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基于51系列单片机的数码相机设计与开发

计算机工程与应用 2002年第22期38卷 246-248页

作者：王博王毅暨南大学珠海学院珠海519000 西安交通大学生物医学工程研究所西安710049

文章以ATMEL89C51为数据处理及主控芯片,开发完成了EBoat100B数码相机。介绍了EBoat100B数码相机软硬件开发流程及图象处理算法,研究及开发内容涉及数码相机基本Firmware程序、数码相机与PC机的USB通讯和RGB数据传输、以及基于计算机资... 详细信息

文章以ATMEL89C51为数据处理及主控芯片,开发完成了EBoat100B数码相机。介绍了EBoat100B数码相机软硬件开发流程及图象处理算法,研究及开发内容涉及数码相机基本Firmware程序、数码相机与PC机的USB通讯和RGB数据传输、以及基于计算机资源的图象处理算法与实现。

关键词： 51系列单片机数码相机设计开发图象传感器图象输入设备计算机

On the electrical conductivity of alginate hydrogels

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Regenerative Biomaterials 2018年第5期5卷 293-301页

作者： georgia Kaklamani Diana Kazaryan James Bowen Fabrice Iacovella Spiros H.Anastasiadis George Deligeorgis institute of Electronic Structure&Laser Foundation for Research&Technology HellasP.O.Box 138571110 HeraklionCreteGreece School of Engineering and Innovation The Open UniversityMilton Keynes MK76AAUK Department of Chemistry University of CreteP.O.Box 220871003 HeraklionCreteGreece

Hydrogels have been extensively used in the field of biomedical applications,offering customizable natural,synthetic or hybrid materials,particularly relevant in the field of tissue *** the bioelectronics discipline,hydrogels are promising mainly as sensing platforms with or without encapsulated cells,showing great potential in healthcare and ***,to date there is little data in the literature which characterizes the electrical properties of tissue engineering materials which are relevant to *** this work,we present electrical characterization of alginate hydrogels,a natural polysaccharide,using a four-probe method similar to electrical impedance *** acquired conductance data show distinct frequency-dependent features that change as a function of alginate and crosslinker concentration reflecting ion kinetics inside the measured ***,the presence of NIH 3T3 fibroblasts encapsulated in the hydrogels matrix was found to alter the artificial tissue’s electrical *** method used provides valuable insight to the frequency-dependent electrical response of the resulting *** is hoped that the outcome of this research will be of use in the development of cell/electronic interfaces,possibly toward diagnostic biosensors and therapeutic bioelectronics.

关键词： alginate bioelectronics conductivity hydrogel polysaccharide resistance fibroblasts

Studying leukemia metastasis and therapy monitoring by in vivo imaging and flow cytometer

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Studying leukemia metastasis and therapy monitoring by in vi...

Theory and Method of Spatial Encoding in MR imaging

2007亚洲光电子会议保健与生物医学光学分会场

作者： Xunbin Weia, Yan Lia, Yuan Tana, Li Zhanga, Yun Chena, Guangda Liua, Tong Chenb, Zhenqin Guc, Guiying Wangd, Zenghui Zhoud, Li Wangd, Chen Wange ainstitutes of biomedical Sciences, Fudan university, 138 Yi Xue Yuan Road, Shanghai China 200032 bDepartment of Hematology, Huashan Hospital, Fudan university, Shanghai China 200040 cDepartment of Endocrinology, Xinhua Hospital, Jiaotong university, Shanghai China 200092 dShanghai institute of Optics and Fine Mechanics, Chinese Academy, 390 Qinghe Road, Shanghai China, 201800 eCollege of Medical Apparatus and Instruments, The university of Shanghai for Science and technology, 516 Jungong Road, Shanghai China 200093

Cytotoxic chemotherapy agents are the foundation of current leukemia therapy. For a large number of adult and elderly patients, however, treatment options are poor. These patients may suffer from disease that is resistant to conventional chemotherapy or may not be candidates for curative therapies because of advanced age or poor medical conditions. To control disease in these patients, new therapies must be developed that are selectively targeted to unique characteristics of leukemic cell growth and metastasis. A large body of elegant work in the field of immunology has demonstrated the mechanisms whereby leukocytes traffic to specific sites within the body. Vascular cell adhesion molecules and chemicalattractants combine to direct white blood cells to appropriate environments. Although it has been hypothesized that leukemic white blood cells home to hematopoietic organs using mechanisms similar to those of their benign leukocyte counterparts, detailed study of leukemic cell transit through bone marrow has yet to be undertaken. We develop the "in vivo microscopy" to study the mechanisms that govern leukemic cell spread through the bone marrow microenvironment in vivo in real-time confocal infrared fluorescence imaging. A recently developed "in vivo flow cytometer" and optical imaging are used to assess leukemic cell spreading and the circulation kinetics of leukemic cells. A real- time quantitative monitoring of circulating leukemic cells by the in vivo flow cytometer will be useful to assess the effectiveness of the potential therapeutic interventions.

