检索结果-南通市图书馆

Evidence-based expert consensus on clinical management of safety of Bruton’s tyrosine kinase inhibitors(2.2.)

chinese Journal of Cancer Research 2024年第3期36卷 240-256页

作者： Zaiwei Song Dan Jiang Lingling Yu Yixuan Chen Daobin Zhou Yue Li Depei Wu Lingli Zhang Liyan Miao Jun Ma Jun Zhu Hongmei Jing Rongsheng Zhao the Steering Committee,the Consensus Panel and the Evidence Synthesis Group Evidence-based Pharmacy Professional Committee of chinese pharmaceutical Association(CPA) Hospital Pharmacy Professional Committee of chinese pharmaceutical Association(CPA) Division of Therapeutic Drug Monitoring of chinese Pharmacological Society(CPS) Expert Committee on Lymphoma of chinese Society of Clinical Oncology(CSCO) Expert Committee on Leukemia of chinese Society of Clinical Oncology(CSCO) Society of Integrative Cardio-Oncology of china Anti-Cancer Association(CACA) chinese Society of Hematology of chinese Medical Association(CMA) Hospital Pharmacy Professional Committee of Cross-Straits medicine Exchange Association(SMEA) Department of Pharmacy Peking University Third HospitalBeijing 100191China Institute for Drug Evaluation Peking University Health Science CenterBeijing 100191China Therapeutic Drug Monitoring and Clinical Toxicology Center Peking UniversityBeijing 100191China Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Hematology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China Department of Cardiology the First Affiliated HospitalHarbin Medical UniversityHarbin 150001China Department of Hematology the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Pharmacy Evidence-based Pharmacy CenterWest China Second HospitalSichuan UniversityChengdu 610041China Department of Pharmacy the First Affiliated Hospital of Soochow UniversitySuzhou 215006China Department of Hematology and Oncology Harbin Institute of Hematology and OncologyHarbin 150010China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of LymphomaPeking University Cancer Hospital&InstituteBeijing 100142China Department of Hematology Peking University Third HospitalBeijing 100191China 不详

Bruton’s tyrosine kinase inhibitors(BTKis)have revolutionized the treatment of B-cell ***,safety issues related to the use of BTKis may hinder treatment continuity and further affect clinical efficacy.A comprehensive and systematic expert consensus from a pharmacological perspective is lacking for safety issues associated with BTKi treatment.A multidisciplinary consensus working group was established,comprising 35 members from the fields of hematology,cardiovascular disease,cardio-oncology,clinical pharmacy,and evidencebased *** evidence-based expert consensus was formulated using an evidence-based approach and the Delphi *** Joanna Briggs Institute Critical Appraisal(JBI)tool and Grading of Recommendations Assessment,Development,and Evaluation(GRADE)approach were used to rate the quality of evidence and grade the strength of recommendations,*** consensus provides practical recommendations for BTKis medication based on nine aspects within three domains,including the management of common adverse drug events such as bleeding,cardiovascular events,and hematological toxicity,as well as the management of drug-drug interactions and guidance for special *** multidisciplinary expert consensus could contribute to promoting a multi-dimensional,comprehensive and standardized management of BTKis.

关键词： Consensus BTK inhibitors safety adverse drug events drug-drug interactions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigation of the differences between the “COLD” and “HOT” nature of Coptis chinensis Franch and its processed materials based on animal’s temperature tropism

引用

Science china(Life Sciences) 2009年第11期52卷 1073-1080页

作者： ZHOU CanPing1,2. WANG JiaBo1, ZHANG XueRu1,2. ZHAO YanLing1, XIA XinHua2. ZHAO HaiPing1, REN YongShen1 & XIAO XiaoHe1 1 china Military Institute of chinese Meteria Medica, 302.Military Hospital of china, Beijing 100039, china 2.college of pharmaceutical Sciences, hunan university of chinese medicine, changsha 4102.8, china china Military Institute of chinese Meteria Medica 302 Military Hospital of China Beijing 100039 China college of pharmaceutical Sciences Hunan University of Chinese Medicine Changsha 410208 China

The description and differentiation of the so-called "Cold" and "Hot" natures, the primary "Drug Naure" of chinese medicine, is the focus of theoretical research. In this study, the divergency between the "Cold" and the "Hot" natures was investigated through examining the temperature tropism of mice affected by Coptis chinensis Franch and its processed materials by using a cold/hot plate differentiating technology. After exposure to C. chinensis Franch, the macroscopic behavioral index of the remaining rate (RR) on a warm pad (40℃ ) significantly increased (Pchinese medicine may possibly reflect in an ethological way for the changes of animal’s temperature tropism which might be internally regulated by the body’s energy metabolism.

