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同济大学学报（自然科学版） 1997年第1期25卷 46-49页

作者：陈建阳同济大学道路与交通工程系上海200092

以改进的微观跟车模型为基础，利用交通流稳态特性和概率统计方法得出了交通流宏观统计模型．首次在严格理论意义上使交通流微观模型和宏观统计模型得到了统一，所得的宏观统计模型在许多方面优于传统的经验回归模型．

关键词：交通流跟车模型微观宏观

Activation of ATP-sensitive potassium channels enhances DMT1mediated ferrous iron uptake in SK-N-SH cells

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Activation of ATP-sensitive potassium channels enhances DMT1...

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Xi-Xun DU,Hua-Min XU,Ning SONG,Hong JIANG,Jun-Xia XIE~* department of Physiology,Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders and state Key Disciplines:Physiology,Medical College of Qingdao university,Qingdao 266071,China

Objective Elevated iron accumulation has been reported in the substantia nigra(SN) in Parkinson’s disease(PD).Our previous study observed that increased levels of the iron importer divalent metal transporter 1(DMTl) were involved in this nigral iron accumulation and dopaminergic neurons loss in *** iron transport function of DMTl is also related to the membrane potential level,which increases with hyperpolarization of the cell membrane. Activation of ATP-sensitive potassium(K) channels,which could induce hyperpolarization of nigral dopaminergic neurons,is reported to be involved in the selective loss of these neurons in *** present study is to investigate whether activation of K channels could change the iron uptake function of *** DiBAC4(3) and calcein were used to detect membrane potential and ferrous iron *** iron concentration was measured using an inductively coupled plasma(ICP-2) *** transmembrane potential(△Ψm) and reactive oxygen species(ROS) were measured by flow cytometry using rhodamine123 and ***(1) When treated with diazoxide,a novel K channel opener,the membrane potential of SK-N-SH cells showed hyperpolarization.(2) The influx of ferrous iron and the intracellular iron levels were observed dramatically increased When the cells were co-incubated with diazoxide and ferrous iron,resulting in a decreased△Ψm and an elevated level of ROS production.(3) When treated with diazoxide,cells overexpressing SUR1 and Kir6.2 showed increased ferrous iron influx compared with the vector control,which induced a decrease in△Ψm and an increase in ROS production. Conclusion These results suggest that the activation of the K channels could enhance DMT 1-mediated ferrous iron uptake,leading to increase intracellular oxidative stress.

关键词： divalent metal transporter 1 iron ATP-sensitive potassium Parkinson’s disease

Synthesis and Magnetic Properties of Polynuclear heterometailic metal clusters

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中国化学会第五届全国结构化学学术会议

作者： Xiang-Jian Kong Yan-Ping Ren La-Sheng Long~* Rong-Bin Huang Lan-Sun Zheng state Key Laboratory of Physical Chemistry of Solid Surface and department of Chemistry,College of Chemistry and Chemical Engineering,Xiamen university,Xiamen 361005,China.

＜正＞Polynuclear heterometallic metal clusters,such as,3d-4f and 3d-5f ones,are of currently interest, due to their often exhibiting unique magnetic property and good models for the investigation on the nature of the...

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Color singletons disrupt the preview benefit of visual marking

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第一届全国脑与认知科学学术研讨会

作者： Yong Bu Qi Zhu Ke Zhou &Jia Liu state Key Laboratory of Brain and Cognitive Science Graduate School & Institute of Biophysics Chinese Academy of Science Beijing 100101 P.R. China department of Psychology Beijing university Beijing 100871 P.R. China

＜正＞If a subset of distractors is previewed before the target and the remaining distractors, search efficiency is greatly improved. The process that eliminates old items from search is called visual marking. Recent studies show that the color change of old items impairs the preview benefit, suggesting that the inhibition on the location of old items can be overridden by bottom-up visual changes. Here we ask whether bottom-up visual changes occurring at an un-marked location can disrupt visual marking as well. To answer this question, we orthogonally manipulated locations where bottom-up changes could occur by either changing

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Nonlinear Disturbance Observer Based Control for Systems with Arbitrary Disturbance Relative Degree

