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Sex differences in the scored Patient-Generated Subjective Global Assessment in 19,528 cancer patients

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Journal of Nutritional Oncology 2023年第1期8卷 38-46页

作者： Wang Yan-Li Wu Tian-Tian Fu Zhen-Ming Guo Zeng-Qing Lin Yuan Shi Ying-Ying Hu Wen Ba Yi Li Su-Yi Li Zeng-Ning Wang Kun-Hua Wu Jing He Ying Yang Jia-Jun Xie Cong-Hua Zhou Fu-Xiang Song Xin-Xia Chen Gong-Yan Ma Wen-Jun Luo Su-Xia Chen Zi-Hua Cong Ming-Hua Ma Hu Zhou Chun-Ling Wang Wei Luo Qi Shi Yong-Mei Qi Yu-Mei Jiang Hai-Ping Guan Wen-Xian Chen Jun-Qiang Chen Jia-Xin Fang Yu Zhou Lan Feng Yong-Dong Tan Rong-Shao Li Tao Ou Jun-Wen Zhao Qing-Chuan Wu Jian-Xiong Lin Xin Yang Liu-Qing Zhang Qi Jia Ping-Ping Li Wei Xu Hong-Xia Shi Han-Ping Song Chun-Hua The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group chinese Society of Nutritional Oncology Department of Epidemiology and Statistics College of Public HealthZhengzhou UniversityZhengzhouHenanChina Cancer Center Renmin Hospital of Wuhan UniversityWuhanHubeiChina Department of Medical Oncology Fujian Cancer HospitalFujian Medical University Cancer HospitalFuzhouFujianChina Department of Gastrointestinal Surgery Affiliated Tumor Hospital of Guangxi Medical UniversityNanningGuangxiChina Department of Surgery The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongChina Department of Clinical Nutrition West China Hospital of Sichuan UniversityChengduSichuanChina Department of Gastrointestinal Oncology Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin Key Laboratory of Cancer Prevention and TherapyTianjinChina Department of Nutrition and Metabolism of Oncology Affiliated Provincial Hospital of Anhui Medical UniversityHefeiAnhuiChina Department of Clinical Nutrition The First Hospital of Hebei Medical UniversityShijiazhuangHebeiChina Department of Gastrointestinal Surgery Institute of GastroenterologyThe First Affiliated Hospital of Kunming Medical UniversityKunmingYunnanChina Zhongshan Chenxinghai Hospital(Affiliated Zhongshan Chenxinghai Hospital of Guangdong Medical University) ZhongshanGuangdongChina Department of Clinical Nutrition The First People's Hospital of KashiKashiXinjiangChina Department of Clinical Nutrition Chongqing General HospitalChongqingChina Department of Colorectal and Anal Surgery Huizhou Municipal Central HospitalHuizhouGuangdongChina Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhanHubeiChina Department of Oncology Xingtai People’s HospitalHebei Medical UniversityXingtaiHebeiChina The First Department of the Tumor Hospital of Harbin Medical University HarbinHeilongjiangChina Department of Nutrition Guangdong General HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdongChina Department of Oncology Affiliated

Background:The scored Patient-Generated Subjective Global Assessment(PG-SGA)has been widely used to assess the nutritional status of cancer *** purpose of this study is to compare the differences in PG-SGA scores and the 7 domain scores of the PG-SGA in male and female cancer ***:This study was conducted at 72 hospitals from July 2013 to December 2018,a part of the Investigation on Nutritional Status and its Clinical Outcomes of Common *** PG-SGA was recorded to evaluate the nutritional status of patients.A total of 19,528 patients with 13 common malignancies were included in this *** t test and the χ^(2) test were applied to analyze the sex diferences in the 7 domain *** Cancer Genome Atlas(TCGA)database was used to analyze the expression levels of symptom-related ***:There were significant sex dfferences in the PG-SGA(P=0.032),notably in patients with gastric cancer(male vs female:9.09±4.86 vs 9.58±5.07,P=0.005)and esophageal cancer(9.64±4.90 vs 10.46±4.96,P=0.011)and the average total PG-SGA of female patients was slightly higher than that of male patients(7.64±4.98 vs 7.77±5.14).The differences were mainly related to the weight,eating,symptom,as well as activity and physical function scores in the stratified *** causes of the sex differences were the rates of nausea,vomiting,dry mouth,and other symptoms,in both gastric and esophageal cancer *** of the TCGA database suggested that most of the related genes were sex neutral,except for genes related to dysphagia in gastric cancer(VEGFC was higher in female patients,VEGFA and VEGFB higher in male patients).Conclusions:There are sex differences in the PG-SGA scores in patients with various tumor types(female patients generally had higher scores than male patients),with differences mainly in the weight,eating,symptom,as well as activity and physical function *** sex differences in PG-SGA scores might be due to the differences i

