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First complete genomic sequence analysis of canine distemper virus in wild boar

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Virologica Sinica 2024年第4期39卷 702-704页

作者： Tong Wang Haiying Du Na Feng Yuhang Liu Yu Xu Heting Sun Peng Peng Siyuan Qin Xiaotian Zhang Yan Liu Mingyuan Yu Hongrui Liang Biao He Guoqiang Zhu changchun Tu Zhongzhong Tu Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses Yangzhou UniversityYangzhou 225009China changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun 130122China Biological Disaster Control and Prevention Center National Forestry and Grassland AdministrationShenyang 110034China

Dear Editor,Canine distemper virus(CDV)is the causal agent of a highly contagious viral infectious disease that affects domestic and wild carnivores *** is an enveloped,non-segmented negative sense RNA virus that belongs to the Morbillivirus genus in Paramyxoviridae family,which contains viruses of epidemiological relevance to humans and *** on the variability of the hemagglutinin gene(H),CDV strains have been at least 2. major genetic lineages:America-1 to America-5,Canada-1 and-2.Asia-1 to Asia-6,Europe wild-life,Arctic,Africa-1/South Africa,Africa-2.South America-1 to South America-3 and Rockborn-like(Giacinti et al.,2.2.).Mutations in the binding sites of the H protein,which interact with viral entry receptors such as signaling lymphocytic activation molecule(SLAM)and nectin-4,are associated with the emergence of the disease in new host species(Beineke et al.,2.15).

关键词： distemper Canada globally

Simulating the Folding Pathway of RNA Secondary Structure Using the Modified Ant Colony Algorithm

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Journal of Bionic Engineering 2010年第4期7卷 382-389页

作者： Jun Yu~(1,2.,Changhai Zhang~(1,2.,Yuanning Liu~(1,2.,Xin Li~(1,2. 1.College of Computer science and technology,Jilin {2.,changchun 130012.P.R.china 2.Key Laboratory of Symbolic Computation and Knowledge Engineering (Ministry of Education,china) Jilin {2.,changchun 130012.P.R.china [a] College of Computer science technology Jilin University Changchun 130012 P. R. China [b] Key Laboratory of Symbolic Computation Knowledge Engineering (Ministry of Education China) Jilin University Changchun 130012 P. R. China

A new method for simulating the folding pathway of RNA secondary structure using the modified ant colony algorithmis *** a given RNA sequence,the set of all possible stems is obtained and the energy of each stem iscalculated and stored at the initial ***,a more realistic formula is used to compute the energy ofmulti-branch loop in the following *** a folding pathway is simulated,including such processes as constructionof the heuristic information,the rule of initializing the pheromone,the mechanism of choosing the initial andnext stem and the strategy of updating the pheromone between two different *** by testing RNA sequences withknown secondary structures from the public databases,we analyze the experimental data to select appropriate values *** measure indexes show that our procedure is more consistent with phylogenetically proven structures thansoftware RNAstructure sometimes and more effective than the standard Genetic Algorithm.

关键词： RNA secondary structure folding pathway ant colony algorithm

Genesis of continental seismogenic zone and a new fault zone model

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Chinese science Bulletin 2000年第20期45卷 1886-1892页

作者： LIU Junlai & M. Shimada1. Department of Earth sciences, changchun {2. of science and technology, changchun 13.02., china 2. RCEP, Disaster Prevention Research Institute, Kyoto {2., Uji, Kyoto, 611-0011, Japan Correspondence should be addressed to Liu Junlai i Department of Earth sciences Changchun University of Science and Technology Changchun China RCEP Disaster Prevention Research Institute Kyoto University Uji Kyoto Japan

Experiments were conducted repeatedly on Mannari granite under different temperature and confining pressure conditions. Systematic micro- and submicro-structural and mechanical analyses of granite samples deformed under 1.5 GPa (confining pressure), at 2. ℃-650 ℃ temperatures and at 2.10-6s-1 strain rate show the brittle-ductile deformation microstructures and microstructural associations similar to those observed in naturally deformed crustal rocks and minerals. Brittle fracturing and crystalline plasticity co-exist and react with each other in the brittle-ductile transition domain of the continental lithosphere. The interaction between the different mechanisms in the transitional domain results in the variation of anomalous strength values, which may best explain the genesis of the continental seismogenic zone. A new fault zone model is proposed on the basis of detailed micromechanical and microstructural analyses.

