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Biomedical and Environmental sciences 1989年第1期2卷 65-71页

作者： HU WEN-JUAN, CHEN XIAO-MING,~1 MENG HONG-DE,~2.AND MENG ZHAO-HE institute of Nutrition and Food Hygiene, chinese {2. of Preventive Medicine Beijing, china

Flavotoxin A was isolated from Pseudomonas cocovenenans subsp. farinofermentans culture in semisolid potato-dextrose-agar medium, which was isolated from fermented corn meal that had caused food poisoning outbreaks in china. The isolation, purification, and chemical structure of this toxin were studied. The NMR spectra, the uv spectra, and molar extinction coefficients, and the mass spectra of Flavotoxin A are in good agreement with those reported for bongkrekic acid. Therefore, Flavotoxin A and bongkrekic acid are the same organic chemical compound; the molecular formula is C_(2.)H_(38)O_7. The oral LD_(50) of the purified Flavotoxin A in mice was 3.16mg/kg (1.53-6.15mg/kg). The existence of bongkrekic acid in toxic fermented corn samples collected during food poisoning outbreaks was also confirmed. It is concluded that bongkrekic acid has played an important role in the outbreaks of fermented corn poisoning. 1989 Academic Press, Inc.

关键词： Fermented Corn Flour Poisoning in Rural Areas of china Isolation and Identification of Main Toxin Produced by Causal Microorganisms

Analysis of a microcrack model and constitutive equations for time-dependent dilatancy of rocks

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Analysis of a microcrack model and constitutive equations fo...

Optimization　of　harmonious　development　on　regional　energy－economy－atmospheric　environment　system

中国科学院地质与地球物理研究所2.03学术年会

作者： Zuan Chen institute of Geology and Geophysics,chinese {2. of sciences,Beijing 10002.,china

Based on experimental observations and theoretical analyses,the author introduces an ideal microcrack model in which an array of cracks with the same shape and initial size is distributed evenly in *** mechanism of creep dilatancy for rocks is analysed ***, propagation and linkage of pre-existing microcracks during creep are well ***,the relationship between the velocity of microcrack growth and the duration of the creep process is derived *** relationship agrees well with the character of typical experimental creep curves,and includes three stages of *** the damage constitutive equations and damage evolution equations,which describe the dilatant behaviour of rocks,are presented. Because the dilatant estimated value is taken as the damage variable,the relationship between the microscopic model and the macroscopic constitutive equations is *** this way the mechanical behaviour of rocks can be predicted.

关键词： constitutive equation crack growth creep dilatancy microcrack

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Journal of Environmental sciences 1996年第4期8卷 390-396页

作者： Ning Datong,Wang Lei(chinese Real Estate Appraisal and Consulting Center,State Land Administration, Beiging,china.)({2. of Environmental sciences,Beijing Normal University,Beijing 100875,china) institute of Environmental sciences Beijing Normal University Beijing 100875 China chinese Real Est. Appraisal/C.C. State Land Administration Beiging China

The energy,industrial economy and atmospheric environment were taken into account as a whole cornplex system in this study. Based on the application of grey system theory and the analysis of development coefficients about major parameters of the system,the method of grey developrnent decision was approached, and a new concept-integrated development coefficient was put forward. Furthermore,the reasonable ranking of development decision within eight industrial sectors(building materials,coking,food and drink,chemical engineering,paper rnaking,machinery and electrical appliance,textile, mining)has been concluded from the viewpoint of economic growth, energy saving and ambient air quality protection.

关键词： economy atmospheric environment grey development decision.

Speciation and Phylogeography of Opsariichthys bidens （Tdeostei:Cypriniformes） in china:A Study using analysis of the Cytochrome b gene of mtDNA from diverse populations

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Speciation and Phylogeography of Opsariichthys bidens （Tdeo...

