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Red list assessments of Chinese higher plants

作者： Simmonds Monique S. J. Howes melanie-jayne Irving Jason

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International Journal of Digital Earth 2023年第1期16卷 2762-2775页

作者： Liping Li Haining Qin Eimear Nic Lughadha Yaomin Zheng Huawei Wan Jack Plummer melanie-jayne R.Howes Huiyuan Liu Yangming Jiang Tuo Wang Huihui Zhao Zhanfeng Shen Huiping Huang Chinese Academy of Sciences Aerospace Information Research InstituteBeijingPeople’s Republic of China Chinese Academy of Sciences Institute of BotanyBeijingPeople’s Republic of China Royal Botanic Gardens KewRichmondUK School of International Economics and Management Beijing Technology and Business UniversityBeijingPeople’s Republic of China. Satellite Environmental Application Center Ministry of Ecology and EnvironmentBeijingPeople’s Republic of China. University of Chinese Academy of Sciences BeijingPeople’s Republic of China

Based on the two most recent assessments of Chinese higher plants in 2013 and 2020,of 34,450 and 39,330 species,respectively,we analysed the threatened status of Chinese higher *** 2020,around 4,088(10.39%)of the assessed species in China are threatened,2,875(7.31%)Near Threatened,27,593(70.16%)not currently threatened and categorised as Least Concern and 4,752(12.08%)categorised as Data *** in 2013,3,767(10.93%)of the assessed higher plants in China are threatened,2,723(7.90%)Near Threatened,24,296(70.53%)Least Concern and 3,612(10.48%)Data *** of the Red List Index in the two years show different patterns when using different weighting methods with the equal steps weighting method showing a slight decrease(0.91675-0.91495)and the extinction risk weighting method showing a slight increase(0.98792-0.98797).We inferred that China's threatened plant species were likely/relatively effectively ***,attention should also be given to the non-threatened species in the future as an additional strategy for their conservation,to maintain their non-threatened status.

关键词： Chinese higher plants conservation IUCN red list assessment red list index(RLI) sustainable development goals(SDGs)

中美洲治疗糖尿病及其后遗症传统药用植物分析

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亚太传统医药 2017年第23期13卷 8-9页

作者： Peter Giovanninia melanie-jayne R.Howes Sarah E.Edwards 肯特大学

目前,全球有3亿8 700万人患有糖尿病,预计到2030年该病将成为全世界第七大死亡疾病。中美洲地区总发病率(8.5%)超过拉丁美洲大多数国家,且该地区广泛使用草药。通过调查中美洲的伯利兹、哥斯达黎加、萨尔瓦多、瓜地马拉、洪都拉斯、尼... 详细信息

目前,全球有3亿8 700万人患有糖尿病,预计到2030年该病将成为全世界第七大死亡疾病。中美洲地区总发病率(8.5%)超过拉丁美洲大多数国家,且该地区广泛使用草药。通过调查中美洲的伯利兹、哥斯达黎加、萨尔瓦多、瓜地马拉、洪都拉斯、尼加拉瓜和巴拿马等7个国家治疗糖尿病及其后遗症的传统药物使用情况,对中美洲传统草药治疗糖尿病及其后遗症研究进展进行综述,探讨可能解释其传统功效的科研成果。

关键词：糖尿病低血糖中美洲药用植物传统医学

Diterpenoids from Scutellaria barbata induce tumour-selective cytotoxicity by taking the brakes off apoptosis

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Medicinal Plant Biology 2022年第1期1卷 8-23页

作者： Matthew L.Tomlinson Man Zhao Elaine J.Barclay Jie Li Haixiu Li Juri Felix Lionel Hill Gerhard Saalbach Martin Rejzek Dongfeng Yang Qing Zhao Paul Kroon Wei Wang Yongping Bao melanie-jayne R.Howes Evangelos C.Tatsis Cathie Martin The John Innes Centre NorwichNR47UHUnited Kingdom College of Bioengineering and Biotechnology Zhejiang University of TechnologyHangzhou 310058China National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China Royal Botanic Gardens Kew RichmondSurreyLondon TW93ABUnited Kingdom College of Life Sciences Zhejiang Sci-Tech UniversityXiasha Higher Education ZoneHangzhou 310018China Shanghai Key Laboratory of Plant Functional Genomics and Resources Shanghai Chenshan Botanical GardenShanghai Chenshan Plant Science Research CenterChinese Academy of SciencesShanghai 201602China Quadram Institute Bioscience Norwich Research ParkNorwichNR47UAUnited Kingdom Norwich Medical School University of East AngliaNorwichNorfolkNR47TJUnited Kingdom CEPAMS:CAS-JIC Centre of Excellence in Plant and Microbial Sciences

Medicinal plants are an excellent source of structurally diverse,bio-active compounds with potential in the fight against *** of the most promising is Scutellaria barbata,prescribed traditionally for the treatment of *** A is the major diterpenoid,produced in specialized large,peltate trichomes on leaves of *** induces dose-dependent apoptosis,specifically in cancer *** major class of proteins down-regulated are pro-survival proteins,the Inhibitors of Apoptosis(IAPs),and IAP regulating *** propose that scutebarbatine A works by releasing the molecular brakes(the IAPs)on apoptosis in cell death-evading cancer *** between the cytotoxicity of methanolic extracts of *** leaves and decoctions(Ban Zhi Lian)prepared traditionally,showed substantially different chemical compositions and differential induction of *** suggest polyvalency between the constituents in both extracts,and ways to produce enhanced chemopreventive preparations for the treatment of cancer.

