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An embryological study and systematic significance of the primitive gymnosperm Ginkgo biloba

Journal of Systematics and Evolution 2011年第4期49卷 353-361页

作者： 1,2li wang 1di wang 1ming-ming lin 1yan lu 1xiao-xue jiang 1biao jin 1(College of Horticulture and Plant Protection,yangzhou University,yangzhou 225009,China) 2(Key Laboratory of Photosynthesis and Environmental Molecular Physiology,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China) (College of Horticulture and Plant Protection Yangzhou University Yangzhou 225009 China) (Key Laboratory of Photosynthesis and Environmental Molecular Physiology Institute of Botany Chinese Academy of Sciences Beijing 100093 China)

Ginkgo biloba *** considered one of the most ancient seed plants,with several primitive features of plant reproductive ***,the phylogenetic position of Ginkgo and its relationship with other extant seed plants remain *** gain a better understanding of these issues,we observed the embryological development of *** using semi-thin sections and scanning electron *** late August,the zygote moved from the end of the micropylar to the middle of the archegonium,and mitosis resulted in many free nuclei distributed randomly in the ***,the cell wall was formed and the proembryo began to differentiate into the embryonal region and the underdeveloped presuspensor *** early October,the embryo differentiated into two cotyledons,plumule,hypocotyl,radicle,and suspensor ***,the two cotyledons grew rapidly,but the undeveloped suspensor began to degenerate and gradually disappear,indicating that the embryo had begun to *** early embryo development,the main supply of nutrients was carbohydrate in the cells of the jacket,tentpole,and surrounding endosperm,whereas endosperm provided nutrients during embryo *** results indicate that Ginkgo is extremely similar to cycads in terms of embryology but more similar to conifers in macromorphology and vegetative anatomy,suggesting that the Ginkgo lineage may have an intermediate phylogenetic position between cycads and conifers.

关键词： embryo development Ginkgo biloba L. systematic significance.

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Gas microchannel plate-pixel detector for X-ray polarimetry

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Nuclear Science and Techniques 2024年第5期35卷 60-73页

作者： Huan-Bo Feng Hong-Bang liu Dong wang Zi-li li Shu-lin liu Qian liu Hang-Zhou li Bin-Long wang yan-Jun Xie Zong-wang Fan Hui wang Ran Chen di-Fan Yi Rui-Ting Ma Fei Xie Bo Peng Xiang-ming Sun jin li En-Wei liang Present Address:Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China PLAC Key Laboratory of Quark and Lepton Physics(MOE)Central China Normal UniversityWuhan 430079China School of Science Huzhou UniversityHuzhou 313000China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China School of Physical Science University of Chinese Academy of SciencesBeijing 100049China The 13th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050057China

POLAR-2 is a gamma-ray burst(GRB)polarimeter that is designed to study the polarization in GRB radiation emissions,aiming to improve our knowledge of related ***-2 is expected to utilize an on-board polarimeter that is sensitive to soft X-rays(2-10 keV),called low-energy polarization *** have developed a new soft X-ray polari-zation detector prototype based on gas microchannel plates(GMCPs)and pixel chips(Topmetal).The GMCPs have bulk resistance,which prevents charging-up effects and ensures gain stability during *** detector is composed of low outgassing materials and is gas-sealed using a laser welding technique,ensuring long-term stability.A modulation factor of 41.28%±0.64% is obtained for a 4.5 keV polarized X-ray beam.A residual modulation of 1.96%±0.58% at 5.9 keV is observed for the entire sensitive area.

关键词： X-ray polarimetry Gas microchannel plate-pixel detector Gamma-ray bursts

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Heat exposure and hospitalizations for chronic kidney disease in China: a nationwide time series study in 261 major Chinese cities

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Military Medical Research 2024年第4期11卷 469-478页

作者： Fu-lin wang Wan-Zhou wang Fei-Fei Zhang Su-Yuan Peng Huai-Yu wang Rui Chen jin-Wei wang Peng-Fei li yang wang ming-Hui Zhao Chao yang lu-Xia Zhang Institute of Medical Technology Peking University Health Science CenterBeijing 100191China National Institute of Health Data Science at Peking University Beijing 100191China Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijing 100191China Renal division Department of MedicinePeking University First HospitalPeking University Institute of NephrologyBeijing 100034China Research Units of diagnosis and Treatment of Immune-Mediated Kidney diseases Chinese Academy of Medical SciencesBeijing 100034China Advanced Institute of Information Technology Peking UniversityHangzhou 311215China National Climate Center China Meteorological AdministrationBeijing 100081China Peking-Tsinghua Center for life Sciences Beijing 100034China