PRELIMINARY STUDIES ON THE KINETIC RESOLUTION OF METHYL ERYTHRO-PHENYLGLYCERATE AND METHYL t-EPOXYCINNAMATE BY PLE

中国海洋湖沼学会第九次全国会员代表大会暨学术研讨会

作者： Gaoyan Li Xuzhen Wang Yahui Zhao Jie Zhang Shunping He Chunguang Zhang(1.institute of Zoology,chinese {2. of sciences,Beijing 100101,china 2.Graduate University of chinese academy of sciences,Beijing 100049,china 3.institute of Hydrobiology,chinese {2. of sciences,Wuhan 430072.china)

＜正＞The cyprinid fish Opsariichthys bidens Gunther is distributed endemically in all major river systems of East *** investigate the phylogeographic and demographic history of this species, using the partial sequences of the Cyt b gene in *** samples were collected from almost all major fiver systems where *** is distributed in ***,Candidia and

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chinese Chemical Letters 1992年第2期3卷 95-96页

作者： Jin Fa DU, Jin ZHOU and Liang HUANG~* institute of Materia Medica, chinese {2. of Medical sciences Beijing, 100050

PLE(pig liver esterase) catalyzed hydrolysis of the title compounds demonstrated that the α-carbon with S configuration hydrolyzed faster than the R configuration and α-carbon controlled the stereoselectivity. The p... 详细信息

关键词： PRELIMINARY STUDIES ON THE KINETIC RESOLUTION OF METHYL ERYTHRO-PHENYLGLYCERATE AND METHYL t-EPOXYCINNAMATE BY PLE ZR

四环素-绿色荧光蛋白融合蛋白的构建及其活性测定

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生物工程学报 2005年第1期21卷 97-101页

作者：左妍杨克迁中国科学院微生物研究所微生物资源国家重点实验室

将来源于水母的绿色荧光蛋白基因 (gfp)和来源于E .coli转座子Tn10的四环素阻遏蛋白基因 (tetR)共同构建到E .coli表达载体pET_30a +上 ,获得TetRC_端与GFPN_端融合蛋白。对经诱导表达并纯化后的融合蛋白 (TR∷GFP)进行荧光发射光谱分... 详细信息

将来源于水母的绿色荧光蛋白基因 (gfp)和来源于E .coli转座子Tn10的四环素阻遏蛋白基因 (tetR)共同构建到E .coli表达载体pET_30a +上 ,获得TetRC_端与GFPN_端融合蛋白。对经诱导表达并纯化后的融合蛋白 (TR∷GFP)进行荧光发射光谱分析表明 ,该融合蛋白保留了GFP的荧光特性 ,即在 395nm激发下 ,可在 5 10nm附近有特征发射峰。在加入四环素后 ,融合蛋白在 395nm激发下 ,在 4 0 0nm～ 70 0nm范围内的发射光谱发生明显变化 ,荧光强度普遍增加 ,且以 5 10nm处最大发射峰增幅最大 ,由原来 1 132.至 2. 2.14 ,而四环素对相同浓度的GFP与TetR荧光影响不大 ,结果表明该融合蛋白 ,能感受外界四环素 ,并产生一定的荧光变化。

关键词：绿色荧光蛋白(GFP) 四环素阻遏蛋白(TetR) 荧光光谱荧光强度融合蛋白四环素生物传感器

Genesis of continental seismogenic zone and a new fault zone model

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chinese Science Bulletin 2000年第20期45卷 1886-1892页

作者： LIU Junlai & M. Shimada1. Department of Earth sciences, Changchun University of Science and Technology, Changchun 13002., china 2. RCEP, Disaster Prevention Research {2., Kyoto University, Uji, Kyoto, 611-0011, Japan Correspondence should be addressed to Liu Junlai i Department of Earth sciences Changchun University of Science and Technology Changchun China RCEP Disaster Prevention Research Institute Kyoto University Uji Kyoto Japan

