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The hidden risk of microplastic-associated pathogens in aquatic environments

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Eco-Environment & Health 2023年第3期2卷 142-151页

作者： Huan Zhong Mengjie Wu Christian Sonne Su Shiung Lam Raymond W.M.Kwong Yuelu Jiang Xiaoli Zhao Xuemei sun Xuxiang Zhang Chengjun Li Yuanyuan Li Guangbo Qu Feng Jiang Huahong Shi Rong Ji Hongqiang Ren School of Environment Nanjing UniversityState Key Laboratory of Pollution Control and Resource ReuseNanjing 210023China Department of Bioscience Arctic Research CentreAarhus UniversityRoskildeDenmark Higher Institution Centre of Excellence(HICoE) Institute of Tropical Aquaculture and Fisheries(AKUATROP)Universiti Malaysia Terengganu21030 Kuala NerusTerengganuMalaysia Department of Biology York University4700 Keele StreetTorontoON M3J 1P3Canada Tsinghua Shenzhen International Graduate School Shenzhen 518055China State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Yellow Sea Fisheries research Institute Chinese Academy of Fishery SciencesQingdao 266071China Institute of Environmental research at Greater Bay Area Key Laboratory for Water Quality and Conservation of the Pearl River DeltaMinistry of EducationGuangzhou UniversityGuangzhou 510006China Key Laboratory of Environment and Health(HUST) Ministry of Education&Ministry of Environmental Protectionand State Key Laboratory of Environmental Health(Incubation)School of Public HealthTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China School of Environmental science and Engineering Guangdong Provincial Key Lab of Environmental Pollution Control and Remediation TechnologySun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Estuarine and coastal research East China Normal UniversityShanghai 200241China University Centre for research and Development Department of ChemistryChandigarh UniversityGharuanMohaliPunjabIndia

Increasing studies of plastisphere have raised public concern about microplastics(MPs)as vectors for pathogens,especially in aquatic ***,the extent to which pathogens affect human health through MPs remains unclear,as controversies persist regarding the distinct pathogen colonization on MPs as well as the transmission routes and infection probability of MP-associated pathogens from water to *** this review,we critically discuss whether and how pathogens approach humans via MPs,shedding light on the potential health risks *** on cutting-edge multidisciplinary research,we show that some MPs may facilitate the growth and long-range transmission of specific pathogens in aquatic environments,ultimately increasing the risk of infection in *** identify MP-and pathogen-rich settings,such as wastewater treatment plants,aquaculture farms,and swimming pools,as possible sites for human exposure to MP-associated *** review emphasizes the need for further research and targeted interventions to better understand and mitigate the potential health risks associated with MP-mediated pathogen transmission.

关键词： Microplastics Pathogens Colonization Transmission Public health

一个新颖南极微生物酯酶EST112.2.功能鉴定和在手性叔醇(S)-芳樟醇制备中的应用（英文）

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有机化学 2018年第5期38卷 1185-1192页

作者：邓盾张云孙爱君赛克胡云峰中国科学院南海海洋研究所中国科学院热带海洋生物资源与生态重点实验室广州510301 中国科学院南海海洋研究所广东省海洋药物重点实验室广州510301 广东省农业科学院动物科学研究所广州510301 中山大学附属肿瘤医院神经外科/神经肿瘤科广州510060 肿瘤医学协同创新中心广州510060 华南肿瘤学国家重点实验室广州510060

手性叔醇是合成药物和一些香料产品的非常重要中间体.芳樟醇是叔醇的一种,不同构型的芳樟醇具有不同的香气.因此如何研发合适的制备方法以获得高光学纯度的芳樟醇等叔醇是急需解决的技术问题.生物酶催化合成符合绿色化学的理念,但是由... 详细信息

手性叔醇是合成药物和一些香料产品的非常重要中间体.芳樟醇是叔醇的一种,不同构型的芳樟醇具有不同的香气.因此如何研发合适的制备方法以获得高光学纯度的芳樟醇等叔醇是急需解决的技术问题.生物酶催化合成符合绿色化学的理念,但是由于叔醇化学结构中的空间位阻影响,使用生物酶催化的拆分反应制备高光学纯度的叔醇比较困难.对来自南极微生物的一个新的酯酶EST112.2.行了功能鉴定,并将其作为合成手性芳樟醇的生物催化剂.EST112.2.以通过不对称水解乙酸芳樟酯获得(S)-芳樟醇.对反应的p H、温度、共溶剂、底物浓度、催化剂用量以及反应时间等参数进行优化,EST112.2.备的(S)-芳樟醇的光学纯度大于66%,得率超过72..EST112.2.备的(S)-芳樟醇的光学纯度要远远高于以往报道.

