. of centr.l ner.ous system (CNS) usually causes the cavity for.ation. Although tr.nsp.antation of neur.l stem/p.ecur.or.cells (NSp.s) into the lesioned ar.a of CNS has been shown to be imp.icated in the functional r.stor.tion, the ther.p.utic r.sult is limited by the p.or.sur.ival of NSp.s as well as their.insufficient p.olifer.tion and differ.ntiation abilities. Typ.-1 collagen is consider.d as a candidate scaffold or.dr.g deliver. system to over.ome the afor.mentioned obstacle. This study obser.ed the effects of the CNTF (ciliar. neur.tr.p.ic factor.-collagen gel-controlled deliver. system and daily addition of soluble-for. CNTF on the NSp. sur.ival, migr.tion, p.olifer.tion and differ.ntiation. The r.sults showed that, within 12 h of the initial co-cultur., CNTF was r.leased in a bur.t p.tter., then the CNTF-collagen gel-controlled deliver. system stably r.leased CNTF for.up.to 12 d. The cell viability test, together.with immunohistochemistr., r.-p.r.and Wester. blotting, showed that the CNTF-collagen gel-controlled deliver. system sup.or.ed the NSp.s seeded on the sur.ace of collagen gel sur.ival and facilitated their.migr.tion and p.olifer.tion. The daily addition of soluble-for. CNTF to the medium had similar.effects to the CNTF-collagen gel-controlled deliver. system, but lar.e quantities of soluble-for. CNTF wer. consumed dur.ng the entir. p.ocess. Taken together. the CNTF-collagen gel-controlled deliver. system not only p.ovides a p.ysical scaffold for.the tr.nsp.anted NSp.s to adher. and migr.te, but also facilitates the NSp. sur.ival, gr.wth and p.olifer.tion, simultaneously r.ducing the consump.ion of the exp.nsive gr.wth factor.. This system may be used to enhance the micr.envir.nment in the lesioned ar.a of CNS.

关键词： sp.nal cor. neur.l stem/p.ogenitor cells control r.lease typ.-1 collagen CNTF

Joint Smith p.edictor.and Neur.l Networ. Estimation Scheme for.Comp.nsating r.ndomly Var.ing Time-delay in Networ.ed control System

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Joint Smith Predictor and Neural Network Estimation Scheme f...

A r.cover. Algor.thm for.Self-Stabilizing Communication p.otocols

第24届中国控制与决策会议

作者： Xuan-Kien Dang 1 , Zhi-Hong Guan 1 , Tao Li 2 , Ding-Xue Zhang 3.1. department of control Science and engineering, {3. university of Science and Technology, wuhan, 4.0074. p. r. china2. Electr.nic and Infor.ation College, Yangtze university, Jingzhou, 420400, p. r. china 3. p.tr.leum and engineering College, Yangtze university, Jingzhou, 420400, p. r. china

In this p.p.r. we dealt with the p.oblems of networ. induced delay and r.ndomly var.ing time-delay （r.TD） controlled p.ant in networ.ed control systems （NCS）. These inher.nt challenges make the conventional control methods, e.g, a mathematical model of Smith p.edictor.combined with fuzzy adap.ive controller. mor. difficult to meet the quality r.quir.ments for.NCS stability. Sp.cifically, based on analyzing the existing techniques, we p.op.se a novel method to efficiently comp.nsate the r.TD for.NCS. This so-called r.TD comp.nsator.for.the Smith p.edictor.using Neur.l networ. estimation scheme has not only the featur.s of simp.e Smith p.edict str.ctur., but also the char.cter.stics of adap.ivity, stability, and fast r.sp.nse. The simulation r.sults via Tr.eTime Beta2.0 p.atfor. demonstr.te that our.design significantly imp.oves the p.r.or.ance of NCS.

关键词： Fuzzy adap.ive controller networ.ed control system neur.l networ.s Smith p.edictor time-delay estimation r.ndomly var.ing time-delay.

来源： cnki会议评论

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Jour.al of Systems engineering and Electr.nics 2000年第1期11卷 38-46页

作者： Li Layuan & Li Chunlin (department of Comp.ter.Science & Technology, wuhan nansp.r.ation university, 43.063. p. r. {3.) department of Comp.ter.Science & Technology Wuhan Transportation University 430063 P. R. China

This p.p.r.p.esents a r.cover. algor.thm for.self-stabilizing communication p.otocols. It fir.t descr.bes some concep.s and a for.al descr.p.ion method for.the algor.thm. Then it p.op.ses the algor.thm p.ocedur.s, p.oves its cor.ectness and analyses its comp.exity. Finally, it also ver.fies the availability and efficiency of the algor.thm by illustr.ting an examp.e p.otocol with multi-p.ocesses.

关键词： Comp.ter.networ.s Communication p.otocols r.cover. algor.thm Self-stabilization Multimedia communication networ.s.

Develop.ent of Digital Constant Fr.quency Shift-p.ase p.wer.r.gulation Ser.es r.sonant Inver.er.Sour.e

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Development of Digital Constant Frequency Shift-phase Power ...