Background:Climate change profoundly shapes the population health at the global ***,there was still insufficient and inconsistent evidence for the association between heat exposure and chronic kidney disease(CKD).Methods:In the present study,we studied the association of heat exposure with hospitalizations for cause-specific CKD using a national inpatient database in China during the study period of hot season from 2015 to *** time-series regression models and random-effects Meta-analysis were developed to estimate the city-specific and national averaged associations at a 7 lag-day span,***:A total of 768,129 hospitalizations for CKD was recorded during the study *** results showed that higher temperature was associated with elevated risk of hospitalizations for CKD,especially in sub-tropical *** a 1℃ increase in daily mean temperature,the cumulative relative risks(RR)over lag 0-7 d were 1.008[95% confidence interval(CI)1.003-1.012]for *** attributable fraction of CKD hospitalizations due to high temperatures was 5.50%.Stronger associations were observed among younger patients and those with obstructive *** study also found that exposure to heatwaves was associated with added risk of hospitalizations for CKD compared to non-heatwave days(RR=1.116,95%CI 1.069-1.166)above the effect of daily mean ***:Short-term heat exposure may increase the risk of hospitalization for *** findings provide insights into the health effects of climate change and suggest the necessity of guided protection strategies against the adverse effects of high temperatures.

关键词： Chronic kidney disease Hospitalization Climate change Temperature Time-series study

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Single-cell and bulk transcriptomics identifies a tumor-specific CD36+cancer-associated fibroblast subpopulation in colorectal cancer

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Cancer Communications 2024年第4期44卷 495-498页

作者： jin wang ming-Jia Xi Qing lu Bi-Han Xia Yu-Zhi liu jin-lin yang Department of Gastroenterology and Hepatology West China HospitalSichuan UniversityChengduSichuanP.R.China Sichuan University-University of Oxford Huaxi Joint Center for Gastrointestinal Cancer Frontiers Science Center for Disease-Related Molecular NetworkWest China HospitalSichuan UniversityChengduSichuanP.R.China

Dear Editor,Cancer-associated fibroblasts(CAFs)are highly ver-satile and plastic cells in the tumor *** have been identified as actively involved in can-cer progression and metastasis through their various roles in remodeling the extracellular matrix,suppressing the immune response and reprogramming tumor metabolism[1].However,many challenges exist in revealing the func-tional phenotypes and mechanisms of CAFs in different cancers due to limited understanding of CAF hetero-geneity[2].

关键词： CD36 metabolism colorectal

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Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor

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Science China(life Sciences) 2024年第7期67卷 1502-1513页

作者： luo-Yuan Xia xue-Feng wang xiao-ming Cui Yi-ming Zhang Zhen-Fei wang En-Tao li Chang-Fa Fan Ke Song Yuan-Guo li Run-Ze Ye Fang-Xu li Dai-Yun Zhu Jie Zhang Zhuang-Zhuang Shi ming-Zhu Zhang liang-jing li Shi-jing Shen Song jin Ya-Wei Zhang Wei-Guang Fu lin Zhao Wen-Hao wang Tie-Cheng wang You-Chun wang Jia-Fu jiang yan-ling Hu Na Jia Yu-Wei Gao Wu-Chun Cao Institute of EcoHealth School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China Changchun Veterinary Research Institute Changchun 130122China State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyBeijing 100071China division of Animal Model Research Institute for Laboratory Animal ResourcesNational Institutes for Food and Drug ControlBeijing 102629China National Institutes for Food and Drug Control Beijing 102629China life Sciences Institute Guangxi Medical UniversityNanning 530020China College of life Sciences Shandong Normal UniversityJinan 250014China Research Unit of discovery and Tracing of Natural Focus diseases Chinese Academy of Medical SciencesBeijing 100071China

Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins,showing a potential threat to *** we report the infectivity and pathogenicity of the SARS-CoV-2-related virus,PCoV-GX/P2V,which was isolated from a Malayan pangolin(Manis javanica).PCoV-GX/P2V could grow in human hepatoma,colorectal adenocarcinoma cells,and human primary nasal epithelial *** replicated more efficiently in cells expressing human angiotensin-converting enzyme 2(hACE2)as SARS-CoV-2 *** intranasal inoculation to the hACE2-transgenic mice,PCoV-GX/P2V not only replicated in nasal turbinate and lungs,but also caused interstitial pneumonia,characterized by infiltration of mixed inflammatory cells and multifocal alveolar *** population immunity established by SARS-CoV-2 infection and vaccination may not protect people from PCoV-GX/P2V *** findings further verify the hACE2 utility of PCoV-GX/P2V by in vivo experiments using authentic viruses and highlight the importance for intensive surveillance to prevent possible cross-species transmission.

