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Science China(Physics,Mechanics & Astronomy) 2007年第2期50卷 221-230页

作者： LIU Bing1,2.ZHANG Hong1,LI WenJian1,LI Qiang1,ZHOU GuangMing1,XIE Yi1,2.HAO JiFang1,MIN FengLing1,2.ZHOU QingMing1,2.& DUAN Xin1,2. Institute of Modern Physics,chinese academy of {2.,Lanzhou 730000,China 2.graduate University of chinese academy of {2.,beijing {14.,China Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000China

The combination of ionizing radiation and gene therapy has been investigated. However, there are very few reports about the combination of heavy-ion irradiation and gene therapy. To determine if the pre-exposure to low-dose heavy ion beam enhances the suppression of AdCMV-p53 on non-small lung cancer (NSLC), the cells pre-irradiated or non-irradiated were infected with 2., 4. MOI of AdCMV-p53. Survival fraction and the relative biology effect (RBE) were determined by clonogenic assay. The results showed that the proportions of p53 positive cells in 12.6+ beam induced AdCMV-p53 infected cells were more than 90%, which were signifi-cantly more than those in γ-ray induced AdCMV-p53 infected cells. The pre-exposure to low-dose 12.6+ beam significantly prevented the G0/G1 arrest and activated G2.M checkpoints. The pre-exposure to 12.6+ beam significantly improved cell to apoptosis. RBEs for the 12.6+ + AdCMV-p53 infection groups were 30%-60%, 2.%-130% and 30%-70% more than those for the 12.6+-irradiated only, AdCMV-p53 infected only, and γ-irradiation induced AdCMVp53 infected groups, respectively. The data suggested that the pre-exposure to low-dose 12.6+ beam significantly promotes exogenous p53 expression in NSLC, and the suppression of AdCMV-p53 gene therapy on NSLC.

关键词： heavy-ion beam gene therapy p53 non-small lung cancer adenoviral vector low dose

A cumulant-based parameter estimation algorithm for near-field sources

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Progress in Natural Science:Materials International 2007年第8期17卷 900-905页

作者： Liang Junli~(1,2.) Yang Shuyuan~(1,2. Zhang Junying~3 (1.Institute of Acoustics,chinese academy of {2.,beijing 100080,China 2.{4. School,chinese academy of {2.,beijing 100039,China 3.National Laboratory of Radar Signal Processing,Xidian University,Xi'an 710071,China) [a]Institute of Acoustics Chinese Academy of Sciences Beijing China [b]graduate School Chinese Academy of Sciences Beijing China [c]National Laboratary of Radar Signal Processing Xidian University Xi'an China

To efficiently use the array aperture and avoid the complicated parameter pairing computation,this paper proposes a new cumulant-based algorithm for localizing near-field narrowband ***,this algorithm proposes a symmetric uniform linear ar- ray (ULA),and constructs three cumulant matrices by using the fourth-order cumulants of some properly chosen sensor outputs;second- ly,unlike the conventional parallel factor (PARAFAC) analysis models in data or subspace domain,it forms a three-way array (TWA) in the fourth-order cumulant domain using the three matrices,and analyzes the uniqueness of its low-rank decomposition;thirdly,it jointly estimates the frequency,the direction-of-arrival (DOA),and the range of each near-field source from the matrices via the low-rank de- composition of the *** simulation results are presented to validate the performance of our proposed method.

