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Split-plot designs with general minimum lower-order confounding

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Science china Mathematics 2010年第4期53卷 939-952页

作者： WEI JiaLin 1,4,YANG JianFeng 1,LI Peng 3 & ZHANG RunChu 1,2,1 school of mathematical sciences and LPMC,Nankai university,Tianjin 300071,china 2 KLAS and school of Mathematics and Statistics,Northeast normal university,Changchun 130024,china 3 school of mathematical sciences,Capital normal university,beijing 100037,china 4 school of sciences,Tianjin university of Commerce,Tianjin 300134,china 1. school of mathematical sciences and LPMC Nankai University Tianjin 300071 China4. School of Sciences Tianjin University of Commerce Tianjin 300134 China3. School of Mathematical Sciences Capital Normal University Beijing 100037 China2. KLAS and School of Mathematics and Statistics Northeast Normal University Changchun 130024 China

Split-plot designs have been widely used in industrial *** to now,most methods for choosing this kind of designs are based on the minimum aberration (MA) ***,by introducing a new pattern,called aliased effect-number pattern (AENP),Zhang et *** a general minimum lowerorder confounding (denoted by GMC for short) criterion and established a general minimum confounding (also denoted by GMC for saving notations) *** is proved that,the GMC criterion selects optimal designs in a more elaborate manner than the existing ones,and when an experimenter has a prior about the importance ordering of factors in experiments the GMC designs are better than other optimal *** this paper we extend the GMC criterion to the split-plot design case and give a GMC-FFSP criterion for ranking split-plot *** comparisons of the new criterion with the MA-MSA-FFSP criterion are given,and the optimal 32-run split-plot designs up to 14 factors under the two criteria are tabulated for comparison and application.

关键词： fractional factorial design GMC criterion minimum aberration split-plot

MAPK signal pathways in the regulation of cell proliferation in mammalian cells

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Cell Research 2002年第1期12卷 9-18页

作者： WEI ZHANG, Hui Tu LIU The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education, College of Life sciences, beijing normal university, beijing 100875. china 1The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education College of Life Sciences Beijing Normal University Beijing 100875 China 1The Key Laboratory of Cell Proliferation and Regulation Biology of Ministry of Education College of Life Sciences Beijing Normal University Beijing 100875 China

MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. At least three MAPI(families have been characterized: extracellular signal-regulated kinase (ERK), Jun kinase (JNK/SAPK) and p38 MAPK. The above effects are fulfilled by regulation of cell cycle engine and other cell proliferation related proteins. In this paper we discussed their functions and cooperation with other signal pathways in regulation of cell proliferation.

关键词： MAPK ER.K JNK/SPAK p38 cell proliferation cross-talk.

Twisted exponential sums of polynomials in one variable

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Science china Mathematics 2010年第9期53卷 2395-2404页

作者： LIU ChunLei1,& LIU WenXin2,3 1Department of Mathematics,Shanghai Jiao Tong university,Shanghai 200240,china 2Department of Fundamental Subject,Tianjin Institute of Urban Construction,Tianjin 300384,china 3school of mathematical sciences,beijing normal university,beijing 100875.china 1. Department of Mathematics Shanghai Jiao Tong University Shanghai 200240 China2. Department of Fundamental Subject Tianjin Institute of Urban Construction Tianjin 300384 China3. School of Mathematical Sciences Beijing Normal University Beijing 100875 China

The twisted T-adic exponential sums associated to a polynomial in one variable are *** explicit arithmetic polygon in terms of the highest two exponents of the polynomial is proved to be a lower bound of the Newton polygon of the C-function of the twisted T-adic exponential *** bound gives lower bounds for the Newton polygon of the L-function of twisted p-power order exponential sums.

