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The role of different cues in the brain mechanism on visual spatial attention

Progress in Natural Science:Materials International 2006年第10期16卷 1045-1050页

作者： SONG Weiqun, LUO Yuejia, CHI Song, JI Xunming, LING Feng, ZHAO Lun, WANG Maobin and SHI Jiannong ( Department of Rehabilitation, Xuanwu Hospital, Capital university of Medical Science, Beijing 100053, china State Key Laboratory of Cognitive Neuroscience and Learning, Beijing {2. university, Beijing 100875, china School of Psychology, Southwest university, Chongqing 400715, china Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of sciences, Beijing 100101, china Department of Neurology, Affiliated Hospital of Qingdao university, Medical college, Qingdao 2.6003, china Department of Neurology, Xuanwu Hospital, Capital university of Medical Science, Beijing 100053, china Institute of Linguistics, Xuzhou {2. university, Xuzhou 2.1116, china) [a]Department of Rehabilitation Xuanwu Hospital Capital University of medical science Beijing China [b]State Key laboratory of Cognitive Neuroscience and Learning Beijing Normal University Beijing China [c]School of Psychology Southwest University Chongqing China [d]Key Laboratory of Mental Health Institute of Psychology Chinese Academy of Science Beijing China [e]Department of Neurology Affiliated Hospital of Qingdao University Medical College Qingdao China [f]Department of Neurology Xuanwu Hospital Capital University of Medical Science Beijing China [g]Institute of Linguistics Xuzhou Normal University Xuzhou China

The visual spatial attention mechanism in the brain was studied in 16 young subjects through the visual search paradigm of precue-target by the event-related potential (ERP) technique, with the attentive ranges cued by different scales of Chinese character and region cues. The results showed that the response time for Chinese character cues was much longer than that for region cues especially for small region cues. With the exterior interferences, the target stimuli recognition under region cues was much quicker than that under Chinese character cues. Compared with that under region cues, targets under Chinese character cues could lead to increase of the posterior P1, decrease of the N1 and increase of the P2. It should also be noted that the differences between region cues and Chinese character cues were affected by the interference types. Under exterior interferences, no significant difference was found between region cues and Chinese character cues; however, it was not the case under the interior interferences. Considering the difference between the exterior interferences and the interior interferences, we could conclude that with the increase of difficulty in target recognition there was obvious difference in the consumption of anterior frontal resources by target stimuli under the two kinds of cues.

关键词： visual spatial attention cue scale event-related potential (ERP) Chinese character cues region cues.

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The role of CpG Motifs in S-1 fragment DNA Vaccines for SARS Coronavirus

The role of CpG Motifs in S-1 fragment DNA Vaccines for SARS...

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2.05全国第二届核酸疫苗研讨会

作者： TANG Yi HE Hong-Xuan WANG Yong-Xin WANG Guan HU Hui-Zhong ZHOU Kai DUAN Ming-Xing ( Department of Biological sciences and Biotechnology, Tsinghua university, State Key Laboratory ofBiomembrane & Membrane Biotechnology, Beijing 100084,{2. college of Veterinary Medicine, Cornell university, NY 14853,USA 3. college of Life Science, hebei normal university, shijiazhuang 050016,{2.)

Summary Severe acute respiratory syndrome (SARS) is caused by SARS coronavirus(SARS-CoV),a novel infectious agent that brings a global pandemic. Research has shown that the genome of SARS-CoV is mutable and SARS may recur in the future. Four major structural proteins in the SARS-CoV are the spike, membrane, nucleocapsid, and small envelope proteins. It is imperative that a vaccine against SARS which would induce an intense protective immune response in the recipients be developed. Three eukaryotic expression plasmids were designed for this goal in our lab using vector pVAX1. S-1 segment (831bp, ranging from 37 to 867 base locus in the S gene), a truncated fragment of S gene encoding spike protein, was used to construct the target plasmids. In addition, different numbers of CpG motifs were introduced into the constructs via polymerase chain reaction (PCR) to improve the immune response. The expressed target proteins were readily detectable in 2.3T cells via western blot following transfection with the constructed plasmids. 6-8 week female BALB/c mice were primed and boosted with 50ug constructs at two week intervals by injecting into quadriceps femoris using electroporation (12.per group). Peripheral blood was collected from the tail vein of mice before and at selected times after immunization. And the clear supernatants of 10% (W/V) homogenates of spleens were prepared to explore the changes of cytokines. Results show that IgG1 and IgG2. increased significantly in the vaccinated mice (P2./IgG1. IFNγand IL-2.in the spleen increased 3-6 folds comparing to the control group, suggesting that they can induce an effective immune response. Our studies confirm the occurrence of switch from Th2.Th1 phenotype to Th1 immune response because of inserting CpG motifs into the constructs. DNA vaccination enhanced by CpG motifs may open up a new avenue for prophylaxis and treatment of SARS.

