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Inosine inhibits apoptosis and cytochrome C mRNA expression in rat neurons after cerebral ischemia/reperfusion

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Neural Regeneration research 2006年第7期1卷 589-592页

作者： Jinrong Wang1, Mingjun Bi1, Qin Li2.1Department of Neurology, Rongcheng Second People’s Hospital, Rongcheng 2.4309, shandong province,{2. 2.epartment of Neurology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei province,{2. Department of Neurology Rongcheng Second People's Hospital Rongcheng 264309 Shandong Province China Department of Neurology Union Hospital Huazhong University of Science ad Technology Wuhan 430030 Hubei Province China

BACKGROUND: It has been demonstrated that adenosine can induce glial cell to release cytochrome C, enhance expression of apoptotic gene bax, inhibit anti-apoptotic gene bcl-2. and activate caspase-3 to apoptosis; Whereas inosine can inhibit neuronal apoptosis which is similar to bcl-2. OBJECTIVE: To observe the effects of inosine on neuronal apoptosis and expression of cytochrome C mRNA in rats after focal cerebral ischemia/reperfusion, and analyze the pathway of its neuroprotective effect. DESIGN: A randomised controlled animal trial. SETTINGS: Department of Neurology, Rongcheng Second People's Hospital; Department of Neurology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology. MATERIALS: Sixty-eight rats, weighing 2.0-2.0 g and clean grade, were used. TdT-mediated dUTP-biotin nick end labeling (TUNEL) and cytochrome C mRNA in situ hybridization kits and DAB staining kit were purchased from Wuhan Boster Biological Co., Ltd.; Inosine injection [2.0 mg (2.mL) each] from Qingdao First Pharmaceutical Factory. METHODS: The experiment was accomplished in the animal experimental center in Tongji Medical College of Huazhong University of Science and Technology from December 2.03 to June 2.05. ① Sixty-four rats were made into focal ischemia by middle cerebral artery occlusion (MCAO) with a nylon monofilament suture. The successfully induced rats were assigned to inosine group (n =32. and model group (n =32. at random. Rats in the inosine group were intraperitoneally administrated with inosine in dose of 100 mg/kg preoperatively, twice a day, 7 days in all. The rats in the control group were injected with the same dose of saline solution by the similar way preoperatively. Each group was randomized into ischemia /reperfusion 2. 6, 12. 2. hours, 2. 3, 7 and 14 days subgroups consisted of 4 rats. The other 4 rats were taken as the sham-operated group, the rats were given the same treatment except for not introduced the filament in

关键词： mRNA Inosine inhibits apoptosis and cytochrome C mRNA expression in rat neurons after cerebral ischemia/reperfusion

Three-year changes of surface albedo of degraded grassland and cropland surfaces in a semiarid area

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Chinese Science Bulletin 2008年第8期53卷 1246-1254页

作者： LIU HuiZhi1↑, TU Gang2.3 & DONG WenJie4 1 State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry, Institute of Atmospheric Physics, Chi- nese Academy of Sciences, Beijing 10002., china 2.Laboratory of research for Middle-High Latitude Circulation System and East Asia Monsoon, china Meteorological Administration, Changchun 130062. china 3 Institute of Meteorological Science of Jilin province, Changchun 130062. china 4 National Climate center, Beijing 100081, china State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry Institute of Atmospheric Physics Chinese Academy of Sciences Beijing China Laboratory of research for Middle-High Latitude Circulation System and East Asia Monsoon China Meteorological Administration Changchun China Institute of Meteorological Science of Jilin province Changchun China National Climate center Beijing China

Diurnal, seasonal and interannual variations of surface albedo of degraded grassland and cropland surfaces at a semiarid area of Tognyu have been investigated based on the continuous three years observational data from 2.03 to 2.05. The changes of surface albedo with solar elevation angle and soil moisture have been discussed also. It has been found that surface albedo has almost the same diurnal and seasonal variations on degraded grassland and cropland surfaces in the semiarid area, while sur- face albedo is large in winter and small in summer. The diurnal variation of the surface albedo has re- lationship with the weather condition. The diurnal cycle of the surface albedo likes the "U" shape curve in sunny day, while it is low-high after the rain, and high-low after the snow. The surface albedo has large variation in cloudy day, while it has no any variation in overcast day. The large difference of the surface albedo can be 0.04 in winter between two land surfaces, because the snow has large effects on the surface albedo in winter. The rainfall is an important factor in summer on the surface albedo, while the difference of the surface albedo is 0.01 only between two land surfaces. The differences of the surface albedo can also be 0.04 in autumn due to vegetation growing. The seasonal-average surface albeo from 2.03―2.05 is 0.2., 0.2., 0.2., 0.32.respectively in spring, summer, autumn and winter on the degraded grassland surface,while it is 0.2., 0.2., 0.2., 0.33 respectively in spring, summer, autumn and winter on the cropland surface. The surface albedo becomes smaller with the increase of solar elevation angle. When the solar elevation angle is greater than 40°, the surface albedo changes very little and tends to be a constant. The surface albedo has negative exponent functions with soil moisture in the growing season.