关键词： array signal processing localization cumulant parallel factor (PARAFAC) analysis three-way array (TWA)

Terrestrial transect study on driving mechanism of vegetation changes

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Science China Earth sciences 2008年第7期51卷 984-991页

作者： ZHANG YuJin1,2.& ZHOU GuangSheng1 1 State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, chinese academy of {2., {4. 100093, China 2.{4. University of chinese academy of {2., {4. 10004., China 1. State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China 2. graduate University of chinese {2. of {4. Beijing 100049 China

In terms of chinese climate-vegetation model based on the classification of plant functional types, to- gether with climatic data from 1951 to 1980 and two future climatic scenarios (SRES-A2.and SRES-B2. in China from the highest and the lowest emission scenarios of greenhouse gases, the distribution patterns of vegetation types and their changes along the Northeast China Transect (NECT) and the North-South Transect of Eastern China (NSTEC) were simulated in order to understand the driving mechanisms of vegetation changes under climatic change. The results indicated that the vegetation distribution patterns would change significantly under future climate, and the major factors driving the vegetation changes were water and heat. However, the responses of various vegetation types to the changes in water and heat factors were obviously different. The vegetation changes were more sensi- tive to heat factors than to water factors. Thus, in the future climate warming will significantly affect vegetation distribution patterns.

关键词： driving mechanism vegetation terrestrial transect climatic change plant functional types

Report of Prionospio complex(Annelida:Polychaeta:Spio-nidae) from China's waters,with description of a new species

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Acta Oceanologica Sinica 2009年第1期28卷 116-127页

作者： ZHOU Jin LI Xinzheng Institute of Oceanology. Chinese Aeademy of Sciences Qingdao 266071 China graduate School Chinese Academy of Sciences Beijing 100039 China

Nine species of Prionospio complex are recorded from China＇s waters,including one new species and six newly recorded ***（Prionospio） pacifica ***.,is characterized by having first and forth pairs of branchiae pinnate,second and third pairs of apinnate,ventral crest on Setiger 9 and dorsal crests on Setigers *** kirrae（Wilson,1990）,Prionospio（Aquilaspio） convexa Imajima,1990,Prionospio（Minuspio） multibranchiata Berkeley,192.,Prionospio（Prionospio） bocki Sderstrm,192.,Prionospio（Prionospio） dubia Maciolek,1985 and Prionospio（Prionospio） paradisea Imajima,1990 are recorded for the first time from China＇s waters.

关键词： taxonomy Prionospio complex new species newly recorded species China's waters.

Origin of the Red Earth sequence on the northeastern Tibetan Plateau and its implications for regional aridity since the middle Miocene

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Science China Earth sciences 2006年第5期49卷 505-517页

作者： WANG Xianyan1,7, LU Huayu1,2. JI Junfeg3, WANG Xiaoyong1,7, ZHAO Jingbo4. HUANG Baochun5 & LI Zhen6 1. SKLLQG, Institute of Earth Environment, chinese academy of {2., Xi’an 710075, China 2. Department of Urban and Resources {2., Nanjing University, Nanjing 2.0093, China 3. Department of Earth {2., Nanjing University, Nanjing 2.0093, China 4. Department of Geography, Shaanxi Normal University, Xi’an 710062. China 5. Institute of Geology and Geophysics, chinese academy of {2., beijing 10002., China 6 Department of Geography, Qinghai Normal University, Xining 810008, China 7. graduate School of the chinese academy of {2., beijing 100039, China 1. SKLLQG Institute of Earth Environment Chinese Academy of Sciences Xi’an 710075 China 7. graduate School of the chinese {2. of sciences Beijing 100039 China 2. Department of Urban and Resources sciences Nanjing University Nanjing 210093 China 3. Department of Earth sciences Nanjing University Nanjing 210093 China 4. Department of Geography Shaanxi Normal University Xi’an 710062 China 5. Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China 6. Department of Geography Qinghai Normal University Xining 810008 China