关键词： granite experimental rock deformation continental seismogenic zone fault zone model.

Prediction of collapse process and tipping points for mutualistic and competitive networks with k-core method

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Chinese Physics B 2024年第5期33卷 173-180页

作者：段东立毕菲菲李思凡吴成星吕长春蔡志强 School of Information and Control Engineering Xi'an University of Architecture and TechnologyXi'an 710311China School of Mechanical Engineering Northwestern Polytechnical UniversityXi'an 710072China

Ecosystems generally have the self-adapting ability to resist various external pressures or disturbances,which is always called ***,once the external disturbances exceed the tipping points of the system resilience,the consequences would be catastrophic,and eventually lead the ecosystem to complete *** capture the collapse process of ecosystems represented by plant-pollinator networks with the k-core nested structural method,and find that a sufficiently weak interaction strength or a sufficiently large competition weight can cause the structure of the ecosystem to collapse from its smallest k-core towards its largest *** we give the tipping points of structure and dynamic collapse of the entire system from the one-dimensional dynamic function of the *** work provides an intuitive and precise description of the dynamic process of ecosystem collapse under multiple interactions,and provides theoretical insights into further avoiding the occurrence of ecosystem collapse.

关键词： complex networks tipping points dimension reduction k-core

PDMS prism-glass optical coupling for surface plasmon resonance sensors based on MEMS technology

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science china(Information sciences) 2010年第10期53卷 2144-2158页

作者： GENG ZhaoXin 1,2., LI Qing 3 , WANG Wei 1 & LI ZhiHong 1 1 Institute of Microelectronics, Peking university, Beijing 100871, china 2.School of Information engineering, Minzu university of china, Beijing 100081, china 3 School of sciences, changchun university of science and technology, changchun 130000, china 1. Institute of Microelectronics Peking University Beijing 100871 China2. School of Information engineering Minzu University of China Beijing 100081 China3. School of Sciences Changchun University of Science and Technology Changchun 130000 China

A miniaturized surface plasmon resonance (SPR) chip has been developed for biomedical and chem-ical analysis with low cost and high performance. The techniques of bulk silicon micromachining and polymer replication were used to fabricate the Kretschmann SPR sensor composed of a Polydimethylsiloxane (PDMS) prism, a coupling glass and microchannels. The plasmon properties of thin metal films were investigated theoret-ically based on Fresnel analysis, with optical boundary conditions pertaining to the surface plasmon resonance at the gold/water and gold/air interfaces. The theoretical results show that difference in the refractive index (RI) between the PDMS prism and the coupling glass layer affect the precision of the SPR angle and the SPR curve. Meanwhile, the period of the interference fringe attaching on the SPR curve increases with an increase in wavelength and a decrease in the refractive index of the coupling glass layer. The gold thickness of 50 nm is required while employing a fixed incident wavelength of 650 nm, to achieve optimum SPR excitation conditions and the sensor sensitivity. The characteristics of this SPR sensor were evaluated in the angular interrogation mode of employing the incident wavelength of 650 nm in air and water media, respectively. The obtained SPR angles were approximately consistent with the theoretical ones.

关键词： surface plasmon resolance polymer microfluidic PDMS

Study on the Mode Losses and Bending Lossesof Hollow-core Optical Fiber of GeO2.andSiO2.Bases for Transmitting CO2.Laser Energy

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Chinese Journal of Lasers 1996年第1期B5卷 27-32页

作者： HOU Lantian (Department of Physics,Jilin university,changchun {2. china)SUN Yingzhi (Light Communication Department,changchun Poat and Telecommunication Institte,changchun 130012.china)ZHAO Bin(Department of Physics,science and technology university of Jilin Univ Changchun China

The transmitting losses of several lower modes for four kinds of straight and bent circular hollow optical fibers （waveguide） made up with GeO2.or SiO2.and doped with PbO or Sb2.3 respectively are calculated. The results show that the HE11 mode has the minimum loss in straight waveguide and the loss of TM01 mode in bent waveguide is the minimun.

