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china Communications 2012年第7期9卷 121-126页

作者： Sun Haixin Guo Yuhui Kuai Xiaoyan Cheng En key laboratory of Underwater Acoustic Communication and Marine Information Technology({2. university) Ministry of EducationXiamen 361005P.R.China

Abstract： In order to gain a better performance and reduce the computational complexity of the filter design in the underwater acoustic single car rier system, a new Iterative Block DFE （IBDFE） is proposed, which operates iteratively on blocks of the received signal, and fully implements its filtering operations by Discrete Fourier Trans forms （DFTs）. Two design methods are consid ered for IBDFE： one is HDIBDFE, and the oth er is SDIBDFE. In this paper, the first one is a dopted. In this scheme,

关键词： underwater acoustic system single carrier IBDFE

Fluorescent Core-shell Silica Nanoparticles as Functionable Precursors:Towards Multicolor and Multifunctional Nanoprobes

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Fluorescent Core-shell Silica Nanoparticles as Functionable ...

第三十五届国际光谱会议

作者： C.L.Wu J.Q.Hong X.Q.Guo Y.B.Zhao~* Department of Chemistry and the key laboratory of {2. sciences of the ministry of education College of Chemistry and Chemical Engineering xiamen university xiamen 361005 china

＜正＞Rational design of functional nanoparticles has attracted a great deal of attention in multiplex bioanalysis and multifunctional ***,we have proposed a post-encoding concept[1]to the design and preparation of encoding fluorescent probes, which makes the preparation process of multicolor fluorescent spheres rather laborsaving

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冠瘤海鞘幼体附着和变态的离子控制

海洋学报 2005年第1期27卷 137-144页

作者：黄英柯才焕冯丹青周时强李复雪厦门大学海洋系厦门大学厦门大学亚热带海洋研究所福建厦门361005 厦门大学海洋环境科学教育部重点实验室福建厦门361005 究所福建厦门361005

研究了人工海水中三种金属离子K+,Mg2.和Ca2.分别在不同浓度下对冠瘤海鞘(Styelaca nopusSavigny)幼体附着和变态的影响,同时采用K+通道阻滞剂TEA检验其可兴奋细胞膜上的K+通道特性,对冠瘤海鞘幼体附着和变态的离子控制机制进行初步探讨... 详细信息

研究了人工海水中三种金属离子K+,Mg2.和Ca2.分别在不同浓度下对冠瘤海鞘(Styelaca nopusSavigny)幼体附着和变态的影响,同时采用K+通道阻滞剂TEA检验其可兴奋细胞膜上的K+通道特性,对冠瘤海鞘幼体附着和变态的离子控制机制进行初步探讨,结果表明:K+的浓度为2.~40mmol/dm3 时诱导幼体附着和变态的效果最佳,低于4 5mmol/dm3 和高于80mmol/dm3 的K+浓度都表现出抑制效果;Mg2.浓度在0 ~ 32.mmol/dm3 时显著促进幼体附着和变态,达88mmol/dm3时起抑制作用;在人工海水中无论添加或减少Ca2.,均有效抑制幼体变态.TEA不能阻抑增加K+的诱导作用,这表明冠瘤海鞘幼体可兴奋细胞膜上的K+通道对外部TEA不敏感.另外,人工海水中缺乏K+或Ca2.或K+浓度达80mmol/dm3 都会对冠瘤海鞘幼体产生毒害作用.

关键词：冠瘤海鞘幼体附着变态离子控制海鞘

手性流动相添加剂高效液相色谱法分离苯基琥珀酸对映体

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分析测试学报 2004年第1期23卷 55-57页

作者：阮源萍郑子达张雪曼黄培强厦门大学化学系

以七 (2.3,6_三_O_甲基 )_β_环糊精 (TM_β_CD)作为手性流动相添加剂 ,反相高效液相色谱研究苯基琥珀酸 (PSA)对映体拆分 ;在Nova-pakC18 色谱柱上 ,采用0.30mmol/LTM_β_CD、含0.05 %三氟乙酸的乙腈 -水(体积比16∶84)为流动相 ,(R)_(... 详细信息