The Red Earth deposit around Xining, northeastern Tibetan Plateau, has beenstudied in terms of soil micro-structure, grain-size distribution, major- and trace-elementchemistry and magne-tostratigraphy. Field investigations indicate that the Red Earth sequenceconsists of 2. visually definable yellow-brown and weakly-developed soils interbedded with reddishstrongly-developed soils, and has a similar structure to the aeolian Red Clay deposit on the chineseLoess Plateau. Grain-size analysis shows that the Red Earth deposit is very fine-grained with anegligible sand fraction ( > 63 μm). Thin-section observations under light microscopy show that thedeposit has a clayey texture and the coarse fraction ( > 10 μm) mainly consists of quartz,feldspar and micas. Pyroxene and hornblende were also observed. This mineralogical composition ofthe coarse fraction is similar to that of the Quaternary loess. In addition, all of the mineralgrains are semi angular semi-angular and are generally finer than 63 μm. There is a good agreementbetween the major and minor trace element chemistry of loess-soil units and the Red Earth *** REE distributions of the loess-soil and the Red Earth deposit are similar in shape, withenriched LREE and fairly flat HREE profiles and a clear negative Eu anomaly. The geochemicalcharacteristics of the Red Earth deposit are also identical to those of upper continental crust,thus indicating a wind-blown origin. Magnetostratigraphic investigation shows that onset of the RedEarth deposition predates 11.4.Ma BP (13.6 Ma at a nearby site). The distribution of the reportedMiocene aeolian loess at Qin''an of the Loess Plateau is still unknown. Our results indicate thatthis aeolian deposit had extended to the northeastern Tibetan Plateau by at least the middleMiocene. The similarity of the element geochemistry between the Red Earth deposit and the overlyingloess shows that they may have similar sources and dynamic transport system, and may indicate thatthe

关键词： Red Earth deposit, Northeastern Tibetan Plateau, aeolian deposit, aridity of Asia, the middle Miocene.

The influence of moderate ENSO on summer rainfall in eastern China and its comparison with strong ENSO

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chinese Science Bulletin 2008年第5期53卷 791-800页

作者： XUE Feng1 & LIU ChangZheng1,2.1 Institute of Atmospheric Physics, chinese academy of {2., {4. 10002., China 2.{4. University of chinese academy of {2., {4. 10004., China chinese Acad Sci Inst Atmospher Phys Beijing 100029 Peoples R China.

The 6 major ENSO events since 1979 are classified into the strong and moderate ENSO based on in-tensity. The composite analysis is performed to reveal the influence of ENSO on East Asian summer monsoon (EASM) and summer rainfall in eastern China. It is shown that the influence is changed with the seasonal cycle in summer, with a weaker influence in June and a stronger influence in August, in-dicating a long lagged effect of ENSO on EASM. Besides, the circulation and rainfall anomalies caused by the strong ENSO are also stronger with an earlier starting time, while the influence of the moderate ENSO is evident in August. The composite summer rainfall in eastern China for the moderate ENSO exhibits a northern rainfall pattern, which is totally different from the classical ENSO-type rainfall pat-tern. Based on the composite analysis, two moderate ENSO years with a similar intensity (i.e., 1995 and 2.03) are compared. The result shows that, the response of EASM to the moderate ENSO during June and July is, to a certain degree, modulated by the circulation systems in mid-high latitudes of Eurasia and in the Southern Hemisphere, thereby inducing a different rainfall distribution in eastern China. In comparison with the strong ENSO in 1983, it is further revealed that, the strong ENSO plays a dominant role in summer rainfall anomalies in eastern China as well as in controlling the influence of the other factors on EASM. The strong ENSO is therefore different with the moderate ENSO.

关键词：中国东部海洋气象学厄尔尼诺现象东亚季风降雨

High-temperature phases of pyrophyllite and their evolutionary characteristics

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chinese Science Bulletin 1997年第2期42卷 140-144页

作者： WANG Ling and ZHANG Zhenyu1. Changsha Institute of Geotectonics, chinese academy of {2., Changsha 4.0013, China 2. Institute of Geology, chinese academy of {2., beijing 10002., China Changsha Institute of Ceotectonics Chinese Academy of Sciences Changsha China Institute of Geology Chinese Academy of Sciences Beijing China

WITH the increase of heating temperature, phase of pyrophyllite will undergo a series of transformations. Former scholars have done some work in this respect; the temperature spans,however, were normally not more than 1150℃ and no relatively comprehensive results have been reported. Thus, the features of the phases from indoor temperature to melting point (1710℃±) for pyrophyllite and the entire evolutionary process of the phases are uncertain.

