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Nanoscale control of silks for regular hydroxyapatite formation

Progress in Natural science:Materials International 2012年第2期22卷 115-119页

作者： Xingliang He a,Xiaowei Huang b,Qiang Lu b,Shuling Bai a,Hesun Zhu c a college of Basic medical science,Chinese medical university,Shenyang 110001,People’s Republic of china b National Engineering Laboratory for Modern Silk,college of Textile and Clothing Engineering,Soochow university,Suzhou 215123,People’s Republic of china c Research Center of Materials science,Beijing Institute of technology,Beijing 100081,People’s Republic of china college of Basic medical science Chinese Medical University Shenyang 110001 People's Republic of China National Engineering Laboratory for Modern Silk College of Textile and Clothing Engineering Soochow University Suzhou 215123 People's Republic of China Research Center of Materials science Beijing Institute of Technology Beijing 100081 People's Republic of China

The control of nanoparticle shape is still a challenge for different hydroxyapatite(HA) preparation *** the present study,silk fibroin with regular nanostructures was firstly prepared and then employed to regulate the mineralization of HA *** morphology and crystal structure of the deposition were investigated by SEM,X-ray diffraction(XRD)and Fourier transform infrared spectroscopy(FTIR).Compared to previous studies in which silk fibroin with different nanostructures was used as template,the present study revealed that the HA nanoparticle shape could be controlled through regulating the nanostructure of silk *** silk nanospheres as template,the shape of HA gradually changed from pin-like structure to rice-like structure following the increase of silk fibroin *** some HA nanofibers were prepared with short silk nanofibers as *** results indicated that it is feasible to achieve the shape control of HA nanoparticles through further regulating the nanostructure of silk fibroin template,which would greatly facilitate the application of HA in different fields.

关键词： Silk fibroin Hydroxyapatite Shape control Biomineralization

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PMMR:A Method for Masking Repeats in DNA Fragment Assembly

PMMR:A Method for Masking Repeats in DNA Fragment Assembly

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2009 Asia-Pacific Conference on Information Processing

作者： Kui Cai Department of Economy and Management wuhan university of technology Huaxia college wuhan Hubei 430223 china Jincai Yang Department of Computer science huazhong Normal university wuhan Hubei 430079 china

A method named PMMR（previously merging for masking repeats）is proposed in this paper for masking repeats in DNA fragment *** method firstly identifies and counts the fragments induding a same k-mer substring by scanning the shotgun data ***,it merges these fragments by the same k-mer *** on merging the method can not only mark the position of the repeats,but also reduce the scale of shotgun data *** computer simulations show that the rate of repeats recognition is enhanced in this method,and the CPU time of DNA fragment assembly will be reduced.

关键词： previously merging k-mer substring masking repeats fragment assembly

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Preparation of Sn-doped In_2O_3 nanopowders by a solvothermal process

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Rare Metals 2008年第1期27卷 27-31页

作者： GU Yingying QIN Liping School of Chemistry and Chemical Engineering Central South University Changsha 410083 China science and technology Department Guangxi University ofTectmology Liuzhou 545006 China

Sn-doped In2O3（ITO） nanopowders in square shape were prepared in ethylene solvent by a solvothermal process,using In（4N） and SnCl4·5H2O as starting *** effects of solvothermal temperature and coprecipitation pH on the products were investigated using XRD,XPS,and *** of InOOH crystals and In4Sn3O12 crystals were prepared at 210°C or 230°C and ITO nanopowders with cubic structure were obtained at 250°C or above 250°*** the coprecipitation pH was 6,the product was ITO with impurity *** the pH was 9,the product was single phase ITO.

关键词： composite material ITO solvothermal process square shape

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Role of Hedgehog signaling pathway inproliferation and invasiveness of Hepatocellular carcinoma cells

Role of Hedgehog signaling pathway inproliferation and invas...