关键词： pangolin SARS-CoV-2-related virus infectivity pathogenicity human cell lines human ACE2 receptor hACE2-transgenic mice

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Dynamically lithium-compensated polymer artificial SEI to assist highly stable lithium-rich manganese-based anode-free lithium metal batteries

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Rare Metals 2024年第6期43卷 2527-2535页

作者： ming-Ji Peng jin-Qiu Zhou Ting-Ting Han yang Zhou Jie liu Na Xu Zhen-Kang wang Wen-Bin lin Cheng-lin yan Key Laboratory of Core Technology of High Specific Energy Battery and Key Materials for Petroleum and Chemical Industry College of EnergySoochow UniversitySuzhou 215006China light Industry Instituteof Electrochemical Power Sources Suzhou 215006China School of Chemistry and Chemical Engineering Nantong UniversityNantong 226019China e-mail:jliu93@*** State Key Laboratory of Space Power-Sources Technology Shanghai Institute of Space Power-SourcesShanghai 200245China Centre Energie Materiaux et TélécommunicationsInstitut National de la Recherche ScientifiqueVarennesQC J3X 1S2Canada Zhangjiagang Industrial Technologies Soochow UniversitySuzhou 215006China

Owing to the unique structure,anode-free lithium metal batteries(AFLMBs)have higher energy density and lower production cost than traditional lithium metal batteries(LMBs)or lithium-ion batteries(liBs),However,AFLMBs suffer from an inherently finite li reservoir and exhibit poor cycle stability,low Coulombic efficiency(CE)and severe dendrite *** this work,polydiallyl lithium disulfide(PDS-li)was successfully synthesized and coated on Cu current collector by electrochemical *** PDS-li acts as an additional lithium resource to compensate for the irreversible loss of lithium during *** addition,the special structure and lithiophilicity of PDS-li contribute to lower nucleation overpotential and uniform lithium *** coupled with li-rich manganese-based(LRM)cathode of li1.2Mn0.54Ni0.13Co0.13O2,the anode-free full cell exhibits significantly improved cycle stability over 100 cycles and capacity retention of 63.3%and 57%after 80 and 100 cycles,*** believe that PDS-li can be used to ensure stable cycling performance and high-energy-density in AFLMBs.

关键词： Anode-free Artificial solid electrolyte interphase(SEI) lithium metal batteries lithium-rich cathode Finite element simulation

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Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang Wen Huang Fu-Jie Yu Qi Zhao Xin-Dong Zhu Tao Feng Yao jiang xiao-ming li xue-Fei Miao He Zhu Si Lan xue-Qian wang Bao-Long Shen Zhe Jia Feng-Qi Zhang Wei wang Qi liu yang Ren Xun-li wang xiao-Ya Cui xiao-yang wang Ya-Nan Chen Bing-Bing Fan Meng-Ru li Qi-Long Gao Jia-ming Guo Zeng-Bao Jiao Zhi-Min Guo Yu-Ping Zhao Qian Yu Rui Huang ling-Kun Zhang Yi-Ping lu Xu-Bo li Huai-Jun lin yan Ma Wei-ming yang Zhi-Hua Shen Hai-yan He Yong-Gang Sun Yong-jiang Huang De-Zhuang wang Qing-Feng liu Fei-yang wang Hui liu Hong-Hui Wu li-Qiang wang yang lu Nan wang Tian-li wang Wei-Bing liao Yi-Han wang Yuan Wu Yu-Zhen Yin Jie Pan Yi Zhang Qing wang Jian-yang Zhang Tao yang Yasir Sohail jin-Yu Zhang Hua Ji Qiang li Wei-di liu Zhi-Gang Chen Xiong-Jun liu Wen Ma liang Mao Zhen-Duo Wu School of Materials Science and Engineering Nanjing University of Science and Technology jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and Engineering Southeast University Department of Physics City University of Hong Kong School of Materials Science and Engineering Tianjin University School of Physics and Microelectronics Zhengzhou University Department of Mechanical Engineering Research Institute for Advanced Manufacturing The Hong Kong Polytechnic University Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and Engineering Zhejiang University Key Laboratory of Solidification Control and digital Preparation Technology (liaoning Province) School of Materials Science and Engineering Dalian University of Technology Institute of Advanced Wear & Corrosion Resistance and Functional Materials Jinan University School of Mechanics and Civil Engineering China University of Mining and Technology School of Physical Sciences Great Bay University School of Materials Science andEngineering Harbin Institute of Technology State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon Neutrality University of Science and Technology Beijing Department of Mechanical Engineering The University of Hong Kong School of Computing Macquarie University Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen University State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing State Key Laboratory of Materials Processing and die & Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology Institute of materials Shanghai University Department of Materials Science and Engineering C