关键词： exponential sum L-function Newton polygon

Geographical Agglomeration of Chinese Manufacturing Industries

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中国人口·资源与环境：英文版 2007年第2期5卷 3-11页

作者： Zhang Hua 1, 2, Zheng Wei3 1. Institute of Geographical sciences and Natural Resources Research, Chinese Academy of sciences, beijing 100101, china 2. Graduate school of the Chinese Academy of sciences, beijing 100039, china 3. school of Geography, beijing normal university, beijing 100875. china Institute of Geographical sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China Graduate school of the Chinese Academy of sciences Beijing 100039 China school of Geography Beijing Normal University Beijing 100875 China

Based on the plant level data from the First National Census of Basic Units, the Second National Census of Basic Units, and the First National Economic Census of china, this paper ex- amines the geographical agglomeration of Chinese manufacturing industries at a more disaggregated level both by industrial classi-fication and spatial unit analysis. Applying the agglomeration index proposed by Maurel and Sedillot, studies show that the most agglomerated industries are resource-intensive, and capital and technology intensive while industries demanding localized inputs or serving localized markets or favored by local governments are fairly dispersed. The more disaggregated industries are more spa- tially agglomerated. At the finer spatial scale, industries are more dispersed. Results indicate that within-county spillovers are stronger than nearby-county spillovers, and within-prefecture spillovers are stronger than nearby prefecture spillovers. Local- ized spillovers are still quite substantial at a range beyond that of counties. Comparing the agglomeration index of Chinese manu- facturing industries in 1996, 2001 and 2004, agglomeration seems to be a general tendency. Results also indicate that some industries have experienced remarkable changes in their levels of agglom- eration in the period 1996–2004.

关键词： industrial agglomeration manufacturing industries the MS index

Self-talk of Reflection Hologram During its construction

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Chinese Journal of Lasers 1996年第4期B5卷 334-340页

作者： LIU Dahe ZHOU Jing(Department of Physics, beijing normal university,beijing100875. china) beijing normal Univ Beijing China

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Ｓｅｌｆ－ｔａｌｋｏｆＲｅｆｌｅｃｔｉｏｎＨｏｌｏｇｒａｍＤｕｒｉｎｇｉｔｓｃｏｎｓｔｒｕｃｔｉｏｎ￥ＬＩＵＤａｈｅ；ＺＨＯＵＪｉｎｇ（ＤｅｐａｒｔｍｅｎｔｏｆＰｈｙｓｉｃｓ，ＢｅｉｊｉｎｇＮｏｒｍａｌＵｎｉｖｅｒｓｉｔｙ，Ｂｅｉｊｉｎｇ１００８７５...

关键词： reflection hologram hologram grating self-talk

Effect of Bcl-2 and caspase-3 on calcium distribution in apoptosis of HL-60 cells

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Cell Research 2000年第3期10卷 213-220页

作者： ZHANG MIN, HONG QING ZHANG, SHAO BAI XUE (Department of Biology, beijing normal university, beijing 100875. china) DepartmentofBiology BeijingNormalUniversityChina.

Apoptosis manifests in two major execution programs downstream of the death signal: the caspase pathway and organelle dysfunction. An important antiapoptosis factor, Bcl-2 protein, contributes in caspase pathway of apoptosis. Calcium, an important intracellular signal element in cells, is also observed to have changes during apoptosis, which maybe affected by Bcl-2 protein. We have previously reported that in Harringtonine (HT) induced apoptosis of HL-60 cells, there’s a change of intracellular calcium distribution, moving from cytoplast especially Golgi’s apparatus to nucleus and accumulating there with the highest concentration. We report here that caspase-3 becomes activated in HT-induced apoptosis of HL-60 cells, which can be inhibited by overexpression of Bcl-2 protein. No sign of apoptosis or intracellular calcium movement from Golgi’s apparatus to nucleus in HL-60 cells overexpressing Bcl-2 or treated with Ac-DEVD-CHO, a specific inhibitor of caspase-3. The results indicate that activated caspase-3 can promote the movement of intracellular calcium from Golgi’s apparatus to nucleus, and the process is inhibited by Ac-DEVD-CHO (inhibitor of caspase-3), and that Bcl-2 can inhibit the movement and accumulation of intracellular calcium in nucleus through its inhibition on caspase3. Calcium relocalization in apoptosis seems to be irreversible, which is different from the intracellular calcium changes caused by growth factor.

关键词： Apoptosis calcium caspase-3 bcl-2 laser scanning confocal microscopy (LSCM).