关键词： PG-SGA Sex differences Malnutrition Cancer patients TCGA database

AI智能动态心电记录设备在运动性心脏猝死三级防治体中的应用

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河北北方学院学报（自然科学版） 2021年第12期37卷 24-27页

作者：赵晓敏张爱爱张鹏祥李飞星王晓元宋国振陶冬李方江河北北方学院研究生院河北张家口075000 河北北方学院附属第一医院河北张家口075000 上海乐普云智科技股份有限公司上海201600

通过研发改进目前心电监护设备,应用AI心电分析软件,提高运动性心脏猝死早期检出率和救治成功率,完善运动性心脏猝死的三级防治体系建设。通过反复学习、培训、演练、实践,发现问题、制定计划、解决问题,达到心电判读、预警联络、医疗... 详细信息

通过研发改进目前心电监护设备,应用AI心电分析软件,提高运动性心脏猝死早期检出率和救治成功率,完善运动性心脏猝死的三级防治体系建设。通过反复学习、培训、演练、实践,发现问题、制定计划、解决问题,达到心电判读、预警联络、医疗救治无缝衔接,形成标准化流程,可实现AI智能动态心电记录设备优势。

关键词： AI智能动态心电设备运动性心脏猝死防治体系

CACA Guidelines for Holistic Integrative Management of Breast Cancer

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Holistic Integrative Oncology 2022年第1期1卷 76-126页

作者： Jiong Wu Daiming Fan Zhimin Shao Binghe Xu Guosheng Ren Zefei Jiang Yongsheng Wang Feng Jin Jin Zhang Qingyuan Zhang Fei Ma Jinli Ma Zhonghua Wang Shusen Wang Xiaojia Wang Shu Wang Haibo Wang Tao Wang Xiang Wang Jing Wang Jia Wang Biyun Wang Li Fu Hongyuan Li Yehui Shi Lu Gan Yunjiang Liu Jian Liu Zhenzhen Liu Qiang Liu Qiang Sun Wenwu Cheng Keda Yu Zhongsheng Tong Xinhong Wu Chuangui Song Jianguo Zhang Jian Zhang Junjie Li Bin Li Man Li Huiping Li Wentao Yang Hongjian Yang Benlong Yang Hong Bu Juping Shen Zhenzhou Shen Yiding Chen Ceshi Chen Da Pang Zhimin Fan Ying Zheng Xiaoli Yu Guangyu Liu Xichun Hu Yiqun Ling Jinhai Tang Yongmei Yin Cuizhi Geng Peng Yuan Yajia Gu Cai Chang Xuchen Cao Yuan Sheng Yuanxi Huang Jian Huang Weijun Peng Xiaohua Zeng Yuntao Xie Ning Liao Committee of Breast Cancer Society,chinese Anti-Cancer Association Key Laboratory of Breast Cancer in shanghai Department of Breast SurgeryFudan University Shanghai Cancer CenterShanghai Medical College of Fudan UniversityShanghaiChina Department of Oncology Shanghai Medical College of Fudan UniversityShanghaiChina Department of Gastroenterology Beijing Chaoyang HospitalCapital Medical UniversityBeijingChina State key Laboratory of Cancer Biology National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive DiseasesFourth Military Medical UniversityXi’anChina National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Endocrine and Breast Surgery The First Affliated Hospital of Chongqing Medical UniversityYuzhongChongqingChina Medicine-Oncology The Affliated Hospital of Military Medical Sciences(The 307th Hospital of Chinese People’s Liberation Army)BeijingChina Breast Disease Center Shandong Cancer HospitalJinanChina Department of Breast Surgery The First Affliated Hospital of China Medical UniversityShenyangChina The 3rd Department of Breast Cancer China Tianjin Breast Cancer PreventionTreatment and Research CenterTianjin Medical University Cancer Institute and HospitalNational Clinical Research Center of CancerTianjinChina Harbin Medical University Cancer Hospital HarbinChina Department of Radiation Oncology Fudan University Shanghai Cancer CenterShanghai Medical College of Fudan UniversityShanghaiChina Sun Yat-Sen University Cancer Center GuangzhouChina Zhejiang Cancer Hospital HangzhouChina Breast Center Peking University People’s HospitalBeijingChina Department of Breast Center The Affliated Hospital of Qingdao UniversityShandongChina Department of Oncology Fifth Medical Center of Chinese PLA General HospitalBeijingChina Department of Breast Surgical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Departmen

