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A quality evaluation strategy for a variety of sources of Rhizoma Coptidis: chromatographic fingerprint combined with biological fingerprint

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A quality evaluation strategy for a variety of sources of Rh...

China's Economic Reform(Ⅱ)

2.12.中国药学大会暨第十二届中国药师周

作者： Li JunXian1,2.Yan Dan2.Lina Ma2.3,Yan ChunXia1,2.Li BaoCai1,,Cheng Peng3,Xiao XiaoHe 2.1 College of Life Science and Technolog,Kunming university of Science and Technology,Kunming 650093,China 2.Military Institute of chinese Materia Medica,302.h Military Hospital of China,{2. 100039,China 3 College of Pharmacy,Chengdu university of Traditional chinese Medicine,Chengdu 610075,China

目的:一些具有确切生物活性的植物产品,由于材料基源的差异被划分为不同的等级。本试验以黄连为例,期望建立一种能更好的综合评价不同植物品种质量的方法。方法 :本试验采用HPLC结合微量量热法来建立三种不同基源的黄连（味连、雅连、... 详细信息

目的:一些具有确切生物活性的植物产品,由于材料基源的差异被划分为不同的等级。本试验以黄连为例,期望建立一种能更好的综合评价不同植物品种质量的方法。方法 :本试验采用HPLC结合微量量热法来建立三种不同基源的黄连（味连、雅连、云连）的色谱指纹图谱（CF）及生物指纹谱（BF）。从不同浓度的黄连对痢疾杆菌生长P-t曲线的影响得到相关生物学定量参数,并利用典型相关分析法（CCA）分析CF与BF之间的"谱效关系"。结果 :结果显示,"谱效关系"密切相关。在黄连药材中,药根碱,黄连碱,巴马汀和小檗碱是主要的抗菌成分。结论 :虽然黄连只是一个代表性的植物产品,但是上述方法也为其他品种植物药的质量评价提供了模范。所以,所以运用化学分析与生物分析相结合的方法来评估具有生物活性的植物产品的质量可行的。

关键词：黄连多基源质量控制化学指纹谱生物指纹谱

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International Understanding 1995年第1期 5-10页

作者： $$$$Li yining( chinese Association for International Understanding Professor, beijing {2.)

Ｃｈｉｎａ＇ｓＥｃｏｎｏｍｉｃＲｅｆｏｒｍ（Ⅱ）ＢｙＬｉｙｉｎｉｎｇ（Ｖｉｃｅ－ｐｒｅｓｉｄｅｎｔ，ＣｈｉｎｅｓｅＡｓｓｏｃｉａｔｉｏｎｆｏｒＩｎｔｅｒｎａｔｉｏｎａｌＵｎｄｅｒｓｔａｎｄｉｎｇ；Ｐｒｏｆｅｓｓｏｒ，...

Ｃｈｉｎａ＇ｓＥｃｏｎｏｍｉｃＲｅｆｏｒｍ（Ⅱ）ＢｙＬｉｙｉｎｉｎｇ（Ｖｉｃｅ－ｐｒｅｓｉｄｅｎｔ，ＣｈｉｎｅｓｅＡｓｓｏｃｉａｔｉｏｎｆｏｒＩｎｔｅｒｎａｔｉｏｎａｌＵｎｄｅｒｓｔａｎｄｉｎｇ；Ｐｒｏｆｅｓｓｏｒ，ＢｅｉｊｉｎｇＵｎｉｖｅｒｓｉｔｙ...

关键词：

四川盆地西部上三叠统须家河组二段风暴岩沉积特征

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石油与天然气地质 2003年第1期24卷 81-86页

作者：李华启姜在兴邢焕清鲜本忠中国科学院广州地球化学研究所石油大学地球资源与信息学院山东东营257061

通过研究 ,发现了四川盆地西部上三叠统须家河组二段沉积具有典型的风暴沉积特征 ,主要包括渠模构造 (或口袋构造 )、冲刷面和截切构造、风暴滞积层段、丘状交错层理、包卷层理、浪成层理、倒“小”字状构造、生物扰动等。须二段的风暴... 详细信息