Owing to their exceptional properties, high-entropy alloys(HEAs) and high-entropy materials have emerged as promising research areas and shown diverse applications. Here,the recent advances in the field are comprehensively reviewed,organized into five sections. The first section introduces the background of HEAs, covering their definition, significance,application prospects, basic properties, design principles, and microstructure. The subsequent section focuses on cutting-edge high-entropy structural materials, highlighting developments such as nanostructured alloys, grain boundary engineering,eutectic systems, cryogenic alloys, thin films, micro-nano-lattice structures, additive manufacturing, high entropy metallic glasses, nano-precipitate strengthened alloys, composition modulation, alloy fibers, and refractory systems. In the following section, the emphasis shifts to functional materials, exploring HEAs as catalysts, magneto-caloric materials, corrosion-resistant alloys, radiation-resistant alloys, hydrogen storage systems, and materials for biomedicine. Additionally, the review encompasses functional high-entropy materials outside the realm of alloys, including thermoelectric, quantum dots, nanooxide catalysts, energy storage materials, negative thermal expansion ceramics,and high-entropy wave absorption materials. The paper concludes with an outlook, discussing future directions and potential growth areas in the field. Through this comprehensive review,researchers, engineers, and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： Cutting-edge structural materials Cutting-edgefunctional materials High entropy alloys

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enOsCas12f1-mediated exon skipping for Duchenne muscular dystrophy therapy in humanized mouse model

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Journal of Genetics and Genomics 2024年第2期51卷 256-259页

作者： ming jin Jiajia lin Yu Zhang Qingquan xiao Xiangfeng Kong Xiumei Zhang Zhurui Shao Yin wang Yuyang Yu jinjing li Wan-jin Chen Guoling li Hui yang Ning wang Department of Neurology and Institute of Neurology of First Affiliated Hospital Institute of NeuroscienceFujian Key Laboratory of Molecular NeurologyFujian Medical UniversityFuzhouFujian 350004China HUIDAGENE Therapeutics Co. Ltd.Shanghai 200131China Institute of Neuroscience State Key Laboratory of NeuroscienceKey Laboratory of Primate NeurobiologyCAS Center for Excellence in Brain Science and Intelligence TechnologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200031China

Duchenne muscular dystrophy(DMD)is a severe neuromuscular disorder caused by mutations in the dystrophin gene,which encodes the essential protein *** genetic condition,affecting approximately 1 in 5000 male births worldwide(Birnkrant et al.,2018),is characterized by progressive muscle weakness and wasting,leading to premature death in the second or third decade of life(Farini et al.,2016).The absence of dystrophin protein causes instability in the sarcolemma,which predisposes individuals to myonecrosis and activation of inflammatory signaling ***,there is currently no effective cure for DMD,and glucocorticoid steroids are commonly used in clinical settings to delay symptom development(Merlini et al.,2003).

关键词： dystrophy Duchenne

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Electrochemical reconstruction: a new perspective on Sn metal-organic complex microbelts as robust anode for lithium storage

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Rare Metals 2024年第1期43卷 76-86页

作者： jin-Ke Shen Nai-Teng Wu li-Yuan wang Gang jiang Dong-Lei Guo jin li Gui-Long liu Hong-Yu Mi Huan Pang Xian-ming liu Key Laboratory of Function-oriented Porous Materials of Henan Province College of Chemistry and Chemical EngineeringLuoyang Normal UniversityLuoyang 471934China State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources School of Chemical Engineering and TechnologyXinjiang UniversityUrumqi 830046China School of Chemistry and Chemical Engineering Institute for Innovative Materials and EnergyYangzhou UniversityYangzhou 225009JiangsuChina

Tin-based materials with high theoretical capacity and suitable working voltage are ideal anode materials for lithium-ion batteries(liBs). However, to overcome their shortcomings(volume expansion and inferior stability), the preparation processes are usually complicated and expensive. Herein, a tin-based metal-organic complex(tin 1,2-benzenedicarboxylic acid, Sn-BDC)with one-dimensional microbelt morphology is synthesized by a facile, rapid and low-cost co-precipitation method, and served as anode material for liBs without any post-treatment. Sn-BDC exhibits a high reversible capacity with609/440 m Ah·g^(-1) at 50/2000 m A·g^(-1), and robust cycling stability of 856 m Ah·g^(-1) after 200 cycles at 200 m A·g^(-1),which are obviously superior to that of the Sn Ox/C counterparts. Moreover, an electrochemical reconstruction perspective on the lithium storage mechanism of Sn-BDC is proposed by systematic ex-situ characterizations. The reconstructed SnO_(2) replaces Sn-BDC and becomes the active material in the subsequent cycles. As the by-product of the lithiation reaction, the formed li-based metal-organic complex(li-BDC, wrapped around the reconstructed SnO_(2)) plays an important role in alleviating volume expansion and accelerating the charge transfer *** work is beneficial to design and construct the new electrode materials based on the electrochemical reconstruction for advanced liBs.

