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Optimization study on the rehydration process of lyophilized human platelets

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Science Bulletin 2011年第Z1期 455-460页

作者： FAN JuLi1,2,XU XianGuo3,4,ZHANG ShaoZhi2,XU MengJie2,ZHU FaMing3,4 & CHEN GuangMing2 1 Department of Man-machine and Environment Engineering,Nanjing university of Aeronautics and Astronautics,Nanjing 210016,China 2 Institute of Refrigeration and Cryogenics,Zhejiang university,Hangzhou 310027,China 3 Blood center of Zhejiang Province,Hangzhou 310006,China 4 Key Laboratory of Blood Safety research,Ministry of Health,Hangzhou 310006,China

Long-term preservation of human platelets will greatly reduce the risk of their shortage. Lyophilization has been proved feasible for this purpose. For the recovery of lyophilized platelets,rehydration is an important process. In this paper,the rehydration proc-esses for 1 mL and 2 mL samples were studied. The effects of prehydration duration(15,30,60,90,120 and 150 min) in 37°C water vapor and the concentration of rehydration solution(25%,50%,75%,100% platelet-poor plasma) on the recovery rate,MPV(mean platelet volume) and PDW(platelet distribution width) were investigated. The mass changes during the prehydration process were weighed. The optimized rehydration conditions are as follows:(1) for 1 mL sample,the prehydration duration was 15 min and for 2 mL sample the prehydration duration was 90 min;(2) the rehydration solution was 75% platelet-poor plasma. Under optimized conditions,the morphology of the rehydrated platelets kept normal and their ultrastructures kept intact,their aggregation capacity to thrombin(1 U/mL) was 82.8% of the fresh ones. These results will be helpful for designing the freeze-drying protocols for human platelets.

关键词： lyophilization human platelets prehydration rehydration solution morphology aggregation function

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协同仿真运行管理平台研究与实现

系统仿真学报 2002年第5期14卷 584-587页

作者：王江云王行仁柴旭东北京航空航天大学先进仿真技术航空科技重点实验室北京100083 清华大学CIMS中心北京100084

研究协同仿真运行管理平台的设计和实现。协同仿真平台支持异地建模、分布仿真、支持不同仿真工具之间的互操作。协同仿真运行管理平台是协同仿真平台的一部分,具有仿真运行管理、仿真时间管理、仿真数据管理等功能。本文探讨了运行管... 详细信息

研究协同仿真运行管理平台的设计和实现。协同仿真平台支持异地建模、分布仿真、支持不同仿真工具之间的互操作。协同仿真运行管理平台是协同仿真平台的一部分,具有仿真运行管理、仿真时间管理、仿真数据管理等功能。本文探讨了运行管理平台的实现机理,最后介绍了一个应用实例。

关键词：分布仿真仿真互操作计算机仿真协同仿真运行管理平台

Model Predictive Control with Missing Data

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Model Predictive Control with Missing Data

第二十七届中国控制会议

作者： Huang Chongji1,Gao Huijun1,Shi Peng2 1.Space Control and Inertial Technology research center,Harbin Institute of Technology,Harbin 150001,P.R.China 2.Faculty of advanced Technology,university of Glamorgan,Pontypridd,CF37 1DL,United Kingdom

This paper is concerned with the problem of robust model predictive control for discrete-time systems with packet losses.A stochastic process satisfying Bernoulli random binary distribution is utilized to model the packet losses,and a parameter dependent Lyapunov function is adopted to reduce the *** aim is to design a state feedback controller which minimizes an upper bound on a quadratic objective function at each sampling instant for all admissible packet losses and system parameter uncertainties,and the robust stochastic stability of the closed-loop system is *** hard constraints on the variances of the inputs and outputs are also *** the conditions to solve the proposed problem are formulated in the framework of linear matrix inequalities（LMIs） .A simulation example is given to illustrate the effectiveness of the proposed control methodology.