Purpose:Breast cancer is now the most common malignant tumor *** one-fourth of female cancer patients all over the world sufer from breast *** about one in six female cancer deaths worldwide is caused by breast *** terms of absolute numbers of cases and deaths,china ranks frst in the *** CACA Guidelines for Holistic Integrative Management of Breast Cancer were edited to help improve the diagnosis and comprehensive treatment in ***:The Grading of Recommendations Assessment,Development and Evaluation(GRADE)was used to classify evidence and ***:The CACA Guidelines for Holistic Integrative Management of Breast Cancer include the epidemiology of breast cancer,breast cancer screening,breast cancer diagnosis,early breast cancer treatment,advanced breast cancer treatment,follow-up,rehabilitation,and traditional chinese medicine treatment of breast cancer ***:We to standardize the diagnosis and treatment of breast cancer in china through the formulation of the CACA Guidelines.

关键词： Epidemiology of breast cancer Breast cancer screening Breast cancer diagnosis Early breast cancer treatment Advanced breast cancer treatment Traditional chinese medicine treatment of breast cancer

定制式3D打印骨盆肿瘤假体设计与临床应用专家共识

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中华骨与关节外科杂志 2022年第7期15卷 491-500页

作者：中国抗癌协会肉瘤专业委员会骨盆肿瘤学组中国抗癌协会肉瘤专业委员会创新与转化学组中国抗癌协会骨肿瘤和骨转移瘤专业委员会修复重建学组闵理孙伟杨毅李浩淼李小康于胜吉张清屠重棋郭卫蔡郑东蔡建强董扬胡永成李建民林建华牛晓辉曲国蕃沈靖南邵增务王国文叶招明张伟滨郭征不详四川大学华西医院骨科骨科研究所成都610041 上海交通大学附属第一人民医院骨科上海200080 北京大学人民医院骨肿瘤科北京100044 南方医科大学第三附属医院骨科广州510630 空军军医大学唐都医院骨科西安710038 中国医学科学院肿瘤医院骨科北京100021 北京积水潭医院骨肿瘤科北京100035 中国医学科学院肿瘤医院肝胆外科北京100021 上海市第六人民医院骨科上海200233 天津医院骨肿瘤科天津300210 山东大学齐鲁医院骨科济南250012 福建医科大学附属第一医院骨科福州361003 哈尔滨医科大学附属肿瘤医院骨科哈尔滨150081 中山大学附属第一医院骨肿瘤科广州510080 华中科技大学同济医学院附属协和医院骨科武汉430022 天津医科大学肿瘤医院骨与软组织肿瘤科天津300060 浙江大学医学院附属第二医院骨科杭州310009 上海交通大学医学院附属瑞金医院骨科上海200025

功能性重建骨盆肿瘤切除后残留的巨大骨缺损是骨肿瘤外科医师必须面对的巨大挑战。骨盆假体因具有较好的初始稳定性、外形更易被接受、以及功能恢复相对较快等特点,近年来逐渐成为骨盆恶性或侵袭性肿瘤切除后的主要重建手段。但传统骨... 详细信息

功能性重建骨盆肿瘤切除后残留的巨大骨缺损是骨肿瘤外科医师必须面对的巨大挑战。骨盆假体因具有较好的初始稳定性、外形更易被接受、以及功能恢复相对较快等特点,近年来逐渐成为骨盆恶性或侵袭性肿瘤切除后的主要重建手段。但传统骨盆假体仍然存在断裂、松动等风险。随着3D打印技术的发展,采用3D打印定制类骨小梁多孔结构骨盆假体已成功应用于临床,获得了较好的力学支撑和界面骨整合,而假体的设计优劣和应用是否规范直接影响使用效果。本共识以循证医学证据为基础,经全国骨肿瘤专家商议讨论,从定制式3D打印骨盆肿瘤假体的设计和临床应用等关键技术环节形成推荐意见,为此类假体的有效使用提供参考。