关键词：生物催化南极微生物酯酶动力学拆分手性叔醇 (S)-芳樟醇

Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19

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Acta Pharmaceutica Sinica B 2020年第7期10卷 1205-1215页

作者： Xiaoyan Liu Zhe Li Shuai Liu Jing sun Zhanghua Chen Min Jiang Qingling Zhang Yinghua Wei Xin Wang Yi-You Huang Yinyi Shi Yanhui Xu Huifang Xian Fan Bai Changxing Ou Bei Xiong Andrew M.Lew Jun Cui Rongli Fang Hui Huang Jincun Zhao Xuechuan Hong Yuxia Zhang Fuling Zhou Hai-Bin Luo Department of Hematology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Guangdong Provincial Key Laboratory of New Drug Design and Evaluation School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhou 510006China Dawu County People’s Hospital Xiaogan 432826China State Key Laboratory of Respiratory Diseases National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120China guangzhou Institute of Pediatrics Guangzhou Women and Children’s Medical CenterState Key Laboratory of Respiratory DiseasesGuangzhou Medical UniversityGuangzhou 510623China Biomedical Pioneering Innovation center(BIOPIC) School of Life SciencesPeking UniversityBeijing 100871China Department of Infectious Disease and Department of Pediatrics The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China center for Innovative Marine Drug Screening&Evaluation(QNLM) School of Medicine and PharmacyOcean University of ChinaQingdao 266100China Walter and Eliza Hall Institute of Medical research and Department of Microbiology&Immunology University of MelbourneParkvilleVic 3052Australia School of Life sciences Sun Yat-sen UniversityGuangzhou 510006China Cardiovascular Department The Eighth Affiliated HospitalSun Yat-sen UniversityShenzhen 518000China State Key Laboratory of Virology College of ScienceInnovation Center for Traditional Tibetan Medicine Modernization and Quality ControlMedical CollegeTibet UniversityLhasa 850000China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(MOE) Hubei Province Engineering and Technology Research Center for Fluorinated PharmaceuticalsWuhan University School of Pharmaceutical SciencesWuhan 430071China

Severe acute respiratory syndrome coronavirus 2.SARS-CoV-2.infection can cause acute respiratory distress syndrome,hypercoagulability,hypertension,and multiorgan *** antivirals with safe clinical profile are urgently needed to improve the overall *** an analysis of a randomly collected cohort of 12. patients with COVID-19,we found that hypercoagulability as indicated by elevated concentrations of D-dimers was associated with disease *** virtual screening of a *** approved drug library,we identified an anticoagulation agent dipyridamole(DIP)in silico,which suppressed SARS-CoV-2.replication in *** a proof-of-concept trial involving 3. patients with COVID-19,DIP supplementation was associated with significantly decreased concentrations of D-dimers(P2.5%)was in clinical remission.

关键词： Dipyridamole SARS-CoV-2 COVID-19 Treatment D-dimer Severe cases

基于δ+-SPH模型的三维鱼自主游动问题研究

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Acta Mechanica Sinica 2023年第1期39卷 168-178页

作者：黄晓婷孙鹏楠吕鸿冠钟诗蕴 School of ocean Engineering and technology Sun Yat-sen University Zhuhai 519082 China Southern Marine science and Engineering Guangdong Laboratory (Zhuhai) Zhuhai 519080 China

仿生推进研究对水下潜器的水动力性能和续航能力提升具有重要意义.为此,本文采用光滑粒子流体动力学(Smoothed Particle Hydrodynamics,SPH)方法研究了三维鱼自主游动的流固耦合(fluid-structure interaction,FSI)问题.为提高SPH模型的... 详细信息

仿生推进研究对水下潜器的水动力性能和续航能力提升具有重要意义.为此,本文采用光滑粒子流体动力学(Smoothed Particle Hydrodynamics,SPH)方法研究了三维鱼自主游动的流固耦合(fluid-structure interaction,FSI)问题.为提高SPH模型的计算精度和效率,文中采用了δ+-SPH模型并结合了张力不稳定控制技术(tensile instability control,TIC)和自适应粒子细化(adaptive particle refinement,APR)算法等.计算结果部分,为了验证SPH结果的精度和稳定性,首先采用三维球体绕流基准算例进行验证,随后将三维鱼游动速度与文献结果进行对比.通过比较二维和三维鱼自主推进的结果发现,两者预报的游动速度和涡量场均存在较大差异,凸显了三维研究的必要性.此外,本文对三维鱼尾流的涡结构进行了可视化,并展开详细讨论.结果表明,本文所建立的三维δ+-SPH模型为研究真实鱼类的仿生水动力性能提供了一种新的可靠手段.

