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Dynamic modeling of cellular response to DNA damage based on p53 stress response networks

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Progress in Natural science:materials International 2009年第10期19卷 1349-1356页

作者： Jinpeng Qi,Yongsheng Ding,Shihuang Shao college of Information sciences and Technology,donghua university,shanghai 201620,china [a]college of Information sciences and Technology Donghua University Shanghai 201620 China

Under acute perturbations from the outside,cells can trigger self-defensive mechanisms to fight against genome *** investigate the cellular response to continuous ion radiation(IR),a dynamic model for p53 stress response networks at the cellular level is *** model can successfully be used to simulate the dynamic processes of double-strand breaks(DSBs) generation and their repair,switch-like ataxia telangiectasia mutated(ATM) activation,oscillations occurring in the p53-MDM2 feedback loop,as well as toxins elimination triggered by p53 stress response ***,the model can predict the plausible outcomes of cellular response under different IR dose regimes.

关键词： p53 DNA damage IR Cellular networks Modelin

Electrochemical Characteristic of Decarburization Reaction

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International Journal of Minerals,Metallurgy and materials 1999年第1期13卷 27-30页

作者： Xionggang Lu Fushen Li Lifen Li Kouchih Chou (Applied science School, university of science and Technology Beijing, Beijing 100083, china)(material science and engineering School, shanghai university, shanghai 200072, china) Applied science School University of Science and Technology Beijing Beijing 100083 China material science and engineering School Shanghai University Shanghai 200072 China

The electrochemical mechanism of the reaction between Fe-C melts and CaO-SiO2-Al2O3-FeOx slag systems has been carried out. The experimental results suggest that the final content of carbon in melt increases as the partial oxygen pressure of gas decreases no matter whether there is electronic conductor or not. However, the final content of carbon in the system with electronic conductor is much lower than that without electronic conductor. It can be deduced that the transfer ability of oxygen in slag is dominated by electrons. When an electronic conductor exists, an easy pathway for the electrons is provided and the oxygen transfer rate is accelerated.

关键词： melt-slag reaction decarburization electrochemistry electronic conductor

A NOVEL INTERPRETATION OF CONCENTRATION DEPENDENCE OF VISCOSITY OF DILUTE POLYMER SOLUTION

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Chinese Journal of Polymer science 2000年第1期18卷 57-67页

作者： Yan Pan Rong-shi Cheng college of material science and engineering, South china university of Technology, Guangzhou 510641, china college of Chemistry and Chemical engineering, Nanjing university, Nanjing 210093, china S china Univ Technol Coll Mat Sci & Engn Guangzhou 510641 Peoples R China Nanjing Univ Coll Chem & Chem Engn Nanjing 210093 Peoples R China

The concentration dependence of the reduced viscosity of dilute polymer solution is interpreted in the light of a new concept of the self-association of polymer chains in dilute solution. The apparent self-association constant is defined as the molar association constant divided by the molar mass of individual polymer chain and is numerically interconvertible with the Huggins coefficient. The molar association constant is directly proportional to the effective hydrodynamic volume of the polymer chain in solution and is irrespective of the chain architecture. The effective hydrodynamic volume accounts for the non-spherical conformation of a short polymer chain in solution and is a product of a shape factor and hydrodynamic volume. The observed enhancement of Huggins coefficient for short chain and branched polymer is satisfactorily interpreted by the concept of self-association. The concept of self-association allows us to predict the existence of a boundary concentration C-s(dynamic contact concentration) which divides the dilute polymer solution into two regions.

