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动物营养学报 2024年第8期 4754-4754页

作者： institute of Scientific and Technical Information of china 中国科学技术信息研究所

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中国科技核心期刊(中国科技论文统计源期刊)收录证书

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中国医学影像学杂志 2024年第5期 529-529页

作者： institute of Scientific and Technical Information of china 中国科学技术信息研究所

CERTIFICATE OF SOURCE JOURNAL FOR CHINESE SCIENTIFIC AND TECHNICAL PAPERS AND CITATIONS中国医学影像学杂志经过多项学术指标综合评定及同行专家评议推荐,贵刊被收录为“中国科技核心期刊”(中国科技论文统计源期刊)。特颁发此证书。

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On the fundamental equation of nonequilibrium statistical physics—Nonequilibrium entropy evolution equation and the formula for entropy production rate

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Science china(Physics,Mechanics & Astronomy) 2010年第12期53卷 2194-2215页

作者： XING XiuSan Department of Physics, beijing institute of Technology, beijing 100081, china Department of Physics Beijing Institute of Technology Beijing China

In this paper the author presents an overview on his own research works. More than ten years ago, we proposed a new fundamental equation of nonequilibrium statistical physics in place of the present Liouville equation. That is the stochastic velocity type’s Langevin equation in 6N dimensional phase space or its equivalent Liouville diffusion equation. This equation is time-reversed asymmetrical. It shows that the form of motion of particles in statistical thermodynamic systems has the drift-diffusion duality, and the law of motion of statistical thermodynamics is expressed by a superposition of both the law of dynamics and the stochastic velocity and possesses both determinism and probability. Hence it is different from the law of motion of particles in dynamical systems. The stochastic diffusion motion of the particles is the microscopic origin of macroscopic irreversibility. Starting from this fundamental equation the BBGKY diffusion equation hierarchy, the Boltzmann collision diffusion equation, the hydrodynamic equations such as the mass drift-diffusion equation, the Navier-Stokes equation and the thermal conductivity equation have been derived and presented here. What is more important, we first constructed a nonlinear evolution equation of nonequilibrium entropy density in 6N, 6 and 3 dimensional phase space, predicted the existence of entropy diffusion. This entropy evolution equation plays a leading role in nonequilibrium entropy theory, it reveals that the time rate of change of nonequilibrium entropy density originates together from its drift, diffusion and production in space. From this evolution equation, we presented a formula for entropy production rate (i.e. the law of entropy increase) in 6N and 6 dimensional phase space, proved that internal attractive force in nonequilibrium system can result in entropy decrease while internal repulsive force leads to another entropy increase, and derived a common expression for this entropy decrease rate or anothe

关键词： stochastic velocity type’s Langevin equation in 6N dimensional phase space drift-diffusion duality nonequilibrium entropy evolution equation entropy diffusion formula for entropy production rate entropy change from internal interaction a

Two－Side　Electron　Beam　Pumping　System　For　Hundred－Joule－Level　KrF　Excimer　Laser

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Chinese Journal of Lasers 1996年第6期B5卷 485-491页

作者： MA Weiyi SHAN Yusheng ZHOU Kungong WANG Youtian ZHANG Dong WU Fangfang YANG Zhe WANG Naiyan (china institute of atomic energy, P. O. for 275-7, beijing 102.13,china) china Inst of atomic energy Beijing China

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Ｔｗｏ－ＳｉｄｅＥｌｅｃｔｒｏｎＢｅａｍＰｕｍｐｉｎｇＳｙｓｔｅｍＦｏｒＨｕｎｄｒｅｄ－Ｊｏｕｌｅ－ＬｅｖｅｌＫｒＦＥｘｃｉｍｅｒＬａｓｅｒ￥ＭＡＷｅｉｙｉ；ＳＨＡＮＹｕｓｈｅｎｇ；ＺＨＯＵＫｕｎｇｏｎｇ；ＷＡＮＧＹｏｕｔｉａｎ；ＺＨＡＮＧＤｏｎｇ；...

