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Dynamics of morphological changes for mitochondrial fission and fusion

Science china(Physics,Mechanics & Astronomy) 2010年第4期53卷 680-689页

作者： WANG ShiQi 1,2,4 , FU ChangLiang 1,2 , ZHANG Yan 1,2 , CHEN Quan 3 & LONG Mian 1,2 1 Key Laboratory of Microgravity (National Microgravity Laboratory), beijing 100190, china 2 Center for Biomechanics and Bioengineering, institute of Mechanics, chinese academy of sciences, beijing 100190, china 3 State Key Laboratory of Biomembrane and Membrane Biotechnology, institute of Zoology, chinese academy of sciences, beijing 100101, china 4 institute of Vertebrate Paleontology and Paleoanthropology, chinese academy of sciences, beijing 100044, china 1. Key Laboratory of Microgravity (National Microgravity Laboratory) Beijing 100190 China2. Center for Biomechanics and Bioengineering Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China4. Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Beijing 100044 China3. State Key Laboratory of Biomembrane and Membrane Biotechnology Institute of Zoology Chinese Academy of Sciences Beijing 100101 China

Mitochondria experience continuous fusion and fission in a living cell, but their dynamics remains poorly quantified. Here a theoretical model was developed, upon a simplified population balance equation (PBE), to predict the morphological changes induced by mitochondrial fission and fusion. Assuming that both fission and fusion events are statistically independent, the survival probability of mitochondria staying in the fission or fusion state was formulated as an exponentially-decayed function with time, which depended on the time-dependent distribution of the mitochondrial volume and the fission and fusion rates. Parametric analysis was done for two typical volume distributions. One was Gamma distribution and the other was Gaussian distribution, derived from the measurements of volume distribution for individual mitochondria in a living cell and purified mitochondria in vitro. The predictions indicated that the survival probability strongly depended on morphological changes of individual mitochondria and was inversely correlated to the fission and fusion rates. This work provided a new insight into quantifying the mitochondrial dynamics via monitoring the evolution of the mitochondrial volume.

关键词： mitochondria morphology fission fusion dynamics modeling

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The solid lubricating material experiment device for Shenzhou-7 Spaceship

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Science china(Technological sciences) 2010年第9期53卷 2521-2527页

作者： WANG Ke1,2,REN WeiJia1,WANG ShiDa1 & WENG LiJun3 1 academy of Opto-Electronics,chinese academy of sciences,beijing 100190,china 2 Graduate University of chinese academy of sciences,beijing 100049,china 3 Lanzhou institute of Chemical Physics,chinese academy of sciences,Lanzhou 730000,china 1. academy of Opto-Electronics Chinese Academy of Sciences Beijing 100190 China2. Graduate University of Chinese Academy of Sciences Beijing 100049 China3. Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 China

A solid lubricating material exposure experiment in space is one of the missions during the seventh manned spaceflight of china,and the key is to develop a device which can be fixed reliably outside of the orbital module and can be fetched conveniently by an astronaut during space *** solid lubricating material experiment device needs to be locked reliably in a vibrating and impacting environment during the launch phase,and should meet the requirement that it can be unlocked and fetched reliably by the astronaut wearing an extravehicular spacesuit via simple operations in orbit in an environment of high and low *** for the device we developed,the environmental characteristic of the mission was analyzed,the mechanical analysis and thermal analysis were carried out,and then a mechanism with functions of mechanical locking,structural self-locking and manual unlocking was *** device was verified by a sequence of experiments and was fetched by the astronaut during the flight of the Shenzhou-7 Spaceship.

关键词： manned spaceflight exposure experiment mechanism unlock

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A two-round honest-verifier zero-knowledge protocol

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Science china(Information sciences) 2010年第5期53卷 954-963页

作者： LIU HanWu 1,2 & LIN DongDai 1 1 The State Key Laboratory of Information Security, institute of Software, chinese academy of sciences, beijing 100190, china 2 Graduate University of the chinese academy of sciences, beijing 100049, china 1. The State Key Laboratory of Information Security Institute of Software Chinese Academy of Sciences Beijing 100190 China2. Graduate University of the Chinese Academy of Sciences Beijing 100049 China

Since the concept of zero-knowledge protocols was introduced, it has attracted a lot of attention and in turn showed significant effect on the development of cryptography, complexity theory and other areas. The round complexity of a zero-knowledge protocol is a very important efficiency consideration, and it is required to be as small as possible. Generally, it is desirable to have zero-knowledge protocols with constant numbers of rounds. Goldreich and Oren proved that only languages in BPP have one-round and two-round zero-knowledge protocols. Moreover, they also showed that only languages in BPP have one-round honest-verifier zero-knowledge protocols. The notion of honest-verifier zero-knowledge protocols is highly non-trivial and fascinating itself, and has many other uses. Thus, the problem as to whether there exist two-round honest-verifier zero-knowledge protocols becomes an important open problem. In this paper, we introduce a new simulation technique and present a two-round honest-verifier zero-knowledge protocol for any language in N P under a standard complexity assumption based on this technique.