关键词： Electrochemical reconstruction Metal-organic complex Anode lithium storage mechanism lithium-ion batteries

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Genome assembly of autotetraploid Actinidia arguta highlights adaptive evolution and enables dissection of important economic traits

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Plant Communications 2024年第6期5卷 173-192页

作者： xue-Mei lu xiao-Fen Yu Guo-Qiang li ming-Hao Qu Huan wang Chuang liu Yu-Ping Man xiao-Han jiang Mu-Zi li Jian wang Qi-Qi Chen Rui Lei Cheng-Cheng Zhao Yun-Qiu Zhou Zheng-wang jiang Zuo-Zhou li Shang Zheng Chang Dong Bai-lin wang yan-Xiang Sun Hui-Qin Zhang Jie-Wei li Quan-Hui Mo Ying Zhang Xin Lou Hai-Xu Peng Ya-Ting Yi He-Xin wang Xiu-Jun Zhang Yi-Bo wang Dan wang li li Qiong Zhang Wen-Xia wang Yongbo liu Lei Gao jin-Hu Wu yan-Chang wang CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenChinese Academy of SciencesWuhanHubeiChina Key Laboratory of Western China’s Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhouGansuChina College of life Sciences University of Chinese Academy of SciencesBeijingChina Wuhan Frasergen Bioinformatics Co. LtdWuhanHubeiChina Institute of Soil and Fertilizer Anhui Academy of Agricultural SciencesHefeiChina College of Agricultural Sciences Xichang UniversityXichangSichuanChina Department of Horticulture Heilongjiang Academy of Agricultural SciencesHarbinHeilongjiangChina College of life Sciences Langfang Normal UniversityLangfangHebeiChina Institute of Horticulture Zhejiang Academy of Agricultural SciencesHangzhouZhejiangChina Guangxi Institute of Botany Chinese Academy of SciencesGuilinGuangxiChina Xi’an Botanical Garden of Shaanxi Province Institute of Botany of Shaanxi ProvinceXi’anShaanxiChina Institute of Modern Agricultural Research Dalian UniversityDalianLiaoningChina Bioinformatics Center College of Plant Science and TechnologyBeijing University of AgricultureBeijingChina College of Agriculture Eastern Liaoning UniversityDandongLiaoningChina Dalian Institute of Chemical Physics Chinese Academy of SciencesDalianLiaoningChina State Environmental Protection Key Laboratory of Regional Eco-process and Function Assessment Chinese Research Academy of Environmental SciencesBeijingChina Hubei Hongshan Laboratory WuhanHubeiChina The New Zealand Institute for Plant and Food Research limited AucklandNew Zealand

Actinidia arguta,the most widely distributed Actinidia species and the second cultivated species in the genus,can be distinguished from the currently cultivated Actinidia chinensis on the basis of its small and smooth fruit,rapid softening,and excellent cold *** evolution of tetraploid Actinidia species and the genetic basis of their important agronomic traits are still ***,we generated a chromosome-scale genome assembly of an autotetraploid male *** *** genome assembly was 2.77 Gb in length with a contig N50 of 9.97 Mb and was anchored onto 116 *** and clustering of 101 geographically representative accessions showed that they could be divided into two geographic groups,Southern and Northern,which first diverged 12.9 million years *** underwent two prominent expansions and one demographic bottleneck from the midPleistocene climate transition to the late *** genomics studies using paleoclimate data enabled us to discern the evolution of the species’adaptation to different historical *** genes(AaCEL1,AaPME1,and AaDOF1)related to flesh softening were identified by multi-omics analysis,and their ability to accelerate flesh softening was verified through transient expression assays.A set of genes that characteristically regulate sexual dimorphism located on the sex chromosome(Chr3)or autosomal chromosomes showed biased expression during stamen or carpel *** chromosome-level assembly of the autotetraploid *** genome and the genes related to important agronomic traits will facilitate future functional genomics research and improvement of ***.

关键词： kiwiberry dioecism adaptive evolution paleoclimate GEA rapid softening

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