关键词：骨盆肿瘤 3D打印假体

chinese guidelines for the application of colon cancer staging recognition systems based on artificial intelligence platforms (2021)

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Intelligent Medicine 2021年第1期1卷 37-42页

作者： Yun Lu Shuai Li Yuan Gao Yong Dai Bo Feng Fanghai Han Jiagang Han Jingjing He Xinxiang Li Guole Lin Qian Liu Guiying Wang Quan Wang Zhenning Wang Zheng Wang Aiwen Wu Bin Wu Yingchi Yang Hongwei Yao Wei Zhang Jianping Zhou Aimin Hao Zhongtao Zhang 无 Department of General Surgery The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266003China Beihang University State Key Laboratory of Virtual Reality Technology and Systems Beijing 100191China Department of General Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China Department of General Surgery Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200020China shanghai Minimally Invasive Surgery Center Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200020China Department of Gastrointestinal Surgery Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdong 510120China Department of General Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100027China Institute of International Law Chinese Academy of Social SciencesBeijing 102442China Department of Colorectal Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Third Hospital of Hebei Medical University ShijiazhuangHebei 50051China Department of Colon and Rectum Surgery The First Hospital of Jilin UniversityChangchunJilin 130031China Department of Surgical Oncology and General Surgery Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal TumorsMinistry of EducationThe First Affiliated Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education) Department of Unit II

The incidence and mortality of colon cancer in china are increasing each *** present,treatment selection for colon cancer patients mainly depends on imaging results,which require a large number of radiologists to *** china,there is a shortage and uneven distribution of experienced radiologists,which leads to delays and bias in the evaluation of imaging *** on these considerations,the Colorectal Surgery Group of the Surgery Branch of the chinese Medical Association in collaboration with experts at Beihang University has independently developed an artificial intelligence(AI)-based recognition system for the preoperative determination of colon cancer stage to partially replace the work of and relieve the pressure on *** guidelines aim to standardize the use of AI-based recognition systems in the preoperative staging of colon cancer and guide their clinical application.

关键词： Artificial intelligence Colon cancer Deep learning Preoperative staging

Investigation on the short-term outcome and prognostic impact of predisposition,and precipitants in inpatients with chronic liver disease from chinese AcuTe on CHronic LIver FailurE(CATCH-LIFE)cohorts

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Portal Hypertension & Cirrhosis 2023年第3期2卷 115-126页

作者： Yan Zhang Wenting Tan Xiaobo Wang Xin Zheng Yan Huang Beiling Li Zhongji Meng Yanhang Gao Zhiping Qian Feng Liu Xiaobo Lu Jia Shang Yubao Zheng Weituo Zhang Shan Yin Wenyi Gu Tongyu Wang Jianyi Wei Zixuan Shen Guohong Deng Yi Zhou Yixin Hou Qun Zhang Shue Xiong Jing Liu Liyuan Long Ruochan Chen Jinjun Chen Xiuhua Jiang Sen Luo Yuanyuan Chen Chang Jiang Jinming Zhao Liujuan Ji Xue Mei Jing Li Tao Li Rongjiong Zheng Xinyi Zhou Haotang Ren Yu Shi Hai Li for the CATCH‐LIFE Study Investigators of chinese(Acute‐on)Chronic Liver Failure(CLIF)Consortium(Ch‐CLIFC) Department of Gastroenterology Ren Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina shanghai Institute of Digestive Disease NHC Key Laboratory of Digestive DiseasesShanghaiChina Department of Infectious Diseases Southwest HospitalThird Military Medical University(Army Medical University)ChongqingChina Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijingChina Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Hunan Key Laboratory of Viral Hepatitis Department of Infectious DiseasesXiangya HospitalCentral South UniversityChangshaHunanChina Department of Infectious Diseases Hepatology UnitNanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Infectious Disease Taihe HospitalHubei University of MedicineShiyanHubeiChina Department of Hepatology The First Hospital of Jilin UniversityJilinChangchunChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghaiChina Tianjin Institute of Hepatology Nankai University Second People's HospitalTianjinChina Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinanShandongChina Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiangChina Department of Infectious Diseases Henan Provincial People's HospitalZhengzhouHenanChina Deparment of Infectious Diseases The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou CityGuangdongChina Clinical Research Center Shanghai Jiao Tong University School of MedicineShanghaiChina The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases The First Affiliated Hospital of School of MedicineZhejiang UniversityHangzhouZhejiangChina Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease HangzhouZhejiangChina Nati