关键词： self-association polymer solution viscosity concentration dependence

Facile one-pot sonochemical synthesis of hydrophilic ultrasmall LaF3:Ce,Tb nanoparticles with green luminescence

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Progress in Natural science:materials International 2012年第5期22卷 488-492页

作者： Lisha Zhang a,Wei Li b,Xianghua Hu b,Yanlin Peng b,Junqing Hu b,Xingyu Kuang b,Linlin Song b,Zhigang Chen b a State Key Laboratory for Modification of Chemical Fibers and Polymer materials,college of Environmental science and engineering,donghua university,shanghai 201620,china b college of materials science and engineering,donghua university,shanghai 201620,china [a] State Key Laboratory for Modification of Chemical Fibers and Polymer materials College of Environmental Science and Engineering Donghua University Shanghai 201620 China [b] college of materials science and engineering Donghua University Shanghai 201620 China

Rare earth nanoparticles(RENPs) have great superiority as luminescent materials for broad applications,and a prerequisite for most of their application is to obtain hydrophilic RENPs with efficient luminescence and small diameter(254 nm UV excitation,the aqueous dispersion of LaF3:Ce,Tb nanoparticles exhibits strong green emission with luminescent quantum yield of 50%.This work probably contributes to not only the fundamental research of shape-controlled LaF3:Ce,Tb nanoparticles but also new methods of producing other RENPs for broad applications.

关键词： Sonochemical synthesis LaF3:Ce,Tb Nanoparticles Luminescence

Solvothermal synthesis of Co1-xNixFe2O4 nanoparticles and its application in ammonia vapors detection

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Progress in Natural science:materials International 2012年第1期22卷 53-58页

作者： Ya Tang a,b,Xinwei Wang a,Qinghong Zhang b,Yaogang Li a,n,Hongzhi Wang b a State Key Laboratory for Modification of Chemical Fibers and Polymer materials,donghua university,shanghai 201620,People’s Republic of china b college of materials science and engineering,donghua university,shanghai 201620,People’s Republic of china [a] State Key Laboratory for Modification of Chemical Fibers and Polymer materials Donghua University Shanghai 201620 People's Republic of China [b] college of materials science and engineering Donghua University Shanghai 201620 People's Republic of China

Magnetic Co1-xNixFe2O4 nanoparticles(NPs) were successfully synthesized via a solvothermal method using ethylene glycol as *** samples were characterized by X-ray diffraction(XRD),field emission scanning electron microscopy(FESEM),transmission electron microscopy(TEM),vibrating sample magnetometry(VSM) and gas sensing *** experimental results showed that the magnetic Co1-xNixFe2O4 NPs were composed of single phase spinel structure and the average crystallite size in the NPs is between 5.8 and 9.8 nm;the NPs are spherical with an average particle size of about 40-90 nm;the saturation magnetization(Ms) of the Co1-xNixFe2O4 NPs decreased linearly as the contents of Ni2t increased;and the as-prepared Co1-xNixFe2O4 NPs have a higher selectivity toward ammonia vapors and the Co0.8Ni0.2Fe2O4 has the best gas sensitivity of Co1-xNixFe2O4(0rxr1) NPs at working voltage of 8 V.

关键词： Magnetic materials Nanostructures Chemical synthesis Magnetic properties Gas sensing properties

Synthesis of core-shell acrylic-polyurethane hybrid latex as binder of aqueous pigment inks for digital inkjet printing

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Progress in Natural science:materials International 2012年第1期22卷 71-78页

作者： Jingfang Zhang a,Xuefeng Li a,Xinhao Shi a,Mei Hua a,Xingping Zhou b,Xiaqin Wang a,a State Key Laboratory for Modification of Chemical Fibers and Polymer materials,donghua university,shanghai 201620,china b college of Chemical engineering and Biotechnology,donghua university,shanghai 201620,china [a] State Key Laboratory for Modification of Chemical Fibers and Polymer materials Donghua University Shanghai 201620 China [b] college of Chemical engineering and Biotechnology Donghua University Shanghai 201620 China

Acrylic-polyurethane(PUA) hybrid aqueous emulsion with core-shell structure was prepared via semibatch emulsion copolymerization of the acrylate monomers(AC) in the presence of a commercial polyurethane dispersion as *** core-shell structure of the emulsion was observed by *** particle size and distribution of the emulsion was found to vary drastically with the core-shell *** thermal response properties of emulsion films were measured by DSC,and the results indicated the good compatibility between PA and PU moieties in PUA *** chemical structures of emulsion films were studied by FTIR,and the surface properties were tested by contact angle *** results supported the idea that the surface of the cast films was rich in polyurethane *** water resistance of the cast films became better by increasing the AC *** rheological properties of the latex and its utilization as a binder for aqueous pigment inks of digital inkjet printing were thoroughly investigated,indicating that the prepared hybrid emulsion could be used safely for aqueous pigment inks of digital ink jet printing.