关键词： DNA Vauine SARS CpG motifs

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Evaluation of 10 plant barcodes in Bryophyta (Mosses)

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Journal of Systematics and Evolution 2010年第1期48卷 36-46页

作者： 1,2.Yan LIU 3 Hai-Fei YAN 4 Tong CAO 3 Xue-Jun GE 1(Institute of Applied Ecology, Chinese Academy of sciences, Shenyang 110016, china) 2.Graduate {2. of the Chinese Academy of sciences, Beijing 100049, china) 3(Key Laboratory of Plant resources Conservation and Sustainable Utilization, South china Botanical Garden, Chinese Academy of sciences, Guangzhou 510650, china) 4(college of Life & Environment sciences, Shanghai normal {2., Shanghai 2.02.4, china) (Institute of Applied Ecology Chinese Academy of Sciences Shenyang 110016 China) (Graduate university of the Chinese Academy of sciences Beijing 100049 China) (Key Laboratory of Plant resources Conservation and Sustainable Utilization South China Botanical Garden Chinese Academy of Sciences Guangzhou 510650 China) (college of Life & Environment sciences Shanghai Normal University Shanghai 200234 China) *Correspondence: Tong CAO Xue-Jun GE *Correspondence: *?Author for correspondence: E-mail: ct1946@*** xjge@*** Tel./Fax: 86-2.-372. 2.51.

DNA barcoding is a molecular tool that uses a standardized DNA region to identify *** preliminary study reported here is the first attempt to specifically focus on universality and attributes of candidate barcodes across a wide systematic range of *** tested eight previously proposed plant barcoding regions(atpF-atpH, ITS2. matK, psbK-psbI, rbcL, rpoB, rpoC1, and trnH-psbA) and two popular phylogenetic markers(rps4 and trnL-trnF of cpDNA) in 49 moss species and 9 liverwort species, representing half of the orders in moss *** ITS2. rbcL, rpoC1, rps4, trnH-psbA and trnL-trnF regions showed good universality, and therefore the efficacy of these loci as DNA barcodes was further evaluated in 36 mosses and 2.liverworts, each of which included two to three individuals per *** five loci, ***, rpoC1, rps4, trnH-psbA and trnL-trnF, were easy to amplify and sequence and showed significant inter-specific genetic variability, making them potentially useful DNA barcodes for *** best performing single loci were the rbcL and rpoC1 coding *** loci showed equivalent performance and combinations of them did not greatly increase their discrimination *** addition, phylogenies generated from each of the separate regions and multi-locus combinations by using best-fit and Kimura 2.parameter models were compared, but no significant difference was found.

关键词： Bryophyta DNA barcoding rbcL rpoC1 rps4 trnH-psbA trnL-trnF.

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三峡库区坡地资源优化利用模式与途径

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山地学报 2005年第2期23卷 197-202页

作者：廖和平邓旭升卢艳霞西南师范大学资源与环境科学学院中国科学院地理科学与资源研究所中国科学院地理科学与资源研究所重庆400715 北京100101

三峡库区土地资源以山丘地为主,耕地又以坡旱地为主。其中>2.5°的陡坡耕地为2.6 7×10 4hm2.,占库区耕地总量的18.2.%。研究表明,三峡库区粮食产量的5 6 %来自坡耕地,同时库区泥沙量的6 6 %也来自坡耕地。三峡大坝蓄水,移民后靠安置,... 详细信息

三峡库区土地资源以山丘地为主,耕地又以坡旱地为主。其中>2.5°的陡坡耕地为2.6 7×10 4hm2.,占库区耕地总量的18.2.%。研究表明,三峡库区粮食产量的5 6 %来自坡耕地,同时库区泥沙量的6 6 %也来自坡耕地。三峡大坝蓄水,移民后靠安置,对坡耕地利用的压力更大。坡地资源的优化利用,在库区农业生产、移民安置,以及生态环境建设方面都具有重要的意义和价值。基于土地资源优化利用原理和生态设计的理念,提出库区土地资源优化利用应突出生态效益、经济主导、产业协调、区域特色等4种模式,并针对当前库区土地资源利用中的主要问题,提出了相应的优化利用途径和对策

关键词：土地资源山坡耕地优化利用三峡库区

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Magnetostratigraphy of the late Cenozoic Laojunmiao anticline in the northern Qilian Mountains and its implications for the northern Tibetan Plateau uplift