关键词： proof system argument system zero-knowledge witness indistinguishability black-box one-way permutation commitment scheme zap

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CMQV+:An authenticated key exchange protocol from CMQV

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Science china(Information sciences) 2012年第7期55卷 1666-1674页

作者： LI Hui 1,2 & WU ChuanKun 1 1 State Key Laboratory of Information Security,institute of Software,chinese academy of sciences,beijing 100190,china 2 Graduate University of chinese academy of sciences,beijing 100049,china 1. State Key Laboratory of Information Security Institute of Software Chinese Academy of Sciences Beijing 100190 China2. Graduate University of Chinese Academy of Sciences Beijing 100049 China

Ustaoglu presents a secure and efficient key exchange protocol named CMQV,based on the design rationales of HMQV and *** with the latter two protocols,on one hand,CMQV achieves high performance of HMQV,and on the other,it is proven secure in eCK model as NAXOS ***,CMQV enjoys the security proof under gap Diffie-Hellman assumption as indicated by its *** this paper,we propose a variant of CMQV,called CMQV+,which is proven secure under a weaker assumption (*** Diffie-Hellman assumption) in eCK model with random oracles while maintaining the high-performance feature of CMQV as much as possible.

关键词： key exchange eCK model trapdoor-test technique provable security CDH assumption

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Direct numerical simulation of shock/turbulent boundary layer interaction in a supersonic compression ramp

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Science china(Physics,Mechanics & Astronomy) 2010年第9期53卷 1651-1658页

作者： LI XinLiang1,FU DeXun2,MA YanWen2 & LIANG Xian1 1 Key Laboratory of High Temperature Gas Dynamics,institute of Mechanics,chinese academy of sciences,beijing 100190,china 2 The State Key Laboratory of Nonlinear Mechanics,institute of Mechanics,chinese academy of sciences,beijing 100190,china 1. Key Laboratory of High Temperature Gas Dynamics Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China2. The State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China

A direct numerical simulation of the shock/turbulent boundary layer interaction flow in a supersonic 24-degree compression ramp is conducted with the free stream Mach number *** blow-and-suction disturbance in the upstream wall boundary is used to trigger the *** the mean wall pressure and the velocity profiles agree with those of the experimental data,which validates the *** turbulent kinetic energy budget in the separation region is *** show that the turbulent production term increases fast in the separation region,while the turbulent dissipation term reaches its peak in the near-wall *** turbulent transport term contributes to the balance of the turbulent conduction and turbulent *** on the analysis of instantaneous pressure in the downstream region of the mean shock and that in the separation bubble,the authors suggest that the low frequency oscillation of the shock is not caused by the upstream turbulent disturbance,but rather the instability of separation bubble.

关键词： compression ramp shock/turbulent boundary layer interaction direct numerical simulation shock oscillation

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Poisson kernel and Cauchy formula of a non-symmetric transitive domain

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Science china Mathematics 2010年第7期53卷 1678-1683页

作者： LU Qi-Keng institute of Mathematics, academy of Mathematics and System Science, chinese academy of sciences, beijing 100190, china 1. institute of Mathematics Academy of Mathematics and System Science Chinese Academy of Sciences Beijing 100190 China

In 1965, Lu Yu-Qian discovered that the Poisson kernel of the homogenous domain S m,p,q={Z∈Cm×m, Z1∈Cm×p,Z2 ∈Cq×m|2i1( Z-Z+)-Z1Z1′-Z2′Z2>0} does not satisfy the Laplace-Beltrami equation associated with the Bergman metric when S m,p,q is not symmetric. However the map T0:Z→Z, Z1→Z1 , Z2→Z2 transforms S m,p,q into a domain S I (m, m + p + q) which can be mapped by the Cayley transformation into the classical domains R I (m, m + p + q). The pull back of the Bergman metric of R I (m, m + p + q) to S m,p,q is a Riemann metric ds 2 which is not a Khler metric and even not a Hermitian metric in general. It is proved that the Laplace-Beltrami operator associated with the metric ds 2 when it acts on the Poisson kernel of S m,p,q equals 0. Consequently, the Cauchy formula of S m,p,q can be obtained from the Poisson formula.

关键词： Poisson kernel Cauchy formula

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SYNTHESIS AND CHARACTERIZATION OF NEW STABILIZERS WITH OPTIMAL MOLECULAR WEIGHT

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chinese Journal of Polymer Science 2001年第4期19卷 341-350页

作者： Jiang-qing Pan institute of Chemistry chinese academy of sciences, beijing 100080 china chinese Acad Sci Inst Chem Beijing 100080 Peoples R China

Over 2 x 10(8) tons of polymers are produced every year, and a large portion of polymers faces the degradation problem. There are many effective methods to protect polymers against degradation and the addition of stabilizers to polymer remains the most convenient and effective way of enhancing polymer life and performance. In this article, a series of effective stabilizers with optimal molecular weight (MW), including common, monomeric and polymeric stabilizers (antioxidant and light stabilizer) were synthesized using isocyanation, controlled isocyanation, hydrosilylation, epoxide addition, macroreaction of stabilizing functional compounds and polymerization of monomeric stabilizers. The structure and performance of these new stabilizers were characterized by using IR, NMR, MS, UV-spectra, XPS and elemental analysis. The current development of stabilizer synthesis was also reviewed.