关键词： prescribed methanol structurally

Personalized medicine:Clinical oncology on molecular view of treatment

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World Journal of Clinical Oncology 2024年第8期15卷 992-1001页

作者： Rafick Costa Dos Santos Da Silva Nathalia de Andrade Simon AndréAlves Dos Santos Gabriel De Melo Olegário jayne Ferreira Da Silva Naide Oliveira Sousa Manuel Alvarez Troncoso Corbacho Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória Da Conquista 45029-094BahiaBrazil

Cancer,the second leading global cause of death,impacts both physically and *** treatments such as surgeries,chemotherapy,and radiotherapy have adverse effects,driving the need for more precise *** medicine enables more targeted *** mapping,alongside other molecular biology approaches,identifies specific genes,contributing to accurate *** review addresses,in clinical use,a molecular perspective on *** like alpha-fetoprotein,beta-human chorionic gonadotropin,5-hydroxyindoleacetic acid,programmed death-1,and cytotoxic T lymphocyte-associated protein 4 are explored,providing valuable ***,with an emphasis on artificial intelligence,revolutionizes the analysis of biological data,offering more accurate *** like liquid biopsy are emphasized for early *** medicine guides therapeutic strategies based on the molecular characteristics of the tumor,as evidenced in the molecular subtypes of breast *** allow personalized treatments,highlighting the role of trastuzumab and endocrine *** the benefits,challenges persist,including high costs,tumor heterogeneity,and ethical *** obstacles requires collaboration,ensuring that advances in molecular biology translate into accessible benefits for all.

关键词： Oncology Neoplasia Molecular biology Personalized medicine Molecular Markers Cancer

Biological soil crusts as an integral component of desert environments

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Ecological Processes 2013年第1期2卷 116-129页

作者： jayne Belnap Bettina Weber Department of Archaeology Simon Fraser UniversityBurnabyBC V5A 1S6Canada Department of Biology Plant Ecology and SystematicsUniversity of KaiserslauternP.O.Box 3049Kaiserslautern 67653Germany Multiphase Chemistry Department Max Planck Institute for ChemistryHahn-Meitner-Weg 1Mainz 55128Germany

The biology and ecology of biological soil crusts,a soil surface community of mosses,lichens,cyanobacteria,green algae,fungi,and bacteria,have only recently been a topic of *** efforts began in the western U.S.(Cameron,Harper,Rushforth,and ***),Australia(Rogers),and Israel(Friedmann,Evenari,and Lange)in the late 1960s and 1970s(e.g.,Friedmann et al.1967;Evenari 1985,reviewed in Harper and Marble 1988).However,these groups worked independently of each other and,in fact,were often not aware of each other’s *** addition,biological soil crust communities were seen as more a novelty than a critical component of dryland eco*** then,researchers have investigated many different aspects of these communities and have shown that although small to microscopic,biological soil crusts are critical in many ecological processes of *** often cover most of desert soil surfaces and substantially mediate inputs and outputs from desert soils(Belnap et al.2003).They can be a large source of biodiversity for deserts,as they can contain more species than the surrounding vascular plant community(Rosentreter 1986).These communities are important in reducing soil erosion and increasing soil fertility through the capture of dust and the fixation of atmospheric nitrogen and carbon into forms available to other life forms(Elbert et al.2012).

关键词： soil fertility component

Cost-effectiveness of lutetium(^177Lu)oxodotreotide vs everolimus in gastroenteropancreatic neuroendocrine tumors in Norway and Sweden

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World Journal of Clinical Cases 2020年第20期8卷 4793-4806页

作者： jayne Palmer Oscar R Leeuwenkamp Ossian Health Economics and Communications Basel 4051Switzerland Advanced Accelerator Applications Geneva 1204Switzerland

