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chinese expert consensus on the clinical application of drugcoated balloon(2^(nd) Edition)

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Journal of Geriatric Cardiology 2024年第2期21卷 135-152页

作者： The Expert Writing Committee of the chinese Expert Consensus on Clinical Applications of Drug-Coated Balloon(2^(nd)Edition) Jun-Bo GE Yun-Dai CHEN 不详 Zhongshan Hospital Fudan University chinese PLA General Hospital

Percutaneous coronary interventions have progressed through the era of plain balloon dilation, bare-metal stent insertion to drug-eluting stent treatment, which has significantly reduced the acute occlusion and restenosis rates of target vessels and improved patient prognosis, making drug-eluting stents the mainstream interventional treatment for coronary artery disease. In recent years, drug-coated balloons(DCBs) have become a new treatment strategy for coronary artery disease, and the drugs used in the coating and the coating technology have progressed in the past years. Without permanent implant, a DCB delivers antiproliferative drugs rapidly and uniformly into the vessel wall via the excipient during a single balloon dilation. Many evidence suggests that DCB angioplasty is an effective measure for dealing with in-stent restenosis and de novo lesions in small coronary *** more clinical studies are published, new evidence is emerging for the use of DCB angioplasty in a wide range of coronary diseases, and the indications are expanding internationally. Based on the latest research from china and elsewhere, the Expert Writing Committee of the chinese Expert Consensus on Clinical Applications of Drug-Coated Balloon has updated the previous DCB consensus after evidence-based discussions and meetings in terms of adequate preparation of in-stent restenosis lesions, expansion of the indications for coronary de novo lesions, and precise guidance of DCB treatment by intravascular imaging and functional evaluation.

关键词： balloon drugs dealing

Pollen limitation and variation in floral longevity in gynodioecious Potentilla tanacetifolia

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Journal of Systematics and Evolution 2011年第6期49卷 539-545页

作者： 1,2Hong YAO 1Yi-Bo LUO 1(State Key Laboratory of Systematic and Evolutionary Botany,Institute of Botany,chinese academy of sciences,beijing 100093,china) 2(graduate university of the chinese academy of sciences,beijing 1.0049,china) (State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences Beijing 100093 China) (graduate university of the chinese academy of sciences Beijing 100049 China)

Pollination limitation is common in flowering plants and is thought to be a factor driving the evolution of floral *** plasticity of floral longevity to pollination may be an adaptation of plants to pollen ***,this adaptation is less critical in short-lived *** evaluate pollen limitation and the plasticity of floral longevity to pollination in Potentilla tanacetifolia,a gynodioecious herb with short-lived flowers,we analyzed its breeding system,tested sex-differential pollen limitation,and compared variations in floral display size in natural populations in Duolun County,Inner Mongolia,*** pollination experiments and pollinator exclusion treatments revealed that *** is self-compatible and non-autonomously apomictic and shows sex-differential pollen *** plasticity of floral longevity to pollination was observed;the floral duration of female plants was prolonged by approximately 3-4 hours with pollination exclusion ***,the percentage of flowers displayed on female plants during pollination exclusion treatment was significantly higher than that during natural *** natural pollination conditions,the percentage of flowers displayed on female plants was significantly higher than on hermaphrodite ***,approximately 50%of the pollen grains spread out of the anthers of hermaphrodite flowers within 2 h of anthesis;the number of pollen grains adhering to the stigmas of hermaphrodite flowers was significantly higher than that adhering to female flowers when flowers shed their *** results indicate that variation in floral longevity may be an adaptive strategy to pollination conditions for gynodioecious ***.

关键词： floral longevity gynodioecy plasticity pollen limitation Potentilla tanacetifolia.

Comparative study of pollination biology of two closely related alpine Primula species,namely Primula beesiana and *** (Primulaceae)

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Journal of Systematics and Evolution 2010年第2期48卷 109-117页

作者： 1,2Zhi-Kun WU 1Chang-Qin ZHANG 1(Kunming Institute of Botany,chinese academy of sciences,Kunming 650204,china) 2(graduate School of chinese academy of sciences,beijing 1.0049,china) (Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China) (graduate School of chinese academy of sciences Beijing 100049 China)

The comparative pollination biology of a population of Primula beesiana,a population of ***,and an overlapping population of these two species in Yulong Shan,Yunnan Province,china,was studied in 2004 and *** results indicate that both *** and *** are typical heterostylous and obligate outcrossing species;the main pollinators of the two species were bees and *** the sites of all three populations,the main pollinating visitors of the two species showed preference for one of the two species,resulting in the ethological isolation of the two species by the *** ethological isolation contributes to the reproductive isolation of the two species,which supports the hypothesis that *** and *** are two distinct *** reproductive isolation of the two species (ethological isolation) is probably an important mechanism in maintaining species boundaries in the genus and has contributed to the species diversification of Primula in the *** addition,gene exchanges between *** and *** has occurred to some extent in the overlapping population,but whether natural hybridization has contributed to species diversification in Primula remains to be determined.