Aim:The study aimed to investigate the short-term outcomes of hospitalized patients with chronic liver disease(CLDs)and assess the prognostic impact of predisposition and precipitants,which currently remains ***:The study included 3970 hospitalized patients with CLDs from two prospective longitudinal multicenter studies(NCT02457637 and NCT03641872)conducted in highly endemic hepatitis B virus(HBV)*** risk analysis was used to evaluate the effect of predispositions,including the etiology and severity of CLDs and precipitants;on sequential 28,90,and 365-day liver transplantation(LT)-free ***:Among all enrolled patients,76.8%of adverse outcomes(including death and LT)within one year occurred within 90 *** with alcoholic etiology,the association of HBV etiology with poorer outcomes was remarkably on the 28th day(hazard ratio[HR],1.81;95%confidence interval[CI],1.07-3.06;p=0.026);however,and dimin-ished or became insignificant at 90 days and 365 *** increased the adjusted risk for 365-day(HR,1.50;CI,1.13-1.99;p=0.004)LT-free mortality when compared with *** patients with cirrhosis,prior decompensation(PD)independently increased the adjusted risk of 365-day LT-free mortality by 1.25-fold(p=0.021);however,it did not increase the risk for 90-day *** the category nor the number of precipitants influenced the adjusted risk of 28 or 90-day LT-free ***:The 90-day outcome should be considered a significant endpoint for evaluating the short-term prognosis of hospitalized patients with *** factors,other than etiology,mainly affected the delayed(365-day)*** effective therapy for CLD etiology,especially antiviral treatments for HBV,and post-discharge long-term surveillance monitoring in cirrhotic patients undergoing PD are suggested to enhance disease management and reduce mortality.

关键词： cirrhosis precipitant prior decompensation short‐term mortality

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口腔外科开展继续医学教育的经验与思考

中国口腔颌面外科杂志 2018年第2期16卷 176-179页

作者：于海侯锐许广杰杨霞惠小勇周宏志丁宇翔薛洋胡开进军事口腔医学国家重点实验室国家口腔疾病临床医学研究中心陕西省口腔疾病临床医学研究中心第四军医大学口腔医院口腔外科陕西西安710032 第四军医大学研究生院陕西西安710032 中国人民解放军第413医院口腔科浙江舟山316000

继续医学教育是一种终生性医学教育制度。本文从口腔外科继续医学教育存在的问题入手,总结第四军医大学口腔医院口腔外科开展继续医学教育的经验,并探讨今后持续开展口腔外科继续医学教育的思路。

关键词：继续医学教育口腔外科医院管理

Short-term and oncological outcomes of natural orifice specimen extraction surgery(NOSES)for colorectal cancer in china:a national database study of 5055 patients

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Science Bulletin 2022年第13期67卷 1331-1334,M0003页