关键词： "Cold" and "Hot" natures of chinese medicine evaluation temperature tropism ethology drug process Coptis chinensis Franch

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A new orthogonality relationship for orthotropic thin plate theory and its variational principle

引用

Science china(Physics,Mechanics & Astronomy) 2005年第3期48卷 371-380页

作者： LUO Jianhui 1 , LONG Yuqiu 2.& LIU Guangdong 1 1. college of Civil Engineering, hunan {2., changsha 410082. china 2. Department of Civil Engineering, Tsinghua {2., Beijing 100084, china 1. college of Civil Engineering Hunan University 410082 Changsha China 2. Department of Civil Engineering Tsinghua University 100084 Beijing China

The thought how dual vectors are constructed in a new orthogonality relationship for theory of elasticity is generalized into orthotropic thin plate bending problems by using the analogy theory between plane elasticity problems and plate bending problems. Dual differential equations are directly obtained by using a mixed variables method. A dual differential matrix to be derived possesses a peculiarity of which principal diagonal sub-matrixes are zero matrixes. Two independently and symmetrically orthogonality sub-relationships are discovered. By using the integral form for elastic bending theory of orthotropic thin plate the orthogonality relationship is demonstrated. By selecting felicitous dual vectors a new orthogonality relationship for theory of elasticity can be generalized into elastic bending theory of orthotropic thin plate. By using the integral form a variational principle which is relative to differential form and a whole function expression are proposed.

关键词： theory of elasticity, thin plate theory, dual vectors, orthogonality relationship, orthotropic, variational principle.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stress Echocardiography for Chronic Coronary Syndrome:Clinical Practice Guidelines(2.2.)

引用

Journal of Geriatric Cardiology 2024年第5期21卷 475-505页

作者： Peng-Fei ZHANG Jia-Wei TIAN Tian-Gang ZHU Jue-Fei WU Xiao-Ping LENG Yi WANG Meng-Meng LI Xin-Hao LI Qian-Qian WANG Xiao-Peng FENG Jia-Yan LV Li-Xue YIN Yun ZHANG Mei ZHANG chinese Society of Echocardiography,Superficial Tissue and Vascular Group of chinese Society of Ultrasound in {2.,Ultrasound Professional Committee of chinese {2. Education Association State Key Laboratory for Innovation and Transformation of Luobing Theory Key Laboratory of Cardiovascular Remodeling and Function ResearchChinese Ministry of EducationChinese National Health Commission and Chinese Academy of Medical SciencesDepartment of CardiologyQilu Hospital of Shandong UniversityJinanChina The Second Affiliated Hospital of Harbin Medical university HaerbinChina Peking university People's Hospital BeijingChina Sichuan Province People's Hospital ChengduChina Nanfang Hospital Southern Medical UniversityGuangzhouChina Peking Union Medical college Hospital Chinese Academy of Medical SciencesBeijingChina 不详

In the context of the People's Republic of china,coronary artery disease(CAD)presents a sig-nificant clinical challenge,with over 11.3 mil-lion patients ***,the diagnos-is of CAD has predominantly relied on invasive coronary angiography.[1]However,recent advances in clinical research have revealed a notable trend:a substantial 82. of patients subjected to such invas-ive diagnostics do not necessitate interventional therapy.

关键词： coronary clinical patients

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Resolution of α-cyclohexyl-mandelic acid enantiomers by two-phase (O/W) recognition chiral extraction

引用

Science china Chemistry 2007年第6期50卷 764-769页

作者： TANG KeWen1,2. ZHANG GuoLi2. HUANG KeLong2. LI Yuanjian3 & YI JianMin1,2.1 Department of Chemistry and Chemical Engineering, hunan Institute of Science and Technology, Yueyang 414000, china {2. of Chemistry and Chemical Engineering, Central South university, changsha 410083, china 3 college of pharmaceutical Science, Central South university, changsha 410078, china Department of Chemistry and Chemical Engineering Hunan Institute of Science and TechnologyYueyang 414000China college of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China

