检索结果-南通市图书馆

A template of rat brain based on fMRI T2* imaging

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2005年第6期15卷 502-506页

作者： HU Zhenghui1, WU Yigen2, WANG Xiaochuan3. WANG Jianzhi3. CHEN Feiyan1 and TANG Xiaowei1*(1. Department of physics and Bio-X laboratory, Zhejiang University, Hangzhou 3.0027, China 2. institute of high energy physics and Key laboratory of nuclear analysis techniques, chinese academy of sciences,beijing 10003., China 3. Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 43.03., China) Department of physics and Bio-X laboratory Zhejiang University Hangzhou 310027 China Key laboratory of nuclear analysis {3. Institute of High Energy Physics Chinese Academy of Sciences Beijing 100039 China Department of Pathophysiology Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

The development of functional magnetic resonance imaging (fMRI) technology has made it possible to carry out functional brain imaging experiments in small animals. Usually, group data is required to form the assessment of population, which can not only increase the sensitivity of the overall experiment, but also allow the generalization of the conclusion to the whole population. In order to average the signals of functional brain images from different subjects, it is necessary to put all the mapping images into the same standard space (template image). However, up to now, most animal brain templates remain unavailable and it must be done by ourselves. In this study, a template image based on the brains of eight male Wistar rats is obtained, and it is successfully used in our present Alzheimer disease (AD)-like rat model studies as template for spatially normalizing images to the same stereotaxical space. The fMRI results processed with statistical parametric mapping (SPM99) software are in agreement with the results from immunohistochemical experiment, which proves that this method is universally applicable to the pathologic models of other small animals and to human brain lesion studies.

关键词： fMRI animal model atlas template normalization T*2.

Zircon and apatite fission track analyses on mineralization ages and tectonic activities of Tuwu-Yandong porphyry copper deposit in northern Xinjiang, China

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Earth sciences 2007年第12期50卷 1787-1795页

作者： YUAN WanMing1,BAO ZengKuan2,DONG JinQuan2,GUO ZhaoJie3.& DENG Jun1 1 State Key laboratory of Geological Processes and Mineral Resources,China University of Geosciences,beijing100083.China {3.,institute of high energy physics,chinese academy of sciences,beijing 10003.,China 3.Department of Geology,Peking University,beijing 100871,China State Key laboratory of Geological Processes and Mineral Resources China University of Geosciences Beijing China laboratory of nuclear analysis {3. Institute of High Energy Physics Chinese Academy of Sciences Beijing China Department of Geology Peking University Beijing China

The mineralization ages reported in the past in the Tuwu-Yandong copper district not only are different,but also fall into the Hercynian *** study has achieved 9 zircon and 7 apatite fission track analysis *** zircon fission track ages range from 158 Ma to 289 Ma and the apatite ages are between 64 Ma and 140 *** mineralization accords with the regional tectonics in the copper *** consider that the zircon fission track age could reveal the mineralization age based on annealing zone temperature of 140―3.0℃ and retention temperature of ～250℃ for zircon fission track,and metallogenetic temperature of 120―3.0℃ in this ore *** three mineralization epochs have been identified,i.e.,289―276 Ma,23.―200 Ma and 165―158 Ma,and indicate occurrence of the min-eralization in the Indosinian and Yanshan *** to apatite fission track ages,the three tectonic-mineralizing epochs are 140―13. Ma,109―97 Ma and 64 Ma,which means age at about 100℃ after the *** three epochs lasted 146 Ma,108 Ma and about 100 Ma from ～250℃ to ～100℃ and trend decrease from early to *** is shown by the fission track modeling that this district underwent three stages of geological thermal histories,stable in Cretaceous and cooling both before Cretaceous and after 20 Ma.

关键词： mineralization age, tectonic epoch, fission track, zircon, apatite, Tuwu-Yandong, Xinjiang

Correlation of Behavior Changes and BOLD Signal in Alzheimer-like Rat Model

在线全文

学校读者我要写书评

暂无评论

Acta Biochimica et Biophysica Sinica 2004年第12期36卷 803-810页

作者： Zheng-Hui HU#, Xiao-Chuan WANG1#, Li-Yun LI3. Mai-Li LIU3. Rong LIU1, Zhiqun LING1, Qing TIAN1, Xiao-Wei TANG, Yi-Gen WU2*, and Jian-Zhi WANG1* Department of physics and Bio-X disciplinary laboratory, Zhejiang University, Hangzhou 3.0027,China 1 Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 43.03., China 2institute of high energy physics and Key laboratory of nuclear analysis techniques, chinese academy of sciences, P.O. Box 918, beijing 10003., China 3.uhan institute of physics and Mathematics, State Key laboratory of Magnetic Resonance and Atomic and Molecular physics, chinese academy of sciences, Wuhan 43.071, China Department of physics and Bio-X disciplinary laboratory Zhejiang UniversityHangzhou 310027China Department of Pathophysiology Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030 China Wuhan institute of physics and Mathematics State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Chinese Academy of SciencesWuhan 430071 China institute of high energy physics and Key laboratory of nuclear {3. techniques Chinese Academy of SciencesP.O. Box 918 Beijing 100039 China