关键词： hollow-core optical fiber low-order mode bending loss

Edaphic factors determining variation of two ecotypes of Leymus chinensis in North china

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Progress in Natural science:Materials International 2006年第11期16卷 1150-1155页

作者： ZHOU Chan~1 and YANG Yunfei~2.*(1. MOE Key Laboratory of Environmental Change and Natural Disasters, College of Resources science and technology, Beijing Normal {2., Beijing 100875, china 2. Key Laboratory of Vegetation Ecology, Ministry of Education, Institute of Grassland science, Northeast Normal {2., changchun 13.02., china) [a]MOE Key Laboratory of Environmental Change and Natural Disasters College of Resources Science and Technology Beijing Normal University Beijing China [b]Key Laboratory of Vegetation Ecology Ministry of Education Institute of Grassland Science Northeast Normal University Changchun China

To identify ecotypic variation of L. chinensis, the physiological characteristics and environmental factors were measured and assessed for grey-green and yellow-green ecotypes of L. chinensis grown in the salt-alkalized and aeolian sandy soils. Although both ecotypes presented a similar salt-alkaline tolerance under the experimental conditions, they differed in several aspects. The L. chinensis grown in the aeolian sandy soils had higher water potential and chlorophyll content and lower proline content in their leaves than those grown in the salt-alkalized habitat, and the grey-green ecotype of L. chinensis in both types of soils had higher water potential, chlorophyll and proline contents than the yellow-green ecotype. Besides, grey-green ecotypes had higher salt-alkaline tolerance than the yellow-green ecotype. The stepwise regression analysis showed that soil conductance and pH value were the main ecological factors affecting the physiology of L. chinensis. From the natural distribution of the two ecotypes, we considered that salt-alkaline in the soils is the leading factor in determining ecotypic variation of L. chinensis. The two ecotypes were first named grey-green and yellow-green ecotypes respectively.

关键词： L.chinensis ecotype adaptability variation ecological factor salt-alkaline in soil.

Inulin alleviates HFD-induced NAFLD by hepatic macrophage polarization and lipid metabolism via gut-liver axis

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Food science and Human Wellness 2024年

作者： Wei Song Jinhong Hu Lina Zhu Bing Chen Lingling Li Xiaole Cui Ting Zhang Yaxing Miao Kaixin Su changchun Liu Yane Luo Tianli Yue College of Food science and technology， Laboratory of Nutritional and Healthy Food-Individuation Manufacturing Engineering， Research Center of Food Safety Risk Assessment and Control， Northwest {2.

Long-term intake of high-fat diet (HFD) leads to systemic hypo-inflammation， which is involved in the pathogenesis of many liver diseases. The aim of this study was to evaluate the interventional effect of inulin addition on HFD-induced non-alcoholic fatty liver disease (NAFLD). Here， we assessed liver inflammation and lipid metabolism by ELISA kits and real-time quantitative polymerase chain reaction (qPCR)， and explored its relationship with intestinal flora and metabolites by 16S rDNA gene sequencing and untargeted metabolomics. In addition， we determined the effect of the inositol-requiring enzyme-1α (IRE1α-XBP1) pathway on liver macrophage polarization by flow cytometry. In conclusion， our study has demonstrated that inulin ameliorates high levels of bile acids and colonic immune disorders induced by HFD， and improves hepatic macrophage polarization and hepatic lipid metabolism via the intestine-hepatic axis， thus providing a mechanistic basis for therapeutic approaches to modulate bile acids to improve colonic inflammation and nonalcoholic fatty liver disease.

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Synthesis,characterization,properties and crystal structure of heterometallic 1D coordination polymers {[CuLZn·CuLZn(H_2.)]·H_2.}_n

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science china Chemistry 2006年第4期49卷 338-344页

作者： TAO Ruojie1, LI Fu’an1, ZANG Shuangquan1, CHENG Yanxiang2.& NIU Jingyang1 1. Chemistry and Chemical Engineering College of Henan university, Kaifeng 475001, china 2. {2. Institute of Applied Chemistry, Chinese Academy of sciences, changchun 13.02., china 1. Chemistry and Chemical Engineering College of Henan university Kaifeng 475001 China 2. changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China

Copper-zinc heterometallic 1D chain coordination polymer has been synthesized and characterized by elemental analysis, and IR spectra etc. The crystal structure was determined by single-crystal X-ray diffraction analyses. The title complex is 1D chain coordination polymer with the chemical formula {[CuLZn·CuLZn(H2.)]·H2.}n, where H4L=N-(2.hydroxybenzamido)-N’-(3-carboxy- lsalicylidene)ethylenediamine. Its structural unit is comprosed of two tetranuclear cycles formed by two dissymmetrical tetranuclear units. These units polymerized each other to form 1D chain coordi- nation polymer.

关键词： copper, zinc, heterometallic coordination polymer, crystal structure.