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全国第2届中西医结合传染病学术会议暨国家中医药管理局第1届传染病协作组会议

作者： Wei-Ting Cheng,Kai Xu~(2*),De-Ying Tian~1,Zheng-Gang Zhang~1,Li-Jiang Liu~3,Ying Chen~3 1 Department of Infectious Diseases,2 Department of orthopaedics,tongji hospital,tongji medical college,huazhong university of science and technology,wuhan 430030,china 3 Department of Pathology,School of Medicine,Jianghan university,wuhan 430056,china

The Hedgehog(Hh) pathway has been confirmed a contributor to the carcinogenesis and progression of various tumor *** investigate the Hh signaling activity in human hepatocellular carcinoma(HCC),we detected the expression levels of Hh pathway components(Shh,Ptch1 and Gli2) in 57 samples of HCC and corresponding adjacent-tumor liver *** was found that Hh pathway overexpressed in cancerous tissues compared with non-cancerous tissues and correlated closely with histologic differentiation and portal venous invasion of *** elucidate the relationship between Hh signaling and HCC progression,we took a further study in ***,the expression levels of the signaling way were detected in a subset of hepatoma cell lines and SMMC-7721 cells were selected with high level of Hh signaling ***,we employed KAAD-cyclopamine(a specific inhibitor of Hedgehog pathway) to block Hh pathway in SMMC-7721 cells and assessed the changes of their biological *** results shown that blockade of Hh signaling pathway by KAAD-cyclopamine not only induce reduction of DNA synthesis leading to marked cell growth inhibition but also cause significant attenuation in invasiveness and motility of HCC ***,our data demonstrated that Hh pathway play an important role in HCC development and ***-cyclopamine blocking Hh pathway may be a new target of new therapeutic strategy for HCC.

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Synthesis of vertically aligned carbon nanotube arrays on silicon substrates

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science china(Technological sciences) 2004年第5期47卷 616-624页

作者： ZHENG Ruiting1, CHENG Guoan1, PENG Yibin1, 2, ZHAO Yong1, 3, LIU Huaping1 & LIANG Changlin1 1. Key Laboratory of Radiation Beam technology and Materials Modification of Ministry of Education, Department of Materials science and Engineering, Beijing Normal university, Beijing 100875, china 2. School of science, Civil Aviation university of china, Tianjin 300300, china 3. Department of Physics, Nanchang university, Nanchang 330047, china Correspondence should be addressed to Zheng Ruiting Key Laboratory of Radiation Beam technology and Materials Modification of Ministry of Education Department of Materials Science and Engineering Beijing Normal University Beijing China School of science Civil Aviation University of China Tianjin China Department of Physics Nanchang University Nanchang China

The growth of well-aligned carbon nanotube (CNT) arrays using a heat chemical vapor deposition system on silicon substrates is reported. The growth properties of CNT arrays are studied as a function of synthesis conditions. It is found that 750°C and 10 nm Fe film are suitable conditions for the growth of well-aligned CNT arrays. CNT arrays with a uniform diameter, thick tube wall and firm cohesion to the Si substrate can be grown for C2H2 concentration of 27%. Based on the experiment, the processes of improving the alignment of CNT arrays and cohesion between CNT arrays and Si substrates are discussed.

关键词： carbon nanotubes, vertically aligned, silicon substrate, chemical vapor deposition.

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The relative generalized Hamming weight and the semilinear equivalence of codes

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science china(Information sciences) 2011年第4期54卷 787-794页

作者： LIU ZiHui 1 & WANG Jie 2 1 Department of Mathematics,Beijing Institute of technology,Beijing 100081,china 2 School of Mathematical sciences,Beijing university,Beijing 100871,china Department of Mathematics Beijing Institute of Technology Beijing China School of Mathematical sciences Beijing University Beijing China

Certain equivalent conditions are given for the semilinear equivalence of linear codes by using the relative generalized Hamming weight and the value function.

关键词： value function semilinear equivalence support weight relative generalized Hamming weight

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A New Method of Building Grey Forecasting Model

A New Method of Building Grey Forecasting Model

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2009中国控制与决策会议

作者： Xiangyan Zeng~1,Xinping Xiao~2 1.college of Mathematics and Computational science,Guilin university of Electronic technology,Guilin 541004 2.college of science,wuhan university of technology,wuhan 430063,china

＜正＞Based on the modeling mechanism,the background value of accumulating method GM（1,1） model is reestablished,and its forecasting formula changed from white respond to connotation *** theoretical analysis indicates that the improved modeling method extends the significative region of the ***,results of the followed simulated test and the applied examples show that the new modeling method is suitable for either low-growth series or high-growth series,and has a very high precision for both short-term and long-term *** extends the applicable range of GM（1,1）.