关键词：半干旱地区表面反照率土壤湿度草地退化

Analysis of the Comparison of Twice Regional Large Rainstorms in Northwest Yantai City

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Meteorological and Environmental research 2011年第7期2卷 19-22,26页

作者： LIU Xue-ping1,LUAN Dong-hong1,YU Shan-juan2.1.Yantai Meteorological Bureau in shandong province,Yantai 2.4003,{2. 2.Muping Meteorological Bureau in shandong province,Muping 2.4003,{2.

[Objective] The twice regional rainstorms in northwest Yantai in July in 2.09 and July in 2.10 were expounded.[Method] The twice regional rainstorm in northwest Yantai in July in 2.09 and July in 2.10 were selected for comparison analysis by dint of conventional and non-conventional weather data,from the aspects of circulation background,physics quantity,and radar echo,etc.[Result] The twice large rainstorm process were regional convective strong *** rainstorm fell in the northwest of Yantai and had a strong precipitation center above 2.0 *** twice large rainstorm was affected by subtropical and shear *** rainstorm area was related to the location of 588 dagpm line,westerly trough,and shear *** was regional rainstorm of typical subtropical edge warm and wet airstream,combination of low vortex and shear line of *** precipitation occurred around the center of water vapor flux;K index had pretty good indication effects to the generation of *** rainstorm occurred around the place with high K *** K index of twice large rainstorm was larger than or equal to 34 ℃,and was close to the rainstorm falling area where K index was larger than or equal to 35 ℃.The reflection factor of twice large rainstorms at 0.5° elevation,the largest echo intensity was from 55 to 60 dBz,in strip echo from south to north,through the west peninsula,forming train *** data report product also had important reference basis for the report of regional large rainstorm.[Conclusion] The study provided references and basis for the report of large rainstorm in the future.

关键词： Regional large rainstorm Comparison analysis Northwest Yantai china

The Social-Economic Development Mechanisms of china's Top 100 Counties and the Enlightenments to the Progress of Underdeveloped Regions:A Case Study in shandong {2.

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The Social-Economic Development Mechanisms of China's Top 10...

第三世界生态高峰会

作者： Wu P. Zhang Y.Regional Development research center,{2. University,of Technology,Zibo,{2. 2.5049,china

As the foundation and main ingredients of national economy,county economy plays an important role in the regional development, especially in the social-economic development of underdeveloped *** National Bureau of Statistics of{2.(NBSC)announces the Top 100 Counties annually based on the evaluation of all counties’ social-economic development indicators including economic capacity and *** is of great significance to analyze the social-economic development status quo and characteristics,and to discuss the social-economic development mechanisms and achievements of the Top 100 Counties in order to supply examples for the progress of underdeveloped *** is a comparatively developed province in{2.,where the county economy makes great contribution to its social-economic development.2. out of{2.’s Top 100 Connties are within shandong province as NBSC reported in 2.06, which symbolizes its success of county economy *** shandong province as a case study area,this {12. discusses the mechanisms and driving forces of the rapid social-economic development of the Top 100 Counties based on the detailed analysis of current and historical social-economic statistics and survey data,brings forward some practical strategies and suggestions for the underdeveloped regions to achieving a rapid growth of regional development and *** and Suggestions to the underdeveloped regions are including:(1)taking the long view to plan for sustainable development and rural-urban harmonization;(2. speeding up rural urbanization and rural industrialization;(3)adjusting local industry structure and encouraging intensive processing of agriculture products to increase the production value;(4) fostering and improving the local characteristic industries based upon the local comparative advantages;(5)encouraging external investment and the private economy to increase the county economy vigor and promote international trade;(6)co

关键词： The Social-Economic Development Mechanisms of china's Top 100 Counties and the Enlightenments to the Progress of Underdeveloped Regions:A Case Study in shandong {2.