以七 (2.3,6_三_O_甲基 )_β_环糊精 (TM_β_CD)作为手性流动相添加剂 ,反相高效液相色谱研究苯基琥珀酸 (PSA)对映体拆分 ;在Nova-pakC18 色谱柱上 ,采用0.30mmol/LTM_β_CD、含0.05 %三氟乙酸的乙腈 -水(体积比16∶84)为流动相 ,(R)_( -)_PSA和(S)_( +)_PSA的容量因子分别为5.43和6.42.,对映体分离因子为1.18 ,分离度为2.50 ;对比PSA在 β_CD手性流动相法和2.6_丁基化_β_CD涂渍C18柱的色谱行为 ,探讨环糊精分子对PSA的手性拆分机理 ;本法已用于测定L_脯氨酸化学拆分苯基琥珀酸对映体产品的光学纯度。

关键词：苯基琥珀酸对映体分离手性流动相添加剂高效液相色谱法七(2.3,6三-O-甲基)-β-环糊精

Stability of axially restrained steel columns under temperature action

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science china(Technological sciences) 2010年第12期53卷 3349-3355页

作者： CAI JianGuo1, FENG Jian1, ZHAO YaoZong1 & XU YiXiang2.1 key laboratory of C & PC Structures of {2. of education, Southeast university, Nanjing 2.0096, china 2.Department of Civil Engineering, Strathclyde university, Glasgow G12.8QQ, United Kingdom 1. key laboratory of C & PC Structures of {2. of education Southeast University Nanjing 210096 China2. Department of Civil Engineering Strathclyde University Glasgow G12 8QQ UK

The in-plane elastic buckling of a steel column under thermal loading is investigated. The column is pinned at its ends, with two linear elastic springs that model the restraint provided by adjacent members in a structural assemblage or an elastic foundation. Across a section, the temperature is assumed to be linearly distributed. Based on a nonlinear strain-displacement relationship, the energy method is used to obtain the equilibrium and buckling equations. Then the buckling of columns with three different thermal loading cases is studied. The results show that the analytical formulas can be used to evaluate the critical temperature for elastic buckling. The thermal gradient plays a positive role in improving the stability of columns. Comparing these predictions with uniform temperature distribution over cross section, it can be shown that the buckling load is seriously underestimated. It can also be found that axial restraints can significantly affect the column elastic buckling loads. The critical temperature decreases with an increase of restraint stiffness. Furthermore, the effect of axial stiffness increases when increasing the thermal gradients and decreasing the slenderness ratio of columns.

关键词： buckling steel column thermal restraint analytical analysis elasticity

Ansamycin antibiotics induce ROS generation and Cell Cycle Arrest in MDA-MB-435 Cells

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Ansamycin antibiotics induce ROS generation and Cell Cycle A...

Degradation of retinoid X receptor α by TPA through proteasome pathway in gastric cancer cells

2.08年中国病理生理学会第十一届肿瘤和第十二届免疫专业委员会学术会议

作者： Baobing Zhao Yuemao Shen key laboratory of the {2. of education for Cell Biology and Tumor Cell Engineering xiamen Engineering Research Center of Marine Microbial Drug Discovery Fujian Engineering laboratory for Pharmaceuticals School of Life science,xiamen university,xiamen,Fujian 361005,P.R.china

Ansamycins are a family of polyketide macrolactams,exemplified by the anti-tubercular agent rifamycin and the antitumor agent *** molecular architecture is characterized by an aromatic chromophore with an aliphatic ch...

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World Journal of Gastroenterology 2003年第9期9卷 1915-1919页

作者： Xiao-Feng Ye Su Liu Qiao Wu Xiao-Feng Lin Bing Zhang Jia-Fa Wu Ming-Qing Zhang Wen-Jin Su key laboratory of the {2. of education for Cell Biology and Tumor Cell Engineering,School of Life sciences,xiamen university,xiamen 361005,Fujian Province,china Xiao-Feng Ye Su Liu Qiao Wu Xiao-Feng Lin Bing Zhang Jia-Fa Wu Ming-Qing Zhang Wen-Jin Su Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering School of Life Sciences Xiamen University Xiamen 361005 Fujian Province China

