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一种改进的基于DP原理的分段轮廓采样算法

计算机工程与应用 2004年第21期40卷 21-24页

作者：夏仁波刘伟军王越超中国科学院沈阳自动化研究所先进制造技术实验室

首先详细介绍了由Douglas和Peucker提出的DP轮廓采样算法。然后采用分割与合并相结合的思想,提出了基于DP算法的分段轮廓采样算法,并从数学上证明了该算法在运行时间上比原DP算法快了η倍,η取值为logn/MnηM。最后,针对医学图像,文章... 详细信息

首先详细介绍了由Douglas和Peucker提出的DP轮廓采样算法。然后采用分割与合并相结合的思想,提出了基于DP算法的分段轮廓采样算法,并从数学上证明了该算法在运行时间上比原DP算法快了η倍,η取值为logn/MnηM。最后,针对医学图像,文章通过实验比较了两种算法的运行时间,结果表明该文提出的算法更快速,也易于编程。

关键词： DP算法轮廓采样分段采样医学图像处理

The Study on The Immune Response Induced by Expressing Recombinant Plasmid of Dengue Virus Type 2.NS3 Protein

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Wuhan university Journal of Natural sciences 2000年第2期5卷 245-248页

作者： LI Xiang qun 1, MAO Lin 1 , YAN Zhan qiu 1 JIANG Li feng 2. YAN Hui jun 2. GUO Hui yu 2.. Deptartement of Clinical Virology, Institute of Viral Research,Hubei Medical university, Wuhan. 430071 2. Deptartement of Microbiology, Sun yat Sen Uni Department of Clinical Virology Institute of Viral Research Hubei Medical University Wuhan. 430071 China

The PSV?NS3, an expressing recombinant plasmid of dengue virus type 2.NS3 protein, was injected directly into the quadriceps of Balb/C mice to explore whether it could inducing immune response. The splenic T cell subsets of two groups was analysed by flow cytometry. It was found that the percentage of CD4+ and CD8+ T cells of experimental group were significantly higher than those of the control group. The titer of IgG antibody was as high as 1∶5 12. in experimental group, but it couldn’t be detected in control group by ELISA. The western blot further proved that the IgG antibody was specific for NS3 protein. Those results Suggested that inoculation Balb/C mice with PSV?NS3 could inducing immune response, and the NS3 protein might be used as the candidate protein of DNA vaccine of dengue virus.

关键词： Key words Dengue Virus Type 2 NS3 Protein DNA Vaccine Immune Response

Solid state synthesis and structure of two novel polyoxometalates [(n-Bu)_4N]_4[M_6o_(19)][Ag_2._4](M=Mo,W)

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chinese Journal of Chemistry 1996年第2期14卷 123-130页

作者： HOU,Hong-Wei XIN,Xin-QuanState Key Laboratory of Coordination Chemistry,Department of Chemistry,Nanjing university,Nanjing,Jiangsu 2.0093,chinaYU,Kai-BeiChengdu Center of Analysis and Determination,{2. academy of sciences,Chengdu,Sic/man 610041,chinaWANG,Zhe-Min LIU,Shi-Xiong HUANG,Jin-LingDepartment of Chemistry,Fuzhou university,Fuihou,Fujian 350002.china State Key Laboratory of Coordination Chemistry Department of Chemistry Nanjing University Nanjing Jiangsu 210093 China

The reaction of [NH4]2.MO2.2.,AgI and (n-Bu)4NBr in solid state produced the polyoxometalates [(n-Bu)4N]4[M6O19][Ag2.4] (1,M=Mo;2.M=W) which were structurally *** crystals of 1 and 2.are isomorphous,monoclinic,space group P2.1/c.1,a=1.662.(2.,6=1.6699(3),c=1.72.7(2. nm,(8=98.2.(1)°,V =4.72.(1) nm3,Z=2.R=0.040,Rw=0.037;2.a= 1.6636(3),6=1.6733(3),c=1.7190(3) nm,β=98.2.(1)°,V=4.736(1) nm3,Z=2.R=0.038,Rw=*** results of the structure determination showed that the two compounds had the same structures whose skeletons are composed of [Ag2.4]2.and [M6O19]2.The difference of them and heteropolymetalate compounds synthesized in solution is that the title compounds contain cluster ion,heteropolymetalate and organic cations,while the latter is only composed of heteropolymetalate and organic cations.