Experiments were conducted repeatedly on Mannari granite under different temperature and confining pressure conditions. Systematic micro- and submicro-structural and mechanical analyses of granite samples deformed under 1.5 GPa (confining pressure), at 2. ℃-650 ℃ temperatures and at 2.10-6s-1 strain rate show the brittle-ductile deformation microstructures and microstructural associations similar to those observed in naturally deformed crustal rocks and minerals. Brittle fracturing and crystalline plasticity co-exist and react with each other in the brittle-ductile transition domain of the continental lithosphere. The interaction between the different mechanisms in the transitional domain results in the variation of anomalous strength values, which may best explain the genesis of the continental seismogenic zone. A new fault zone model is proposed on the basis of detailed micromechanical and microstructural analyses.

关键词： granite experimental rock deformation continental seismogenic zone fault zone model.

ADVANCES STUDY OF china'S ULTRAHIGH-PRESSURE METAMORPHIC ROCKS IN THE PAST 15 YEARS

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Scientia Geologica Sinica 2001年第1期 3-12页

作者： Wang Qingchen Laboratory of Lithosphere Tectonic Evolution, institute of Geology and Geophysics, chinese academy of sciences, Beijing 10002., {2.

Studies of ultra-high pressure metamorphic (UHP) rocks from china started in the 1980s. Progresses made so far are summarized as follows. (1) The Dabieshan-Sulu UHP belt became well-known in the world because that many new outcrops of UHP rocks were discovered. (2. Mineralogical evidence indicates that the continental crust rocks with low density could subduct down to depths of >2.0 km and experience UHP metamorphism. (3) UHP rocks from the Dabieshan-Sulu belt were dated as early Mesozoic when the Yangtze Craton subducted northward beneath the Sino-Korean Craton. (4) Fluids were not active, and oxygen isotope composition of meteoric water could be preserved during UHP metamorphism, as is evidenced by O-, C-, and H- isotope data. (5) A multistage model is suggested to explain the exhumation of the UHP terrain. Some hotly debated issues are summarized.

关键词： UHP rock ADVANCES STUDY OF china’S ULTRAHIGH-PRESSURE METAMORPHIC ROCKS IN THE PAST 15 YEARS Wang

Discussion on exploitation of mineral resources and ecological environmental issues in Wenquan, Wushan

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Acta Geochimica 2006年第S1期 44-45页

作者： Zhenming WEI1,2. Guodong ZHENG1,2. Yaling CHOU1,2.1 institute for Geological Research, chinese academy of sciences, Lanzhou 73000, {2. 2.State Key Laboratory of Frozen Soil Engineering, Cold and Arid Regions Environmental and Engineering Research institute, chinese academy of sciences, Lanzhou 73000, {2.

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芋螺毒素研究进展

生物化学与生物物理进展 2003年第4期30卷 537-545页

作者：王承忠蒋辉戚正武中国科学院上海生命科学研究院生物化学与细胞生物学研究所

芋螺毒素是近年来国际上的一个研究热点 .它属于一类海洋生物活性多肽 ,多数由 12. 4 6个氨基酸残基所组成 ,能特异性地作用于体内各种离子通道和细胞膜上神经递质和激肽的受体 .具有分子质量小、结构多样、作用靶点广泛、功能专一、... 详细信息

芋螺毒素是近年来国际上的一个研究热点 .它属于一类海洋生物活性多肽 ,多数由 12. 4 6个氨基酸残基所组成 ,能特异性地作用于体内各种离子通道和细胞膜上神经递质和激肽的受体 .具有分子质量小、结构多样、作用靶点广泛、功能专一、组织特异性强等优点 ,因而较之其他生物来源的活性多肽有更多的优越性 .芋螺毒素是一待挖掘的“富矿区” ,可作为体内一些具有重要生理功能靶点的探针和“解密器” ,亦可作为新药的先导化合物或直接开发成新药。

关键词：芋螺毒素活性多肽离子通道神经递质拮抗剂激动剂