关键词：光滑粒子流体动力学仿生推进水动力性能续航能力游动速度水下潜器 SPH 自主游动

New Insights into Nanostructure and Geochemistry of Bioapatite in REE-Rich Sediments: LA-ICP-MS,TEM,and Z-Contrast Imaging Studies

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New Insights into Nanostructure and Geochemistry of Bioapati...

中国矿物岩石地球化学学会第17届学术年会

作者： Jianlin Liao Xiaoming sun Dengfeng Li Rina Sa Yang Lu Zhiyong Lin Li Xu Runze Zhan Yuguan Pan Huifang Xu School of Earth sciences and Engineering Sun Yat-sen University School of Marine sciences Sun Yat-sen University Guangdong Provincial Key Laboratory of Marine Resources and coastal Engineering Southern Laboratory of ocean science and Engineering (Guangdong Zhuhai) guangzhou Marine Geological Survey State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen University State Key Laboratory for Mineral Deposits research School of Earth Sciences and EngineeringNanjing University Department of Geoscience University of Wisconsin

Rare earth elements (REE) and yttrium (Y), termed as REY, are recently found to be extremely enriched in some pelagic sediments,which could be an important resource for REY in the future. However, their enrichment mechanism remains controversial (or under debate).Because biogenetic apatite is one of the most important REY carriers in REY-rich deep-sea

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盘点气候风险机遇,展望健康繁荣未来

科学通报 2024年第27期69卷 4005-4011页

作者：张诗卉张弛蔡闻佳白玉琪 Max Callaghan 常楠陈彬陈慧琪程亮亮戴瀚程代鑫范维澄房小怡高仝耿阳关大博胡艺馨华峻翊黄存瑞黄弘黄建斌黄小猛纪思翰蒋俏蕾姜晓朋 Gregor Kiesewetter 李湉湉梁璐林波荣林华亮刘欢刘起勇刘小波刘钊刘竹刘昱甫陆波鲁晨曦罗震宇马伟米志付任超 Marina Romanello 沈鉴翔苏婧孙语泽孙昕璐汤绪 Maria Walawender 王灿王情汪蕊 Laura Warnecke 魏汪宇文三妹谢杨熊辉徐冰颜钰杨秀姚芳虹俞乐袁嘉灿曾仪娉张镜张璐张锐张尚辰张少辉赵梦真郑大山周浩周景博周子乔罗勇宫鹏清华大学地球系统科学系北京100084 北京理工大学管理学院北京100081 Mercator research Institute on Global Commons and Climate Change Mercator Research Institute on Global Commons and Climate ChangeBerlin 10829Germany 南京医科大学公共卫生学院南京211166 北京师范大学环境学院北京100875 中山大学公共卫生学院广州510080 北京大学环境科学与工程学院北京100871 清华大学公共安全研究所北京100084 清华大学工程物理系北京100084 中国气象科学研究院气象影响与风险研究中心北京100086 山东师范大学商学院济南250013 清华大学建筑学院北京100084 南方科技大学统计与数据科学系深圳518055 中国海洋大学国际事务与公共管理学院青岛266003 清华大学万科公共卫生学院北京100084 清华大学新闻与传播学院北京100084 世界卫生组织驻华代表处北京100600 Pollution Management research Group EnergyClimateand Environment ProgramInternational Institute for Applied Systems Analysis(IIASA)Laxenburg 1-A-2361Austria 中国疾病预防控制中心环境与健康相关产品安全所环境健康风险评估室北京102206 Department of Landscape Architecture&Environmental Planning University of CaliforniaBerkeley CA 94607USA 清华大学环境学院北京100084 中国疾病预防控制中心传染病预防控制所传染病预防控制国家重点实验室北京102206 北京经济管理职业学院临空经济管理学院北京100102 中国气象局国家气候中心北京100081 Geography College of Life and Environmental SciencesUniversity of ExeterExeter EX12LUUK 山东大学齐鲁医学院公共卫生学院流行病学系济南250002 The Bartlett School of Sustainable Construction University College LondonLondon WC1H 0ALUK 香港大学建筑学院中国香港999077 Institute for Global Health University College LondonLondon WC1H 0ALUK 清华大学人文学院北京100084 复旦大学大气与海洋系/大气科学研究院上海200438 复旦大学极端天气/气候事件与人体健康风险互联和治理国际卓越中心上海200438 北京航空航天大学经济与管理学院北京100083 香港科技大学计算机科学与工程系广州511453 清华大学气候变化与可持续发展研究院北京100084 北京大学体育教研部北京100871 清华大学苏世民学院北京100084 清华大学城市治理与可持续发展研究院北京100084 百度研究院北京100091 香港大学地球科学系和地理系中国香港999077