关键词： pollination biology Primula beesiana Primula bulleyana reproductive isolation

Simulation of aerodynamic performance affected by vortex generators on blunt trailing-edge airfoils

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Science china(Technological sciences) 2010年第1期53卷 1-7页

作者： YANG Ke1,2,ZHANG Lei1,3 & XU JianZhong1,2 1 Institute of Engineering Thermophysics,chinese academy of sciences,beijing 100190,china 2 Key Laboratory of Wind Energy Utilization,chinese academy of sciences,beijing 100190,china 3 graduate School of chinese academy of sciences,beijing 100190,china Institute of Engineering Thermophysics Chinese Academy of Sciences Beijing China Key Laboratory of Wind Energy Utilization Chinese Academy of Sciences Beijing China graduate School of chinese academy of sciences Beijing China

An investigation was carried out by numerical simulation on a wind turbine airfoil and a blunt trailing-edge airfoil with and without vortex generators (VGs), and the performance of the airfoils was analyzed. By the simulation of airfoil DU 91-W2-250 it was verified that the numerical method and model were credible. Based on this airfoil, a new one with a blunt trailing edge of 6% chord was blended by symmetrically adding thickness, and its characteristics curves were obtained through computing at key angles of attack. Additionally, the pressure distribution on blended airfoil was analyzed by comparing to the airfoil without blend. The interaction of streamwise vortices induced by VGs with trailing vortex or separation vortex was considered, followed by the uncovery of how VGs can suppress the boundary layer separation.

关键词： vortex generators airfoil blunt trailing-edge

Molecular identification of species in Prunus sect. Persica (Rosaceae), with emphasis on evaluation of candidate barcodes for plants

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Journal of Systematics and Evolution 2011年第2期49卷 138-145页

作者： 1,2 Xu QUAN 1 Shi-Liang ZHOU 1 (State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, chinese academy of sciences, beijing 100093, china) 2 (graduate School of the chinese academy of sciences, beijing 1.0049, china) (State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences Beijing 100093 China) (graduate School of the chinese academy of sciences Beijing 100049 China)

Species of Prunus L. sect. Persica are not only important fruit trees, but also popular ornamental and medicinal plants. Correct identification of seedlings, barks, or fruit kernels is sometimes required, but no reliable morphological characters are available. Nowadays, the technique of DNA barcoding has the potential to meet such requirements. In this study, we evaluated the suitability of 11 DNA loci (atpB-rbcL, trnH-psbA, trnL-F, trnS-G, atpF-H, rbcL, matK, rpoB, rpoC1, nad1, and internal transcribed spacer [ITS]) as candidate DNA barcodes for peaches, using samples from 38 populations, covering all the species in sect. Persica. On the whole, the primers worked well in this group and sequencing difficulties were met only in the case of ITS locus. Five loci (rbcL, matK, rpoB, rpoC, and nad1) have very low variation rates, whereas atpB-rbcL, atpF-H, trnH-psbA, trnL-F and trnS-G show more variability. The most variable loci, atpB-rbcL and trnH-psbA, can distinguish three of the five species. Two two-locus combinations, atpB-rbcL+trnL-F and atpB-rbcL+atpF-H, can resolve all five species. We also find that identification powers of the loci are method-dependent. The NeighborNet method shows higher species identification power than maximum parsimony, neighbor joining, and unweighted pair group method with arithmetic mean methods.

关键词： atpB-rbcL DNA barcode Prunus sect. Persica trnL-F.

Twistor bundle theory and its application

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Science china Mathematics 2004年第4期47卷 605-616页

作者： PENG Chia-Kuei & TANG ZizhouDepartment of Mathematics, graduate School of chinese academy of sciences, beijing 100039, china Department of Mathematical sciences, Tsinghua university, beijing 100084, china Department of Mathematics Graduate School of Chinese Academy of Sciences Beijing China Department of Mathematical sciences Tsinghua University Beijing China

Over an oriented even dimensional Riemannian manifold(M 2m ,ds2 ), in terms of the Levi-Civita connection form Ω and the canonical form Θ on the bundle of positive orthonormal frames, we give a detailed description of the twistor bundle Гm = SO(2m)/U(m)? J +(@#@ M,ds2 ) →M. The integrability on an almost complex structureJ compatible with the metric and the orientation, is shown to be equivalent to the fact that the corresponding cross section of the twistor bundle is holomorphic with respect toJ and the canonical almost complex structureJ 1 onJ +(M,ds2 ), by using moving frame theory. Moreover, for various metrics and a fixed orientation onM, a canonical bundle isomorphism is established. As a consequence, we generalize a celebrated theorem of LeBrun.

关键词： almost complex structure, integrability, twistor bundle.

