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Work-family conflict and job burn-out among chinese doctors:the mediating role of coping styles

General Psychiatry 2018年第4期31卷 24-30页

作者： Ling Chen Junjun Liu Hailong Yang Hui Ma Hui Wang Yun Huang Hao Cheng Dianzhen Tang Miao Liu Houyuan Luo Haitao Qu Diwen Shen Ning Zhang department of Clinical Psychology Jiangsu Province Geriatric InstituteNanjingChina department of Psychiatry Nanjing Meishan HospitalNanjingChina department of Clinical Psychology Nanjing Drum Tower Hospital Clinical College of Nanjing Medical UniversityNanjingChina department of Clinical Psychology Nanjing Brain Hospital Affliated to Nanjing Medical UniversityNanjingChina department of Neurology Lianyungang hospital of {2. chinese Medicine LianyungangChina medical Insurance Audit department Medical Insurance Management and Service BureauHangzhouChina Educational and Counseling department of Mental Health Nanjing University of Posts and TelecommunicationsNanjingChina Customer Service department Tuniu CorporationNanjingChina College of Education Weifang University of Science and TechnologyHuaifangChina department of Educational Psychology University of AlbertaEdmontonAlbertaCanada Institute of Health Management Jiangsu Jiankang Vocational CollegeNanjingChina

Background Burn-out among doctors threatens their own health, and that of their patients. To identify risk factors of the doctor burn-out is vital to improving their health and increasing the quality of healthcare services. This study aims to explore the relationship between work-family confict （WFC） and burn-out among chinese doctors and the mediating role of coping styles in this *** A cross-sectional survey was conducted in China, with a questionnaire packet which consisted of the chinese Maslach Burnout Inventory （CMBI）, WFC Scale and the Simplifed Coping Style Questionnaire （SCSQ）. A total of 2.30 doctors participated in the survey. Correlation analysis was performed to explore the relationship between CMBI, WFC and SCSQ scores. A linear regression model was set to determine the mediating role of coping styles on the relationship between WFC and *** Doctors who had higher scores on work interfering with family confict, reported more emotional exhaustion （r=0.514, P〈0.001） and had a sense of accomplishment （r= 0.149, P〈0.001）. Simultaneously, family interfering with work （FIW） was positively associated with all dimensions of burn-out （r=0.2.3, 0.504, 0.088, respectively, P〈0.001）. Coping styles had partial, complete and even mediating effects on the relationship between WFC and burn-out among chinese *** WFC was correlated with burn-out, and coping style was a mediator in this relationship among chinese doctors. Coping style was a positive resource against burn-out.

关键词： Work-family confict and job burn-out among chinese doctors the mediating role of coping styles

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氢氧化钙对乳牙感染根管作用的研究

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上海口腔医学 2003年第2期12卷 109-111页

作者：赵今李胜华朱震宏新疆医科大学一附院口腔科新疆乌鲁木齐830002 青岛海洋大学校医院口腔科山东青岛266003 新疆医科大学一附院检验科新疆乌鲁木齐830002

目的探讨氢氧化钙用作乳牙感染根管消毒剂的效果。方法通过临床12.例患者的对照观察,X线片以及实验细菌学检验,对氢氧化钙用于乳牙感染根管与常规使用的甲醛甲酚(FC)、樟脑酚消毒剂作对比,比较三种消毒剂消毒前后根管内细菌的变化以及... 详细信息

目的探讨氢氧化钙用作乳牙感染根管消毒剂的效果。方法通过临床12.例患者的对照观察,X线片以及实验细菌学检验,对氢氧化钙用于乳牙感染根管与常规使用的甲醛甲酚(FC)、樟脑酚消毒剂作对比,比较三种消毒剂消毒前后根管内细菌的变化以及治疗后的反应。结果乳牙感染根管中的细菌与成人恒牙感染根管相似,是以厌氧菌为主的混合感染。氢氧化钙对乳牙感染根管有很强的杀菌、抑菌作用,优于樟脑酚,与FC相似,但氢氧化钙对根尖周组织无刺激性及不良作用;而且对儿童尤其安全、有效,临床效果肯定。结论氢氧化钙是安全、有效而理想的乳牙感染根管的消毒药物。

关键词：氢氢化钙乳牙感染根管消毒剂甲醛甲酚樟脑酚厌氧菌

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心脏疾病中西医结合康复指南

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上海医药 2024年第17期45卷 15-28页

作者：上海市康复医学会肌肉骨骼中西医结合康复专业委员会《心脏疾病中西医结合康复指南》编写组上海中医药大学附属龙华医院康复医学科李学飞刘丹王诗云袁薇娜陈苹华李攀李芳芳陈晨陈倩李方语郭苏霞胡志俊不详上海中医药大学附属龙华医院康复医学科上海200032