通过研究 ,发现了四川盆地西部上三叠统须家河组二段沉积具有典型的风暴沉积特征 ,主要包括渠模构造 (或口袋构造 )、冲刷面和截切构造、风暴滞积层段、丘状交错层理、包卷层理、浪成层理、倒“小”字状构造、生物扰动等。须二段的风暴沉积类似于鲍马序列 ,垂向沉积序列可以划分出Sa,Sb ,Sc ,Sd ,Se等 5段。风暴沉积是由风暴作用引起的强烈振荡风暴浪作用于三角洲、扇三角洲 ,使沉积物经搬运再沉积的产物。风暴岩沉积构造类型丰富多样 ,而又以风暴成因的泥砾为特征 ,泥砾的形态 ,排列样式 ,组合方式 ,反映了风暴沉积的强度和频度。

关键词：四川盆地西部上三叠统须家河组风暴岩沉积特征沉积模型油气地质

Isolation and mutation rate of the spontaneous PUR box and purR mutants

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Progress in Natural Science:Materials International 2002年第5期 41-45页

作者： DAI Shipan , YANG Zhiwei , QIN Junchuan and WANG Aoquan( National Key Laboratory of Pharmaceutical Biotechnology, Nanjing university, Nanjing 2.0093, China Institute of Microbiology, chinese {2. of sciences, beijing 100080, China) National Key Laboratory of Pharmaceutical Biotechnology，Nanjing university，Nanjing 2.0093，China Institute of Microbiology，chinese academy of {2.，beijing 100080，China

In our previous research in purine metabolism in Salmonella typhimurium, it was observed that the mutation frequency of the PUR box was one order of magnitude higher than that of purR under mutagenesis. In order to investigate further into this phenomenon, large amounts of independent PUR box and purR spontaneous mutants were isolated on lactose minimal medium by using a super-repressing mutant of purR (purRs) . The mutational regions of 5 PUR box mutants and 4 purR mutants were cloned. Nucleotide sequence analysis showed that all the mutants had mutations at the expected sites. The comparison of the two types of mutations indicated that, although the purR gene was two orders of magnitude larger than the PUR box (100:1), the ratio of their mutation rate was only 7:3 (purR : PUR box) . Thus, we concluded that high mutation frequency of the PUR box did not result from mutagenesis. Under spontaneous conditions, the mutation frequency of PUR box was also high. Some tentative explanations of this interesting

关键词： super-repressing mutant PUR box purR .

Vernon Smith开创的实验经济学及其对心理学研究的启示

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心理科学进展 2003年第3期11卷 243-248页

作者：皇甫刚朱莉琪北京航空航天大学经济管理学院北京100083 中国科学院心理所心理健康重点实验室北京100101

2.02.度诺贝尔经济学奖得主Vernon Smith是实验经济学的创始人。他获奖的原因是“在实验经济分析尤其是选择性市场机制研究中引入了实验室实验”,开创了经济学研究的新领域。该文介绍了实验经济学的理论基础、其主要研究领域以及实验... 详细信息

2.02.度诺贝尔经济学奖得主Vernon Smith是实验经济学的创始人。他获奖的原因是“在实验经济分析尤其是选择性市场机制研究中引入了实验室实验”,开创了经济学研究的新领域。该文介绍了实验经济学的理论基础、其主要研究领域以及实验经济学的新方向——神经经济学的研究。该文着重介绍并分析了实验经济学中与心理学研究有关的部分,以期对心理学研究有所启示。

关键词： Vernon·Smith 实验经济学心理学研究选择性市场机制神经经济学建构主义理性生态理性

Neonatal exposure to fluoxetine and fluvoxamine altered spine density

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Neonatal exposure to fluoxetine and fluvoxamine altered spin...

Design and research of RF system for 10 MeV compact cyclotron

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Ting-Jia LU~(1,2.,Ya-Jie SUN~(1,3),Xue-Han ZHANG~4,Bao-Ming LI~4,Xiao-Hua CAO~5,Zhi-Qi XIONG~(1,2. 1 Institute of Neuroscience and Key Laboratory of Neurobiology,Shanghai Institutes for Biological sciences,chinese {2. of sciences,Shanghai 2.0031,China 2.graduate School of the chinese {2. of sciences,Shanghai 2.0031,China 3 Hangzhou Normal university,Hangzhou 310036,China 4 Laboratory of Higher Brain Functions, Institute of Neurobiology,Fudan university,Shanghai 2.0433,China 5Laboratorory of Synaptic Plasticity and Learning Behavior,Shanghai Institute of Brain Functional Genomics,East China Normal university,Shanghai 2.0062.China

＜正＞Early-life exposure to SSRI antidepressants increases the chances of developing mood disorders later in life. However,the biological basis in term of neuronal morphology for these behavioral changes is ***,we have employed animal models,mimicking maternal use of SSRIs in clinical,to study neonatal exposure to SSRIs on neuronal *** used confocal microscopy to investigate the acute and long-lasting effects of SSRI administration during early life on dendritic spine density in hippocampal CA1 pyramidal *** observed an acute decrease,and a delayed increase,in dendritic spine density of CA1 pyramidal *** detrimental changes in neuronal morphology were associated with decreased locomotor ***,our findings demonstrate that neonatal exposure to SSRIs is capable of influencing the morphological plasticity of excitatory synapses and raise the caution of clinical medication with SSRIs especially in pregnant women.