关键词： KrF excimer laser pulsed power system

SYNTHESIS　OF　BENZO－15－CROWN－5　PHENOL－FORMALDEHYDE　RESIN　FOR　LITHIUM　ISOTOPE　SEPARATION

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Chinese Chemical Letters 1996年第3期7卷 289-292页

作者： YOU Heng SHI Qun YAN Duo Yuan WANG Xiao Zhi ZHANG Zhong Guo DENG Hui Bao LU (institute of Photographic Chemistry, Academia Sinica, beijing, 100101)(china institute of atomic energy, beijing, 102.13) institute of Photographic Chemistry Academia Sinica Beijing 100101 china institute of atomic energy Beijing 102413

Four kinds of phenol-formaldehyde resins containing benzo-15-crown-5 ether were synthesized for lithium isotope *** adsolptioncapacity and isotope effect of Liin these resins have been investigated. Singleseparation factors 1.023￣1.056 were obtained with batch method from isotoperatios, 6Li and Li'were enriched in tile resin phase and liquid phase, respectively.

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Parameter identification theory of a complex model based on global optimization method

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Science china(Physics,Mechanics & Astronomy) 2008年第11期51卷 1722-1732页

作者： QU Jie1, JIN QuanLin2 & XU BingYe3 1 College of Automotive Engineering, South china University of Technology, Guangzhou 510640, china 2 beijing Research institute of Mechanical and Electrical Technology, beijing 100083, china 3 Department of Engineering Mechanics, Tsinghua University, beijing 100084, china College of Automotive Engineering South China University of Technology Guangzhou China beijing Research institute of Mechanical and Electrical Technology Beijing China Department of Engineering Mechanics Tsinghua University Beijing China

With the development of computer technology and numerical simulation technology, computer aided engineering (CAE) technology has been widely applied to many fields. One of the main obstacles, which hinder the further application of CAE technology, is how to successfully identify the parameters of the selected model. An elementary framework for parameter identification of a complex model is provided in this paper. The framework includes the construction of objective function, the design of the optimization method and the evaluation of the identified results, etc. The parameter identification process is described in this framework, taking the parameter identification of the superplastic constitutive model considering grain growth for Ti-6Al-4V at 927°C as an example. The objective function is the weighted quadratic sums of the difference between the experimental and computational data for the stress-strain relationship and the grain growth relationship; the designed optimization method is a hybrid global optimization method, which is based on the feature of the objective function and incorporates the strengths of genetic algorithm (GA), the Levenberg-Marquardt algorithm and the augmented Gauss-Newton algorithm. The reliability evaluation of parameter identification result is made through the comparison between the calculated and experimental results and between the theoretical values of the parameters and the identified ones.

关键词： constitutive model parameter identification theory inverse analysis global optimization

Cancer immunotherapy with envelopedself-amplifying mRNA CARG-2020 thatmodulates IL-12,IL-17 and PD-L1 pathways toprevent tumor recurrence

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Acta Pharmaceutica Sinica B 2024年第1期14卷 335-349页

作者： Ju Chen Bhaskara Reddy Madina Elham Ahmadi Timur Olegovich Yarovinsky Marie Marthe Krady Eileen Victoria Meehan Isabella china Wang Xiaoyang Ye Elise Pitmon Xian-Yong Ma Bijan Almassian Valerian Nakaar Kepeng Wang Department of Immunology School of MedicineUniversity of Connecticut Health CenterFarmingtonCT 06030USA CaroGen Corporation FarmingtonCT 06030USA The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine Foshan Hospital of Traditional Chinese MedicineFoshan 528000China The Loomis Chaffee School WindsorCT 06095USA

Targeting multiple immune mechanisms may overcome therapy resistance and further improve cancer immunotherapy for ***,we describe the application of virus-like vesicles(VLV)for delivery of three immunomodulators alone and in combination,as a promising approach for cancer *** vectors were designed to deliver single chain interleukin(IL)-12,shorthairpin RNA(shRNA)targeting programmed death ligand 1(PD-L1),and a dominant-negative form of IL-17 receptor A(dn-IL17RA)as a single payload or as a combination *** delivery of the VLV vector expressing IL-12 alone,as well as the trivalent vector(designated CARG-2020)eradicated large established ***,only CARG-2020 prevented tumor recurrence and provided long-term survival benefit to the tumor-bearing mice,indicating a benefit of the combined *** abscopal effects of CARG-2020 on the non-injected contralateral tumors,as well as protection from the tumor cell re-challenge,suggest immune-mediated mechanism of protection and establishment of immunological ***,CARG-2020 potently activates Th1 immune mechanisms and inhibits expression of genes related to T cell exhaustion and cancer-promoting *** ability of CARG-2020 to prevent tumor recurrence and to provide survival benefit makes it a promising candidate for its development for human cancer immunotherapy.