气候变化带来的健康风险与日俱增,煤炭消费及相关碳排放量的反弹,再度敲响了中国气候变化警钟.2.2.年,中国面临了严峻的气候挑战.极端天气事件发生的频率和强度不断上升,许多地区气温纪录屡创新高,全国平均气温攀升至历史第二高位,同时... 详细信息

气候变化带来的健康风险与日俱增,煤炭消费及相关碳排放量的反弹,再度敲响了中国气候变化警钟.2.2.年,中国面临了严峻的气候挑战.极端天气事件发生的频率和强度不断上升,许多地区气温纪录屡创新高,全国平均气温攀升至历史第二高位,同时降水量自2.12.以来创新低,南方地区遭遇夏秋连旱,而湖南和东北地区则出现了极端降雨和洪涝灾害.采取及时、充分的措施不仅能减轻气候变化对健康的影响,还将保护基础设施不被极端天气破坏.

关键词：煤炭消费极端天气事件基础设施气候变化极端降雨碳排放量气候风险盘点

海洋一号C星光学载荷对海面溢油的识别能力分析

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遥感学报 2020年第8期24卷 933-944页

作者：沈亚峰刘建强丁静焦俊男孙绍杰陆应诚南京大学国际地球系统科学研究所南京210046 国家卫星海洋应用中心北京100081 自然资源部空间海洋遥感与应用重点实验室北京100081 中山大学海洋科学学院珠海510275

中国首颗海洋水色业务卫星(HY-1C)搭载有水色水温扫描仪(COCTS)、海岸带成像仪(CZI)、紫外成像仪(UVI)等多套光学载荷,已于2.19-06开展业务化运行。溢油是海洋环境监测的重要目标之一。近年来,光学遥感对海面溢油不同污染类型的识别、... 详细信息

中国首颗海洋水色业务卫星(HY-1C)搭载有水色水温扫描仪(COCTS)、海岸带成像仪(CZI)、紫外成像仪(UVI)等多套光学载荷,已于2.19-06开展业务化运行。溢油是海洋环境监测的重要目标之一。近年来,光学遥感对海面溢油不同污染类型的识别、分类与估算原理得以阐明,其技术优势获得认可,能有效促进海面溢油的精细化定量探测。本研究以中国近海,主要以2.19-02.2.中国南海东沙岛附近海域一次溢油事件为例,收集了HY-1C星COCTS和CZI数据,并获取了同一天的VIIRS、MODIS Terra&Aqua遥感数据,开展了海面溢油的识别分类及其对比分析,重点评估COCTS与CZI光学载荷对海面溢油识别的效能。结果表明:在弱耀光对比条件下,COCTS、CZI、VIIRS均能有效识别此次东沙岛溢油,且COCTS对溢油的识别能力不弱于VIIRS数据;CZI不仅能识别此次溢油,还能区分此次溢油形成的海面油膜与溢油乳化物,从而提供更多的判定信息;CZI数据中,不同溢油污染类型的光谱信号离散度大于清洁海水平均噪声,展现了溢油量估算的潜力。HY-1C星光学载荷展现了优良的辐射分辨率、高信噪比等性能,随着HY-1D星的发射,双星组网观测还能提供更佳的时相分辨率数据,未来会在海洋溢油的实时、定量、精细化观测中提供丰富的数据支撑。

关键词：遥感 HY-1C星水色水温扫描仪海岸带成像仪溢油光学遥感

Possible obliquity-forced warmth in southern Asia during the last glacial stage

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science Bulletin 2021年第11期66卷 1136-1145,M0004页

