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Isoprenaline enhances local Ca2+ release in cardiac myocytes

Acta pharmacologica Sinica 2006年第07期27卷 927-932页

作者： Jian-xin SHEN~(2,3,42.department of physiology,Shantou university Medical College,Shantou 515041,China 3 department of physiology,Medical School of Xi'an Jiaotong university,Xi'an 710061,China departmentofphysiology ShantouUniversityMedicalCollegeShantou515041China departmentofphysiology MedicalSchooloJXi'anJiaotongUniversityXi'an710061China

Aim:Contraction of cardiac myocytes is controlled by the generation and ampli-fication of intracellular Ca2+*** key step of this process is the couplingbetween sarcolemma L-type Ca2+channels（LCCs）and ryanodine receptors（RyRs）in the sarcoplasmic reticulum（SR）.β-Adrenergic stimulation is an important regu-latory mechanism for this coupling *** the details underlied the globallevel,which require local Ca2+release study are still *** present study isto explore the effects of β-adrenergic stimulation on local Ca2+***:Using confocal microscopy combined with loose-seal patch-clamp approaches,effects of isoprenaline(1 μmol·L-1),a β-adrenergic agonist,on local SR Ca2+re-lease triggered by Ca2+influx through LCCs in intact rat cardiac myocytes ***:Isoprenaline increased the intensity of ensemble averagedlocal Ca2+transients,the peak of which displayed a typical bell-shaped voltage-dependence over the membrane voltages ranging from～-40mV to～+35m ***-ther analysis showed that this enhancement could be explained by the increasedcoupling fidelity（which refers the increased probability of RyRs activation upondepolarization）,and the increased amplitude of evoked Ca2+sparks(due to moreCa2+releases through local RyRs).In addition,isoprenaline decreased the firstlatency,which displayed a typical"U"-shaped voltage-dependence,showing theavailable acceleration and synchronization of β-adrenergic stimulation on intrac-ellular calcium ***:Isoprenaline enhances local Ca2+release incardiac *** results underscore the importance of regulation of β-adrenergic stimulation on local intermolecular signals between LCCs and RyRs inheart cells.

关键词： local calcium release calcium signaling cardiac myocytes isoprenaline confocal microscopy

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THE AVERAGE DISTANCE OF TREES

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Systems Science and Mathematical Sciences 1993年第1期6卷 18-24页

作者： SHI Ronghua department of Applied mathematics, East China Institute of Technology,Nanjing 210014, China

In this paper, we investigate the average distance of trees, prove Conjecture592 presented by the computer program Graffiti, and present two infinite sets of counterex-amples to the Conjectures 583 and 587, respectively.

关键词： Degree distance average distance tree

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Characterization of static bifurcations for n-dimensional flows in the frequency domain

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Control Theory and Technology 2006年第3期4卷 217-222页

作者： Li ZENG, Yi ZHAO (department of mathematics, Sun Yat-Sen university, Guangzhou Guangdong 510275, China School of Informatics, Guangdong university of Foreign Studies, Guangzhou Guangdong 510006, China department of mathematics, Sun Yat-Sen university, Guangzhou Guangdong 510275, China) department of mathematics Sun Yat-Sen University Guangzhou Guangdong 510275 China School of Informatics Guangdong University of Foreign Studies Guangzhou Guangdong 510006 China

In this paper n-dimensional flows (described by continuous-time system) with static bifurcations are considered with the aim of classification of different elementary bifurcations using the frequency domain formalism. Based on frequency domain approach, we prove some criterions for the saddle-node bifurcation, transcritical bifurcation and pitchfork bifurcation, and give an example to illustrate the efficiency of the result obtained.