关键词： In vivo flow cytometry in vivo fluorescence imaging cancer metastasis leukemia circulating cells chemotherapy confocal imaging

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Theory and Method of Spatial Encoding in MR Imaging

International Nuclear Medicine Consensus on the Clinical Use of Amyloid Positron Emission Tomography in Alzheimer’s Disease

CCAST“北京第二次医学影像物理和工程”国际研讨会

作者： Zhang Bida Wang Weidong Bao Shanglian Chen Guangfei(1 institute of Heavy Ion Physics Peking university Beijing 1008712 PLA General Hospital Beijing 1008533 Research center of Physical Technologies on Tumor Diagnosis and Therapy Peking university Beijing 100871)

＜正＞ In this study, through introducing a function of sensitivity profile of RF receiver coil, denoted b（x,y,z）, we scribed the imaging methods with a uniform formula. We commented on the traditional theory and imaging technique of MRI systematically and discussed fast MR imaging approaches with the parallel fashion: in traditional MRI theory, the sensitivity profile of RF receiver coil is designed as uniform. The data acquisition reduction is depended upon the power of the gradient field amplifier and its fast slew rate. But nowadays in conventional fast imaging schemes the gradient switching time and gradient field amplitude have become mayor obstacles to save the image time and improve SNR of signals. People considered spatial encoding in parallel scheme by means of RF coil array and its sensitivity distributions. New imaging methods, named spatial local Fourier transform and spatial wavelet Radio Frequency encoding, were proposed in this article. The realization of the two methods mentioned above may need the support of phased-array coil technique.

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Phenomics 2023年第4期3卷 375-389页

作者： Mei Tian Chuantao Zuo Ali Cahid Civelek Ignasi Carrio Yasuyoshi Watanabe Keon Wook Kang Koji Murakami Valentina Garibotto John OPrior Henryk Barthel Yihui Guan Jiaying Lu Rui Zhou Chentao Jin Shuang Wu Xiaohui Zhang Yan Zhong Hong Zhang Molecular imaging-Based Precision Medicine Task Group of A3(China-Japan-Korea)Foresight Program PET center Huashan HospitalFudan UniversityShanghai 200235China Human Phenome institute Fudan UniversityShanghai 201203China Department of Nuclear Medicine and PET center The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China National center for Neurological Disorders and National Clinical Research center for Aging and Medicine Huashan HospitalFudan UniversityShanghai 200040China Department of Radiology and Radiological Science Division of Nuclear Medicine and Molecular ImagingJohns Hopkins MedicineBaltimore 21287USA Department of Nuclear Medicine Hospital Sant PauAutonomous University of BarcelonaBarcelona 08025Spain Laboratory for Pathophysiological and Health Science RIKEN Center for Biosystems Dynamics ResearchKobeHyogo 650‑0047Japan Department of Nuclear Medicine Seoul National University College of MedicineSeoul 03080Korea Department of Radiology Juntendo University HospitalTokyo 113‑8431Japan Diagnostic Department University Hospitals of Geneva and NIMTlabUniversity of GenevaGeneva 1205Switzerland Department of Nuclear Medicine and Molecular imaging Lausanne University HospitalLausanne 1011Switzerland Department of Nuclear Medicine Leipzig University Medical CenterLeipzig 04103Germany Key Laboratory of Medical Molecular imaging of Zhejiang Province Hangzhou 310009China The College of biomedical Engineering and Instrument Science of Zhejiang university Hangzhou 310007China Key Laboratory for biomedical Engineering of Ministry of Education Zhejiang UniversityHangzhou 310007China 不详

Alzheimer’s disease(AD)is the main cause of dementia,with its diagnosis and management remaining *** positron emission tomography(PET)has become increasingly important in medical practice for patients with *** integrate and update previous guidelines in the field,a task group of experts of several disciplines from multiple countries was assembled,and they revised and approved the content related to the application of amyloid PET in the medical settings of cognitively impaired individuals,focusing on clinical scenarios,patient preparation,administered activities,as well as image acquisition,processing,interpretation and *** addition,expert opinions,practices,and protocols of prominent research institutions performing research on amyloid PET of dementia are *** the increasing availability of amyloid PET imaging,a complete and standard pipeline for the entire examination process is essential for clinical *** international consensus and practice guideline will help to promote proper clinical use of amyloid PET imaging in patients with AD.