This paper presents a new chiral separation technology:two-phase(O/W)recognition chiral *** behavior of alpha-cyclohexyl-mandelic acid enantiomers was studied in the extraction system with D(L)-isobutyl tartrate in 1,2.dichloroethane organic phase and beta-CD derivatives in aqueous phase,and the influence of the kind and concentration of extractant and pH on extraction performance was *** experimental results indicate that two-phase(O/W)recognition chiral extraction is of strong chiral separation ***-^-CD,HE-beta-CD and Me-beta-CD have higher recognition ability for S-CHMA than that for R-CHMA,among which HP-beta-CD has the strongest ability;whereas,D-isobutyl tartrate has reversed recognition ability for *** the extraction system containing HP-beta-CD and D-isobutyl tartrate,e.e.% of S-CHMA in aqueous phase reached 2..6% by one stage extraction,and the distribution ratio for R-CHMA(k_R)and for S-CHMA(k_S)and separation factor(alpha)are 2.44,0.89 and 2.49,***,pH and concentration of extractant have great effects on chiral separation ***-phase(O/W)recognition chiral extraction has great significance for preparative separation of racemic compounds.

关键词： two-phase(W/0)recognition chiral extraction alpha-cyclohexyl-mandelic acid enantiomers

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Aspects of recent developments in analytical chemometrics

引用

Science china Chemistry 2006年第3期49卷 193-203页

作者： LIANG Yizeng1,2. WU Hailong1, SHEN Guoli1, JIANG Jianhui1, LIANG Sheng2.& YU Ruqin1 1. State Key Laboratory of Chemo/Biosensing and Chemometrics, college of Chemistry and Chemical Engineering, hunan {2., changsha 410082. china 2. Research Center of Modernization of Traditional chinese medicines, Central South {2., changsha 410081, china 1. State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China 2. Research Center of Modernization of Traditional chinese medicines Central South University Changsha 410081 China

Some aspects of recent developments in analytical chemometrics are discussed, in par- ticular the developments viewed from the angle of the research efforts undertaken in authors’ labora- tories. The topics concerned include resolution of high-order chemical data, morphological theory and methodology for chemical signal processing, multivariate calibration and chemical pattern recognition for solving complex chemical problems, and resolution of two-way chemical data from hyphenated chromatographic instruments.

关键词： chemometrics, high-order chemical data, pattern recognition, multivariate calibration and resolution.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development of simple sequence repeats (SSR) markers of ramie and comparison of SSR and inter-SSR marker systems

引用

Progress in Natural Science:Materials International 2005年第02期15卷 42-47页

作者： ZHOU Jianlin1*, JIE Yucheng2., JIANG Yanbo2. ZHONG Yingli1, LIU Yunhai1 and ZHANG Jian1**(1. Department of Biochemistry and Molecular Biology, college of Life Science, hunan Normal {2., changsha 410081, china 2. Institute of Bast Fiber Crops, chinese Academy of Agricultural Science, changsha 410006, china) Department of Biochemistry and Molecular Biology College of Life Science Hunan Normal University Changsha 410081 China. Institute of Bast Fiber Crops Chinese Academy of Agricultural Science Changsha 410006 China

Ramie (Boehmeria nivea L.) is an important bast fiber crop. To study genetic background of this species, we isolated and characterized microsatellite markers of ramie. A genomic library containing inserts of rapid amplification of polymorphic DNA (RAPD) fragments was constructed, and screened by PCR amplification using anchored simple sequence repeats as primers. A total of 2. clones were identified as positives, and 13 microsatellite loci were found after sequencing. The polymorphism of these 13 microsatellite loci was examined and the utility of simple sequence repeats (SSR) and inter-SSR (ISSR) marker systems for genetic characterization compared using 19 selected ramie cultivars. Both approaches successfully discriminated the 19 cultivars which differed in the amount of polymorphism detected. The level of polymorphism detected by SSR was 95.0%, higher than that by ISSR (72.3%), but the average polymorphism information content (PIC) of ISSR (0.651) was higher than that of SSR (0.441). The higher PIC value of ISSR suggests that ISSR is more efficient for fingerprinting ramie cultivars than SSR markers. However, because the SSR loci are codominant, they are more suitable for determining the homozygosity levels of ramie, constructing linkage map, quantitative trait loci study of complex traits and marker-assisted selection.