关键词： Static bifurcation Frequency domain approach Saddle-node bifurcation Transcritical bifurcation pitchfork bifurcation

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THE ASSOCIATIVE BCI-ALGEBRA

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Chinese Science Bulletin 1982年第11期27卷 1143-1146页

作者：胡庆平 ISKI K. department of mathematics Northwest University Xi'an department of mathematics Kobe University Japan

In 1966, Imai, Y. and the latter author of this paper introduced the BCK-algebra in the following Definition 1. Let X be a set with a binary operation * and a constant 0. Then X is called a BCK-algebra, if it satisfie... 详细信息

关键词： algebra latter semigroup satis inverse distinguish arbitrary holds 主一 assoc

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Free Volume Changes in γ-Irradiated polyethylene and polytetraflourethylene

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Journal of Materials Science & Technology 2000年第3期16卷 302-304页

作者： Xianyi ZHOU (Dept. of Modern physics, university of Science and Technology of China, Hefei 230027, China) Linhua ZHAI (department of physics, Anhui Normal university, Wuhu 241000, China) Jiangfeng DU and Rongdian HAN (department of Modern physics, Univers department of Modern physics University of Science and Technology of China Hefei 230027 China department of physics Anhui Normal University Wuhu 241000 China

positron lifetime spectrum was measured and the change of the free volume was studied for commercial polyethylene (pE) and polytetrafluoroethylene (pTFE) during 7-irradiation processing up to 265 kGy. The free volume size increases but the crystallinity decreases as irradiation dose increases in pE. Both qualities (free volume size and crystallinity) in pTFE display an opposite behavior. The fractional free volume reduces monotonically with increasing irradiation dose in both pE and pTFE. The competition between the crosslinkmg and the splitting decomposition in polymers can be used to understand the free volume changes with irradiation dose.

关键词： pTFE Irradiated polyethylene and polytetraflourethylene

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B值拟鞅差序列加权和的收敛性与大数律

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武汉大学学报（理学版） 2002年第3期48卷 281-284页

作者：邱德华甘师信衡阳师范学院数学系湖南衡阳421008 武汉大学数学与统计学院湖北武汉430072

{Xn,Fn,n≥1}为B值p拟鞅,{anj}为实值常数阵列,在{}关于{}一致可积的条件下,建立了anjdjX的收敛性与Banach空间p光滑性的关系,并在p光滑Banach空间中,给出anjdjX的强大数定律及完全收敛定理.

关键词： B值似鞅差序列加权和收敛性大数律

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The reconstruction and interpretations of lake status at 6 ka and 18 ka *** inland mainland Asia

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Chinese Science Bulletin 1998年第14期43卷 1145-1157页

作者： QIN Boqiang 1, SHI Yafeng 1 and YU Ge 2, 3 1. Nanjing Institute of Geography & Limnology, Chinese Academy of Sciences, Nanjing 210008, China 2. Dynamic palaeoclimatology, Lund university, pO Box 117, S 221 00, Lund, Sweden 3. department of Nanjing Institute of Geography & Limnolagy Chinese Academy of Sciences Nanjing China Dynamic palaeoclimatology Lund University Lund Sweden department of Geology and Ocean Sciences Nanjing University Nanjing China

By means of survey of literature through compilations of sedimentological, biogeological and geomorphologic data, the inland lake level changes in arid or semi arid mainland Asia at 6 and 18 ka B.p. have been reconstructed. The results showed that the lakes from western and northwestern Asia were characterized by very high water levels at 18 ka B.p., but low or intermediate water stands at 6 ka B.p. The high lake level in this region was associated with the southward displacement of westerlies, therefore, the extent of the high lake stand indicated the southern flank of westerlies during the glaciation. Conversely, the lakes from the eastern and southern Asia registered comparative low levels at 18 ka B.p. and significantly high one at 6 ka B.p. The lowering of lake level at 18 ka B.p. was caused by the weakened summer monsoon and the high lake level at 6 ka B.p. by the enhanced summer monsoon induced by the enlarged thermal contrast between land and ocean. The extent of high lake levels indicated the northern boundary of monsoon expansion. Between the above two regions, there is a climatic transitional zone in the Central Asia where the lake behavior was close to that in southeastern Asia at 6 ka B.p. but became similar to that in northwestern Asia at 18 ka B.p. Thus this zone became a transitional sector from the monsoon to the westerlies.