关键词： Positron emission tomography(PET) Alzheimer’s disease Amyloid Brain imaging Expert consensus

Chinese guideline for the application of rectal cancer staging recognition systems based on artificial intelligence platforms (2021 edition)

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Chinese Medical Journal 2021年第11期134卷 1261-1263页

作者： Yuan Gao Yun Lu Shuai Li Yong Dai Bo Feng Fang-Hai Han Jia-Gang Han Jing-Jing He Xin-Xiang Li Guo-Le Lin Qian Liu Gui-Ying Wang Quan Wang Zhen-Ning Wang Zheng Wang Ai-Wen Wu Bin Wu Ying-Chi Yang Hong-Wei Yao Wei Zhang Jian-Ping Zhou Ai-Min Hao Zhong-Tao Zhang Colorectal Surgery Group of the Surgery Branch in the Chinese Medical Association Beihang university State Key Laboratory of Virtual Reality technology and Systems Department of General Surgery The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266555China Beihang university State Key Laboratory of Virtual Reality technology and Systems Beijing 100191China Department of General Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China Department of General Surgery Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Minimally Invasive Surgery center Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Gastrointestinal Surgery Sun Yat-sen UniversityGuangzhouGuangdong 510120China Department of General Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China institute of International Law Chinese Academy of Social SciencesBeijing 100732China Department of Colorectal Surgery Fudan University Shanghai Cancer CenterShanghai 201321China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 201321China Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China National Cancer center/National Clinical Research center for Cancer/Cancer Hospital Chinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100021China Third Hospital of Hebei Medical university ShijiazhuangHebei 050051China Department of Colon and Rectum Surgery The First Hospital of Jilin UniversityChangchunJilin 130021China Department of Surgical Oncology and General Surgery Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal TumorsMinistry of EducationThe First Affiliated Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Unit III&Ostomy Service Key laboratory of Carcinogenesis and Translational Research(Ministry of Education)Gastrointest

Development and Application of Artificial Intelligence Recognition Systems in Rectal Cancer Staging Whether for surgical treatment or for neoadjuvant chemoradiotherapy,imaging evaluation has become an important basis to perform the treatment plans.[1]The reading of imaging results requires a large number of experienced radiologists to complete,but shortages and uneven distributions of personnel cause delays and biases in imaging ***,independent research and development of automatic recognition systems of rectal cancer staging based on artificial intelligence(AI)platforms aim to partially replace practitioners’work and achieve rapid and accurate identification of rectal cancer staging.

关键词： staging artificial replace

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激光散斑衬比血流成像技术研究进展

中国激光 2018年第2期45卷 86-95页

作者：李晨曦陈文亮蒋景英范颖杨婧孜徐可欣天津大学精密仪器与光电子工程学院天津300072 天津大学精密测试技术及仪器国家重点实验室天津300072 天津市计量监督检测科学研究院天津300072

激光散斑衬比血流成像技术是在动态光散射理论及近似模型的基础上,通过分析散斑强度空间或时间起伏特性,实现活体组织中血流成像的技术。该技术具有成像面积大、速度快、分辨率高等优点,在生物医学成像研究及临床诊断中应用广泛。研究... 详细信息

激光散斑衬比血流成像技术是在动态光散射理论及近似模型的基础上,通过分析散斑强度空间或时间起伏特性,实现活体组织中血流成像的技术。该技术具有成像面积大、速度快、分辨率高等优点,在生物医学成像研究及临床诊断中应用广泛。研究人员针对激光散斑成像技术的理论模型、成像方法与应用进行了大量研究。综述了近年来激光散斑成像方法及应用方面的主要进展,并针对提高激光散斑衬比成像分辨率、对比度、成像深度和定量能力进行了讨论。同时对该方法在眼科、微循环、脑科学、皮肤科及术中监测等各领域的应用进行了总结。

关键词：医用光学光散斑衬比成像血流成像医学成像

Noise properties of multi-combination information in x-ray grating-based phase-contrast imaging

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Chinese Physics B 2020年第1期29卷 329-335页

作者： Wali Faiz Ji Li Kun Gao Zhao Wu Yao-Hu Lei Jian-Heng Huang Pei-Ping Zhu Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China university of Chinese Academy of Sciences Beijing 100049China

Grating-based x-ray phase contrast imaging has attracted increasing interest in recent decades as multimodal and laboratory source usable *** efforts have been focused on establishing a new extraction method to perform practical *** this work,noise properties of multi-combination information of newly established information extraction method,so-called angular signal radiography method,are investigated to provide guidelines for targeted and specific *** results show that how multi-combination of images can be used in targeted practical applications to obtain a high-quality image in terms of signal-to-noise *** conclusions can also hold true for upcoming targeted practical applications such as biomedical imaging,non-destructive imaging,and materials science.

关键词： grating-based phase-contrast imaging signal-to-noise ratio refraction scattering

Experimental Study of Helical CT Virtual Endosecopy of the Thoracic Aorta in the Rabbit Model of Atherosclerosis

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Experimental Study of Helical CT Virtual Endosecopy of the T...