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检索条件"作者=3 Analytical and Testing Center,school of Pharmacy,Fudan university,Shanghai,china"
313 条 记 录,以下是1-10 订阅
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Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies
Determination of S-propargyl-cysteine in rat plasma by mixed...
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第十二次全国临床药理学学术会议
作者: Yuanting Zheng~1,Hongrui Liu~(2,a),Guo Ma~1,Ping Yang~3,Lin Zhang~1,Yi Gu~4,Qing Zhu~2, Tengfei Shao~1,Peng Zhang~1,Yizhun Zhu~(2,*),Weimin Cai~1 (1 Department of Clinical pharmacy,school of pharmacy,fudan university,shanghai,china 2 Department of Pharmacology,school of pharmacy and Institute of Biomedical Sciences,fudan university,shanghai,china 3 analytical and testing center,school of pharmacy,fudan university,shanghai,china 4 Drug Metabolism and Pharmacokinetics, Hutchison Medipharma Ltd.,shanghai,china)
A simple,fast and sensitive mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method for the quantification of S-propargyl-cysteine(SPRC),a novel cardioprotective agent,has been developed and validated for prec...
来源: cnki会议 评论
Role of Apolipoprotein A-I in Protecting against Endotoxin Toxicity
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Acta Biochimica et Biophysica Sinica 2004年 第6期36卷 419-424页
作者: Juan MA, Xue-Ling LIAO, Bin LOU, and Man-Ping WU* Department of Biochemistry, school of pharmacy, fudan university, shanghai 200032, china Department of Biochemistry School of Pharmacy Fudan UniversityShanghai 200032 China
High density lipoprotein (HDL) binds lipopolysaccharide (LPS or endotoxin) and neutralizes its toxicity. We investigated the function of Apolipoprotein A-I (ApoA-I), a major apolipoprotein in HDL, in this process. Mou... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Identification and Characterization of glnA Promoter and its Corresponding Trans-regulatory Protein GlnR in the Rifamycin SV Producing Actinomycete,Amycolatopsis mediterranei U32
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Acta Biochimica et Biophysica Sinica 2006年 第12期38卷 831-843页
作者: Hao YU~(1&) Wen-Tao PENG~1 Yang LIU~1 Ting WU~2 Yu-Feng YAO~1 Ming-Xue CUI~1 Wei-Hong JIANG~1 Guo-Ping ZHAO~(1,3,4*) 1 Laboratory of Molecular Microbiology,Institute of Plant Physiology and Ecology,shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,shanghai 200032,china 2 Department of Medicinal Chemistry,school of pharmacy,fudan university,shanghai 200032,china 3 State Key Laboratory of Genetic Engineering & Department of Microbiology,school of Life Science,fudan university,shanghai 200433,china 4 Laboratory of Disease and Health Genomics,Chinese National Human Genome center at shanghai,shanghai 201203,china Laboratory of Molecular Microbiology Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200032 China Department of Medicinal Chemistry School of Pharmacy Fudan University Shanghai 200032 China State Key Laboratory of Genetic Engineering & Department of Microbiology School of Life Science Fudan University Shanghai 200433 China Laboratory of Disease and Health Genomics Chinese National Human Genome Center at Shanghai Shanghai 201203 China
The genetic requirements for the transcription of glnA,encoding the major glutaminesynthetase in a rifamycin SV-producing Amycolatopsis mediterranei strain,U32,were *** experiments showed that the promoter of U32 glnA... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
A New Stilbene Tetramer from Caragana rosea
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Chinese Chemical Letters 2003年 第10期14卷 1048-1050页
作者: Guo Xun YANG, Chang Qi HU school of pharmacy, fudan university, shanghai 200032 school of pharmacy Fudan University Shanghai 200032 China
Cararosinol A, a new stilbene tetramer, was isolated from Caragana rosea. Its structure has been established on the basis of spectroscopic evidence.
