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The enhancement of astrocytic-derived monocyte chemoattractant protein-1 induced by the interaction of opiate and HIV tat in HIV-associated dementia

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Journal of Pharmaceutical Analysis 2009年第4期21卷 277-281页

作者： Xiao Han Biomedical Experimentation,school of Basic Medical sciences,Peking University Health Science Center,{2. 100191,china BiomedicalExperimentation SchoolofBasicMedicalSciencesPekingUniversityHealthScienceCenterBeijing100191China

HIV-associated dementia(HAD)is a public health problem and is particularly prevalent in drug *** neuropathogenesis of human immunodeficiency virus(HIV)infection involves a complex cascade of inflammatory events,including monocyte/macrophage infiltration in the brain,glial immune activation and release of neurotoxic *** these events,astrocytic-derived monocyte chemoattractant protein-1(MCP-1)plays an important role,whose release is elevated by HIV transactivator of transcription(HIV tat)and could be further elevated by *** review will also consider some critical factors and events in MCP-1 enhancement induced by the interactions of opiate and HIV tat,including the mediating role of mu opioid receptor(MOR)and CCR2.as well as the possible signal transduction pathways within the ***,it will make some future perspectives on the exact pathways,new receptors and target cells,and the vulnerability to neurodegeneration with HIV and opiates.

关键词： dementia HIV transactivator of transcription astrocyte morphine monocyte chemoattractant protein-1

Dynamic expression pattern of GSK3βand its phosphorylation form in mouse olfactory bulb

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Dynamic expression pattern of GSK3βand its phosphorylation ...

2.12.海内外华人神经科学会议

作者： Zhi-Xiang Xu~(1 3) Guo Chen~4 Xiao-Ping Rao~(1 3) Rui-Qi Wu~(1 3) Fu-Qiang Xu~(1 2.*) 1.State Key Laboratory of Magnetic Resonance Atomic and Molecular Physics Wuhan Institute of Physics and Mathematics Chinese academy of sciences Wuhan 430071 {2. 2.Division of Biomedical Photonics Wuhan National Laboratory of Optoelectronics Wuhan 430074 {2. 3.graduate University of Chinese academy of sciences beijing 100049 {2. 4.College of Life sciences Wuhan University Wuhan 430071 {2..

＜正＞Glycogen synthase kinase-3β（GSK3β）,a multifaceted kinase highly expressed in mammal brain,whose activity is regulated by tyrosine（stimulatory） and serine（inhibitory） phosphorylation,direct physical *** studies suggested that GSK3βacts as an integrating protein in many processes during neurodevelopment for its critical role in Wnt,RTK,Notch and Shh signal ***,we used immunohistochemistry and western blot to study GSK3βand its different phosphorylation form in different developmental stages of mouse olfactory *** found that the early developmental olfactory bulb showed highly GSK3βactivity,then decreased in *** also found that when inhibited GSK3βactivity with TDZD-8,granule cells showed delay maturation and the diameter of glomeruli were significant *** results showed that the activity of GSK3βis essential for the olfactory bulb development.

关键词： GSK3β factory bulb development TDZD-8

遥感和GIS技术支持下的岷江上游15年土地利用/土地覆被动态变化研究

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水土保持学报 2003年第4期17卷 153-156页

作者：李爱农周万村江晓波中国科学院成都山地灾害与环境研究所

在遥感和GIS技术支持下,详细研究了岷江上游的土地利用/土地覆被状况及其1986～2.00年的时空动态变化及其驱动力影响。作者认为,必须在提高全民的环护意识以及相应政策、法规的制定和执行的前提下,加大产业结构调整,依靠科技创新,寻找... 详细信息

在遥感和GIS技术支持下,详细研究了岷江上游的土地利用/土地覆被状况及其1986～2.00年的时空动态变化及其驱动力影响。作者认为,必须在提高全民的环护意识以及相应政策、法规的制定和执行的前提下,加大产业结构调整,依靠科技创新,寻找新的经济增长点,切实增加农民收入,建立区域外补偿机制,保护该地区有限的珍贵林业资源,恢复其长江上游的生态屏障作用,实现国土资源的可持续利用。

关键词：遥感技术 GIS技术岷江上游土地利用土地覆被动态变化地理信息系统驱动力补偿机制科技创新林业资源保护

Analysis of junction temperatures in high-power GaN-based LEDs

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中国科学:技术科学 2010年第2期 199-199页

作者： JIANG YuXuan1, LI Zheng1, SUN YongJian1, YU TongJun1*, CHEN ZhiZhong1, ZHANG GuoYi1, ZHANG GuangChen2.& FENG ShiWei2.1 State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, school of Physics, Peking University, beijing 100871,{2. 2.school of Electronic Information & Control Engineering, beijing University of Technology, beijing 10012.,{2.

We presented the analysis of the incomplete conduction in bonding medium in high power GaN-based light-emitting diode (LED) packages. A numerical study was carried out with parametric model to understand the junction temperature variation due to bonding medium defects. Transient thermal measurement was performed to evaluate LED's junction temperature. Thermal resistance from chip to lead frame was 2. K/W in our sample LED. It was suggested that only 60% of the surface area of the bonding medium was involved in the thermal conduction. This result was also supported by the SEM image. Blocking of thermal path induced by ineffective area of the bonding medium was regarded as a factor of its thermal resistance. Thus, the effective area of the bonding medium should be included in the FEM model and considered as another important factor in high power LED's thermal management.