关键词： Model predictive control Packet losses Parameter dependent Lyapunov function Stochastic stability

Ponderation on Teaching Faculty Construction of Independent College

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Ponderation on Teaching Faculty Construction of Independent ...

2010 International Conference on Optics, Photonics and Energy Engineering (OPEE 2010)

作者： Chaoying Liu1,2 Zhihua Zhao1 1 Hebei university of Science and Technology Shijiazhuang,China 2 Faculty of advanced Technology university of Glamorgan Pontypridd CF37 1DL,United Kingdom Zheying Song1,2 Xueling Song1,2 1 Hebei university of Science and Technology Shijiazhuang,China 2 Faculty of advanced Technology university of Glamorgan Pontypridd CF37 1DL,United Kingdom

As the enrollment expansion of Independent College,the demand for teachers has increased *** the analysis of the characters of the students,cultivation purpose and the teaching faculty construction as the point of departure,this paper focuses on analyzing the problem existed in the teaching team construction in Independent College,and some improvement measures are proposed for teaching faculty construction according to the main problem.

关键词： Independent College Teaching faculty construction application talents cultivation

Recurrence and metastasis of hepatocellular carcinoma: progress and prospects

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Hepatobiliary & Pancreatic Diseases International 2002年第1期1卷 35-41页

作者： Xin-Da Zhou From the Liver Cancer Institute, Zhong Shan Hospital, Fudan university Medical center, Shanghai 200032, China Liver Cancer Institute Zhong Shan Hospital Fudan University Medical Center Shanghai 200032 China. xdzhou2000@***

Background: Recurrence after resection of hepatocellu-lar carcinoma(HCC) is a major obstacle to improveprognosis. Therefore, further improvement of long-term survival may depend on prevention and treat-ment of the recurrent ***: To evaluate the progress of surgery forHCC, the risk factors for recurrence, and clinical andbasic studies on the prevention and management of re-currence and metastasis after resection of *** sources: A review of currently available data inthe mentioned *** synthesis: Encouraging changes in the prognosticpattern were observed when the primary liver cancer(PLC) data of 1958-1967 (n=118), 1968-1977 (n=356), 1978-1987(n=715) and 1988-1997 (n=2038)were compared. The 5-year survival was 2.8%, 7.3%,27.1% and 52.5%, respectively, and the 10-yearsurvival 2.8%, 4.3%, 19.8% and 39.9%, respective-ly. Risk factors for recurrence included symptomaticpatient, high γ-glutamyl-peptidase (γ-PGT), largetumor size, portal vein embolus, advanced tumorstage, etc. Active hepatitis activity in the nontumorousliver and perioperative transfusion enhanced the re-currence. Molecular research into the invasiveness ofHCC identified some factors positively related to inva-siveness: p16 and p53 mutation, H-ras, c-cerbB2,mdm2, transforming growth factor (TGF), epidermalgrowth factor receptor (EGF-R), matrix metallopro-teinase-2 (MMP-2), urokinasetype plasminogen acti-vator (uPA), its receptor (uPA-R) and inhibitor(PAI-1), intercellular adhesion molecule-1 (ICAM-1), vascular endothelial growth factor (VEGF),platelet-derived endothelial cell growth factor (PD-ECGF), and basic fibroblast growth factor (bFGF).In contrast, some factors were negatively related toHCC invasiveness: nm23-H1, Kai-1, tissue inhibitor ofmetalloproteinase-2 (TIMP-2), integrin 5, and E-cadherin. Re-resection of subclinical recurrence yield-ed a 5-year survival of 56.0% calculated from the firstresection (n=202) .Postoperative transarterialchemoembolization (TACE, n=103), hepatic

关键词： hepatocellular carcinoma resection recurrence tumor invasiveness prognosis

Local Microstructrue and Infrared Emission of Er-doped 12CaO·7AL2o3 Powder

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Local Microstructrue and Infrared Emission of Er-doped 12CaO...