关键词： Solid state synthesis coordination compound structure

Tetramethylpyrazine suppresses HIF-1α,TNF-α,and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats

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Acta Pharmacologica Sinica 2007年第3期28卷 327-333页

作者： Yi CHANG~(2.3) George HSIAO~4 Seu-hwa CHEN~4 Yi-cheng CHEN~4 Jiing-han LIN~4 Kuang-hung LIN~4 Duen-suey CHOU~4 Joen-rong SHEU~(4,5)2.Department of Anesthesiology,Shin Kong Wu Ho-Su Memorial Hospital,Taipei 110,Taiwan,china 3 School of Medicine,Fu-Jen Catholic university,Taipei,110,Taiwan,china 4 graduate Institute of Medical sciences,Taipei Medical university,Tuipei 110,Taiwan,china Department of Anesthesiology Shin Kong Wu Ho-Su Memorial Hospital Taipei 110 Taiwan China School of Medicine Fu-Jen Catholic University Taipei 110 Taiwan China graduate Institute of Medical sciences Taipei Medical University Taipei 110 Taiwan China

Aim:To examine the detailed mechanisms underlying the inhibitory effect oftetramethylpyrazine(TMPZ)in inflammatory and apoptotic responses inducedby middle cerebral artery occlusion(MCAO)in ***:MCAO-inducedfocal cerebral ischemia in rats was used in this *** hypoxia-induciblefactor-1α(HIF-1α),activation of caspase-3,and TNF-αmRNA transcription inischemic regions were detected by immunoblotting and RT-PCR,***-oxidative activity was investigated using a thiobarbituric acid-reactive sub-stance(TBARS)test in rat brain homogenate ***:We showedthe statistical results of the infarct areas of solvent-and TMPZ(2. mg/kg)-treatedgroups at various distances from the frontal pole in MCAO-induced focal cerebralischemia in *** with TMPZ(2. mg/kg)markedly reduced the infarctarea in all regions,especially in the third to fifth ***-induced focalcerebral ischemia was associated with increases in HIF-lαand the activation ofcaspase-3,as well as TNF-αtranscription in ischemic *** expressionswere markedly inhibited by treatment with TMPZ(2. mg/kg).However,TMPZ(0.5-5mmol/L)did not significantly inhibit TBARS reaction in rat brain ***:The neuroprotective effect of TMPZ may be mediated at least by aportion of the inhibition of HIF-1αand TNF-αactivations,followed by the inhibi-tion of apoptosis formation(active caspase-3),resulting in a reduction in theinfarct volume in ischemia-reperfusion brain ***,TMPZ treatment mayrepresent an ideal approach to lowering the risk of or improving function in is-chemia-reperfusion brain injury-related disorders.

关键词： tetramethylpyrazine middle cerebral artery occlusion HIF-Iα caspase-3 TNF-α thiobarbituric acid-reactive substance

Synthesis,structure and properties of an imidazolate bridged copper,zinc binuclear complex

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chinese Journal of Chemistry 1992年第1期10卷 45-51页

作者： MAO,Zong-Wan CHEN,Dong TANG,Wen-Xia Coordination Chemistry Institute,Nanjing university,Nanjing 2.0008 YU,Kai-Bei LIU,Li Analysis Center,Chengdu Branch of The chinese {2. of sciences,Chengdu 610015 1Coordination Chemistry Institute Nanjing University Nanjing 2100082Analysis Center Chengdu Branch of The Chinese Academy of Sciences Chengdu 610015

A new imidazolate bridged Cu^(2.),Zn^(2.)binuclear complex[(dtma) CulmZn (dtma)]ClO_4· 2.5H_2. taken as active site model for Cu,Zn-SOD has been synthesized and its crystal structure *** the bond lengths, bond angles and the distance between Cu and Zn atoms in Cu-Im- Zn core of the model complex are close to those in Cu,*** parameters of the model complex as a function of pH show that the imidazolate bridge is stable in pH range 10—12.and is broken on Zn side at pH～*** decreasing pH,the imidazole is released at pH～4 and the dtma ligand dissociates from the Cu containing fragment at pH～2.4.