To explore a potential means for the early diagnosis of Alzheimer disease, we studied the relationship of resting T2* signal and tau hyperphosphorylation/spatial memory deficit. The rat model with tau hyperphosphorylation and spatial memory deficit was established by bilateral hippocampi injection of isoproterenol (IP). Then, the correlative alteration between resting T2* signal and spatial memory retention was assessed with blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) study and Morris Water Maze test, and Western blot was employed to confirm tau hyperphosphorylation. The analysis showed following results. (1) Tau phosphorylation at Ser3.6/Ser404 and Ser199/Ser202 was signifi- cantly increased in IP-injected rats as detected by PHF-1 and tau-1, respectively. (2) An AD-like spatial memory retention disturbance was induced at 24 h after isoproterenol injection. (3. A sensitivity threshold of resting T2* signal intensity, which separated the IP-treated rats from vehicle control, was obtained by applying linear regression analysis, and an estimated sensitivity statistical threshold was at 3..62. These results suggest that resting T2* signal may serve as a noninvasive quantitative marker in predicting AD-like spatial memory deficits and tau hyperphosphorylation.

关键词： Alzheimer disease (AD) functional magnetic resonance imaging (fMRI) isoproterenol (IP) Morris Water Maze diagnosis

Systematic distortion in cosmic microwave background maps

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(physics,Mechanics & Astronomy) 2009年第5期52卷 804-808页

作者： LIU Hao 1,3.&LI TiPei 1,2 1Key laboratory of Particle Astrophysics,institute of high energy physics,{3.,beijing 100049,China 2Center for Astrophysics,Tsinghua University,beijing 100084,China 3.Graduate University of {3.,beijing 100049,China Key laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing China Graduate University of chinese academy of sciences Beijing China Center for Astrophysics Tsinghua University Beijing China

To minimize instrumentally the induced systematic errors,cosmic microwave background(CMB)anisotropy experiments measure temperature differences across the sky using pairs of horn antennas, temperature map is recovered from temperature difference obtained in sky survey through a map-making *** inspect and calibrate residual systematic errors in the recovered temperature maps is important as most previous studies of cosmology are based on these *** analyzing pixel-ring coupling and latitude dependence of CMB temperatures,we find notable systematic devia- tion from CMB Gaussianity in released Wilkinson Microwave Anisotropy Probe(WMAP)*** detected deviation cannot be explained by the best-fit LCDM cosmological model at a confidence level above 99%and cannot be ignored for a precision cosmology study.

关键词： cosmology cosmic microwave background methods data analysis

New evidence for lack of CMB power on large scales

在线全文

学校读者我要写书评

暂无评论

Science China(physics,Mechanics & Astronomy) 2010年第3期53卷 567-570页

作者： LIU Hao1 & LI TiPei1,2,3.1 Key laboratory of Particle Astrophysics, institute of high energy physics, {3., beijing 100049, China 2 Department of physics & Center for Astrophysics, Tsinghua University, beijing 100084, China 3.Department of Engineering physics & Center for Astrophysics, Tsinghua University, beijing 100084, China Key laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing China Department of physics & Center for Astrophysics Tsinghua University Beijing China Department of Engineering physics & Center for Astrophysics Tsinghua University Beijing China

A digitalized temperature map is recovered from the first light sky survey image published by the Planck team, from which an angular power spectrum of the cosmic microwave background (CMB) is derived. The amplitudes of the low multipoles (low-l) measured from the preliminary Planck power spectrum are significantly lower than those reported by the WMAP team. Possible systematical effects are far from enough to explain the observed low-l differences.

关键词： cosmology cosmic microwave background data analysis

Properties of the 3.2^-[521] band in the odd-N rare-earth nuclei

在线全文

学校读者我要写书评

暂无评论

Science China(physics,Mechanics & Astronomy) 2011年第S1期54卷 37-43页

作者： CHEN Liang1,2, ZHOU XiaoHong1,2, ZHANG YuHu1, ZHANG ShuangQuan3.& ZHU LiHua4 1institute of Modern physics, chinese academy of sciences, Lanzhou 73.000, China 2Graduate University of chinese academy of sciences, beijing 100049, China 3.tate Key laboratory of nuclear physics and Technology, School of physics, Peking University, beijing 100871, China 4China institute of Atomic energy, beijing 102413. China institute of Modern physics Chinese Academy of Sciences Lanzhou China Graduate University of chinese academy of sciences Beijing China State Key laboratory of nuclear physics and Technology School of Physics Peking University Beijing China China institute of Atomic energy Beijing China

high-spin states in 161Er have been studied experimentally via the 150Nd(16O, 5n) reaction at a beam energy of 86 MeV. Three rotational bands built on the 5/2+[642], 3.2-[521], and 11/2-[505] configurations have been extended up to high-spin states, and particularly, the α = -1/2 branch of the ground state 3.2-[521] band has been revised significantly. It is found that signature inversion occurs in the 3.2-[521] band after the band crossing in 161Er. The systematics of the signature inversion associated with the 3.2-[521] configuration in the rare-earth region is discussed. The band properties are analyzed within the framework of a triaxial particle-rotor model, and a triaxial deformation is proposed to the 3.2-[521] band.