心血管疾病是全球人类死亡的主要原因之一。对心脏疾病患者进行全阶段的康复干预是临床面临的一项重大挑战。中医药在疾病康复方面具有独到的优势,但目前国内尚无对心脏疾病的中西医结合康复方案。为此,上海市康复医学会肌肉骨骼中西医... 详细信息

心血管疾病是全球人类死亡的主要原因之一。对心脏疾病患者进行全阶段的康复干预是临床面临的一项重大挑战。中医药在疾病康复方面具有独到的优势,但目前国内尚无对心脏疾病的中西医结合康复方案。为此,上海市康复医学会肌肉骨骼中西医结合康复专业委员会组织有关专家,结合近年来国内外相关临床指南,经反复讨论、论证,制定了《心脏疾病中西医结合康复指南》,以期用于指导和规范心脏疾病中西医结合康复实践。

关键词：心脏疾病康复中西医结合临床指南

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The relationship between HBV lamivudine resistance and HBV genotypes or basic core promoter mutations

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Hepatobiliary & Pancreatic Diseases International 2003年第1期2卷 85-89页

作者： Dong-Yao Zhou Lian-Ying Lin Hong Wang Jian-Sheng Huang the department of Clinical Laboratory Medicine, Guangdong Provincial hospital of {2. chinese Medicine, Guangzhou 51012., China Molecular Biology Diagnostic Center, First Military medical University, Guangzhou 510515, China department of Clinical Laboratory Medicine Guangdong Provincial Hospital of Traditional Chinese Medicine (TCM) Guangzhou 510120 China. zhoudongyao@***

OBJECTIVE: To investigate the relationship between HBV Iamivudine resistance and HBV genotypes or basic core promoter (BCP) mutations. METHODS: The common coated probes were synthesized according to the conserved regions of the preC gene of hepatitis B virus (HBV). Different colorized probes were chosen from the sequences of different genotypes of HBV (A to F), BCP and YMDD wild types and mutants, respectively. HBV DNA levels, HBV genotypes, BCP and YMDD resistants were analyzed by PCR microplate hybridization ELISA at the zero and 6th month after the patients were treated with lamivudine. RESULTS: HBV genotyping results showed that HBV types B, C, D accounted for about 30%, 36% and 2.% patients respectively. Thirteen BCP mutations (type B in 1 patient, type C in 8 and type D in 4) were found before treatment with lamivudine. HBV DNA levels were lower than 100 pg/ml in 2.patients anti higher than 100 pg/ml in 11. 9.4% of the HBV patients (5/43; type C in 3 and type D in 2. showed YMDD resistants and 4 BCP mutations at the same time. CONCLUSION: Oral treatment of lamivudine decreases the level of serum HBV DNA. The appearance of HBV YMDD resistants is related to certain HBV genotypes, and most of them are BCP mutations.

关键词： hepatitis B virus genotype mutation lamivudine resistant

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乳头溢液的诊断与中药治疗探讨

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华中科技大学学报（医学版） 2002年第5期31卷 589-590页

作者：张传芳华中科技大学同济医学院附属同济医院中医科武汉430030

对有乳头溢液的 87例女性患者排除由全身疾病引起乳头溢液后 ,全部病例经 B型彩色超声波及乳头分泌物涂片或针吸细胞学检查确诊 ,除 13例行手术治疗外 ,其余 74例随机分为治疗组 5 0例 ,对照组 2.4例 ,治疗组用中药治疗 ,对照组用维生... 详细信息

对有乳头溢液的 87例女性患者排除由全身疾病引起乳头溢液后 ,全部病例经 B型彩色超声波及乳头分泌物涂片或针吸细胞学检查确诊 ,除 13例行手术治疗外 ,其余 74例随机分为治疗组 5 0例 ,对照组 2.4例 ,治疗组用中药治疗 ,对照组用维生素 C及维生素 E治疗。两组病例均治疗 2.月为一个疗程。结果表明 :该组病例中乳腺增生症占6 7.82.% ,乳腺导管扩张症占 17.2.4 % ,导管内乳头状瘤占 11.4 9% ,乳腺癌占 3.4 5 %。乳头溢液以浆液性及混合性为主者多见于乳腺良性疾病。 3例乳腺癌及 10例导管内乳头状瘤均行手术治疗。非手术治疗患者用药一疗程后两组疗效有显著性差异 (P<0 .0 1) 。