关键词： lake status inland mainland Asia westerlies monsoon.

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8mm波段三次谐波复合腔回旋管的非线性分析

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物理学报 2001年第10期50卷 1979-1983页

作者：喻胜李宏福谢仲怜罗勇襄樊学院物理系襄樊441002 成都电子科技大学高能电子研究所成都610054

利用含电流的传输线方程 ,在考虑了诸多实际因素影响的情况下 ,对三次谐波渐变复合腔回旋管进行了自洽非线性模拟 ,计算了H51 1 H52 1 模式下三次谐波多模注波互作用 ,分析了电子注的厚度、速度零散。

关键词：三次谐波非线性分析回旋管复合腔多模注波互作用速度零散速度比电子注

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Variation of reactivity of particulate and sedimentary organic matter along the Zhujiang River Estuary

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Acta Oceanologica Sinica 2003年第4期22卷 557-568页

作者： Chen Jianfang 1,2, Jin Haiyan 1,2, Yin Kedong3, Li Yan 1,2 1. Key Laboratory of Submarine Geosciences of State Oceanic Administration, Hangzhou 310012, China. 2. Laboratory of Regional Oceanography, Second Institute of Oceanography, State Oceanic Aedministration, Hangzhou,310012, China 3. department of Biology, Hong Kong university of Science and Technology, Hong Kong Kay Lab Submarine Geosci State Ocean Adm Hangzhou 310012 Peoples R China State Ocean Adm Inst Oceanog 2 Lab Reg Oceanog Hangzhou 310012 Peoples R China Hong Kong Univ Sci & Technol Dept Biol Hong Kong Hong Kong Peoples R China

To investigate organic matter source and reactivity in the Zhujiang River (pearl River) Estuary and its adjacent areas, particulate organic carbon (pOC), particulate hydrolysable amino acids (pHAA), and Chl a during two cruises in July 1999 and July 2000 were measured. The highest pOC and pHAA concentration was observed in the waters with maximum Chl a. The spectra distribution, relative content (dry weight in milligram per gram), pHAA-C% pOC and other indicators such as the ratios of amino acids vs. amino sugars (AA/AS) and glucosamine vs. galactosamine (Glum/Gal) suggested that particulate amino acids in the water column and sediments in the Zhujiang River Estuary were mainly derived from biogenic processes rather than transported from terrestrial erosion. In inner estuary where high turbidity was often observable, organic matter was mainly contributed by re-suspension of bottom sediments with revealed zooplankton, microbial reworked characteristics, which suggest that these organic matters were relatively 'old'. In the estuarine brackish region, organic matter in water column is mainly contributed by relatively fresh, easily degradable phytoplankton derived organic matter. During physical - biological processes within the eastuary, organic matter derived from phytoplankton was subjected to alteration by zooplankton grazing and bacterial reworking.

关键词： organic matter reactivity amino acids the Zhujiang River Estuary

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The functional central limit theorem for strong near-epoch dependent random variables

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progress in Natural Science:Materials International 2004年第1期 10-15页

作者： QIU Jin 1,2 * and LIN Zhengyan 1(1. department of mathematics, Zhejiang university, Xixi Campus, Hangzhou 310028, China 2. Information School, Zhejiang university of Finance and Economics, Hangzhou 310012, China) InformationSchool ZhejiangUniversityofFinanceandEconomicsHangzhou310012China departmentofmathematics ZhejiangUniversityXixiCampusHangzhou310028

The functional central limit theorem for strong near epoch dependent sequences of random variables is proved. The conditions given improve on previous results in the literature concerning dependence and heterogeneity.

关键词： mixing near epoch dependent strong near epoch dependent functional central limit theorem

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