关键词： junction temperature bonding medium FEM simulation effective area

Assessment of candidate plant DNA barcodes using the Rutaceae family

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Science china(Life sciences) 2010年第6期53卷 701-708页

作者： LUO Kun1,2.CHEN ShiLin1,CHEN KeLi2.SONG JingYuan1,YAO Hui1,MA XinYe1,ZHU YingJie3,PANG XiaoHui1,YU Hua1,LI XiWen1,4 & LIU Zhen2.1Institute of Medicinal Plant Development,Peking Union Medical College,Chinese academy of Medical sciences,{2. 100193,china 2.ollege of Pharmacy,Hubei University of Chinese Medicine,Wuhan 430061,china 3school of Bioscience and Engineering,Southwest Jiaotong University,Chengdu 610031,china 4Department of Chemistry,Tsinghua University,{2. 100084,china Institute of Medicinal Plant Development Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100193 China

DNA barcoding is a rapidly developing frontier technology that is gaining worldwide ***,seven regions (psbA-trnH,matK,ycf5,rpoC1,rbcL,ITS2.and ITS) with potential for use as DNA barcodes were tested for their ability to identify 300 samples of 192.species from 72.genera of the family *** evaluate each barcode’s utility for species authentication,PCR amplification efficiency,genetic divergence,and barcoding gaps were *** found that the ITS2.region exhibited the highest inter-specific divergence,and that this was significantly higher than the intra-specific variation in the "DNA barcoding gap" assessment and Wilcoxon two-sample *** ITS2.locus had the highest identification efficiency among all tested *** a previous study,we found that ITS2.was able to discriminate a wide range of plant taxa,and here we confirmed that ITS2.was also able to discriminate a number of closely related ***,we propose that ITS2.is a promising candidate barcode for plant species identification.

关键词： DNA barcoding ITS2 Rutaceae identification

Adoption of internet banking:An empirical study in china

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Adoption of internet banking:An empirical study in China

第六届（2.11）中国管理学年会——市场营销分会场

作者： Ma Zhengwei school of Business Administration,china University of Petroleum({2.),{2.,china

The propose of the paper is to analyze factors of customer service quality that could influence internet banking customer satisfaction in the Chinese commercial banking ***,the paper also tries to explain the relationship between customer service quality and customer satisfaction,and to find some major variables for keeping high level internet banking customer *** data demonstrated that customer service quality have direct and significant effect to internet banking quality in the Chinese commercial banking *** this,the authors found that customer service quality is positively related to internet banking customer ***,it is observed that price,personalization and customization,reputation are key factors to affect customer satisfaction in the internet banking *** the validation of measurement scales,the hypothesis is contrasted through structural *** authors validate the hypothesis and a measurement *** paper proposes a model for analyzing empirically the link between customer service quality and internet banking customer satisfaction in Chinese internet banking industry.

关键词： internet banking customer satisfaction customer service quality

FUZZY OPTIONS INDUCED BY THE FAMILY OF λ-FUZZY MEASURES AND CHOQUET INTEGRALS

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FUZZY OPTIONS INDUCED BY THE FAMILY OF λ-FUZZY MEASURES AND...

第11届国际模糊系统协会世界大会

作者： Liyan Han Juan Zhou Chengli Zheng school of Economics and Management Beihang University beijing 100083 {2. graduate school of Business (PKU SZ) Peking University Shenzhen 518055 {2.

＜正＞ Classical option pricing formulas are facing challenges such as heterogeneity of investors. This paper reveals non-identical rationality with a family ofλ-fuzzy measures and deduces fuzzy price of the option. Further we discuss properties of fuzzy option hedge ratio. We also attempt to apply the fuzzy option to portfolio insurance and credit risk measure. This method could benefit the research of behavioral economics.

关键词： fuzzy options λ-fuzzy measures Choquet integrals heterogeneity

CLIFFORD MARTINGALES Φ-EQUIVALENCE BETWEEN S(f)AND f

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Chinese Annals of Mathematics,Series B 1994年第4期15卷 507-516页

作者： LONGRULIN QIANTAO schoolofInformationScienceandTechnology TheFlindersUniversityofSouthAustralia. InstituteofMathematics AcademisSinicaBeijing100080China

Required by the application in the investigation of the Cauchy integral operators on Lipschitzsurfaces, the classical martingales are generalized to ones defined with respect to Clifford algebravalued measures. Meanwh... 详细信息

关键词： Clifford algebra Martingale Square function Maximal function Good λ-inequality.

基于小波变换的MPSK信号符号速率估计算法

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数据采集与处理 2009年第B10期24卷 167-170页

作者：高勇黄振陆建华清华大学电子工程系北京100084 清华大学航天航空学院北京100084

在非合作MPSK信号调制方式识别和盲解调过程中,符号速率的估计是一个重要环节。本文根据morlet小波函数的时频特征以及MPSK信号的时频分布,提出了一种基于morlet小波变换的MPSK信号符号速率估计算法。仿真结果表明,与现有算法相比,该算... 详细信息

在非合作MPSK信号调制方式识别和盲解调过程中,符号速率的估计是一个重要环节。本文根据morlet小波函数的时频特征以及MPSK信号的时频分布,提出了一种基于morlet小波变换的MPSK信号符号速率估计算法。仿真结果表明,与现有算法相比,该算法对载频估计误差不敏感,具有更低的信噪比门限,也更逼近CRLB曲线。

关键词：符号速率小波变换 MPSK信号