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第三十届中国控制会议

作者： YANG Jun~(1,2),CHEN Wen-Hua~2,LI Shihua~1,CHEN Xisong~1 1.School of Automation,Southeast university,Nanjing 210096,P.R.China 2.department of Aeronautical and Automotive Engineering,Loughborough university,LE11 3TU,UK

＜正＞The existing nonlinear disturbance observer based control（NDOBC） is only applicable for the systems whose disturbance relative degree is higher than or equal to the input relative *** disturbance attenuation problem of nonlinear systems with arbitrary disturbance relative degree is presented in this paper via a novel NDOBC approach.A systematic method is proposed to design the disturbance compensation *** is shown that the disturbance can be eliminated from the output channel in steady-state with the proposed *** input-to-state stability of the closed-loop system is also investigated rigorously by regarding the disturbance as the input of the augmented *** example of a missile demonstrates that the proposed method provides an effective way in rejecting disturbances with arbitrary disturbance relative degree.

关键词： Nonlinear Disturbance Observer Arbitrary Disturbance Relative Degree Disturbance Attenuation

Outcomes of treatment of sudden deafness using different Protocols:a retrospective analysis of 104 cases

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Journal of Otology 2010年第1期5卷 1-3页

作者： LIU Rong-rong, ZHOU Ding-rong , JI Chang-you, CHEN Ji-chuan department of Otorhinolaryngology Head and Neck Surgery, Institute of Surgery Research, Third Affiliated Hospital, Third Military Medical university of Chinese PLA ,Chongqing 400042, China department of Otorhinolaryngology Head and Neck Surgery Institute of Surgery Research Third Affiliated Hospital Third Military Medical University of Chinese PLA Chongqing 400042 China

Objective To compare different treatment protocols for sudden deafness(SD), for the purpose of identifying an appropriate approach to SD. Methods A total of 104 patients with diagnosis of sudden hearing loss treated from Jan 2006 to December 2008 were included in this study, of which 31 received the typical pharmaceutical treatment (groupⅠ), 40 received the typical pharmaceutical treatment plus polarized liquid (GroupⅡ) and 33 received the hyperbaric oxygen in addition to the treatment included in Group Ⅱ(Group Ⅲ). Results The total improvement rate (67.74%, 62.50% and 75.76% for Groups Ⅰ, Ⅱ and Ⅲ respectively) was not statistically different between the three groups (P > 0.05). Conclusion The three treatment protocols are similar when judged by the treatment outcomes in SD, neither being superior to the others. The two important factors that appear to influence treatment outcomes are the audiogram pattern and duration of hearing loss before seeking treatment. Patients with upsloping or peak-type audiograms and treated within 7 days from the onset have better prognosis than others.

关键词： Sudden deafness Therapeutic Effect Prognosis

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个人理论：教师专业成长的新视域

教育发展研究 2009年第18期29卷 80-83页

作者：杜芳芳华东师范大学教育学系博士研究生上海200062

教学实践离不开教师个人认识的参与,个人理论是决定教师行为的根本要素。个人理论内在地决定着教师教学工作的状态、质量和水平,深刻地影响着教师的专业成长。它可以为教师专业成长提供新的思维方式和理论支点,实现教师专业成长范式由"... 详细信息

教学实践离不开教师个人认识的参与,个人理论是决定教师行为的根本要素。个人理论内在地决定着教师教学工作的状态、质量和水平,深刻地影响着教师的专业成长。它可以为教师专业成长提供新的思维方式和理论支点,实现教师专业成长范式由"他律"向"自律"的转变。教师个人理论的形成,不仅可以促进教师个体教学风格的形成,更能够让教师在认识教学中提升自我。

关键词：个人理论教师专业成长

Hypothalamic Medial Preoptic Area Mediates Electroacupuncture's Normalization of Hypothalamus-Pituitary- Ovary Axis Dysfunction

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Hypothalamic Medial Preoptic Area Mediates Electroacupunctur...

第十届全国针刺麻醉针刺镇痛及针刺调整效应学术研讨会

作者： Shulan Ma,Yi Feng,Boying Chen~*. Institute of Acupuncture Research(WHO Collaborating Center for Traditional medicine),Institutes of Brain Science,department of Integrative Medicine and Neurobiology,state Key Lab of Medical Neurobiology,Shanghai Medical College, Fudan university,Shanghai,China.