作者： Cheng Zhao Eelco J.Rohling Zhengyu Liu Xiaoqiang Yang Enlou Zhang Jun Cheng Zhonghui Liu Zhisheng An Xiangdong Yang Xiaoping Feng Xiaoshuang sun Can Zhang Tianlong Yan HaoLong Hong Yan Zicheng Yu Weiguo Liu Shi-Yong Yu Ji Shen State Key Laboratory of Lake science and Environment Nanjing Institute of Geography and LimnologyChinese Academy of SciencesNanjing 210008China center for Excellence in Quaternary science and Global Change Chinese Academy of SciencesXi’an 710061China School of Geography and ocean science Nanjing UniversityNanjing 210023China research School of Earth sciences the Australian National UniversityCanberra ACT 2601Australia ocean and Earth science University of SouthamptonNational Oceanography CentreSouthampton SO143ZHUK Department of Geography Ohio State UniversityColumbus 43210USA Department of Earth sciences Sun Yat-sen UniversityGuangzhou 510275China Laboratory of Meteorological Disaster Ministry of Education(KLME)/Joint International Research Laboratory of Climate and Environment Change(ILCEC)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science and TechnologyNanjing 210044China Department of Earth sciences University of Hong KongHong Kong 999077China State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China Department of Earth and Environmental sciences Lehigh UniversityBethlehem 18015USA Institute for Peat and Mire research School of Geographical SciencesNortheast Normal UniversityChangchun 130024China School of Geography Geomaticsand PlanningJiangsu Normal UniversityXuzhou 221116China

Orbital-scale global climatic changes during the late Quaternary are dominated by high-latitude influenced~100,000-year global ice-age cycles and monsoon influenced~2.,000-year low-latitude hydroclimate ***,the shortage of highly-resolved land temperature records remains a limiting factor for achieving a comprehensive understanding of long-term low-latitude terrestrial climatic ***,we report paired mean annual air temperature(MAAT)and monsoon intensity proxy records over the past 88,000 years from Lake Tengchongqinghai in southwestern *** summer monsoon intensity follows the~2.,000-year precession beat found also in previous studies,we identify previously unrecognized warm periods at 88,000-71,000 and 45,000-2.,000 years ago,with 2.3.amplitudes that are close to our recorded full glacial-interglacial *** advanced transient climate simulations and comparing with forcing factors,we find that these warm periods in our MAAT record probably depends on local annual mean insolation,which is controlled by Earth’s~41,000-year obliquity cycles and is anti-phased to annual mean insolation at high *** coincidence of our identified warm periods and intervals of high-frequent dated archaeological evidence highlights the importance of temperature on anatomically modern humans in Asia during the last glacial stage.

关键词： Southern Asia Lake sediments brGDGTs Annual temperature The last glacial stage Obliquity forcing

基于Google Earth Engine的1986—2.18年广东红树林年际变化遥感分析

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热带地理 2020年第5期40卷 881-892页

作者：王子予刘凯彭力恒曹晶晶孙映雪钱雨昕史舒悦中山大学地理科学与规划学院//广东省公共安全与灾害工程技术研究中心//广东省城市化与地理环境空间模拟重点实验室广州510275 南方海洋科学与工程广东省实验室(珠海) 广东珠海519000

以广东沿海红树林为研究对象,结合谷歌地球引擎(GEE)云计算平台,以1986—2.18年3.0}3.59景Landsat系列卫星遥感影像为数据源,采用随机森林(RF)方法提取1986—2.18年广东省红树林面积,比较全省沿海城市红树林年际时空变化特征,并从景观... 详细信息

以广东沿海红树林为研究对象,结合谷歌地球引擎(GEE)云计算平台,以1986—2.18年3.0}3.59景Landsat系列卫星遥感影像为数据源,采用随机森林(RF)方法提取1986—2.18年广东省红树林面积,比较全省沿海城市红树林年际时空变化特征,并从景观斑块角度分析广东省红树林斑块演变特征。结果表明:1)1986—2.18年红树林遥感分类总体精度均高于90%,广东省沿岸红树林面积总体呈先减少后增加的趋势,且其在2.14年后变化幅度逐渐减小。2.从各沿海城市来看,红树林共分布在14个市内,其中湛江和阳江是红树林面积分布最大的2.城市;各市红树林面积变化可分为先减后增、波动增加和无明显变化3.。3.1986—2.18年广东省红树林斑块数量总体呈减少趋势,但斑块平均面积(MPS)呈上升趋势,红树林破碎化程度减轻。获取年际红树林面积分布信息和空间结构变化趋势,可为红树林合理开发与保护提供数据和参考,服务于红树林生态恢复和精细化管理。

关键词：红树林年际变化监测 Google Earth Engine 随机森林广东省