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A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease

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Neural Regeneration Research 2024年第2期19卷 324-330页

作者： xi Chen Yuhu Zhang department of Neurology Guangdong Neuroscience InstituteGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina Shantou university Medical College ShantouGuangdong ProvinceChina

The dichotomized brain system is a concept that was generalized from the‘dual syndrome hypothesis’to explain the heterogeneity of cognitive impairment,in which anterior and posterior brain systems are independent but partially *** dopaminergic system acts on the anterior brain and is responsible for executive function,working memory,and *** contrast,the cholinergic system acts on the posterior brain and is responsible for semantic fluency and visuospatial *** from dopaminergic/cholinergic imaging or functional neuroimaging has shed significant insight relating to the involvement of the cerebellum in the cognitive process of patients with Parkinson’s *** research has reported evidence that the cerebellum receives both dopaminergic and cholinergic ***,whether these two neurotransmitter systems are associated with cognitive function has yet to be fully ***,the precise role of the cerebellum in patients with Parkinson’s disease and cognitive impairment remains ***,in this review,we summarize the cerebellar dopaminergic and cholinergic projections and their relationships with cognition,as reported by previous studies,and investigated the role of the cerebellum in patients with Parkinson’s disease and cognitive impairment,as determined by functional *** findings will help us to understand the role of the cerebellum in the mechanisms underlying cognitive impairment in Parkinson’s disease.

关键词： anterior brain system cerebellum cholinergic cognitive impairment dopaminergic dual syndrome hypothesis neuroimage neurotransmitter Parkinson’s disease posterior brain system therapeutic targets

LA-ICP-MS dating of Zhangjiakou Formation volcanic rocks in the Zhangjiakou region and its geological significance

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Progress in Natural Science:Materials International 2008年第8期18卷 975-981页

作者： Hong Zhang a,b,*, Mingxin Wang a, xiaoming Liu b a College of Mechanical and Energy Engineering, Jiangsu Polytechnic university, Baiyun District, Changzhou, Jiangsu 2.3016, china b Key Laboratory of Continental Dynamics, {2. of geology, northwest university, xi’an 710069, china College of Mechanical and Energy Engineering Jiangsu Polytechnic University Baiyun District Changzhou Jiangsu 213016 China Key Laboratory of Continental Dynamics Department of Geology Northwest University Xi’an 710069 China

The geological cross section of the Zhangjiakou Formation is originally established in the Zhangjiakou region. From the dating of four samples from typical cross sections of the Zhangjiakou Formation in the Zhangjiakou region, the age range is found to be mainly from 143.0 ± 3.7 Myr to 136.1 ± 1.4 Myr, which almost equals the sum of the age range of the Zhangjiakou Formation (136-135 Myr) and that of the Tuchengzi Formation (143-136 Myr) in the Luanping region, and the Zhangjiakou and Tuchengzi Formations in Zhangjiakou-Luanping of North Hebei are found to be conformable. The evidence above indicates that the Zhangjiakou and Tuchengzi Formations, which are distributed in Zhangjiakou-Luanping, were formed under the same geological setting. Volcanic activity was earlier and longer (143-136 Myr) in the western region (Zhangjiakou) than that in the eastern region (Luanping). The "Zhangjiakou Formation"in Chengde and Pingquan formed in the period in which the Yixian Formation in West Liaoning formed, so should be renamed the Yixian Formation.

关键词： Zhangjiakou Formation Volcanic rocks LA-ICP-MS Dating Zhangjiakou region

Bio-screening and quantification of methyl paraben in vinegar and coconut juice separated by HPTLC

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Food Science and Human Wellness 2024年第3期13卷 1602-1607页

作者： Yisheng Chen xingjun xi College of Food Science and Engineering Shanxi Agricultural UniversityTaigu 030801China Insitute of Food Nutrition and Safety Shanxi Agricultural UniversityTaiyuan 030031China Institute of Agricultural Food Standardization China National Institute of StandardizationBeijing 100191China

As a widely used food preservative,methyl paraben was experimentally evidenced with serious hormonelike adverse ***,a high performance thin-layer chromatography platformed bioluminescent bioautography and image analysis for the selective quantification and confirmation of methyl paraben was proposed and validated in vinegar and coconut ***,the detectability of the bioautography to the analyte on different layer materials was estimated,revealing that normal silica gel was the best *** that,the liquid of sample extract and working solution were separated to overcome the background noises due to co-extracted *** separation result was then coupled to the optimized bioautography,enabling instant and straightforward screening of the targeted *** accurate quantification,bioluninescent inhibition pattern caused by the analyte was processed by image analysis,giving useful sensitivity(LOD>16 mg/kg),precision(RSD2.2.).Finally,the suspected result was confirmed by determining its MS fingerprint,further strengthening the reliability of screening.

