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A Facile Synthetic Method for (3Z,6Z,9S,10R)-9,10-Epoxy-3,6-heneicosadiene,Sex Pheromone Component of Hyphantria Cunea (Drug)

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chinese Chemical Letters 2005年第4期16卷 468-470页

作者： Chao CHE, Zhong Ning ZHANG StateKey Laboratory IntegratedManagementofInsectsandRodents,Institute of Zoology, chinese academy of sciences. beijing 100080 Graduate School of the chinese academy of sciences. beijing 100039 StateKey Laboratory ofIntegratedManagementofInsectsandRodents Institute of ZoologyChinese Academy of Sciences Graduate School of the chinese academy of sciences

Total synthesis of (3Z, 6Z, 9S, 10R)-9, 10-epoxy-3, 6-heneicosadiene, sex pheromone component of Hyphantria cunea (Drug), was achieved using Sharpless AE kinetic resolution and alkylative epoxide rearrangement as ke... 详细信息

关键词： Sex pheromone Hyphantria cunea (Drug) Sharpless kinetic resolution asymmeric synthesis.

Modeling earthquake indexes derived from the earthquake warning system upon the planet earth

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Science china(Physics,Mechanics & Astronomy) 2010年第12期53卷 2293-2299页

作者： LI Yong National Astronomical Observatories, chinese academy of sciences. beijing 100012, china 1. National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

By studying the correlation between historical earthquake data and the distributional characteristics of parameters of solid earth tides in the earthquake epicenter, we are able to design a forecasting function of earthquake probability. We put forward a design method for the Earthquake Warning System. The model could theoretically simulate and be used to predict the probability of strong earthquakes that could occur anywhere at any time. In addition, the system could also conveniently obtain global or partial Modeling Earthquake Indexes to finally combine the precise pointing prediction and forecast of partial indexes. The literature quotes global data values, provided by NEIC, of 1544 M ≥ 6.5 earthquakes. It also gives examples of instantaneous earthquake indexes of the whole world and Taiwan Region on 1st January 2010, UT=0:00 and the average earthquake index near the Taiwan Region. According to the 10-year pointing prediction of strong earthquakes in San Francisco, the literature provides the average earthquake index on 24th June 2015 (± 15 days), in its neighborhood.

关键词： earthquake earthquake warning system astrogeodynamics index

Pre-irradiation with low-dose ^(12)C^(6+) beam significantly enhances the efficacy of AdCMV-p53 gene therapy in human non-small lung cancer

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Science china(Physics,Mechanics & Astronomy) 2007年第2期50卷 221-230页

作者： LIU Bing1,2,ZHANG Hong1,LI WenJian1,LI Qiang1,ZHOU GuangMing1,XIE Yi1,2,HAO JiFang1,MIN FengLing1,2,ZHOU QingMing1,2 & DUAN Xin1,21 Institute of Modern Physics,chinese academy of sciences.Lanzhou 730000,china 2 Graduate University of chinese academy of sciences.beijing 100039,china Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000China

The combination of ionizing radiation and gene therapy has been investigated. However, there are very few reports about the combination of heavy-ion irradiation and gene therapy. To determine if the pre-exposure to low-dose heavy ion beam enhances the suppression of AdCMV-p53 on non-small lung cancer (NSLC), the cells pre-irradiated or non-irradiated were infected with 20, 40 MOI of AdCMV-p53. Survival fraction and the relative biology effect (RBE) were determined by clonogenic assay. The results showed that the proportions of p53 positive cells in 12C6+ beam induced AdCMV-p53 infected cells were more than 90%, which were signifi-cantly more than those in γ-ray induced AdCMV-p53 infected cells. The pre-exposure to low-dose 12C6+ beam significantly prevented the G0/G1 arrest and activated G2/M checkpoints. The pre-exposure to 12C6+ beam significantly improved cell to apoptosis. RBEs for the 12C6+ + AdCMV-p53 infection groups were 30%-60%, 20%-130% and 30%-70% more than those for the 12C6+-irradiated only, AdCMV-p53 infected only, and γ-irradiation induced AdCMVp53 infected groups, respectively. The data suggested that the pre-exposure to low-dose 12C6+ beam significantly promotes exogenous p53 expression in NSLC, and the suppression of AdCMV-p53 gene therapy on NSLC.