关键词： pyrophyllite high-temperature phase phase tranformation pyrophyllite anhydrite mullite cristobalite.

On some tests-based projection pursuit for elliptical symmetry of a high-dimensional distribution

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chinese Science Bulletin 1998年第6期43卷 450-458页

作者： JING Ping 1 and ZHU Lixing 2.1. Mathematics Lab, China University of Mining & Technology, beijing 100083, China 2. Probability Lab, Institute of Applied Mathematics, chinese {2. of sciences, beijing 100080, China Mathematics Lab China University of Mining & Technology Beijing China Probability Lab Institute of Applied Mathematics Chinese Academy of Sciences Beijing China

Some test statistics of Kolmogorov type and Cramér-von Mises type based on projection pursuit technique are proposed for the testing problem of sphericity of a high-dimensional distribution. The limiting distributions of the test statistics are derived under the null hypothesis and under any fixed alternative. The asymptotic properties of bootstrap approximation are investigated. Furthermore, for computational reasons, an approximation for the statistics, based on the number theoretic method, is suggested.

关键词： bootstrap approximation projection pursuit type statistic elliptical symmetry.

Persistent anomalous flows over the subtropical western Pacific insummer

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chinese Science Bulletin 1998年第8期43卷 672-675页

作者： ZHUANG Shiyu\+1 and JI Liren\+2.1. National Meteorological Centre, China Meteorological Administration, beijing 100081, China 2. LASG, Institute of Atmospheric Physics, chinese {2. of sciences, beijing 100080, China National Meteorological Ccntre China Meteomlcgical Administration Beijing China LASG Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China

The distribution of global persistent anomalies shows that the subtropical western Pacific is a key region with high_frequency occurrence of persistent anomalies. Analyses of streamfunction anomalies, OLR anomalies etc. suggest that the convective heating related to Indian monsoon might be responsible for the development of WPA. The results of numerical experiment by two linear barotropic models support the observation.

关键词： persistent anomalies subtropical high Indian monsoon anomalous forcing.

Narrow line Seyfert 1 galaxies: where are the broad line regions?

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Science China(Physics,Mechanics & Astronomy) 2010年第12期53卷 2307-2311,2339-2343页

作者： MAO WeiMing 1,2.3 , HU Chen 2., WANG JianMin 2., BIAN WeiHao 4., ZHANG Shu 2.& ZHAO Gang 1 1 Key Laboratory of Optical Astronomy, National Astronomical Observatories, {4. academy of {2., beijing 100012. China 2.Key Laboratory for Particle Astrophysics, Institute of High Energy Physics, {4. academy of {2., beijing 10004., China 3 {14. University of the {4. academy of {2., beijing 10004., China 4.Department of Physics, Nanjing Normal University, Nanjing 2.0011, China 1. Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China2. Key Laboratory for Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China3. Graduate University of the Chinese Academy of Sciences Beijing 100049 China4. Department of Physics Nanjing Normal University Nanjing 210011 China

A sample consisting of 2.1 narrow line Seyfert 1 galaxies (NLS1s) with high quality spectra from the Sloan Digital Sky Survey (SDSS) is selected to explore where broad line regions are in these objects. We find that the Hβ profile can be fitted well by three (narrow, intermediate and broad) Gaussian components, and the FWHM ratios of the broad to the intermediate components hold a constant of 3.0 roughly for the entire sample. If the broad components originate from the region scaled by the well-determined Hβ reverberation mapping relation, we find that the intermediate components originate from the inner edge of the torus, which is scaled by dust K-band reverberation. We find that the IC and the BC are strongly linked dynamically, but the relation of their covering factors is much more relaxed, implying that both regions are clumpy.

关键词： black hole physics galaxies: evolution quasars: general