关键词：乳头溢液乳腺增生症乳腺肿瘤乳腺导管扩张症中草药

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Cadaveric Study of Nerves SuPPlying the Membranous Urethra

Cadaveric Study of Nerves SuPPlying the Membranous Urethra

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第十六届全国泌尿外科学术会议

作者： Lu-Jie Song~1,Hong-Kai Lu~2.Yue-Min Xu~1 1 department of Urology,Affiliated Sixth PeoPle’s hospital, Shanghai Jiaotong University,Shanghai 2.02.3,China. 2.department of Urology,Weifang traditional chinese Medicine hospital,Shandong 2.1041,China

Aims:To better understand the anatomy of the region of the male membranous urethra in order to Preserve continence during radical cystectomy and ***: Cadaveric dissections of 15 male sPecimens were undertaken to inves...

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异常黑胆质型痴呆证病结合模型建立及方药干预实验

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科技导报 2012年第33期30卷 50-55页

作者：帕丽丹·吾术尔哈木拉提·吾甫尔热娜古丽·艾则孜努尔买买提·艾买提新疆医科大学附属中医医院心身科新疆医科大学维吾尔医学院

为了建立阿尔茨海默病(AD)异常黑胆质证病结合大鼠模型,并观察维药异常黑胆质成熟剂对其影响,采用经典方法建立异常黑胆质证模型,随后将凝集态β-淀粉样蛋白1-40(β-Amyloid1-40,Aβ1-40)定位注射到双侧海马,建立病证结合模型;应用异常... 详细信息

为了建立阿尔茨海默病(AD)异常黑胆质证病结合大鼠模型,并观察维药异常黑胆质成熟剂对其影响,采用经典方法建立异常黑胆质证模型,随后将凝集态β-淀粉样蛋白1-40(β-Amyloid1-40,Aβ1-40)定位注射到双侧海马,建立病证结合模型;应用异常黑胆质成熟剂方药干预,观察各组体征变化,通过Morris水迷宫和跳台仪进行行为学测试,比较各组学习记忆能力的改变。结果表明,异常黑胆质证组和AD异常黑胆质证病结合组表现出饮水量增加(P<0.01),饮食量增加(P<0.01),体重减轻(P<0.01)等;AD组、异常黑胆质证组、AD异常黑胆质证病结合组学习记忆力降低(P<0.05);AD异常黑胆质证病结合组+异常黑胆质成熟剂干预组异常黑胆质证生物表征和学习记忆力均有所改善(P<0.05)。研究表明,异常黑胆质成熟剂对AD异常黑胆质证病结合组大鼠的生物表征及学习记忆能力均有一定改善作用。

关键词：阿尔茨海默病异常黑胆质证异常黑胆质成熟剂学习记忆

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Enhancement of Extracts from Celastrus orbiculatus on Maturation and Function of Dendritic Cells in vitro and in vivo

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chinese Herbal Medicines 2010年第3期2卷 195-203页

作者： QIAN Ya-yun1, ZHANG Hua2. YUAN Lin1,3, HOU Ying1, LIU Wei-wei1, LIU Yan-qing1 1. Institute of traditional chinese Medicine & Western Medicine, Yangzhou University, Yangzhou 2.5009, China 2. {2. of nursing, medical College, Yangzhou University, Yangzhou 2.5009, China 3. {2. of Image, 97th hospital of People’s Liberation Army, Xuzhou 2.1000, China Institute of traditional chinese Medicine & Western Medicine Yangzhou UniversityYangzhou 225009China department of nursing Medical CollegeYangzhou UniversityYangzhou 225009China Institute of traditional chinese Medicine & Western Medicine Yangzhou UniversityYangzhou 225009China department of Image 97th Hospital of People's Liberation ArmyXuzhou 221000China

