检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

Dacryology in china

眼科学报 1998年第1期14卷 1-8页

作者： Hancheng Zhang, Zhulian Zhou, Zhuo Chen, Yi Wu, Qi Zhangcenter of Dacryology, Second Affiliated Hospital of Ist Military Medical University, guangzhou 5102.2.{2. Zhougshan Ophthalmic center, guangzhou 510060,{2. center of Dacryology Second Affiliated Hospital of Ist Military Medical University Guangzhou 510282 China

Purpose: International Society of Dacryology held the IV International Congress in Stock -hohm on June 1996. I was warmly invited as a guest of honor beforehand to deliver a lecture on a special topic of 'Dacryology in china' there, so that the world might understand the dacryology in china, and thus the international growth of dacryology as a discipline would be ***: In china tear lab research and clinical research of LG are nearly empty except a few papers published. We had studied 3 items on LS for 2. years before 1979, and put our attention mainly on dacryology since 1979 by 3 stages: (1) collecting literatures( 1979-81) ; (2. lab research(1981-84) and (3) clinical research, put DE as the key point by 4 steps: DE diagnosis(1984-86); DE treatment (1987-91); DE Condition Judgement(1989-92. & DE cause & mechanism( 1991-95).Results: In the past 44 years, esp. from 1979 on, in a planned way, we have systematically researched the dacryology with main results below; created new word 'Leiyexue'

关键词：泪腺系统泪囊眼干涩

在线全文

学校读者我要写书评

暂无评论

隔震层位置与隔震支座选型

世界地震工程 2010年第1期26卷 105-108页

作者：徐忠根周福霖马玉宏广州大学土木工程学院广东广州510006 广州大学工程抗震研究中心广东广州510405

探讨隔震层的竖向设计位置,以期优化隔震设计,促进隔震技术的发展。隔震层设置在±0.00地板下和地下室板底相比:(1)在单层地下室部分不需设置隔震支座;(2.因减少地下室层的竖向荷载,竖向承载力的要求容易得到满足;(3)对于平面极不规则... 详细信息

探讨隔震层的竖向设计位置,以期优化隔震设计,促进隔震技术的发展。隔震层设置在±0.00地板下和地下室板底相比:(1)在单层地下室部分不需设置隔震支座;(2.因减少地下室层的竖向荷载,竖向承载力的要求容易得到满足;(3)对于平面极不规则的结构,在±0.00板底隔震时,可以把上部结构分成几个平面相对比较规则的部分,因而隔震层扭转影响引起的位移可以减小;(4)对于文中算例,由于此3方面的原因,隔震支座选型后当隔震层处于±0.00地板下时可以降低隔震支座的费用达37.4%。对于平面尺寸大、平面极不规则的建筑结构把上部结构分割成若干规整的结构在首层地面以下进行隔震是一种经济可行的隔震方案。

关键词：隔震层位置扭转影响位移平面规则性隔震支座

IL-1beta sensitizes rat intervertebral disc cells to Fas ligand mediated apoptosis in vitro

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2007年第10期28卷 1671-1676页

作者： Li-yang CUI~2.Shang-li LIU~(2.4),Yue DING~2.Dong-sheng HUANG~2.Ruo-fan MA~2.Wei-guo HUANG~2.Bao-shan HU~2.Qiu-hui PAN~3~2.Department of Orthopaedic Surgery and ~3 Department of Lin Bai-Xin Medical research center,the Second Affiliated Hospital of Sun Yat-SenUniversity {2. 51012.,china ment of Orthopaedic Surgery the Second Affiliated Hospital of Sun Yat-Sen University Guangzhou 510120 China. gzxy168@***.

Aim:To determine the apoptotic effect of recombinant rat Fas Ligand on rat inter-vertebral disc cells pre-treated with IL-1beta in vitro,and the expression of Fas incultured rat intervertebral disc ***:Cells were isolated from the innerannulus fibrosus and transition zones of lumbar discs from Sprague-Dawley *** cells were grown in monolayer and divided in 5 treatment ***-1 beta (10ng/mL),FasL (5,2. ng/mL) with/without IL-1beta (10 ng/mL) pre-treatment wasrespectively added in Dulbecco’s modified Eagle’s medium and Ham’s F-12.me-dium with 1% fetal bovine *** 32.h,the cells were stained with annexin V-FITC and propidium iodide to evaluate apoptosis using flow cytometry and toanalysis transcription of Fas using ***:Compared with controlgroup,FasL (2. ng/mL),IL-1β(10 ng/mL)+FasL (5 ng/mL),and IL-1β(10 ng/mL)+FasL (2. ng/mL) induced significant apoptosis of the disc cells (P0.05).IL-1β(10 ng/mL) enhanced the apoptosis-inducing effects of FasL (5 ng/mL) and FasL (2. ng/mL) in disc *** genetranscription in all groups and Fas expression in the 5 treatment groups wereapproximately 1.2.2.1-fold greater than control group (respectively,P<0.05).Additionally,Fas expression in FasL with IL-1β pre-treatment groups were signifi-cantly up-regulated than in FasL groups (P<0.01).Conclusion:The results of thisstudy showed disc cells pre-treated with IL-lbeta increased apoptotic rate inresponse to FasL in vitro and provided insights to understand Fas/FasL system-mediated apoptosis in disc cells which would be enhanced due to inflammationfactor in degenerative disc.