关键词： heavy-ion beam gene therapy p53 non-small lung cancer adenoviral vector low dose

H_2CO and H110α survey toward UCHII regions

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Research in Astronomy and Astrophysics 2011年第2期11卷 156-162页

作者： Xiao-Hong Han Graduate University of chinese academy of sciences. beijing 100049, china National Astronomical Observatories / Urumqi Observatory Chinese Academy of Sciences Urumqi 830011 China Graduate University of chinese academy of sciences Beijing 100049 China

We report results of the H2CO and H110α survey toward 281 UCHII regions using the Urumqi 25m radio *** obtained 37 new H2CO detections,and H110α was simultaneously detected in eight of *** H110α was detected in another UCHII *** calculated kinematic distances of nine UCHII regions with the detected H110α and resolved the kinematic distance ambiguity for six of *** detection rate of H2CO of our observation was 13.2%,which is low compared with one of the other *** possible reason is that the sensitivity of our telescope is relatively low.

关键词： ISM: HII regions -- ISM: molecules -- radio lines: ISM

A two-round honest-verifier zero-knowledge protocol

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Science china(Information sciences. 2010年第5期53卷 954-963页

作者： LIU HanWu 1,2 & LIN DongDai 1 1 The State Key Laboratory of Information Security, Institute of Software, chinese academy of sciences. beijing 100190, china 2 Graduate University of the chinese academy of sciences. beijing 100049, china 1. The State Key Laboratory of Information Security Institute of Software Chinese Academy of Sciences Beijing 100190 China2. Graduate University of the Chinese Academy of Sciences Beijing 100049 China

Since the concept of zero-knowledge protocols was introduced, it has attracted a lot of attention and in turn showed significant effect on the development of cryptography, complexity theory and other areas. The round complexity of a zero-knowledge protocol is a very important efficiency consideration, and it is required to be as small as possible. Generally, it is desirable to have zero-knowledge protocols with constant numbers of rounds. Goldreich and Oren proved that only languages in BPP have one-round and two-round zero-knowledge protocols. Moreover, they also showed that only languages in BPP have one-round honest-verifier zero-knowledge protocols. The notion of honest-verifier zero-knowledge protocols is highly non-trivial and fascinating itself, and has many other uses. Thus, the problem as to whether there exist two-round honest-verifier zero-knowledge protocols becomes an important open problem. In this paper, we introduce a new simulation technique and present a two-round honest-verifier zero-knowledge protocol for any language in N P under a standard complexity assumption based on this technique.

关键词： proof system argument system zero-knowledge witness indistinguishability black-box one-way permutation commitment scheme zap

DNA barcoding:species delimitation in tree peonies

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Science china(Life sciences. 2009年第6期52卷 568-578页

作者： ZHANG JinMei1,2,WANG JianXiu1,2,XIA Tao1,2 & ZHOU ShiLiang1 1State Key Laboratory of Systematic and Evolutionary Botany,Institute of Botany,the chinese academy of sciences.beijing 100093,china 2Graduate School of the chinese academy of sciences.beijing 100039,china 1. State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany the Chinese Academy of Sciences Beijing 100093 China 2. Graduate School of the chinese academy of sciences Beijing 100039 China

Delimitations of species are crucial for correct and precise identification of *** "spe-cies" is more a subjective than an objective concept in taxonomic practice due to difficulties in revealing patterns of infra-or inter-specific *** phylogenetic studies at the population level solve this problem and lay a sound foundation for DNA *** this paper we exemplify the necessity of adopting a phylogenetic concept of species in DNA barcoding for tree peonies(Paeonia ***).We used 40 samples representing all known populations of rare and endangered species and several populations of widely distributed tree *** currently recognized species and major variants have been included in this *** chloroplast gene fragments,***,rps16-trnQ,trnL-F and trnS-G(a total of 5040 characters,96 variable and 69 parsimony-informative characters) and one variable and single-copy nuclear GPAT gene fragment(2093?2197 bp,279 variable and 148 parsi-mony-informative characters) were used to construct phylogenetic relationships among the *** evolutionary lineages revealed by the nuclear gene and the chloroplast genes are inconsistent with the current circumscriptions of ***,***,***,and *** based on *** inconsistencies come from(1) significant chloroplast gene divergence but little nuclear GPAT gene divergence among population systems of *** + ***,and(2) well-diverged nuclear GPAT gene but little chloroplast gene divergence between *** and *** incongruence of the phylogenies based on the chloroplast genes and the nuclear GPAT gene is probably due to the chloro-plast capture event in evolutionary history,as no reproductive barriers exist to prevent inter-specific *** also evaluated the suitability of these genes for use as DNA barcodes for tree *** variability of chloroplast genes among well-defined species or population systems of a specie