We have previously reported that repeated treatments performed using electroacupuncture(EA) may normalize the dysfunction of the hypothalamus-pituitary-ovary axis(HPOA) in ovariectomized *** effect of EA treatment is seen in the hypothalamus,pituitary and peripheral tissue three levels in *** the primacy of the hypothalamic medial preoptic area(MPO) in the female reproductive system,we postulate that the MPO is the key site of action in EA treatment in female reproductive *** the first experiment,we used vaginal smear,circulating estrogen concentration and uterine morphology as indicators to validate the effects of EA on the HPOA dysfunction in ovariectomized ***,we adopted the push-pull perfusion method to detect the influence of EA on the release of gonadotropin releasing hormone(GnRH) decapeptide and neuroactive substances in the MPO of ovariectomized ***,a transfer of the MPO-perfusate from a donor ovariectomized rat that received EA treatment to the MPO of a recipient ovariectomized rat,similar EA effects could be induced in the *** results are the first to identify the MPO as a crucial site for EA treatment in normalizing reproductive dysfunction from *** may modulate the collaboration of inhibitory and stimulating factors on GnRH neurons in this region,thereby regulating the release of GnRH from the hypothalamus to facilitate the homeostasis of the *** article also provides a possibility that push-pull perfusate may be a promising method to explore the mechanism of EA in vitro.

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Clinical manifestations and cerebral angiographic findings of moyamoya disease

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Journal of pharmaceutical Analysis 2010年第2期22卷 131-134页

作者： Jian-Feng Han1,Cheng-Tai Wang2,Jian-Bo Yang1,Feng Guo1,Zheng-Yi Li11. department of Neurology,the First Affiliated Hospital,Medical School of Xi’an Jiaotong university,Xi’an 710061 2. No.2 department of Neurology,Hospital of Chinese Traditional Medicine of Baoji,Baoji 721000,China. department of Neurology First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China department of Neurology Hospital of Chinese Traditional Medicine of Baoji Baoji 721000 China

Objective To study the clinical features and angiographic findings of moyamoya disease (MMD) as well as their relationship. Methods A total of 22 MMD patients received routine digital substraction angiography (DSA). The clinical manifestations and angiographic findings were analyzed. Results Clinical manifestations varied and each patient often had multiple symptoms,including cerebral infarction in 9 patients with an average age of 23.6 (13-39 years) and cerebral hemorrhage in 7 patients with an average age of 31.2 (28-46 years). Angiographic examination found that all the diseased sides showed MMD blood vessels. The patients who received encephalo-myo-arterio-synangiosis (EMAS) had better prognosis than those without receiving the treatment. Conclusion Cerebral infarction is frequent in children and adolescents with MMD,whereas cerebral hemorrhage is common in adults. DSA is a golden criterion for diagnosing MMD. Surgical treatment,EMAS blood supply reconstruction in particular,should be prescribed.

关键词： moyamoya disease digital subtraction angiography clinical characteristic

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[1,n]σ迁移中的偶然简并性和选择定则

物理化学学报 1987年第1期3卷 4-10页

作者：陈志行张亚拉中山大学化学系

[1,n]σ迁移反应除了过渡态外整个反应过程不具对称性。同面过程的过渡态有C1对称性,异面过程的有C2对称性。n为偶数的禁阻[1,n]σ迁移中的偶然简并性曾被认为是对称性造成的。但按本文的交替性理论和简并微扰理论的探究,说明偶然简并... 详细信息

[1,n]σ迁移反应除了过渡态外整个反应过程不具对称性。同面过程的过渡态有C1对称性,异面过程的有C2对称性。n为偶数的禁阻[1,n]σ迁移中的偶然简并性曾被认为是对称性造成的。但按本文的交替性理论和简并微扰理论的探究,说明偶然简并的对称和反对称非键轨道须作线性组合成为没有对称性的成对轨道才能与前后状态保持衔按。因此,这种偶然简并性不能用对称性解释而应用交替性解释。由交替性理论容易导出[1,n]σ迁移的选择定则,而由对称性则不能导出。

关键词：选择定则交替性异面过渡态线性组合 σ迁移非键轨道简并性周环反应