关键词： ramie (Boehmeria nivea L.Gaud) simple sequence repeats inter-simple sequence repeats

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Research on the method for retrieving soil moisture using thermal inertia model

引用

Science china Earth Sciences 2006年第5期49卷 539-545页

作者： LIU Zhenhua1 & ZHAO Yingshi2.1. Information college, South china Agricultural {2., Guangzhou 510642. china 2. Graduate {2. of chinese Academy of Sciences, Beijing 100049, china 1. Information college South China Agricultural University Guangzhou 510642 China 2. Graduate university of chinese Academy of Sciences Beijing 100049 China

In order to improve accuracy of soil moisture inversion using remote sensing, a new thermal inertia model is proposed in this paper. The improved model needs only surface maximum temperature as the temperature parameter input instead of input of the surface temperature difference, as well as the surface sensible and latent fluxes are introduced into boundary conditions of thermal conductivity equation. Furthermore, surface soil conductive heat transfer equation of two-layer model is used to solve the soil thermal inertia so that the remote sensing thermal inertia method can be ap- plied to regions with better-covered vegetation, but usually only for the bare areas or worse vegetation covered areas. The model has been tested at several locations in the area of west Inner Mongolia. Comparing the simulation of the new model with the measurements obtained by apparent thermal inertia and by field test, the result shows that the inertia thermal model can be used to estimate soil moisture in more reasonable accuracy.

关键词： thermal model, thermal conductivity equation, soil initial, sensible flux, latent flux, two-layer model.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Architecture and application of integrated spatial information service platform for digital mine

引用

中国有色金属学会会刊：英文版 2011年第S3期21卷 706-711页

作者： ZHANG Jin1, XIAO Jie2.1. college of Mining, Taiyuan university of Technology, Taiyuan 03002.,{2. 2. Institute of Geodesy and Geophysics, chinese Academy of Sciences, Wuhan 430077,{2. Taiyuan Univ Technol Coll Min Taiyuan 030024 Peoples R China chinese Acad Sci Inst Geodesy & Geophys Wuhan 430077 Peoples R China

Using enterprise GIS platform, spatial databases and modern information technology, building geo-spatial information service platform of digital mine which has the features of the data exchange service, enterprise GIS services, directory services, logging services, is key technology and application infrastructure for digital mine. Based on the support of geospatial information service platform of digital mine, the professional GIS application service adapter can be developed and the application supports related to mining application system can be realized. Using high-resolution satellite remote sensing data, the mine functional partition map and geographic grids can be divided, and the geographic grid parts, status and events of important features of the surface object were investigated and defined. The system architecture and technical characteristics of integrated spatial information service platform were analyzed firstly, which guarantee service ability of digital mine. The methods and applications of functional partition map for integrated management service platform were discussed which are the services scheme of digital mine. The application results indicated that digital mine upgrades and enhances the capability and range of mine surveying and mapping, and is of great significance for guarantee of efficient, green and intensive exploitation of mine.

关键词： platform architecture web services application services digital mine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pattern phenomena in an rf discharge dusty plasma system

引用

Science china(Physics,Mechanics & Astronomy) 2006年第5期49卷 588-596页

作者： HUANG Feng1,2. YE Maofu2.& WANG Long2.1. college of Science, china Agricultural {2., Beijing 100083, china 2. Institute of Physics, chinese Academy of Sciences, Beijing 100080, china 1. college of Science China Agricultural University Beijing 100083 China 2. Institute of Physics Chinese Academy of Sciences Beijing 100080 China

Various dust patterns are observed in an rf discharge dusty plasma system. According to the dust growth process from small to large in size, the formation of different dust patterns can be divided into two stages: the small-particle stage (or dust cloud stage), and the large-particle stage (or dust crystal stage). The evolution relations between different dust patterns with gas pressure changing are investigated. Dust voids, dust acoustic waves and strong turbulence modes are presented at the small-particle stage. The self-organized dust lattices and dust clusters are investigated at the large-particle stage. The static structure of a dust lattice is characterized by means of the pair correlation function. Dust clusters formed by particles with different numbers and the regular evolution of the clusters with gas pressure are also investigated. The packing sequences of dust clusters are verified through two-dimensional confined molecular dynamics simulations.

关键词： dusty plasma dust patterns

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：