Objective To examine the immunoregulation of Celastrus orbiculatus extracts (COE), a traditional chinese medicine, on maturation and function of dendritic cells (DCs) in vitro and in vivo. Methods In vitro, after treated with COE in different nontoxic concentrations (0, 10, 2., 40, 80, and 160 μg/mL) for 5 d, the surface immunological molecules and cytokine secretion of mice bone marrow-derived DCs in response to COE were analyzed by flow cytometric analysis (FACS) and enzyme linked immunosorbent assay (ELISA), respectively. In vivo, mouse hepatoma cells (Hepa1-6, 1 × 106) were injected sc and were treated with different dosages of COE (10, 2. or 40 mg/kg/d). Effects on tumor growth were determined by tumor volume and histology analysis after 2. d administration of COE. The relative proportions of mature DCs and CD8+ T cells were measured in mononuclear cells that had been isolated from spleen by FACS. Results COE stimulated IL-2.and IFN-γ secretion of DCs, simultaneously enhanced the maturation of DCs by enhancing immunological molecule (CD40, CD80, CD86, H-2.b, and I-Ab) expression in a dose-dependent manner. Furthermore, the chemotactic responses of DCs were significantly higher in COE-treated than untreated DCs, in association with higher chemokine receptor 7 expression. Furthermore, COE increased DCs produce IFN-γ and IL-2.in a dose-dependent manner when the concentration of COE less than 40 μg/mL, decreased DCs produce IL-10 and IL-4 also in a dose-dependent manner. In in vivo studies, COE can not only suppress growth of malignant hepatocellular carcinomas but also stimulate maturation of DCs, associated with strongly enhanced CD8+ CTL responses. Conclusion These data provide new insight into the mechanism of action of COE and indicate that the stimulation of maturation and function of DCs by COE contributes to its immunoregulatory effects.

关键词： antitumor Celastrus orbiculatus dendritic cell immunoregulation

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细胞电泳研究冠心病临床与实验的初步观察

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北京医学 1979年第3期 148-150页

作者： department of Biochemistry, Beijing Institute of traditional {2. Medicine Coronary Heart Disease Group of Beijing traditional {2. medical hospital 北京市中医研究所生化研究室北京市中医医院冠心病组

本文采用方形毛细管小室的细胞电泳装置,测定了44例冠心病患者的红细胞电泳率,也看到患者红细胞电泳率(0.82.0.11微米/秒/伏特/厘米)比正常人红细胞电泳率(1.2.±0.06)为慢。本文还观察了中药方剂二参通脉针对实验动物的红细胞电泳率... 详细信息

本文采用方形毛细管小室的细胞电泳装置,测定了44例冠心病患者的红细胞电泳率,也看到患者红细胞电泳率(0.82.0.11微米/秒/伏特/厘米)比正常人红细胞电泳率(1.2.±0.06)为慢。本文还观察了中药方剂二参通脉针对实验动物的红细胞电泳率的影响。选用家犬作实验动物,二参通脉针系本所中药研究室制的(每毫升含生药1 mg),以每公斤体重0.31毫升剂量,股静脉给药,于给药前、后10分钟、30分钟分别取股动脉血2.升(肝素抗凝),进行红细胞电泳率测定。发现注射二参通脉针前后,红细胞电泳率有显著不同。(结果:给药前0.96±0.72.后10分钟为1.11±0.2.,30分钟为1.2.±0.16)。看来二参通脉针对红细胞电泳率有明显的加快作用。

关键词：红细胞电泳率实验动物冠心病人通脉二参

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Hepatocellular carcinoma HepG2.cell apoptosis and caspase-8 and Bcl-2.expression induced by injectable seed extract of Coix lacryma-jobi

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Hepatobiliary & Pancreatic Diseases International 2011年第3期10卷 303-307页

作者： department of General Surgery (Lu Y and Zhang BY),department of Bio-Information (Jia ZX),Affiliated {2. College hospital,Qingdao University,Qingdao 2.6003,China Shanghai Jiaotong University School of Medicine,Shanghai 2.002.,China (Wu WJ) department of Medicine,Heze {2. College,Heze 2.4000,China (Lu ZQ) department of General Surgery Affiliated Medical College Hospital Qingdao University department of Bio-Information Affiliated Medical College Hospital Qingdao University

BACKGROUND:Many chinese herbs,especially herbal injections,have been shown to have anti-tumor effects in recent ***,since most reports focus on the clinical effectiveness of these herbs,their mechanisms of action are not well *** this study,we assessed apoptosis in the hepatocellular carcinoma (HCC) cell line HepG2.induced by an injectable extract from the seed of Coix lacryma-jobi (Semen coicis,SC),and monitored the expression of Bcl-2.and ***:Injectable SC was applied to HepG2.cells at different concentrations and the cells were collected 12.2. and 48 hours later.5-fluorouracil was used as a positive control group,and fluorescence-activated cell-sorting cytometry was used to measure the apoptosis rate of HepG2.cells and the expression of Bcl-2.and caspase-8 ***:SC induced apoptosis in HepG2.cells in a concentration and time-dependent manner,and the expression of caspase-8 was elevated and ***,it did not significantly influence the expression of ***:Injectable SC may induce apoptosis in HCC cells by regulating the expression of caspase-8.

关键词： Semen coicis traditional chinese medicine Bcl-2 caspase-8 HepG2.cells apoptosis

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