关键词： DNA barcoding evolution Paeonia phylogeny species concept

A tentative study for the prediction of the CME related geomagnetic storm intensity and its transit time

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Science china(Technological sciences. 2005年第6期48卷 648-668页

作者： ZHAO Xinhua1,2 & FENG Xueshang1,3 1. SIGMA Weather Group, Key Laboratory of Space Weather, Center for Space Science and Applied Re-search, chinese academy of sciences. beijing 100080, china 2. Graduate School of the chinese academy of sciences. beijing 100039, china 3. School of Geophysics and Geoinformation Systems, china University of Geosciences. beijing 100083, china 1. SIGMA Weather Group Key Laboratory of Space Weather Center for Space Science and Applied Research Chinese Academy of Sciences 100080 Beijing China 2. Graduate School of the chinese academy of sciences 100039 Beijing China 3. School of Geophysics and Geoinformation Systems China University of Geosciences 100083 Beijing China

Using 80 CME-ICME events during 1997.1―2002.9, based on the eruptive source locations of CMEs and solar magnetic field observation at the photosphere, a current sheet magnetic coordinate (CMC) system is established in order to study the propagation of CME and its geoeffectiveness. In context of this coordinate system, the effect of the eruptive source location and the form of heliospheric current sheet (HCS) at the eruptive time of CME on the geomagnetic storm intensity caused by CME and the CME’s transit time at the Earth is investigated in detail. Our preliminary conclusions are: 1) The geomagnetic disturbances caused by CMEs tend to have the so-called “same side-opposite side effect”, i.e. CMEs erupt from the same side of the HCS as the earth would be more likely to arrive at the earth and the geomagnetic disturbances associated with them tend to be of larger magnitude, while CMEs erupting from the opposite side would arrive at the earth with less probability and the corresponding geomagnetic disturbance magnitudes would be relatively weaker. 2) The angular separation between the earth and the HCS affect the corresponding disturbance intensity. That is, when our earth is located near the HCS, adverse space weather events occur most probably. 3) The erupting location of the CME and its nearby form of HCS will also affect its arrival time at the earth. According to these conclusions, in this context of CMC coordinate we arrive at new prediction method for estimating the geomagnetic storm intensity (Dstmin) caused by CMEs and their transit times. The application of the empirical model for 80 CME-ICME events shows that the relative error of Dst is within 30% for 59% events with Dstmin≤?50 nT, while the averaged absolute error of transit time is lower than 10 h for all events.

关键词： coronal mass ejections, current sheet magnetic coordinate system, geomagnetic storm intensity, transit time, prediction method.

A Date Recovery System launched for chronological studies in ancient china

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Science china(Physics,Mechanics & Astronomy) 2008年第1期51卷 105-110页

作者： LI Yong National Astronomical Observatories,chinese academy of sciences.beijing 100012,china 1. National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

Benefited from the performance of the Xia-Shang-Zhou Chronology Project(XSZP) in china and our new astronomical chronology method designed and processed for chinese particular 60-day-cycle Ganzhi(the heavenly stems and earthly branches)date records,we launch a Date Recovery System(DRS)for ancient china. Of high analysis function,this software can recover and convert the complete or incomplete date information originally from Ganzhi style in the historical period of china to the Gregorian Calendar System,which may have wide applications in the area of literary history,archaeology and cultural relic,etc.,and solve the Goldbach Puzzles of chinese *** an example,we give the detailed process for the sculptures on four bronze wares with the Ganzhi data and afterwards employ this software and provide their possible dates corresponding to Gregorian system.

关键词： chronology date ephemeris software

Stability of proton and maximally symmetric minimal unification model for basic forces and building blocks of matter

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Science china(Physics,Mechanics & Astronomy) 2007年第3期50卷 303-310页

作者： WU YueLiang Institute of Theoretical Physics, chinese academy of sciences. beijing 100080, china 1. Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100080 China

With the hypothesis that all independent degrees of freedom of basic building blocks should be treated equally on the same footing and correlated by a possible maximal symmetry, we arrive at a 4-dimensional space-time unification model. In this model the basic building blocks are Majorana fermions in the spinor repre- sentation of 14-dimensional quantum space-time with a gauge symmetry GM4D = SO(1,3)×SU(32)×U(1)A×SU(3)F. The model leads to new physics including mirror particles of the standard model. It enables us to issue some fundamental questions that include: why our living space-time is 4-dimensional, why parity is not con- served in our world, how the stability of proton is, what the origin of CP violation is and what the dark matter can be.

关键词： gauge symmetry space-time symmetries beyond standard model and unification