关键词： intervertebral disc cell apoptosis Fas ligand flow cytometry interleukin-1 beta

Non-cytolytic antigen clearance in DNA-vaccinated mice with electroporation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2007年第7期28卷 1024-1030页

作者： Jin-liang PENG~(2.5),Yong-gang ZHAO~(2.5),Jun-hua MAI~2.Wen-ka PANG~2.Wei GUO~2.Guang-ming CHEN~4,Guo-yu MO~4,Gui-rong RAO~4,Yu-hong XU~(2.3,6)Schools of ~2.Life Sciences and Technology and ~3 Pharmacy,Shanghai Jiao Tong University,Shanghai 2.02.0,china ~4 people's LiberationArmy's Liver Disease research {2.,458 Hospital of People's Liberation Army.guangzhou 510400,china Schools of Life Sciences and Technology Shanghai Jiao Tong UniversityShanghai 200240 China. yhxu@***.

Aim:To explore the potential of electroporation （EP）-mediated hepatitis B virus（HBV） DNA vaccination for the treatment of chronic HBV ***:BALB/c mice were vaccinated with HBV DNA vaccine encoding for the HBVpreS2.S antigen,combined with or without *** surface antigen expressionplasmid was administered into mice liver via a hydrodynamic injection to mimicHBV *** clearance of antigen in the serum and liver was detected byELISA assay and immunohistochemical *** histopathology of the livertissues was examined by HE staining and serum alanine aminotransferase ***:The immunogenicity of HBV DNA vaccine encoding for the HBV preS2.S antigen can be improved by EP-mediated vaccine *** elicited immuneresponses can indeed reduce the expression of HBV surface antigen （HBsAg） inhepatocytes of the mouse model that was transfected to express HBsAg using thehydrodynamic injection *** antigen clearance process did not causesignificant toxicity to liver tissue,suggesting a non-cytolytic ***:The EP-aided DNA vaccination may have potential in mediating viralclearance in chronic hepatitis B patients.

关键词： DNA vaccine hepatitis B virus electro poration antigen clearance

A rare polymorphism of the COX7B2.gene in a Cantonese family with nasopharyngeal carcinoma

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science china(Life Sciences) 2004年第5期47卷 449-453页

作者： LIANG Hui1, CHEN Hankui1, SHEN Yayun2. FENG Qisheng1, JIN Wei2. HUANG Wei2.& ZENG Yixin1 1. Cancer center, Sun Yat-sen University, guangzhou 510060,{2. 2. Chinese National Human Genome center at Shanghai, Shanghai 2.12.3,{2. 1. Cancer center Sun Yatsen University 510060 Guangzhou China 2. Chinese National Human Genome center at Shanghai 201203 Shanghai China

Nasopharyngeal carcinoma (NPC) is the most common head and neck cancer in southern china, and the genetic susceptibility is believed to play an important role in the aetiol-ogy of this malignancy. In our previous studies, one candidate susceptibility locus has been mapped to chromosome 4p11-p14 in a subset of NPC families. In the present study, we screened the cytochrome oxidase VIIb2.(COX7B2. gene which resides in this region and investigated the relationship of single nucleotide polymorphisms (SNPs) of this gene with these familial NPC pa-tients. We identified five novel SNPs in this gene, among them -158101G>T and -15732.G>A in promoter region, -109602.>G in intron 2. 78T>A in exon 3, and 354T>A in 3?untranslational region. The change 78T>A at codon 2. which leads to CAT2.CAA (His2.Gln) was shared by patients from family 31 that carried the susceptibility haplotype, but not found in cases from other NPC families nor in sporadic cases. However, the frequency of allele A was relatively low in normal controls both from Guangdong and eastern china (0.45% and 0.2.%, respectively), and this variant was not found in pooled DNA samples from the white and the black population. Pro-tein sequence alignment showed that the 2.His of COX7B2.protein is consistent among different species. Our results suggested that the codon 2. of COX7B2.gene might be conservative during the process of evolution, and the rare variation His2.Gln was probably associated with the high risk in NPC pedigree 31.

关键词： COX7B2 gene,nasopharyngeal carcinoma,SNPs.

An Improved Finite Difference Scheme for Solving the Equation of Filtration Type in Porous Textiles with Phase Change Materials

在线全文

学校读者我要写书评

暂无评论

An Improved Finite Difference Scheme for Solving the Equatio...