关键词： high-spin states signature inversion triaxial particle-rotor model

Heavy ion reactions around the Coulomb barrier

在线全文

学校读者我要写书评

暂无评论

中国科学：物理学、力学、天文学英文版 2011年第S1期54卷 6-13页

作者： ZHANG HuanQiao1, LIN ChengJian1, JIA HuiMing1, ZHANG ChunLei1,2, ZHANG GaoLong1,3. YANG Feng1, LIU ZuHua1, AN GuangPeng1, WU ZhenDong1, XU XinXing1 & JIA Fei1 1 China institute of Atomic energy, P. O. Box 275(10), beijing 102413. China 2 Particle Astro{3. Center, institute of high energy physics, chinese academy of sciences, beijing 10003., China 3.School of {3. and nuclear energy Engineering, Beihang University, beijing 100191, China China institute of Atomic energy Beijing China Particle Astrophysics Center Institute of High Energy Physics Chinese Academy of Sciences Beijing China School of physics and nuclear energy Engineering Beihang University Beijing China

The angular distributions of fission fragments for the 3.S+184W reaction near Coulomb barrier energies are measured. The ex perimental fission excitation function is obtained. The measured fission cross sections are decomposed into fusion-fission, quasi-fission and fast fission contributions by the dinuclear system (DNS) model. The hindrance to completing fusion both at small and large collision energies is explained. The fusion excitation functions of 3.S+90,96Zr in an energy range from above to below the Coulomb barrier are measured and analyzed within a semi-classical model. The obvious effect of positive Q-value multi-neutron transfers on the sub-barrier fusion enhancement is observed in the 3.S+96Zr system. In addition, the excitation functions of quasi-elastic scattering at a backward angle have been measured with high precision for the systems of 16O+208Pb, 196Pt, 184W, and 154,152Sm at energies well below the Coulomb barrier. Considering the deformed coupling effects, the extracted diffuseness parameters are close to the values extracted from the systematic {3. of elastic and inelastic scattering data. The elastic scattering angular distribution of 17F+12C at 60 MeV is measured and calculated by using the continuum-discretized coupled-channels (CDCC) approach. It is found that the diffuseness parameter of the real part of core-target potential has to be increased by 20% to reproduce the experimental result, which corresponds to an increment of potential depth at the surface re gion. The breakup cross section and the coupling between breakup and elastic scattering are small.

关键词： fusion-fission quasi-fission fusion hindrance fusion enhancement surface diffuseness parameter exotic nuclei

Deprojection technique for galaxy cluster considering the point spread function

在线全文

学校读者我要写书评

暂无评论

Science China(physics,Mechanics & Astronomy) 2010年第S1期53卷 183-186页

作者： WANG YuSa,JIA ShuMei & CHEN Yong Key laboratory for Particle Astrophysics,institute of high energy physics,{3.,beijing 100049,China Key laboratory for Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing China

We present a new method for the analysis of Abell 183. observed by *** method is a combination of the Direct Demodulation technique and *** eliminate the effects of the point spread function(PSF) with the Direct Demodulation *** then use a traditional deprojection technique to study the properties of Abell *** to only using a deprojection method,the central electron density derived from this method increases by 3.%,while the temperature profile is similar.

关键词： PSF Direct Demodulation deprojection Abell 183. galaxy cluster XMM-Newton

Inconsistency between WMAP data and released map

在线全文

学校读者我要写书评

暂无评论

chinese Science Bulletin 2010年第10期55卷 907-909页

作者： LIU Hao1 & LI TiPei1,2,3.1 Key laboratory of Particle Astrophysics,institute of high energy physics,{3.,beijing 100049,China 2 Department of physics & Center for Astrophysics,Tsinghua University,beijing 100084,China 3.Department of Engineering physics & Center for Astrophysics,Tsinghua University,beijing 100084,China Key laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing China Department of physics & Center for Astrophysics Tsinghua University Beijing China Department of Engineering physics & Center for Astrophysics Tsinghua University Beijing China

A remarkable inconsistency between the calibrated differential time-ordered data (TOD) of the Wilkinson Microwave Anisotropy Probe (WMAP) mission,which is the input for map-making,and the cosmic microwave background (CMB) temperature maps published by the WMAP team is revealed,indicating that there must exist a serious problem in the map making routine of the WMAP *** inconsistency is easy to be confirmed without the use of WMAP map-making *** view of the importance of this issue for cosmology study,we invite readers to check it by themselves.

关键词：威尔金森微波各向异性探测器 WMAP 地图制作宇宙微波背景有序数据制作软件 TOD CMB