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Cell Research 2006年第4期16卷 356-366页

作者： Xiao Xia Wang~(1,2. Rong Liu~1 Shun Qian Jin~1 Fei Yue Fan~2.Qi Min Zhan~1 ~1State Key Laboratory of Molecular Oncology,Cancer Institute,chinese {3. of Medical {2. and Peking Union Medical College,beijing 10002.,china ~2.nstitute of Radiation Medicine,chinese {3. of Medical {2. and Peking Union Medical College,Tianjin 3.0192.china 2.nstitute of Radiation Medicine Chinese Academy of Medical Sciences and Peking Union

Aurora-A kinase,a serine/threonine protein kinase,is a potential *** and overexpression of Au-rora-A have been found in several types of human tumors,including esophageal squamous cell carcinoma(ESCC).It hasbeen demonstrated that cells overexpressing Aurora-A are more resistant to cisplatin-induced ***,themolecular mechanisms mediating these effects remain largely *** this report,we showed that overexpressionof Aurora-A through stable transfection of pEGFP-Aurora-A in human ESCC KYSE150 cells significantly promotedcell proliferation and inhibited cisplatin- or UV irradiation-induced *** of caspase-3.and poly(ADP-ribose)polymerase(PARP)in Aurora-A overexpressing cells were substantially reduced after cisplatin or UV ***,we found that silencing of endogenous Aurora-A kinase with siRNA substantially enhanced sensitivityto cisplatin- or UV-induced apoptosis in human ESCC EC9706 *** parallel,overexpression of Aurora-A potentlyupregulated the expression of ***,the knockdown of Bc1-2.by siRNA abrogated the Aurora-A's effect oninhibiting *** together,these data provide evidence that Aurora-A overexpression promoting cell proliferationand inhibiting apoptosis,suggesting a novel mechanism that is closely related to malignant phenotype and anti-cancerdrugs resistance of ESCC cells.

关键词： Aurora-A apoptosis caspase-3 PARP esophageal squamous cell carcinoma (ESCC) siRNA

Study of rapid transient explosive boiling under short-pulsed laser heating

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Progress in Natural Science:Materials International 2004年第8期 52-56页

作者： JIN Renxi 1,2. , HUAI Xiulan 1* and LIU Dengying 1(1. Institute of Engineering Thermophysics, chinese academy of {2., beijing 100080, china 2. Naval Submarine academy, Nuclear Power Teaching Unit, Qingdao 2.6071, china) Institute of Engineering Thermophysics，chinese academy of {2.，{3. 100080，china Naval Submarine academy，Nuclear Power Teaching Unit，Qingdao 2.6071，china Institute of Engineering Thermophysics，chinese academy of {2.，{3. 100080，china

Using acetone, ethanol, water and acetone-water mixture as test liquids, the rapid transient explosive boiling (RTEB) taking place under short-pulsed laser heating is observed in experiment. The behaviors of temperature variation are investigated via transient temperature measurement. The vapor bubble behaviors of RTEB are captured by high-speed photography, and the difference between RTEB and normal boiling is analyzed. The boiling heat transfer of RTEB is also discussed. It shows that the character of RTEB is far different from normal boiling.

关键词： explosive boiling short-pulsed laser transient measurement high-speed photography.

New Flavonoid Glycoside from Thalictrum przewalskii

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chinese Chemical Letters 1999年第4期10卷 295-296页

作者： Shi Chun YU Qing Li WU Li Wei WANG Pei Gen XIAO(Institute of Medicinal Plant Development, chinese academy of Medical {2. and Peking Union Medical College, {3. 100094.) chinese Acad Med Sci Inst Med Plant Dev Beijing 100094 Peoples R China Peking Union Med Coll Beijing 100094 Peoples R China

A new flavonoid glycoside, 5, 7-dihydroxy-4'-methoxyflavonoid 7-Q-[6-O-(4-O-acetyl-alpha-L-rhamnosyl)-3.O-beta-D-glucosyl]-6-O-acetyl-beta-D-glucoside was isolated from Thalictrum przewalskii. Its structure was determ... 详细信息

关键词： Thalictrum Thalictrum przewalskii flavonoid glycoside 5, 7-dihydroxy-4 '-methoxyflavonoid 7-O-[6-O-(4-O-acetyl-alpha-L-rhamnosyl)-3.O-beta-D-glucosyl]-6-O-acetyl-beta-D-glucoside

3.D Finite-Element Numerical Simulation of Centrifugal Induction Electrosalg Casting Solidification Process

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Journal of University of Science and Technology beijing 2001年第4期8卷 254-258页

作者： Xichun Chen, Deguang Zhou, Jie Fu, Weiguo Xu Metallurgy school, University of Science and Technology beijing beijing 100083.{3. Univ Sci & Technol beijing Met Sch Beijing 100083 Peoples R China

A 3.D finite-element numerical simulation model of temperature field for CIESC casting solidification process was developed with the aid of ANSYS software and a series of corresponding experiments were made. The results showed that the good agreement was obtained between the numerical simulation and the experiments. Based on the numerical simulation results, the characteristics of temperature distribution in the castings during CIESC solidification process were analyzed and summarized. According to the G/R-1/2.method and numerical simulation results, there is no any shrinkage defect in the CIESC casting and structure or casting is fine and compact.