关键词： High performance thin-layer chromatography Bio-screening Bioluminescence Image analysis Methyl paraben

Timing and geochemical characters of the Sanchazi magmatic arc in Mianlüe tectonic zone,South Qinling

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Science china Earth Sciences 2004年第4期47卷 317-328页

作者： LI Shuguang1, HOU Zhenhui1, YANG Yongcheng2. SUN Weidong1,1), ZHANG Guowei3, & LI Qiuli1 1. School of Earth and Space Sciences,university of Science and Technology of china ,Hefei 2.002.,{2. 2. Regional Geological Survey Team of Shaanxi Province,xianyang 712.00, china 3. department of geology, northwest university,xi抋n 710069, china Present address: Max-Planck-Institut f. Chemie Postfach 3060 55020 Mainz Germany School of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China Regional Geological Survey Team of Shaanxi Province Xianyang 712000 China department of geology Northwest University Xi’an 710069 China

The Sanchazi mafic-ultramafic complex in Mianlüe tectonic zone,South Qinling can be subdivided into two blocks,*** paleo-magmatic arc and Zhuangkegou paleo-oceanic crust fragment (ophiolite).The Sanchazi paleo-magmatic arc is mainly composed of ande-site,basaltic and basalt-andesitic gabbro(or diorite),andesitic dyke,plagiogranite and minor ul-tramafric rocks,which have typical geochemical features of island arc volcanic rocks,such as high field strength element(***,Ti)depletions and lower Cr,Ni *** Light rare earth element (LREE) and K enrichments of these rocks and zircon xenocrystals of 900 Ma from plagiogranite suggest that this magmatic arc was developed on the South active continental margin of the South Qinling *** U-Pb age of (300±61) Ma for zircons from plagiogranite in-dicates that the Mianlüe paleo-oceanic crust was probably subducted underneath the South Qinling micro-continent in *** is consistent with the formation time (309Ma) of the Huwan eclogite originating form oceanic subduction in Dabie Mountains,suggesting that the Mianlüe paleo-ocean probably extended eastward to the Dabie Mountains in *** high-Mg adakitic rocks in Sanchazi paleo-magmatic arc suggest thet the subducted oceanic crust was relatively young (2.Ma) and hot.

关键词： Qinling orogen, magmatic arc, U-Pb zircon age, ophiolite complex.

Determination of tectonic background for sedimentary basin from sandstone geochemistry

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Chinese Science Bulletin 1998年第14期43卷 1191-1196页

作者： SHAO Lei 1, K. Stattegger 2.and LI Wenhou 3 1. Laboratory of Marine geology, Tongji university, Shanghai 2.0092.{2. 2. Geological and Paleontological Institute, university of Kiel, 2.118 Kiel, Germany 3. department of geology, northwest Unive Laboratory of Marine geology Tongji University Shanghai China Geological and Paleontological Institute University of Kiel Kiel Germany department of geology Northwest University Xi’an China

The chemical composition of sedimentary rocks is mainly controlled by source rocks. Through examining chemical composition of terrigenous rocks, the tectonic evolution of a sedimentary basin can be modeled. The Turpan Basin belongs to a continental sedimentary basin and its source rocks are derived from the upper continental crust.

关键词： sedimentary rock geochemistry basin analysis Turpan Basin.

Parameter Estimation of Sub-/Super-synchronous Oscillation Based on Interpolated All-phase Fast Fourier Transform with Optimized Window Function

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1031-1041页

作者： Bo Sun xi Wu xi Chen Zixiao Zou Qiang Li Bixing Ren School of Electrical Engineering Southeast UniversityNanjingChina State Grid Jiangsu Electric Power Company Limited Research Institute NanjingChina