关键词： Virus-like vesicles Oncolytic virus IL-12 IL-17 PD-L1 T cell exhaustion Combination therapy Cancer immunotherapy

EFFECT OF MICROSTRUCTURE OF ALUMINIDE COATING ON HIGH-CYCLE FATIGUE PERFORMANCE OF COATING-SUPERALLOY SYSTEM

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Acta Metallurgica Sinica(English Letters) 1992年第2期5卷 121-127页

作者： FA N Ruilin institute of Aeronautical Materials,beijing,china Inst of Aeronautical Materials Beijing China

The high-cycle fatigue performance of different microstructures of aluminide coating- superalloy system has been studied at 900℃.The single phase coating of coarse equiaxial grain NiAI(β)has unfavorable eJfect onJatigue life of the *** fatigue life may shorten if the coating of NiAl(β)was an enrichment of coarse refractory metal grains. While an improvement can be made by dispersing numerous secondary phase particles such as *** γ′,quasi-σ-phase and others.

关键词： aluminide coating coating microstructure high temperature high cycle fatigue

STRUCTURAL REFINEMENT FOR Nd_2(Fe_(0.9)Si_(0.1))_(14) B FROM NEUTRON DIFFRACTION MEASUREMENT

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Acta Metallurgica Sinica(English Letters) 1990年第4期3卷 297-299页

作者： YANG Jilian ZHANG Baisheng JIN Lan DING Yongfan YE Chuntar institute of atomic energy,beijing,china YANG Yingchang,KONG Linshu Associate Professor,P.O.Box 275-80,beijing 102.13,china

Neutron diffraction measurements on Nd2(Fe0,Si0 ,)14B at room temperature and 77 K were performed. Data analysis using profile refinement was carried out. The results show that at room temperature Si atoms occupy preferentially 4c, 8j, and I6k2 sites, and the magnetic moments of bath Nd and Fe are parallel to C-axis. At 77 K, the site occupations remain unchanged as in room temperature, while the calculated Nd magnetic moment direction has an angular deviation of 37.8 ° from C-axis.

关键词： neutron diffraction Nd2(Fe09Si0 ,)4B magnetic moment

Target selection and transfer trajectories design for exploring asteroid mission

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Science china(Technological Sciences) 2010年第4期53卷 1150-1158页

作者： CUI PingYuan1,QIAO Dong1,CUI HuTao2 & LUAN EnJie3 1 School of Aerospace Engineering,beijing institute of Technology,beijing 100081,china 2 Harbin institute of Technology,Harbin 150001,china 3 National Defense Science and Industry Bureau,beijing 100048,china School of Aerospace Engineering Beijing Institute of Technology Beijing China Harbin institute of Technology Harbin China National Defense Science and Industry Bureau Beijing China

Technique of target selection and profiles of transfer trajectory for Chinese asteroid exploring mission are studied systemically.A complete set of approaches to selecting mission targets and designing the transfer trajectory is ***,when selecting a target for mission,some factors regarded as the scientific motivations are ***,when analyzing the accessibility of targets,instead of the classical strategy,the multiple gravity-assist strategy is *** suitable and possible targets,taking into account scientific value and technically feasible,are obtained via selection and *** designing the transfer trajectory for exploring asteroid mission,an approach to selecting gravity-assist celestial body is ***,according to the mission constraints,the trajectory profile with 2-years △V-EGA for exploring asteroid is *** analyzing the trajectory profile,unexpected result that the trajectory would pass by two main-belts asteroids is ***,the original proposal is extended to the multiple flybys *** adds the scientific return for asteroid mission.

关键词： exploring asteroid target selection multiple flybys transfer trajectory