关键词： Cu Synthesis,structure and properties of an imidazolate bridged copper,zinc binuclear complex Zn

FKBP12.6 Knockout Increases Ryanodine Receptors Open Probability During β-adrenergic Stimulation in Mice Cardiac Myocytes

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FKBP12.6 Knockout Increases Ryanodine Receptors Open Probabi...

第十一次中国生物物理学术大会暨第九届全国会员代表大会

作者： Zhao Yanting1,Zhou Peng 1,Chen Zheng 2.Ji Guangju 2.Wang Shiqiang 1 1State Key Laboratory of Biomembrane and Membrane Biotechnology,College of Life sciences,Peking university,and 2.nstitute of Biophysics,{2. academy of sciences,Being,china,100871

＜正＞FK506 binding protein 12.6（FKBP12.6）is the protein in the ryanodine receptor complex,but its function is controversial in different reported *** conclude that FKBP12.6

关键词： β-adrenergic FKBP12.6 isoproterenol ryanodine receptor spark

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土壤氨氧化细菌的分离方法研究

土壤 2005年第5期37卷 569-571页

作者：胡君利林先贵褚海燕尹睿张华勇苑学霞朱建国中国科学院南京土壤研究所南京210008

氨氧化细菌是生态系统硝化过程中的一类重要微生物,但由于具有自养性、依附性和生长速率低等特性,从环境中分离氨氧化细菌存在很大困难。本研究通过改进硅胶平板的配方和制作程序,使土壤中氨氧化细菌能够快速高效地分离,有利于进一步开... 详细信息

氨氧化细菌是生态系统硝化过程中的一类重要微生物,但由于具有自养性、依附性和生长速率低等特性,从环境中分离氨氧化细菌存在很大困难。本研究通过改进硅胶平板的配方和制作程序,使土壤中氨氧化细菌能够快速高效地分离,有利于进一步开展对此菌的研究工作。

关键词：土壤氨氧化细菌硅胶平板分离

Blue light-specific regulation of CIB1 protein expression in Arabidopsis

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Blue light-specific regulation of CIB1 protein expression in...

THEORY OF FLUID-SOLID COUPLED FLOW THROUGH FRACTURED LOW-PERMEABILITY OIL RESERVOIR AND ITS APPLICATIONS

2.11全国植物生物学研讨会

作者： Hongtao Liu~1,Chentao Lin~2.1.Institute of Plant Physiol & Ecology,chinese academy of {2. 2.Department of Molecular,Cell and Developmental Biology,university of California,Los Angeles

Cryptochromes(CRY) are photolyase-like blue-light receptors that mediate light responses in plants and *** plant cryptochromes act in response to blue light is not well *** have recently reported the identification and characterization of the Arabidopsis CIB 1(cryptochrome-interacting basic-helix-loop-helix).CIB1 interacts with CRY2.cryptochrome 2. in a blue light-specific manner,and it acts with additional CIBl-related proteins to promote CRY2.dependent activation of FT gene expression and floral initiation and CIB1 binds to the FT protmoter in *** proposed that the blue light-dependent interaction of cryptochrome(s) with CIB1 and CIBl-related proteins represents an

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Journal of Hydrodynamics 2003年第2期15卷 121-122页

作者： Ph.D.Candidate:Liu Jian junInstitute of Porous Media Mechanics, Wuhan Polytechic university, Wuhan 43002., china Supervisor:Hu Yareng Institute of Porous Flow and Fluid Mechanics {2.,Acade my of sciences Institute of Porous Media Mechanics Wuhan Polytechic University Wuhan 430023 China

During the development of low permeability reservoirs. the interaction between fluid flow and rock mass deformation is obvious. On the basis of fluid mechanics in porous media and elasto plastic theory. the author presents an equivalent continuum model to simulate fluid flow in fractured low permeability oil reservoir coupled with geo stress. The model not only reflects the porosity change of matrix, but also the permeability change due to the opening and closing of fracture. By analyzing of simulation results, the changes in porosity and permeability and their effect on oil development are studied.

关键词： fluid solid interaction flow through porous media porosity permeability numerical simulation