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in shanghai patients with arthropathy
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Acta Pharmacologica Sinica 2004年 第3期25卷 103-111页
作者: Wen SHI2,Yong-ming WANG,Shao-li LI3,Min YAN3,Duan Li,Bin-yan CHEN,Neng-neng CHENG Department of Pharmacology,school of pharmacy,fudan university,shanghai 200032 The center for Drug Reevaluation and 3 The center for Adverse Drug Reaction Monitoring,State Food and Drug Administration,Beijing 100061,china Department of Pharmacology School of Pharmacy Fudan University The center for Drug Reevaluation and The center for Adverse Drug Reaction Monitoring State Food and Drug Administration Beijing 100061 China
AIM: The study was to screen the possible risk factors of adverse drug reaction (ADR) induced by non-steroidal anti-inflammatory drugs (NSAIDs) in shanghai patients with arthropathy. METHODS: The subjects were ran- do... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Bacterial Type Ⅰ Glutamine Synthetase of the Rifamycin SV Producing Actinomycete,Amycolatopsis mediterranei U32,is the Only Enzyme Responsible for Glutamine Synthesis under Physiological Conditions
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Acta Biochimica et Biophysica Sinica 2006年 第12期 821-830页
作者: Wen-Tao PENG~(1&) Jin WANG~1 Ting WU~2 Jian-Qiang HUANG~1 Jui-Shen CHIAO~1 Guo-Ping ZHAO~(1,3,4) 1 Laboratory of Molecular Microbiology,Institute of Plant Physiology and Ecology,shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,shanghai 200032,china 2 Department of Medicinal Chemistry,school of pharmacy,fudan university,shanghai 200032,china 3 State Key Laboratory of Genetic Engineering/Department of Microbiology,school of Life Science,fudan university,shanghai 200433,china 4 Laboratory of Health and Disease Genomics,Chinese National Haman Genome center at shanghai,shanghai 201203,china
The structural gene for glutamine synthetase,glnA,from Amycolatopsis mediterranei U32 wascloned via screening a genomic library using the analog gene from Streptomyces *** clone wasfunctionally verified by complementi... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Distribution of nimodipine in brain following intranasal administration in rats
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Acta Pharmacologica Sinica 2004年 第4期25卷 124-129页
作者: Qi-zhi ZHANG, Xin-guo JIANG2, Chun-hua WU Department of Pharmaceutics, school ofpharmacy, fudan university, shanghai 200032, china Department of Pharmaceutics School of Pharmacy Fudan University
AIM: To determine whether nasally applied nimodipine (NM) could improve its systemic bioavailability and be transported directly from the nasal cavity to the brain. METHODS: NM was administered nasally, intravenously ... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
In vivo and in vitro chondrotoxicity of ciprofloxacin in juvenile rats
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Acta Pharmacologica Sinica 2004年 第10期 22-26页
作者: Ping LI, Neng-neng CHENG, Bin-yan CHEN, Yong-ming WANG Department of Pharmacology, school of pharmacy, fudan university, shanghai 200032, china
AIM: To study the relationship between chondrotoxicity and toxicokinetics of ciprofloxacin (CPFX). METHODS: Rats, 4-week old, were treated with CPFX 0, 400, 800, and 1200 mg/kg ig once daily on seven consecutive days.... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin
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Acta Pharmacologica Sinica 2004年 第6期25卷 105-109页
作者: Hong LI, Yun-yi ZHANG, Ya-nan SUN, Xi-yi HUANG, Yong-feng JIA, Duan LI2 Department of Pharmacology, schoolof pharmacy, fudan university, shanghai 200032, china Department of Pharmacology School of Pharmacy Fudan University Shanghai 200032 China
AIM: To establish an animal model for systemic lupus erythematosus (SLE)-like syndrome in mice. METHODS: BALB/c mice were immunized with active chromatin isolated from ConA-actived syngeneic spleno-lymphocytes. Plasma... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Effect of MePEG molecular weight and particle size on in vitro release of tumor necrosis factor-α-loaded nanoparticles
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Acta Pharmacologica Sinica 2005年 第2期26卷 242-249页
作者: Chao FANG,Bin SHI,Yuan-ying PEI~2 Department of Pharmaceutics,school of pharmacy,fudan university,shanghai 200032,china Department of Pharmaceutics School of Pharmacy Fudan University Shanghai 200032 China
Aim:To study the in vitro release of recombinant human tumor necrosis factor-alpha(rHuTNF-α)encapsulated in poly(methoxypolyethyleneglycol cyanoacry-late-co-n-hexadecyl cyanoacrylate)(PEG-PHDCA)nanoparticles,and inve... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论