关键词： preparation of stabilizer antioxidant hindered amine light stabilizer isocyanation hydrosilylation

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A mixed method for measuring low-frequency acoustic properties of macromolecular materials

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Science china(Physics,Mechanics & Astronomy) 2006年第6期49卷 729-739页

作者： LIU Hongwei1,YAO Lei1,3,ZHAO Hong1,3,ZHANG Jichuan2,3 & XUE Zhaohong2 1. National Key Laboratory of acoustics,institute of acoustics,chinese academy of sciences,beijing 100080,china 2. institute of Chemistry,chinese academy of sciences,beijing 100080,china 3. Graduate University of chinese academy of sciences,beijing 100049,china National Key Laboratory of acoustics Institute of Acoustics Chinese Academy of Sciences Beijing 100080 China institute of Chemistry Chinese Academy of Sciences Beijing 100080 China Graduate University of chinese academy of sciences Beijing 100049 China

A mixed method for measuring low-frequency acoustic properties of macro-molecular materials is presented. The dynamic mechanical parameters of materials are first measured by using Dynamic Mechanical Thermal Apparatus(DMTA) at low frequen-cies,usually less than 100 Hz; then based on the Principles of Time-Temperature Super-position (TTS),these parameters are extended to the frequency range that acousticians are concerned about,usually from hundreds to thousands of hertz; finally the extended dynamic mechanical parameters are transformed into acoustic parameters with the help of acoustic measurement and inverse analysis. To test the feasibility and accuracy,we measure a kind of rubber sample in DMTA and acquire the basic acoustic parameters of the sample by using this method. While applying the basic parameters to calculating characteristics of the sample in acoustic pipe,a reasonable agreement of sound absorp-tion coefficients is obtained between the calculations and measurements in the acoustic pipe.

关键词： low-frequency acoustic properties,dynamic mechanical properties,Principles of Time-Temperature Superposition,acoustic pipe,sound absorption coefficient.

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Research of the Gas-solid Flow Character Based on the DEM Method

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Journal of Thermal Science 2011年第6期20卷 521-526页

作者： Xueyao Wang and Yunhan Xiao Research Center for Clean Energy and Power,chinese academy of sciences Key Laboratory of Advanced Energy and Power,chinese academy of sciences (institute of Engineering Thermophysics),beijing,100190,china Research Center for Clean Energy and Power Chinese Academy of Sciences Beijing China Key Laboratory of Advanced Energy and Power Chinese Academy of Sciences (Institute of Engineering Thermophysics) Beijing China

Numerical simulation of gas-solid flow behaviors in a rectangular fluidized bed is carried out three dimensionally by the discrete element method (DEM).Euler method and Lagrange method are employed to deal with the gas phase and solid phase *** collided force among particles,striking force between particle and wall,drag force,gravity,Magnus lift force and Saffman lift force are considered when establishing the mathematic ***-sphere model is used to describe the collision of *** addition,the Euler method is also used for modeling the solid phase to compare with the results of *** flow patterns,particle mean velocities,particles' diffusion and pressure drop of the bed under typical operating conditions are *** results show that the DEM method can describe the detailed information among particles,while the Euler-Euler method cannot capture the micro-scale *** matter which method is used,the diffusion of particles increases with the increase of gas *** the gathering and crushing of particles cannot be simulated,so the energy loss of particles' collision cannot be calculated and the diffusion by using the Euler-Euler method is *** addition,it is shown by DEM method,with strengthening of the carrying capacity,more and more particles can be schlepped upward and the dense suspension upflow pattern can be ***,the results given by the Euler-Euler method are not consistent with the real situation.

关键词： DEM gas-solid flow numerical simulation

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A NEW STABILIZED FINITE ELEMENT METHOD FOR SOLVING THE ADVECTION-DIFFUSION EQUATIONS

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Journal of Computational Mathematics 2002年第1期20卷 57-64页

作者： Huo-yuan Duan (institute of Mathematics, academy of Mathematics and System sciences, chinese academy of sciences, beijing 100080, china) institute of Mathematics Academy of Mathematics and System Sciences Chinese Academy of Sciences 北京 100080

Focuses on a study on the development of a stabilized finite element method for solving the advection-diffusion equations with a zero Dirichlet boundary condition. Problem formulation; Error analysis.

关键词： advection-diffusion equation stabilized finite element method

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