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Science china Earth sciences 2005年第7期 1040-1051页

作者： FANG Xiaomin1,2. ZHAO Zhijun3,2. LI Jijun2. YAN Maodu2. PAN Baotian2. SONG Chunhui2.& DAI Shuang2. 1. Institute of Tibetan Plateau Research, Chinese Academy of sciences, Beijing 100085, china 2. Key Laboratory of Western china's environmental Systems, Ministry of Education & college of resources and Environment, Lanzhou university, Lanzhou 730000, china 3. college of Geography, Nanjing normal university, Nanjing 2.0097, china

Cenozoic sediments in the foreland basin——Jiuquan Basin in west Hexi Corridor recorded tectonic uplift information of the Qilian Mountains. High resolution paleomagnetic dating of the Laojunmiao （LJM） section across the central LJM anticline in the southern Jiuquan Basin reveals ages of the Getanggou Member, Niugetao Member in the Shulehe Formation, the Yumen Conglomerate, Jiuquan Conglomerate and Gobi Formation at >13―8.3 Ma, 8.3―4.9 Ma, 3.66― 0.93 Ma, 0.84―0.14 Ma and 0.14―0 Ma, respectively. Sedimentary evolution study suggests that the Qilian Mountains should begin to rise gradually since8―6.6 Ma, accompanied by sedimentary environments changing from lacustrine mudstones-sandstones to alluvial conglom- erates. Rapid uplift of the Qilian Mountains began at3.66 Ma, followed by a series of stepwise or intermittent intensive uplifts at about 2. Ma, 0.93―0.84 Ma and 0.14 Ma, which finally resulted in the present high Qilian Mountains.

关键词： Qilian Mountains Qinghai-Tibetan Plateau Jiuquan Basin magnetostratigraphy.

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Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2.up-regulation in macrophages

Dipyrithione inhibits lipopolysaccharide-induced iNOS and CO...

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“细胞活动生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会

作者： Yumei Fan~(a,1),Zhimin Yin~b a.The Key Lab of Animal Physiology,Biochemistry and Molecular Biology of hebei Province,college of Life Scicnce,hebei normal university,shijiazhuang 050016,PR china b.Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology,college of Life sciences, Nanjing normal university,Nanjing 2.0097,PR china

Dipynthione(PTS2. possesses anti-bacterial and anti-fungal *** the present study,we found that PTS2.dose-dependently inhibited the LPS-induced up-regulation of nitric oxide synthase(iNOS) and cyclooxygenase-2.COX-2. protein level in RAW2.4.7 ***-PCR experiments showed that PTS2.suppressed LPS-induced iNOS but not COX-2.expression at the mRNA *** expected,PTS2.prevented NO secretion in RAW2.4.7 ***,PTS2.administration significantly decreased LPS-induced mortality in ***-cally,PTS2.decreased expression and phosphorylation of STAT1,but did not interfere with the MAPK and NF-kB *** conclusion,PTS2.protects mice against endotoxic shock and inhibits LPS-induced production of pro-inflammatory mediators,suggesting that PTS2.could play an anti-inflammatory role in response to LPS.

关键词： Dipyrithione Lipopolysaccharide iNOS COX-2 STAT1

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Impacts of landscape fragmentation on breeding habitats of Oriental White Stork in the Sangjiang Plain,china

Impacts of landscape fragmentation on breeding habitats of O...

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第三世界生态高峰会

作者： Liu HongYu~1 Li Zhaofu~2.1.college of Geography,Nanjing normal {2..12.,Ninghai Road.Nanjing,china,2.0097 2.college of resources and environmental sciences,Nanjing Agricuitural {2..l,Weigang Road,Nanjing 2.0095,china

Since the fragmentation of natural habitat is one of the most serious problems for many species,it is highly interesting to study the impacts of landscape fragmentation on habitats of endangered *** Oriental White Stork,as a representative wetland waterfowls in the Sanjiang Plain,china,has sharply declined in population during the last decades apparently due to forest harvesting and fragmentation of natural wetland *** measures have led to the establishment of a wetland reserve to assure the persistence of Oriental White Stork at a regional ***,little is known about the effects of landscape structure on the distribution of Oriental White *** identified six key breeding habitat variables and tested them by field censuses during 2.04 ***,establishing a HSI model and integrated it into GIS to evaluate the breeding habitats of Oriental White Stork and their dynamic changes over the past *** show that the positive role of particular landscape features on stork distribution indicates that both the wetland landscape complex and the surrounding matrix of breeding habitats has an important role in determining the distribution of *** the habitats of Oriental White Storks was composed of complex landscape of wetland types,in which island-like forest swamps were as nesting area and marshes, lakes and ponds as food area for Oriental White Storks in the study area, so Breeding habitats located in complex wetland landscapes showed a higher quality habitat of storks than in a fragmented *** disturbance and reclamation of wetlands that resulted wetland fragmentation is the most important factors to impact quality of breeding habitat of storks in the Sanjiang Plain,Patch area of wetlands had more effects on habitats when landscape matrix was in lower fragmented state when wetland area accounted of more than 50% of the total study area and landscape connectivity was larger than 50;and isolation in la