关键词： Core-shell structure PUA hybrid emulsion Latex ink binder Rheological properties

Dynamic Mechanical Behaviour of Ultra-high Performance Fiber Reinforced Concretes

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Journal of Wuhan university of Technology(materials science) 2008年第6期23卷 938-945页

作者：赖建中 Department of materials science & engineering Nanjing University of Science & Technology

Ultra-high performance fiber reinforced concretes （UHPFRC） were prepared by replacing 60% of cement with ultra-fine industrial waste powder. The dynamic mechanical behaviour of UHPFRC with different fiber volume fraction was researched on repeated compressive impact in four kinds of impact modes through split Hopkinson pressure bar （SHPB）. The experimental results show that the peak stress and elastic modulus decrease and the strain rate and peak strain increase gradually with the increasing of impact times. The initial material damage increases and the peak stress of the specimen decreases from the second impact with the increasing of the initial incident wave. Standard strength on repeated impact is defined to compare the ability of resistance against repeated impact among different materials. The rate of reduction of standard strength is decreased by fiber reinforcement under repeated impact. The material damage is reduced and the ability of repeated impact resistance of UHPFRC is improved with the increasing of fiber volume fraction.

关键词： ultra-high performance fiber reinforced concretes split Hopkinson pressurebar dynamic repeated impact

Study on BaTiO_3 films prepared by AC power microarc oxidation

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science china(Technological sciences) 2009年第8期52卷 2195-2199页

作者： HUANG WenBo, LI WenFang & HAN Bing college of material science and engineering, South china university of Technology, Guangzhou 510640, china 1. college of material science and engineering South China University of Technology Guangzhou 510640 China

BaTiO3 films were prepared by microarc oxidation (MAO) with an in-house built alternating current (AC) power supply in Ba(OH)2 solution in this study. The surface morphology, combinability with the substrate and phase composition of the films were investigated by XRD, SEM and TEM. The BaTiO3 films were annealed at a temperature range of 900 to 1200℃ and phase compositions were tested thereafter. The results showed that the BaTiO3 films were mainly composed of the primitive hexagonal phase with relatively small amount of tetragonal and amorphous phases. Moreover, the amount of amorphous phase decreased with the time of annealing. The transformation of BaTiO3 from hexagonal structure to tetragonal stucture became obvious until the annealing temperature reached 1200℃. The film consisted mainly of BaTiO3 tetragonal structure with ferroelectric property. The influence of annealing on surface morphology and mechanism of phase transformation of the films were also discussed.

关键词： microarc oxidation ferroelectric film BaTiO3 annealing phase composition

A geometrical and physical nonlinear finite element model for spatial thin-walled beams with arbitrary section

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science china(Technological sciences) 2010年第3期53卷 829-838页

作者： YANG QingShan 1 &WANG XiaoFeng 2 1 School of Civil engineering,Beijing Jiaotong university,Beijing 100044,china 2.college of Civil engineering,Tongji university,shanghai 200092,china 1. School of Civil engineering Beijing Jiaotong University Beijing 100044 China2. College of Civil Engineering Tongji University Shanghai 200092 China

Based on the theories of Bernoulli-Euler beams and Vlasov's thin-walled members,a new geometrical and physical nonlinear beam element model is developed by applying an interior node in the element and independent interpolations on bending angles and warp,in which factors such as traverse shear deformation,torsional shear deformation and their coupling,coupling of flexure and torsion,and second shear stress are all ***,geometrical nonlinear strain in total Lagarange(TL) and the corresponding stiffness matrix are *** plastic model is applied to physical nonlinearity to comply with the yield rule of Von Mises and incremental relationship of *** stiffness matrix is derived by numerical integration on the basis of the finite segment *** show that the developed model is feasible in analysis of thin-walled structures with high accuracy.

关键词： Spatial beams thin-walled structures geometrical and physical nonlinearity finite element arbitrary section