作者： Xu Guan Xiyue Hu Zheng Jiang Ye Wei Donghui Sun Miao Wu Haitao Zhou Hongliang Yao Junmin Song Guiyu Wang Junhong Hu Mingyang Ren Qing Xu Jianchun Cai Jian Peng Dan Ma Yangchun Zheng Qingsi He Bo Jiang Zejun Wang Taiyuan Li Su Yan Luchuan Chen Tiegang Li Zhiguo Xiong Pan Chi Liang Kang Gang Yu Xiaodong Deng Hong Zhang Ming Xie Jianbao Wei Hongyan Gong Xuejun Sun Weidong Zang Yongmao Song Peng He Zhengqi Wen Chunxu Zhang Yusheng Wang Yinggang Chen Guangwei Xie Mingzhang Li Shaojun Yu Haiying Liu Min Pu Chuangang Fu Xishan Wang on behalf of china NOSES Alliance Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of General Surgery Zhongshan HospitalFudan UniversityShanghai 200032China Department of Gastrointestinal and Anal Surgery Jilin University First HospitalChangchun 130021China Department of Gastrointestinal Surgery The Second People’s Hospital of YibinYibin 644000China Department of Gastrointestinal Surgery The Second Xiangya HospitalCentral South UniversityChangsha 410011China Department of Anorectal Surgery First Affiliated HospitalZhengzhou UniversityZhengzhou 450052China Department of Colorectal Cancer Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150081China Department of Gastrointestinal Surgery Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000China Department of Gastrointestinal Surgery Renji HospitalShanghai JiaoTong University School of MedicineShanghai 200240China Department of Gastrointestinal Surgery Zhongshan Hospital of Xiamen UniversityXiamen 361004China Department of General Surgery Xiangya HospitalCentral South UniversityChangsha 410008China Department of General Surgery Xinqiao HospitalThird Military Medical UniversityChongqing 400037China Department of Gastrointestinal Surgery Sichuan Cancer HospitalChengdu 610041China Department of General Surgery Shandong University Qilu HospitalJinan 250012China Department of Colorectal and Anal Surgery Shanxi Cancer HospitalTaiyuan 030013China Department of Gastrointestinal Surgery The Affiliated Cancer Hospital of Guizhou Medical UniversityGuiyang 550008China Department of General Surgery The First Affiliated Hospital of Nanchang UniversityNanchang 330006China Department of Gastrointestinal Surgery Qinghai University Affiliated HospitalXining 810012China Department of Gastrointestinal Surgery Fujian Medical University Cancer HospitalFuzhou 350014China Depar

经自然腔道取标本手术(NOSES)通过无切口理念与常规手术器械的结合,表现出极佳的微创效果,并带给患者全新的就医感受.目前,尽管NOSES已广泛用于结直肠肿瘤治疗,大量研究也表明相比常规腹腔镜手术,NOSES具有恢复快、创伤小、疼痛轻等优势... 详细信息

经自然腔道取标本手术(NOSES)通过无切口理念与常规手术器械的结合,表现出极佳的微创效果,并带给患者全新的就医感受.目前,尽管NOSES已广泛用于结直肠肿瘤治疗,大量研究也表明相比常规腹腔镜手术,NOSES具有恢复快、创伤小、疼痛轻等优势,但绝大多数研究均为小样本、单中心回顾性研究.本研究旨在通过分析我国5055例结直肠肿瘤NOSES患者数据,进一步探讨NOSES的短期疗效与预后.研究对象中,经直肠NOSES占整体比例的90.3%,经阴道NOSES占9.7%.NOSES术后短期并发症发生率为14.1%,吻合口瘘发生率为4.9%,腹盆腔感染率为1.9%.患者3年总生存率为93.2%,无病生存率为82.2%,局部复发率为3.6%.研究结果提示NOSES具有较好的安全性与可行性,为其应用于结直肠肿瘤治疗提供了证据.

关键词：结直肠肿瘤肿瘤学并发症发生率无病生存率吻合口瘘回顾性研究总生存率经直肠

建立帕金森病及相关运动障碍病三级全程化管理模式的方案

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中华老年医学杂志 2021年第7期40卷 813-821页

作者：中国医师协会神经内科医师分会帕金森病及运动障碍学组中华医学会神经病学分会帕金森病及运动障碍学组陈生弟陈海波王丽娟吴逸雯靳令经不详上海交通大学医学院附属瑞金医院神经内科、帕金森病诊疗研究中心 200025 北京医院神经内科、国家老年医学中心 100730 广东省人民医院神经内科同济大学附属养老康复医院神经康复中心

帕金森病(PD)及相关运动障碍病是老年人群中常见的一类疾病,对于该类疾病各地区医疗机构诊疗能力不平衡,区域内各级医疗机构的诊疗缺乏有效衔接,未能实现对运动障碍病全程管理的分工协作.本文结合我国国情,建立PD和运动障碍病三级全程... 详细信息

帕金森病(PD)及相关运动障碍病是老年人群中常见的一类疾病,对于该类疾病各地区医疗机构诊疗能力不平衡,区域内各级医疗机构的诊疗缺乏有效衔接,未能实现对运动障碍病全程管理的分工协作.本文结合我国国情,建立PD和运动障碍病三级全程管理模式,更好地实现疾病的规范化诊治、提高疾病改善率,降低疾病致残率.

关键词：帕金森病肌张力障碍原发性震颤运动障碍疾病管理