关键词： wetland landscape fragmentation habitat Oriental White Storks

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Isotopic Stratification and Its Implications in Groundwater of Northern china

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Journal of Earth Science 2001年第3期 63-71页

作者： Chen Zongyu Institute of Hydrogeology and environmental Geology, Chinese Academy of Geological sciences, {2. 050061 college of Earth sciences, Jilin university, Changchun 13002.Zhang Guanghui Ni Zhenlong Qi Jixiang Nan Yunju Institute of Hy

The contents of D, 8O, 3H and 14C, distinctive in shallow and deep Quaternary aquifers beneath northern china, reflect differences in average paleoclimatic conditions between the Holocene and the last glacial period in Pleistocene. Groundwater in deep confined aquifer was recharged during the last glacial period. The depletions of δ(D) and δ(18O) of this water, 4×10-3-16×10-3 and 1×10-3-2.10-3 when compared with the shallow water recharged in Holocene, suggest that the annual mean temperature was lower in the last glacial period than that in the Holocene. The continental gradient of D and 18O found in old groundwater is essentially similar to that in Holocene, suggesting that the atmospheric circulation did not undergo substantial changes over northern china for the past 30 000 years in spite of the changes in the temperature. Groundwater isotopic stratification indicates three different recharge mechanisms and the influence of modern hydrological circulation, which are very important for the understanding of the continental hydrological circulation and the sustainable development of groundwater {2..

关键词： isotopes aquifers paleoclimate and paleohydrology recharge mechanism sustainable development northern china.

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Analysis of land use change and its driving force in the Longitudinal Range-Gorge Region

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Science Bulletin 2007年第S2期 10-20页

作者： LI ZhengHai~(1,4+) SONG GuoBao~(1,2. L HaiYan~3 BAO YaJing~1 GAO JiXi~4 WANG HaiMei~5 XU Tian~6 CHENG Yan~7 1 Institute of Bio-resources and Environment,college of Life Science,Dalian Nationalities {2.,Dalian 116600,china 2.college of resources Science & Technology,Baijing normal {2.,Baijing 100875,china 3 Institute of Agricultural resources and Regional Planning,Chinese Academy of Agricultural sciences,Baijing 100081,china 4 Innovation Base of Regional Ecology,Chinese Research Academy of {12. sciences,Beijing 100012.china s Inner Mongolia Municipality Observatory,Huhhot 010051,china 6 college of Life sciences,Inner Mongolia {2.,Huhhot 01002.,china 7 college of Ecological Environment,Inner Mongolia Agricultural {2.,Huhhot 010018,china

The research on land use degree,land use change rate as well as regional difference of various land use types in the southwest Longitudinal Range-Gorge Region(LRGR)has been carried out on the re- gional and county *** the view of social economy,we have also analyzed the driving mecha- nism of land use change and the corresponding spatial scopes of various driving forces in the research *** research result indlcetse that,on the regional scale,farmland,forest and grassland compose the main body of land use in the LRGR,and the structural change of land use shows that grassland declines sharply,farmland increases and forest keeps *** the county scale,the land use is characterized by that land use level is relatively low,and the land use degree,the comprehensive variation rate and the relative variation rate among different land use types still *** analysis,the land use changes in the LRGR are mainly driven by investment Intensity of manpower and physical resources,the social economic output level,the intensity of natural disasters disturbance and educa- tional level of ***,the regionalism exists in the influence scope of different driving force types.

关键词： land use land use degree land use change rate driving force Longitudinal Range-Gorge Region(LRGR)

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土壤磷素分级方法研究评述

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土壤通报 2003年第3期34卷 229-232页

作者：胡佩周顺桂刘德辉四川师范大学化学与生命科学学院四川成都61066 南京农业大学资源与环境科学学院江苏南京210095

讨论了土壤磷素形态和有机磷有效性研究进展,分析了传统土壤磷素分级方法局限性,综述了土壤磷素分级方法的研究进展,特别详细地描述了Hedley法和Guppy法。

关键词：土壤磷素分级方法 Hedley法 Guppy法

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