STUDY OF Ag DIFFUSION INTO Cu SINGLE CRYSTALS BY RUTHERFORD BACKSCATTERING SPECTROMETRY

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Acta Metallurgica Sinica(English Letters) 2003年第5期16卷 332-334页

作者： R.Wang 1) Key Laboratory of Beam Technology and Materials Modification, Ministry of Education, beijing 100875. china2) Institute of Low Energy Nuclear Physics, beijing normal university, beijing 100875. china3) beijing Radiation Center, beijing 100875. china Key Laboratory of Beam Technology and Materials Modification Ministry of Education Beijing 100875China Institute of Low Energy Nuclear Physics Beijing Normal University Beijing 100875 China beijing Radiation Center Beijing 100875 China

4.0Me V 7Li++ RBS was used for investigations of thermal diffusion of Ag in Cu single crystals. The annealing of samples was carried out in vacuum in the temperature range from 498K to 613K. The element depth concentration profiles transformed from RBS spectra indicate that the diffusion of Ag into Cu is a typical volume diffusion. The Arrhenius parameters corresponding to the diffusion were obtained.

关键词： Ag diffusion single crystal

Designing regional pattern for ecosystem restoration:A case study

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Science china(Technological sciences) 2006年第z1期49卷 86-97页

作者： LI Guoqiang , MA Keming, FU Bojie & LIU Shiling State Key Lab of Systems Ecology, Research Center for Eco-environmental sciences, Chinese Academy of sciences, beijing 100085, china Department of Water Environment, china Institute of Water Resources and Hydropower Research, beijing 100038, china school of Environmental sciences, beijing normal university, beijing 100875. china 1. State Key Lab of Systems Ecology Research Center for Eco-environmental Sciences Chinese Academy of Sciences Beijing 100085 China 2. Department of Water Environment China Institute of Water Resources and Hydropower Research Beijing 100038 China 3. school of Environmental sciences Beijing Normal University Beijing 100875 China

Designing regional pattern is challenging for ecosystem restoration both in theory and in practice. The present study proposed a new approach to design regional pattern for ecosystem restoration with a case in the arid valley of Upper Minjiang River, SW china. The procedures are: (1) Determine the regional pattern of main environmental factors based on the relationships between the important environmental factors and the main geographical factors generated from DEM data. (2) Overlay the maps of the main environmental factors. (3) Generate a lookup table according to the species selection rule we proposed to link the candidate restoration species to the main environmental factors.(4) Determine the regional pattern of ecosystem restoration by positioning the restoration species in the map of environmental factors according to the lookup table. The regional restoration pattern designed in this way would be applicable not only to restoring a region, but also to predicting the future landscape change.

关键词： environmental factors, GIS, restoration species, Upper Minjiang River Valley.

Refraction of light in media

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Science china(Physics,Mechanics & Astronomy) 2007年第5期50卷 591-600页

作者： ZHANG Tao Key Laboratory of Beam Technology and Material Modification of Ministry of Education, Institute of Low Energy Nuclear Physics, beijing normal university, beijing 100875. china beijing Radiation Center, beijing 100875. china Key Laboratory of Beam Technology Material Modification of Ministry of Education Institute of Low Energy Nuclear Physics Beijing Normal University Beijing 100875 China beijing Radiation Center Beijing 100875 China

The roles of the magnetic field and electric field of the light are investigated when the light is refracted in the medium. The model of the electron cloud conductor is presented. Electron cloud in a molecule is treated as a conductor and the Faraday’s Law is applied to this conductor that is in the alternating magnetic field of the light. dBM/dt of the light gives rise to an alternating induced current on the electron cloud conductor, and the light exchanges energy, i.e. the refractive energy, with the elec- tron cloud conductor. Formulas of refractive index, which is the ratio of light speed in vacuum to that in the medium, are derived with this model. These formulas are tested with several mediums and Langevin’s diamagnetic susceptibility of helium gas, and the results are in good agreement with the measured data. The anisotropy and the nonlinearity of the refractive index are explained with the theory described in this work.

关键词： refractive index, light, speed, medium, propagation