检索结果-南通市图书馆

The Clinical Study and HLA Genotyping of 112 Familial Myasthenia Gravis Patients

在线全文

学校读者我要写书评

暂无评论

Journal of Huazhong university of Science and Technology(Medical Sciences) 1999年第1期19卷 47-50页

作者：卜碧涛杨明山徐金枝龚非力姜晓丹聂小波

Summary: One hundred and twelve cases of familial myasthenia gravis (MG) from 44 families selected from 2100 patients with MG diagnosed since 1983 in the department of Neurology were studied. The clinical pictures and immunological features of the patients showed a great resemblance to those of sporadic cases. The pedigree analysis disclosed that the hereditary patterns of familial patients were basically Mendellian autosomal inheritance. Many predisposing factors such as fever, infection, use of aminoglycoside or vaccines, played an important role in presenting the phenotype of subclinical cases. The HLA genotyping suggested that the complement polymorphism C4A*4, the complotype S42, and the genes 0901 and 1301 of DRB1 allele, were related to the pathogenesis of MG. It was concluded that the phenotype of MG may be the result of interaction between hereditary defects and environmental factors.

关键词： familial myasthenia gravis Mendellian autosomal inheritance HLA genotyping pedigree analysis

Construction of cDNA library and Analysis on Expressed Sequence Tags of Polygonum multiflorum *** tissue

在线全文

学校读者我要写书评

暂无评论

Construction of cDNA library and Analysis on Expressed Seque...

2010年广东省药师周大会

作者： TAN Xue-Mei1),SHEN Yan-Jing1),YAN Ping2),ZHENG Chuan-jin1),ZHAO Shu-jin1) (1).department of Pharmacy,Guangzhou General Hospital of Guangzhou Military Command,Guangzhou 510010,China 2).Guangdong Institute for Drug Control,Guangzhou 510180,China)

To construct a cDNA library of mature leaves( Polygonum multiflorum Thunb.),so as to further research the gene regulation of secondary metabolite biosynthesis of *** RNA was extracted with improved CTAB method and mRNA was purified by oligo(dT)-cellulose column chromatography,which were synthesized to double strands through reverse transcription。After blunting the cDNA termini,the 5’end of EcoR I adapters phosphorylated were conjoined and then digested by Xho I。cDNA fragments less than 400bp were eliminated by Sepharose CL-2B spin column,and then ligated to uni-λZAP XR *** mixture of ligation was finally packed into lambda virus with packaging *** the primary library had been finished,0.54×106 recombinations had been obtained,and the length of exogenous insert at about 0.5～2.0kb。The amplified library had 4.25×1011 recombinations and the rate of recombination was 98.5%。16 bacteriophage plaques were randomly selected to identify the size range of inserts by PCR。Continued to pick 12 bacteriophage plaques and extracted pBluescript SKphasmids ,which were inverted by the action of ExAssist helper phage。Phasmids,which extracted by alkaline lysis,digested via EcoR I and Xho I and identified the size of *** used the method of PCR and double enzymes digestion to identify the size of *** present,30 positive clones in vivo excision of the pBluescript phagemid from the uniλZAP XR *** been picked and extracted plasmid to carry out to sequence 3’*** results indicated that the cDNA library of Polygonum multiflorum *** enough volume for screening desired genes .Totally,it was the first time to construct a cDNA library and sequence 3’-ESTs of Polygonum multiflorum thunb.,it should enrich the plant genome research database and promote the study of gene regulation of secondary metabolite biosynthesis of offcinal,which lays a foundation for functional gene screening and analysis.

关键词： Polygonum multiflorum Thunb. cDNA library functional gene expressed sequence Tags

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

基于BP神经网络的弱信号提取方法研究

数据采集与处理 1997年第3期12卷 163-166页

作者：杨建华侯宏孙进才周庆余西北工业大学自动控制系西安710072 西北工业大学物理系西安710072 西北工业大学声学所西安710072

提出一种基于BP神经网络结构与算法的弱信号提取方法，该方法在网络节点连接权向量域，从宽带背景噪声中提取弱信号，且对信号的先验知识没有要求。文中具体给出了BPWV方法的原理及推导过程。仿真结果表明，该方法能显著地提高信噪比。

关键词：信号检测信噪比经济网络信号提取

在线全文

学校读者我要写书评

暂无评论

嗜神经型新城疫病毒野毒株的电镜观察

山东师范大学学报（自然科学版） 1998年第4期13卷 431-433页

作者：刘红冯成强于明秦卓明山东省农科院家禽研究所SPF种鸡场山东师范大学生物学系东北农业大学生物学系

采用钼酸铵负染色方法，电镜观察一株野外分离的嗜神经型新城疫病毒．分离的毒株接种ＳＰＦ鸡胚后，收集尿囊液，在电镜下可看到大量圆形或扁圆形、直径２００～３００ｎｍ的病毒颗粒，并且，部分病毒粒子囊膜及纤突清晰可见．

关键词：新城疫病毒野毒株电镜嗜神经型鸡

在线全文

学校读者我要写书评

暂无评论

化学驱中相态变化对驱油效率的影响

新疆石油地质 2002年第5期23卷 411-414页

作者：陈民锋郎兆新石油大学石油工程系北京102200

研究了化学驱过程中的相态变化,以及在不同相态下的毛管数对相对渗透率曲线端点值、指数值和残余油饱和度等的重要影响;结合实验数据,计算了不同毛管数下和具有不同润湿性岩石的驱油效率,得出在化学驱过程中,应尽量维持最佳驱替体系,使... 详细信息