2.07国际计算力学研讨会

作者： Q.Y.Zhu~(1 2.) 1 Ocean Engineering research center School of Engineering Zhongshan University {2. 5102.5 china 2.Guangdong Province Key Laboratory of Coastal Ocean Engineering Zhongshan University {2. 5102.5 china Ocean Engineering research center School of EngineeringZhongshan UniversityGuangzhou510275China Guangdong Province Key Laboratory of Coastal Ocean Engineering Zhongshan University Guangzhou 510275 China

＜正＞In this paper an improved finite difference scheme is investigated to solve the equation of filtration type in porous textiles with phase change materials（PCM）,which can be expressed as a nonlinear source term. Due to the effects of source term,the constructed scheme is total variation bounded（TVB）.On the basis of this scheme thermal buffering effect of PCM is *** distributions of the temperature,saturated degree in the porous media with PCM were numerically computed by this *** the comparison the distributions of the temperature,saturated degree in the porous media without PCM were also numerically *** results indicate that this method is satisfactory.

关键词： improved finite difference scheme porous textiles phase change material

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Rieger Syndrome

眼科学报 1998年第1期14卷 52-56页

作者： Juan Deng, Ningli WangZhongshan Ophthalmic center, Sun Yat-sen University of Medical Sciences, guangzhou 510060,{2. Zhongshan Ophthalmic center Sun Yat-sen University of Medical Sciences Guangzhou 510060 China

Purpose: To discuss the clinic features of Rieger syndrome, the reasons of making wrong diagnosis , the way of treatment, and the research progress of its molecular characterization and gene mapping of this ***: Two cases of Rieger syndrome which affected a patient and his daughter were studied. Multiple clinical examinations including photography of anterior segment, go-nioscopy and fundus, Humphrey perimetry, A-scan ultrasonography, multiple tonometry in a day and chromosome examination were performed. Most importantly, ultrasonic biomicro-scope(UBM) was first used to show the abnormalities of anterior segment in this syndrome. Results: Gonioscopic examination revealed many mesoderm tissues remained and some parts of the iris adhered to cornea . In addition to hypoplasia of cornea, iris and chamber angle, UBM showed that there was also hypoplasia of ciliary body. The result of the chomosome examination indicated ***: Rieger syndrome is an autosomal-dominated disorder with

关键词：眼病染色体异常分了生物学 Riegr综合症超生波生物显微镜 ubm

THE EVALUATION OF LEVELING CONTROL OF PADDY FIELD LEVELER BASED ON ULTRASONIC SENSORS

在线全文

学校读者我要写书评

暂无评论

THE EVALUATION OF LEVELING CONTROL OF PADDY FIELD LEVELER BA...

基于SHPB试验的钢纤维混凝土动态性能研究

亚洲精细农业与计算机农业应用联合大会

作者： Hu Lian 1 2.Luo Xiwen 1 2.Zhao Zuoxi 1 2.Li Qing 1 2.Chen Weitong 1 2.(1 Key Laboratory of Key Technology on Agricultural Machine and Equipment Ministry of Education. South china Agricultural University guangzhou 510642.{2. 2. College of Engineering South china Agricultural University guangzhou 510642.{2.

Rice growing demands quite level fields due to its special growth requirements. When a tractor travels in a paddy field, the unevenness of the ground will cause roll angles. A paddy laser leveler was developed by South china Agricultural University and the leveler features a specially leveling harrow which could turn from side to side by a cylinder. In order to estimate the leveling control system of paddy field leveler, the inclination of the harrow was measured using two SensComp 600 ultrasonic sensors. The ultrasonic sensors were fitted on the harrow’s two ends, respectively, each measuring the distance from ground, which acted as reference plane, to calculate the inclination angle. It was found that using two ultrasonic sensors would provide accurate inclination information of the harrow even when at non-right angles to the floor, and sensor in movement. The angles measured was compared with data from an attitude-heading reference system AHRS500GA-2.6 device used as a reference, the results showing that the calculated inclination was quite accurate: the maximum static-error and maximum dynamic-error were 0.08°and 1°respectively. Finally, estimation experiments were done in laboratory. Based on the evaluation results, it was concluded that the leveling control system measured inclination in real-time and precisely, the maximum error less than 1°, and the whole leveling system works reliably.

关键词： Paddy Field Leveler Ultrasonic Sensor Distance Measurement Inclination Leveling Control

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

水电能源科学 2010年第2期28卷 103-105页

作者：蒋国平焦楚杰任达广州大学工程抗震研究中心广东广州510405 广州大学土木工程学院广东广州510006

采用分形理论研究了钢纤维混凝土和素混凝土在SHPB(分离式Hopkinson压杆)试验中的裂纹特性,分析了断裂表面的分形性质与材料属性及冲击压力的关系,给出了混凝土断裂表面分形的特点,采用计盒方法(FIPS程序)计算了混凝土分形维数,建立了... 详细信息

采用分形理论研究了钢纤维混凝土和素混凝土在SHPB(分离式Hopkinson压杆)试验中的裂纹特性,分析了断裂表面的分形性质与材料属性及冲击压力的关系,给出了混凝土断裂表面分形的特点,采用计盒方法(FIPS程序)计算了混凝土分形维数,建立了损伤因子与分形维数的函数关系。结果表明,该方法为探索混凝土表面裂纹图形的分形特征与其承受的动荷载之间的内在规律、建立适合描述混凝土分形结构和分形行为的数学力学方法及基本理论寻求了新途径。

关键词：分离式Hopkinson压杆混凝土动态本构关系冲击分形