第11届全国发光学学术会议

作者： D.Wang Y.X.Liu~* Y.C.Liu C.S.Xu C.L.Shao X.H.Li (center for advanced Opto-electronic Functional Material research,Northeast Normal university,5268 Renmin street.Changchun 130024,People’s Republic of China )

Erbium-doped semiconductor or insulators have attracted intense interest over recent years for the application of Er doped fiber amplifiers(EDFA)in integrated optoelectronic and telecommunication fields due to their 1.54 ***,rare-earth-doping in C 12A7 powder has been rarely investigated till *** this paper,wide band gap material 12CaO·7AlO(Cl2A7) with wide-band-gap of 5.9 eV was used as host for Er *** incorporation in Cl2A7 powder could enable hybrid integration with a variety of optically inactive materials.

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一种用于信息安全的信息保障模型

四川大学学报（工程科学版） 2004年第4期36卷 103-106页

作者：陈炜罗霄峰罗万伯 center for advanced research in Biotechnology Univ. of Maryland Biotechnology Inst. 四川大学计算机学院四川成都610064

将一种信息安全(INFOSEC)模型扩展成为一个信息保障(IA)模型,用于指导信息安全研究、工程和教育。新模型包括四维度量:安全目标,信息流状态,安全保障,时间。将信息安全的保护范畴扩大到信息资产,并对可用性、完整性和机密性重新进行了定... 详细信息

将一种信息安全(INFOSEC)模型扩展成为一个信息保障(IA)模型,用于指导信息安全研究、工程和教育。新模型包括四维度量:安全目标,信息流状态,安全保障,时间。将信息安全的保护范畴扩大到信息资产,并对可用性、完整性和机密性重新进行了定义,增加了新内涵;采用深度防御概念,在注重技术的同时,突出了人的因素,并强调了安全管理在系统生命期重要作用。时间维的引入,使该模型真正成为动态模型。

关键词：信息安全信息资产信息保障信息安全模型安全管理

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中日近代化之制度模仿比较

武汉大学学报（人文科学版） 2004年第5期57卷 556-562页

作者：袁艳胡汉昌武汉大学新闻与传播学院湖北武汉430072 武汉大学经济发展研究中心湖北武汉430072

面对西方的冲击,近代中国对西方的制度模仿经历了始为"中体西用"、后则"全盘西化"的两个错误极端,而日本则走了一条结合本国实情、避开先进国已走过的弯路、做到近代化而不同化的近代化成功道路。对制度模仿的不同态度和做法,导致了截... 详细信息

面对西方的冲击,近代中国对西方的制度模仿经历了始为"中体西用"、后则"全盘西化"的两个错误极端,而日本则走了一条结合本国实情、避开先进国已走过的弯路、做到近代化而不同化的近代化成功道路。对制度模仿的不同态度和做法,导致了截然不同的近代化结果。

关键词：近代化制度模仿制度后发优势

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古中国的契约观念——以唐、宋为中心

法制与社会发展 2008年第2期14卷 52-61页

作者：张姗姗吉林大学理论法学研究中心吉林长春130012

对于古中国而言,刑事法律制度的发达程度要远远高于民事法律制度。但人们不可回避的一个问题是:一个人可以一生与刑事法律关系没有交点,但他不可能一生与民事法律关系没有联系。而对于民事法律制度而言,契约则是一个不可回避的、折射着... 详细信息

对于古中国而言,刑事法律制度的发达程度要远远高于民事法律制度。但人们不可回避的一个问题是:一个人可以一生与刑事法律关系没有交点,但他不可能一生与民事法律关系没有联系。而对于民事法律制度而言,契约则是一个不可回避的、折射着人类文明进步之光的概念。古中国契约法律制度和契约实践中,契约观念表现为契约自由、同情弱者以及对契约的认可和重视。

关键词：契约观念契约自由同情弱者对契约的认可和重视