关键词： early life SSRI dendritic spine

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Science China(Physics,Mechanics & Astronomy) 2011年第S2期54卷 225-230页

作者： Dong Li (1) TongNing Hu (2. KaiFeng Liu (1) Jun Yang (1) 1. College of Electrical and Electronic Engineering Huazhong University of Science and Technology Wuhan 430074 China2. Department of Electronics and Information Engineering Huazhong University of Science and Technology Wuhan 430074 China

A 10 MeV compact cyclotron (CYCHU-10) has been developing in Huazhong university of Science and Technology (HUST). The RF system includes a 10 kW RF power generator and a resonance cavity. There is no automatic frequency tuning equipment in the cavity due to space limitations, so the generator must search and track the cavity resonant frequency. AD9850 synthesizer is used to generate RF signal in the experimental prototype, and a fine sinusoidal waveform around 99 MHz is obtained with the method of picking up a special aliased signal from the synthesizer's output, and the output power level can be set by regulating the resistor connected to the Pin 'Rset'. The final stage amplifier based on tetrode operates in the grounded cathode configuration, and the schematic of the tetrode circuit is illustrated. The method of searching the resonant frequency is discussed in detail. For the sake of a compact and robust structure, the resonance cavity will adopt non-uniform characteristic impedance coaxial structure, and the magnet surface electroplated with copper will be used as dummy Dees. The precise shapes and dimensions of the cavity are designed and simulation results are carried out in this paper. The distributions of electromagnetic field are illustrated by means of numerical calculation analysis, and the wooden model test is preformed as well.

关键词： compact cyclotron RF system AD9850 tetrode resonance cavity

殊化信任与泛化信任在人际信任行为路径模型中的作用

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心理学报 2000年第3期32卷 311-316页

作者：张建新张妙清梁觉中国科学院心理研究所!北京100101 香港中文大学心理系

该研究探讨不同社会情景下，泛化信任、殊化信任以及可信任性知觉等对信任行为起作用的理论模型。2.3名工人被试平均年龄2.岁。用结构方程模型中的路径分析验证该模型，结果表明，各种拟合指标十分理想。三种交往情景下的人际信任路径... 详细信息

该研究探讨不同社会情景下，泛化信任、殊化信任以及可信任性知觉等对信任行为起作用的理论模型。2.3名工人被试平均年龄2.岁。用结构方程模型中的路径分析验证该模型，结果表明，各种拟合指标十分理想。三种交往情景下的人际信任路径模型之间的异同主要表现在：（1）殊化信任在所有情景下对信任行为都有直接而显著的作用；（2.泛化信任则只在与熟人和陌生人交往时才起作用；（3）与目标人物的关系越疏远，对他们作出信任行为时所需要的心理资源也越多。

关键词：人际信任结构方程模型目标人物

The Synthesis of 3-(2.-Hydroxybutyl) isobenzofuran-1 (3H)-one

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chinese Chemical Letters 1999年第1期10卷 21-22页

作者： Guo Xin WANG Guo HSO XIE Yuan Liu WU Xin Fu PAN(Laboratory of Applled Organic Chemistry，Institute of Organlc Chemistry． Lanzhou university，Lanzhou，730000)(Instltute ofMateria Medica, chinese {2. of Medical Science，beijing 100050)(Department of Lanzhou Univ Inst Organ Chem Lab Appl Organ Chem Lanzhou 730000 Peoples R China chinese Acad Med Sci Inst Mat Med Beijing 100050 Peoples R China Shangrao Normol Coll Dept Chem Shangrao 334001 Peoples R China

The synthesis of 3-(2.-hydroxybutyl）isobenzofuran-1(3H)-onel from phthalicanhydride via the intermediate 3-(2.-oxoethyl) isobenzofuran-1(3H)-one 6 was described．

关键词： Synthesis 3-(2.-hydroxybutyl)lsobenzofuran-1(3H)-one.