关键词： GM(1 1) model Accumulating method Background value White respond Connotation type

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现代颌面创伤救治的临床研究

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华中科技大学学报（医学版） 2002年第3期31卷 324-326页

作者：陶学金吴丽娟马净植陈卫民华中科技大学同济医学院附属同济医院口腔医学中心武汉430030

通过对 1997年 5月～ 2 0 0 0年 10月收治的 12 1例颌面创伤患者 (其中 2 3例伴有颅脑及其它脏器的损伤 )救治的分析。指出颌面创伤应提倡“协同治疗”,科室之间分工明确 ,迅速对患者全身情况作出诊断。骨折的治疗宜采用坚强内固定术 ,... 详细信息

通过对 1997年 5月～ 2 0 0 0年 10月收治的 12 1例颌面创伤患者 (其中 2 3例伴有颅脑及其它脏器的损伤 )救治的分析。指出颌面创伤应提倡“协同治疗”,科室之间分工明确 ,迅速对患者全身情况作出诊断。骨折的治疗宜采用坚强内固定术 ,或将坚强内固定术与颌间结扎结合起来 ,以提高疗效 ,缩短治疗周期。采用先进计算机技术 ,对骨折部位行三维影像重建 ,可利于术前制订手术方案。术中采用整形外科技术 ,能减少术后畸形 ,提高治疗效果。经过治疗 ,除 2例患者未行手术外。

关键词：颌面创伤坚强内固定协同治疗三维影像重建治疗临床研究

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Synthesis, Crystal Structures and Catalysis of Dinuclear Cd(Ⅱ) Complexes Bridged by Unusual (N,O,O′)-Coordinated α-Amino Acids

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Chemical Research in Chinese Universities 2012年第1期28卷 73-78页

作者： DENG Dong-sheng1,2, WANG Li1, PEI Ya-mei1, FENG Lu2 and LIU Chang-lin1 1. Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, School of Chemistry, Central china Normal university, wuhan 430079, P. R. china 2. college of Chemistry and Chemical Engineering, Luoyang Normal university, Luoyang 471022, P. R. china School of Chemistry Central China Normal University Key Laboratory of Pesticide & Chemical Biology Ministry of Education Wuhan 430079 college of Chemistry and Chemical Engineering Luoyang Normal University Luoyang 471022

Four dinuclear amino acid cadmium（II） complexes [Cd2（tren）2（dl-alaninato）]（ClO4）3·H2O（I）, [Cd2（tren）2· （l-alaninato）]（ClO4）3·H2O（II）, [Cd2（tren）2（dl-phenylalaninato）]（ClO4）3（III） and [Cd2（tren）2（l-phenylalaninato）]· （ClO4）3（IV）, constructed from mixed ligands of tris（2-aminoethyl）amine（tren） and racemic or natural amino ac ids（amino acids=dl or l-alanine, and dl or l-phenylalanine）, have been synthesized and characterized by X-ray crys tallography. The structural analysis of complexes I and III reveals that the cadmium centers are coordinated by one tren ligand and one amino acid molecule with the unusual （N,O,O′）-bridged mode, resulting in asymmetric chromo phores of CdN4O and CdN5O in complex I, CdN4O2 and CdN5O in complex III, respectively. The utility of the four complexes as efficient water-compatible Lewis acid catalysts for the direct aldol reaction in water was examined. The reaction proceeded smoothly to afford the corresponding β-hydroxy ketones in up to 99% yield. Moreover, the dias tereoselectivity of the reaction favors the formation of the syn-isomers.

关键词： Dinuclear cadmium(II) complex Amino acid Aldol reaction

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Design of the Urban Land Grading Information System

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Geo-Spatial Information science 2002年第3期5卷 26-32页

作者： LIU Yaolin ZHANG Yumeiprofessor,School of Resource and Environment science,wuhan university,129 Luoyu Road,wuhan 430079,china. School of Resource and Environment science Wuhan University Wuhan China

This paper discusses the urban land grading system based on the self_developed GIS *** system establishes the system template,the relevant data structure and the empirical formulas of the affecting factor and economic data of land ***,the system can calculate the service radius,sum and land grade ***,it can do statistics and query on various land information and show the result of land grading with spatial and attribute *** paper illustrates the result by giving an example of the commercial land grading of the urban area of wuhan City by the urban land grading system.

关键词： GIS urban land grading information system

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