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学校互操作框架(SIF)的多区域通信研究

计算机工程与应用 2005年第30期41卷 130-133页

作者：赵志刚刘方爱山东省计算中心重点实验室济南250007 山东师范大学计算机系济南250014

随着教育信息化导致的数据共享与交换问题的日益突出,教育信息管理方面急需一整套完善的标准。SIF是美国已开始投入使用的教育信息管理标准。对SIF的研究,对我国教育管理信息系统的标准化研究将具有重要意义。该文针对SIF里面的多区域... 详细信息

随着教育信息化导致的数据共享与交换问题的日益突出,教育信息管理方面急需一整套完善的标准。SIF是美国已开始投入使用的教育信息管理标准。对SIF的研究,对我国教育管理信息系统的标准化研究将具有重要意义。该文针对SIF里面的多区域通信问题,在研究了已有的两种SIF多区域通信模型的基础上,提出了一种更加有效的多区域通信模型。并且对新的多区域通信模型,给出了基于W eb服务的实现方法。

关键词：学校互操作框架多区域通信 Web服务 UDDI .Net

Application of Signal Processing Methods to Shear-Wave Splitting Study

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Earthquake research in china 1996年第4期10卷 88-96页

作者： Liu Xiqiang and Zheng ZhizhenSeismological Bureau of shandong province,SSB,Ji’nan 2.0014,{2. center for Seismic Data and Information,SSB,Beijing 100045,{2.

This paper briefly discusses the new methods that the authors have put forward to distinguish splitting *** combining these new methods with other methods,the authors have processed the recorded data of an *** study r... 详细信息

关键词： Shear splitting New methods

Influence of Multifunction Biocontrol Agents on Vegetables Meloidogyne Incognita

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Influence of Multifunction Biocontrol Agents on Vegetables M...

中国植物病理学会2.04年学术年会

作者： YANG Hetong~1, LI Jishun~1, CHEN Kai~1, D.Bazhanova, Kang Qinhai~3(~1 Biology research Institute of shandong Academy of Science, {2., 2.0014, china ~2.Institute of Genetics and Cytology of the National Academy of Science of Belarus, Minsk, 2.0072. Belarus ~3 The center of Agricultural Mechamicals, Dingtao County shandong province, Jining, 2.4111, china)

＜正＞*** YKT41 is obtained through technology of celluler fusion, its parental strains are *** YKT41 and pseudo- monas sp.2.. Pseudomonas sp.418 is separated from agricultural soil. There are activity for Meloidogyne incognita. This paper reported biocontrol activity of two strains on vegetables Meloidogyne incognita. 1 Materials and methods 1.1 Strains and nematodes A. chrooococcum YKT41;Pseudomonas sp. 418;Meloidogyne incognita larvae age 2

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Manufacturing Execution System-Based Real-Time Simulation A Case in the Tire Industry

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Manufacturing Execution System-Based Real-Time Simulation A ...

2.10 International Conference on Management Science (ICMS 2.10)

作者： Weiwei Ning1 2.Diancai Yang 1 Sigang Wang 1 Guilian Zhang 1 1 MESNAC National Tire Process and Control Engineering research center Qingdao {2. 2.School of Control Science and Engineering shandong University jinan {2.

Simulation is an important technology for the management of the manufacturing enterprise,and building a real-time simulation system will make the contribution for the monitoring of the process of production and materials logistics. In this paper a real-time simulation framework based on Manufacturing Execution System（MES） was *** then,we use an application in the tire industry to describe it in detail.

关键词： real-time simulation system integration tire industry manufacturing exrcution system

GIS支持下的鲁东南丘陵区茶树土地适宜性评价

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山地学报 2008年第5期26卷 560-564页

作者：史同广郑昭佩王智勇王林林山东建筑大学遥感与GIS研究中心山东师范大学人口资源环境学院

首先研究了暖温带茶树品种生长与自然条件的关系,分析确定了典型区日照市茶树种植的评价因子;然后在1∶5万比例尺地图上,运用ARCGIS对一月平均风速和不同高度下温度因子进行了模拟,并在模拟了天文辐射的基础上对气温因子进行精细订正;... 详细信息

首先研究了暖温带茶树品种生长与自然条件的关系,分析确定了典型区日照市茶树种植的评价因子;然后在1∶5万比例尺地图上,运用ARCGIS对一月平均风速和不同高度下温度因子进行了模拟,并在模拟了天文辐射的基础上对气温因子进行精细订正;同时结合土壤、坡度、相对湿度等因子建立了评价因子量化分级表;最后,运用了模糊数学(Fuzzy)综合评价模型,实现了土地适宜性评价。按照评价结果将研究区分为茶树最适宜、适宜、次适宜和不适宜种植区,并对各类区进一步作了分析和讨论。

关键词：土地适宜性评价茶树 GIS DEM 鲁东南