In recent years,with increasing amounts of renew-able energy sources connecting to power grids,sub-/super-syn-chronous oscillations(SSOs)occurred more *** to the time-variant nature of SsO magnitudes and frequencies,as well as the mutual interferences among SsO modes with close frequencies,the accurate parameter estimation of SsO has be-come a particularly challenging *** solve this issue,this paper proposes an improved spectrum analysis method by im-proving the window function and a spectrum correction method to achieve higher ***,by aiming at the sidelobe characteristics of the window function as evaluation criteria,a combined cosine function is optimized using a genetic algorithm(GA).Furthermore,the obtained window function is self-con-volved to extend its excellent characteristics,which have better performance in reducing mutual interference from other SSO ***,a new form of interpolated all-phase fast Fourier transform(IpApFFT)using the optimized window func-tion is proposed to estimate the parameters of *** meth-od allows for phase-unbiased estimation while maintaining algo-rithmic simplicity and *** performance of the pro-posed method is demonstrated under various conditions,com-pared with other estimation *** results vali-date the effectiveness and superiority of the proposed method.

关键词： Sub-/Super-synchronous oscillation(SSO) window function parameter estimation interpolated all-phase fast Fourier transform(ApFFT)

An extended numerical model of the first exothermic peak for three dimensional printed cement-based materials

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Frontiers of Structural and Civil Engineering 2024年第1期18卷 80-88页

作者： Wei JIANG Wenqian LI xi CHEN School of Materials Science and Engineering Tongji UniversityShanghai 200092China School of Civil Engineering Tongji UniversityShanghai 200092China

The first exothermic peak of cement-based material occurs a few minutes after mixing,and the properties of three dimensional(3D)printed concrete,such as setting time,are very sensitive to *** this background,based on the classical Park cement exothermic model of hydration,we propose and construct a numerical model of the first exothermic peak,taking into account the proportions of C_(3)S,C_(3)A and quicklime in *** calculated parameters are calibrated by means of relevant published exothermic test *** is found that this developed model offers a good simulation of the first exothermic peak of hydration for C_(3)S and C_(3)A proportions from 0 to 100% of cement clinker and reflects the effect of quicklime content at 8%-10%.The unique value of this research is provision of an important computational tool for applications that are sensitive to the first exothermic peak of hydration,such as 3D printing.

关键词： 3D printed cement-based materials cement hydration the first exothermic peak liquid quick-setting agent numerical model

A new method to solve the Reynolds equation including mass-conserving cavitation by physics informed neural networks(PINNs)with both soft and hard constraints

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Friction 2024年第6期12卷 1165-1175页

作者： Yinhu xi Jinhui DENG Yiling LI School of Mechanical Engineering Anhui University of Science and TechnologyHuainan 232001China Ericsson AB Datalinjen 3Linköping 58330Sweden

In this work,a new method to solve the Reynolds equation including mass-conserving cavitation by using the physics informed neural networks(PINNs)is *** complementarity relationship between the pressure and the void fraction is *** are several difficulties in problem solving,and the solutions are ***,the difficulty for considering the pressure inequality constraint by PINNs is solved by transferring it into one equality constraint without introducing *** the void fraction inequality constraint is considered by using the hard constraint with the max-min ***,to avoid the fluctuation of the boundary value problems,the hard constraint method is also utilized to apply the boundary pressure values and the corresponding functions are ***,for avoiding the trivial solution the limitation for the mean value of the void fraction is *** results are validated against existing data,and both the incompressible and compressible lubricant are *** agreement can be found for both the domain and domain boundaries.

关键词： Reynolds equation mass-conserving cavitation physics informed neural networks hard constraints trivial solution

The essential ability of sparse reconstruction of different compressive sensing strategies

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Science china(Information Sciences) 2012年第11期55卷 2582-2589页

作者： ZHANG Hai1,2.LIANG Yong3,GOU HaiLiang1 & XU ZongBen1 1 Institute for Information and System Science,xi'an Jiaotong university,xi'an 710049,china 2.2. of Mathematics,northwest university,xi'an 710069,china 3university of Science and Technology,Macau 999078,china 1. Institute for Information and System Science Xi’an Jiaotong University Xi’an 710049 China2. Department of Mathematics Northwest University Xi’an 710069 China3. University of Science and Technology Macau 999078 China

We show the essential ability of sparse signal reconstruction of different compressive sensing strategies,which include the L1 regularization,the L0 regularization(thresholding iteration algorithm and OMP algorithm),the Lq(0 2.regularization can be taken as a representative of the Lq(0 2.2.regularization always yields the sparsest solutions and when 0 2.the performance of the regularizations takes no significant *** results of this paper provide experimental evidence for our previous work.

关键词： compressive sensing regularization sparsity L1/2.regularization