AIM: To investigate and determine the mechanism and signal pathway of tetradecanoylphorbol-1, 3-acetate (TPA) in degradation of RXRα.METHODS: Gastric cancer cell line, BGC-82. was used in the experiments. The expression level of R XRα protein was detected by Western blot. Nuclear and cytoplasmic protein fractions were prepared through lysis of cell and *** and translocation of RXRα were observed under laser-scanning confocal microscope through labeling specific anti-RXRα antibody and corresponding immunofiuorescent antibody as secondary antibody. Different inhibitors were used as ***: In BGC-82. cells, RXRα was expressed in the nucleus. When cells were treated with TPA, expression of RXRα was repressed in a time-dependent and TPAconcentration-dependent manner. Meanwhile, translocation of RXR from the nucleus to the cytoplasm occurred, also in a time-dependent manner. When cells were pre-incubated with proteasome inhibitor MG132.for 3 hrs, followed by TPA for another 12.hrs, TPA-induced RXRα degradation was inhibited. Further observation of RXRα translocation in the presence of MG132.showed that MG-132.could block TPAinduced RXRα redistribution. Conversely, when RXRαtranslocation was inhibited by LMB, an inhibitor for blocking protein export from the nucleus, TPA could not repress expression of RXRα.CONCLUSION: TPA could induce the degradation of RXRα protein in BGC-82. cells, and this degradation is time-and TPA-concentration-dependent. Furthermore, the degradation of RXRα by TPA is via a proteasome pathway and associated with RXRα translocation from the nucleus to the cytoplasm.

关键词：胃癌类维生素A受体X TPA BGC-82.细胞

A NEW IMPLICIT SCHEME FOR SOLVING 3-D SHALLOW WATER FLOWS

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Journal of Hydrodynamics 2009年第6期21卷 790-798页

作者： ZHANG Zhuo SONG Zhi-yao LV Guo-nian State key laboratory of Hydrology Water Resources and Hydraulic Engineering Ocean College Hohai University Nanjing 210098 China key laboratory of Virtual Geographic Environment Ministry of Education Nanjing Normal University Nanjing 210097 China

Based on the improved ADI method, this article proposes an improved implicit finite difference scheme for solving 3-D shallow water flows. The main objective is to design a numerical relation between the horizontal velocity on each layer and the depth-averaged velocity for employing the improved ADI method. With the free surface elevation and the depth-averaged velocity obtained by using essentially 2.D depth-averaged mode, the velocity profiles can be obtained easily and simultaneously. The wind-induced flows, the open channel flows due to the pressure gradient and the tidal flows in coastal waters are simulated, and the results are consistent well with the analytical solution and the field data, which shows that the present implicit scheme is stable and effective, and the established model is practical. Moreover, when only one vertical layer is specified, the present 3-D numerical model is reducea to the 2.D depth-averaged model.

关键词： shallow water equation ADI method wind-induced flow gravity-drived flow tidal flow

WAVE MOTION OVER TWO SUBMERGED LAYERS OF HORIZONTAL THICK PLATES

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Journal of Hydrodynamics 2009年第4期21卷 453-462页

作者： LIU Yong LI Yu-cheng TENG Bin key laboratory of Ocean Engineering Shandong Province Ocean University of China Qingdao 266100 China key laboratory of Water and Sediment {2. and Water Hazard Prevention Hunan Province Changsha 410076 China State key laboratory of Coastal and Offshore Engineering Dalian University of Technology Dalian 116024 China

This study investigates the hydrodynamic performance of a submerged two layer horizontal plate breakwater. The plate thickness is considered as non-zero in the study. In the context of linear potential theory, an analytical solution for interaction of water waves with the plates is obtained using the matched eigenfunction expansion method. The solution consists of a symmetric part and an antisymmetric part. Its validity is confirmed by comparing the numerical results of reflection and transmission coefficients for limiting cases with previous predictions. Numerical examples are given to examine the major factors that affect the reflection and transmission coefficients of the plates. Some useful results are presented for engineering design.

关键词： submerged breakwater horizontal thick plate reflection coefficient transmission coefficient