Cloning,expression and characterization of a nucleoside diphosphate kinase (NDPK) gene from tobacco

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Progress in Natural Science:Materials International 2007年第8期17卷 906-912页

作者： Zhou Qiyun~(1,2**) Xie Zongming~(1**) Zhang Zhigang~1 Cao Yangrong~1 Zhang jinsong~(1***) Chen Shouyi~(1***) (1.National Key Laboratory of Plant Genomics,Institute of Genetics and Developmental Biology,chinese academy of sciences,beijing100101,china 2.graduate university of chinese academy of sciences,beijing 100039,china) National Key Laboratory of Plant Genomics Institute of Genetics and Developmental Biology Chinese Acad. of Sci. Beijing 100101 China graduate university Chinese Acad. of Sci. Beijing 100039 China

Nucleoside diphosphate kinase (NDPK) is a housekeeping enzyme that maintains the intracellular levels of all (d)NTPs used in biosynthesis except *** we report that a full-length cDNA encoding nucleoside diphosphate kinase (NDPK) was cloned us- ing yeast two-hybrid approach.A tobacco NDPK gene was obtained and designated as ***1 is 704 bp in length and en- codes a putative 16.2 kD protein of 148 amino *** analysis showed that NtNDPK1 is highly homologous to other plant NDPK genes and identified as type I (NDPK1).RNA-gel blot analysis showed that there was no significant difference of NtNDPK1 ex- pression in roots,stems,leaves and *** expression of NtNDPK1 was induced by ABA and PEG and repressed by NaCl,but not significantly affected by Paraquat,wounding and low temperature (4℃) treatments,indicating that NtNDPK1 may play a certain role in response to abiotic *** vitro phosphorylation assay demonstrated that NtNDPK1 had autophosphoryLation activity.

关键词： abiotic stress autophosphorylation activity NtNDPK1 tobacco yeast two-hybrid

Polynomial regression calculation of the Earth's position based on millisecond pulsar timing

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Research in Astronomy and Astrophysics 2012年第2期12卷 219-234页

作者： Feng Tian 1,2,Zheng-Hong Tang 1,Qing-Zeng Yan 1,2 and Yong Yu 11 Shanghai Astronomical Observatory,chinese academy of sciences,Shanghai 200030,china 2 graduate university of chinese academy of sciences,beijing 1.0049,china Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China graduate university of chinese academy of sciences Beijing 100049 China

Prior to achieving high precision navigation of a spacecraft using X-ray observations, a pulsar rotation model must be built and analysis of the precise posi- tion of the Earth should be performed using ground pulsar timing observations. We can simulate time-of-arrival ground observation data close to actual observed values before using pulsar timing observation data. Considering the correlation between the Earth＇s position and its short arc section of an orbit, we use polynomial regression to build the correlation. Regression coefficients can be calculated using the least square method, and a coordinate component series can also be obtained; that is, we can calcu- late Earth＇s position in the Barycentric Celestial Reference System according to pulse arrival time data and a precise pulsar rotation model. In order to set appropriate param- eters before the actual timing observations for Earth positioning, we can calculate the influence of the spatial distribution of pulsars on errors in the positioning result and the influence of error source variation on positioning by simulation. It is significant that the threshold values of the observation and systematic errors can be established before an actual observation occurs; namely, we can determine the observation mode with small errors and reject the observed data with big errors, thus improving the positioning result.

关键词： autonomous positioning - millisecond pulsar - pulsar timing - re-gression analysis

A new approach of cascade utilization of the chemical energy of fuel

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Progress in Natural Science:Materials International 2006年第5期16卷 518-523页

作者： HAN Wei, JIN Hongguang and LIN Rumou ( Institute of Engineering Thermophysics, chinese academy of sciences, beijing 100080, china graduate School of the chinese academy of sciences, beijing 100080, china) Institute of Engineering Thermophysics Chinese Academy of Sciences Beijing 100080 China graduate School of the chinese academy of sciences Beijing 100080 China

The indirect release of chemical energy of fuel is investigated, and a new mechanism is proposed to identify the cascade utilization of chemical energy of fuel more clearly. Based on the concept of energy level, the internal phenomenon of the indirect chemical energy release is disclosed, and the equations of energy level describing the utilization of chemical energy and thermal energy during the indirect chemical energy release process are obtained. From theoretical analysis, we find that the superiority of the indirect chemical energy release of fuel comes from the cascade utilization of the fuel's chemical energy. Moreover, the cascade utilization of chemical energy is verified by the investigation of CRGT (chemically recuperated gas turbine). As a result, the thermal exergy obtained from the chemical energy release of fuel increases by 2 % -3 % . The results obtained here may help a deeper understanding of indirect chemical energy release of fuel and provide a theoretical basis for the synthesis of innovative energy systems.

关键词： chemically recuperated gas turbine methane/steam reforming chemical energy level cascade utilization.