关键词： 3.D finite-element numerical simulation ANSYS software solidification process centrifugal induction electroslag casting (CIESC) shrinkage defect

简单芳香化合物的结构和性质对活性炭吸附行为的影响

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燃料化学学报 2010年第2期38卷 252-256页

作者：李秉正刘振宇雷智平黄张根中国科学院山西煤炭化学研究所煤转化国家重点实验室山西太原030001 中国科学院研究生院北京100049 北京化工大学化工资源有效利用国家重点实验室北京100029

用静态吸附法考察了一种活性炭对废水中四种简单芳香化合物的吸附行为,并用Langmuir模型对吸附数据进行了拟合。结果表明,Langmuir模型可以近似地描述这些芳香化合物在该活性炭上的吸附行为。芳香化合物的极性及其在水中的溶解度对其在... 详细信息

用静态吸附法考察了一种活性炭对废水中四种简单芳香化合物的吸附行为,并用Langmuir模型对吸附数据进行了拟合。结果表明,Langmuir模型可以近似地描述这些芳香化合物在该活性炭上的吸附行为。芳香化合物的极性及其在水中的溶解度对其在活性炭上吸附的影响较大,芳香化合物与活性炭之间的π-π色散作用对吸附的影响很小。

关键词：活性炭芳香化合物吸附 π-π色散作用溶解度极性

A new space-time interference suppression method for GNSS receiver

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A new space-time interference suppression method for GNSS re...

Impaired long-term plasticity in the mice lacking xCT,a subunit of cystine/glutamate transporter

第三届中国卫星导航学术年会

作者： Guo Yi 1,2., Fan Ming 3.1. beijing Global Information Center ,beijing,{2., 100094 2. school of Automation Science and Electrical Engineering of beijing University of Aeronautics and Astronautics, beijing,{2., 100094 3. school of Mechanical Engineering and Automation of beijing University of Aeronautics and Astronautics, beijing,{2., 100094

Space-time interference suppression technique shows great predominance compared with other anti-jamming techniques. LCMV（Linearly Constrained Minimum Variance） criterion is often used in space-time adaptive processing. Beaming steering and null steering methods were deeply analyzed on LCMV criterion. A new space-time anti-jamming method is proposed combining beam steering and null steering. The method reduces the signal loss of satellite signal DOA estimation error compared with beaming steering and improves the output SINR compared with null steering. Numerical simulation demonstrates that the proposed method is effective and efficient.

关键词： space-time interference suppression beam steering null steering

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Impaired long-term plasticity in the mice lacking xCT,a subu...

Problems for water resources development in typical small karst drainage basins and countermeasures

The 2.d International and 11th National Symposium on Membrane Biology

作者： Yan Li~(1,2.,Wei Li~1 1.Key Laboratory of Molecular and Developmental Biology,Institute of Genetics and Developmental Biology,chinese academy of {2.,beijing,china 2.Graduate University of chinese academy of {2.,beijing,china

xCT is the functional subunit of amino acid transporting system X which exchanges extracellular cystine with intracellular *** has been demonstrated to play an important role in redox maintenance,mostly in vitro or under pathological *** we use sut mouse,an xCT null mutant,to explore the function of xCT under physiological

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Journal of Geographical sciences 2000年第2期10卷 168-176页

作者： WAN Hong-tao, XIE Chuan-jie, SHI Yun-liang (LREIS, Institute of Geographical sciences and Natural Resources, chinese {2. of sciences, beijing 100101, china, Department of Urban and Resource, Nanjing University Nanjing 2.0093. china) 中科院地理与资源所资源与环境信息系统国家重点实验室北京南京大学江苏南京

In karst area water deficit is one of the main factors constraining sustainable economic development. In 1979 the comprehensive karstic observational field station was set up in Houzhai drainage basin located,\ in Puding county of Guizhou Province, which can represent most of the small karst drainage basins on the dividing line of the Guizhou Plateau. Geomorphology, water resources and water chemistry were investigated and observed. Based on comparisons of water supply with water demand and analysis of the main problems in water exploitation and utilization. it is found out that the water deficiency was not directly caused by the scarcity of natural water resources. The true reason is the insufficient capacity of water supply caused by the dismatch of the water and soil water resources which can be dealt with by building more irrigation works. Some solutions such as to build scientific basis for water exploitation and utilization and sustainable economic development in karst drainage basins on dividing line of the Guizhou Plateau.

关键词： small karst drainage basin water resources comparison of water supply and demand sustainable exploitation and utilization

Surface Molecular Nanopatterns:Structure and Property

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Surface Molecular Nanopatterns:Structure and Property

一种求解不可压粘性流动的高阶精度迎风格式的应用

全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会

作者： Lijun Wan~* (Institute of Chemistry,chinese academy of {2.,{3. 100080,china) Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China

Organic molecules with different functions could be employed to fabric ate molecular *** important issue in the application of functional molecule for molecular device is the precise control of nanostructure and arrangement of molecules on solid *** this presentation, we report the recent results on surface molecular nanopattem

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水动力学研究与进展（A辑） 2002年第2期17卷 245-252页

作者：马晖扬中国科学院研究生院北京100039

本文应用人工可压缩性方法和高阶迎风差分格式相结合的方法 ,进行不可压缩粘性流动的数值计算 ,通过对典型算例的研究 ,表明高阶格式可以在网格较少的情形下获得较高的精度。

关键词：不可压缩粘性流动人工可压缩性高阶格式网格收敛性计算流体力学