BACKGROUND Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)represent a relatively rare and heterogenous group of *** available treatment options for patients with progressive GEP-NETs include lutetium(177 Lu)oxodotreotide(177 LuDotatate)and everolimus[as well as sunitinib for patients with pancreatic NETs(P-NETs)].AIM To perform a health economic analysis to determine the cost-effectiveness of 177 LuDotatate compared with everolimus in patients with unresectable or metastatic midgut-NETs or P-NETs in both Sweden and *** Simulations were performed using a three-state partitioned survival model and analyses were performed separately for patients with midgut-NETs and *** input data were sourced from an indirect comparison that utilized survival data from clinical trials of 177 Lu-Dotatate and *** analyses were performed from the healthcare payer perspective over a time horizon of 20 *** Sweden,future costs and clinical outcomes were discounted at 3%per *** Norway,a discount rate of 4%per annum was *** For Sweden,improved survival outcomes and higher lifetime costs with 177 LuDotatate resulted in an incremental cost-effectiveness ratio(ICER)of SEK 391194 per quality-adjusted life year(QALY)gained for midgut NETs and SEK 16764 per QALY gained for P-NETs for 177 Lu-Dotatate compared with *** Norway,the corresponding ICERs were NOK 244444 per QALY gained and NOK 106451 per QALY gained,***-way sensitivity analyses revealed that the results were most sensitive to changes in drug acquisition costs and health state utility *** In both Sweden and Norway,from a healthcare provider perspective,177 LuDotatate is likely to be considered cost-effective relative to everolimus for the treatment of patients with unresectable or metastatic,progressive midgut-NETs or P-NETs.

关键词： Cost Cost-effectiveness Neuroendocrine tumors 177Lu-Dotatate Sweden Norway

Grasshoppers （Orthoptera： Acrididae） select vegetation patches in local-scale responses to foliar nitrogen but not phosphorus in native grassland

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Insect Science 2011年第5期18卷 533-540页

作者： Viviana Loaiza jayne L. Jonas Anthony Joern Division of Biology Kansas State University Manhattan Kansas USA

Key elements such as nitrogen （N） and phosphorus （P） are often limiting relative to the nutritional needs of herbivores that feed on them. While N often limits insect herbivores in natural terrestrial ecosystems, the effect of P is poorly studied in the field, even though compelling hypotheses from the ecological stoichiometry literature predict its importance. We evaluated small-scale spatial distributions of, and herbivory by, grasshoppers among neighboring plots that vary in foliar-N and -P in tallgrass prairie. Grasshopper densities were 67% greater in N-fertilized plots but detected no effect to grasshopper densities from P-fertilizer. Leaf damage to the dominant grass Andropogon gerardii was 32% greater in N-fertilized plots, but no response to foliar-P was detected. Herbivore damage to a common forb, goldenrod （Solidago missouriensis）, was not strongly linked by fertilizer treatments, although there was increased leaf damage in N-fertilizer treatments when no P was applied （a significant N ~ P interaction）. Under field conditions at local scales, we conclude that spatially heterogeneous distributions of grasshoppers are primarily affected by foliar-N in host plants with little evidence that P-levels contribute to the spatial patterns.

关键词： Andropogon gerardii ecological stoichiometry insect herbivory Konza Prairie N-P fertilization experiment Solidago rnissouriensis

Sequence-Independent Identification of Active LTR Retrotransposons in Arabidopsis

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Molecular Plant 2018年第3期11卷 508-511页

作者： jayne,Griffiths Marco,Catoni Mayumi,Iwasaki Jerzy,Paszkowski The Sainsbury Laboratory University of Cambridge Cambridge UK [∗]Corresponding author Present Address: University of Geneva Geneva Switzerland

Dear Editor,LTR retrotransposons （LTR-TEs） are mobile genetic elements that often comprise a large portion of the host genome and are particularly abundant in genomes of plants （Lisch, 2013）. They transpose through an RNA transcript that is reverse transcribed to an extrachromosomal DNA （ecDNA） of the original element that can insert at a new genomic location （Wicker et al., 2007）.

关键词： Arabidopsis LTR 鉴定人染色体 DNA RNA 元素植物

Operational effects of the UNOT gate on classical and quantum correlations

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Science Bulletin 2018年第12期63卷 765-770页

作者： Kuan Zhang Jiajun Ma Xiang Zhang jayne Thompson Vlatko Vedral Kihwan Kim Mile Gu Center for Quantum Information Institute for Interdisciplinary Informotion SciencesTsinghua UniversityBeijing 100084China Department of Atomic and Laser Physics.Clarendon Laboratory University of OxfordOxford OX1 3PUUK Department of Physics Renmin University of ChinaBeijing 100872China Centre for Quantum Technologies National University of SingaporeSingapore 117543Singapore Department of Physics Notional University of SingaporeSingapore 117551Singapore School of Mathematical and Physical Sciences Nanyang Technological UniversitySingapore 637371Singapore Complexity Institute Nanyang Technological UniversitySingapore 637335Singapore

The NOT gate that flips a classical bit is ubiquitous in classical information *** its quantum analogue,the universal NOT(UNOT) gate that flips a quantum spin in any alignment into its antipodal counterpart is strictly *** we explore the connection between this discrepancy and how UNOT gates affect classical and quantum *** show that while a UNOT gate always preserves classical correlations between two spins,it can non-locally increase or decrease their shared discord in ways that allow violation of the data processing *** experimentally illustrate this using a multi-level trapped ^(171)Yb^+ ion that allows simulation of anti-unitary operations.

关键词： Quantum information Universal NOT gate Quantum correlations Quantum discord Data processing inequality Embedding quantum simulation Ion trap