研究了化学驱过程中的相态变化,以及在不同相态下的毛管数对相对渗透率曲线端点值、指数值和残余油饱和度等的重要影响;结合实验数据,计算了不同毛管数下和具有不同润湿性岩石的驱油效率,得出在化学驱过程中,应尽量维持最佳驱替体系,使驱替相保持较高的毛管数,以达到最大限度地提高采收率的目的。

关键词：化学驱油毛管数相对渗透率曲线驱油效率残余油

Virasoro规范理论的Hamilton形式

在线全文

学校读者我要写书评

暂无评论

黄淮学刊（自然科学版） 1997年第2期13卷 24-27页

作者：王杰芳程启华河南医科大学郑州450052 北京CCAST(世界实验室)

根据物质场和不带中心荷的Virasoro群规范场之间的规范不变的相互作用的Lagrange密度函数，我们构造了Hamilton形式，推导了规范场的运动方程和找出了所有初级约束．同时，我们猜测，体系的次级约束可能是无穷多的！

关键词： Virasoro群规范理论规范场哈密尔顿形成

在线全文

学校读者我要写书评

暂无评论

电场作用下高分子中自陷束缚激子的极化

物理学报 1998年第1期47卷 94-101页

作者：傅柔励叶红娟李蕾傅荣堂缪健孙鑫张志林中国科学院上海技术物理研究所红外物理国家重点实验室复旦大学李政道物理学综合实验室上海大学嘉定分校材料学院

用同时计入电场、对称破缺项ｔｅ和电子晶格相互作用的紧束缚模型研究了电场作用下高分子中的自陷束缚激子．发现电场使高分子中自陷束缚激子内电荷发生转移，出现极化．极化程度随场强增加，也与ｔｅ有关．并发现ｔｅ≤０．１ｅＶ时... 详细信息

用同时计入电场、对称破缺项ｔｅ和电子晶格相互作用的紧束缚模型研究了电场作用下高分子中的自陷束缚激子．发现电场使高分子中自陷束缚激子内电荷发生转移，出现极化．极化程度随场强增加，也与ｔｅ有关．并发现ｔｅ≤０．１ｅＶ时，双激子态表现出反向极化特性，这一特性可根据极化的量子力学理论得到理解：对高分子的自陷束缚激子，其禁带中央附近存在两个靠得很近的定域电子态即上定域态和下定域态，用微扰论说明了上定域态是反向极化而下定域态为正向极化；双激子态即上定域态被占而下定域态空着，当ｔｅ不大时，双激子态的极化就是反向的．

关键词：电致发光器件电场高分子自陷束缚激子极化

在线全文

学校读者我要写书评

暂无评论

早产儿肺透明膜病的发病因素分析

新生儿科杂志 2000年第2期15卷 59-60页

作者：王颖王浩云郭在晨北京医科大学第一医院 100034 邯郸市峰峰矿务局职工医院 056201

For understand the incidence and risk factors of hyaline membrane disease (HMD)article analyzed 145 premature infants. It has found that 21 cases developed HMD and 14. 7% of the total newborns. The frequency of HMD was higher in males than in females. The incidence of HMD with different week of gestation differed greatly. It showed that for 28-30, 31-32, 33 -34, 35-36 weeks of gestation were 38. 46%, 20% 14. 8%, 4. 17% separately. It was ana- alyzed in statistics by Logistic regression the development of HMD have direct relation with week of gestation, weight of birth,degree of asphyxia (Apgar score), cesarean section, pre- mature rupture of the membrane and using dexamethason before infant birth(p<0. 01).

关键词：早产儿肺透明膜病病因高危因素

Stimulated　Raman　Effect　in　Bi-directionally　Amplified　and　Transmision　WDM　Systems

在线全文

学校读者我要写书评

暂无评论

Communications in Nonlinear Science and Numerical Simulation 1997年第2期2卷 30-34页

作者： Kan ZHANG, Anshi XU, Deming WU & Linzhen XIE (National Laboratory of Local Fiber-Optic Communication Networks & Advanced Optical Communication Systems, department of Electronics, Peking university, Beijing, 100871) E-mail: ken@*** National Laboratory of Local Fiber-Optic Communication Networks & Advanced Optical Communication Systems Department of Electronics Peking University Beijing 100871 China

ＳｔｉｍｕｌａｔｅｄＲａｍａｎＥｆｅｃｔｉｎＢｉ－ｄｉｒｅｃｔｉｏｎａｌｙＡｍｐｌｉｆｉｅｄａｎｄＴｒａｎｓｍｉｓｉｏｎＷＤＭＳｙｓｔｅｍｓ１ＫａｎＺＨＡＮＧ，ＡｎｓｈｉＸＵ，ＤｅｍｉｎｇＷＵ＆ＬｉｎｚｈｅｎＸＩＥ（... 详细信息

ＳｔｉｍｕｌａｔｅｄＲａｍａｎＥｆｅｃｔｉｎＢｉ－ｄｉｒｅｃｔｉｏｎａｌｙＡｍｐｌｉｆｉｅｄａｎｄＴｒａｎｓｍｉｓｉｏｎＷＤＭＳｙｓｔｅｍｓ１ＫａｎＺＨＡＮＧ，ＡｎｓｈｉＸＵ，ＤｅｍｉｎｇＷＵ＆ＬｉｎｚｈｅｎＸＩＥ（ＮａｔｉｏｎａｌＬａｂｏｒａｔｏｒ...

关键词： WDM Bi-directional Transmission SRS EDFA Bi-directional Amplifier