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Measurement and estimation of free field to eardrumtransfer function for virtual acoustic space research

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Chinese Journal of Acoustics 1997年第2期16卷 105-114页

作者： WU Zhenyang (Department of Radio Engineering, Southeast University Nanjing 210018)CHEN Jiashu and Richard A. Reale(Department of Neurophysiology, University of Wisconsin-madison)Received

Free field to Eardrum Thansfer Function (FETF) is one of the major factors influencing the identification of the sound source direction. FETF can be employed to generate a Virtual Acoustic Space (VAS) by computer and other equlpment. In this paper the methods to improve the measurement and estimation of FETF are approached. Least-mean-squares (LMS)method is much better than empirical FFT method. This paper also gives a sample description of excitation signals for measuring the impulse response of FETF.

关键词： Measurement and estimation of free field to eardrumtransfer function for virtual acoustic space research free

INFLUENCE OF THE ANTARCTIC SEA-ICE ON THE NORTH-WEST PACIFIC SUBTROPICAL HIGH AND ITS BACKGROUND OF OCEANATMOSPHERIC CIRCULATION

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Chinese Science Bulletin 1989年第17期34卷 1463-1465页

作者：彭公炳 PAO K.WANG Department of Climatology Institute of Geography Academia Sinica Beijing Department of Meteorology University of Wisconsin Madison U. S. A.

In view of the importance of the North-west Pacific subtropical high to weather-climate conditions in large areas of the Chinese territory, we have devoted our attention mainly to analyzing the relationship between the subtropical high and the Antarctic sea-ice. We have found that the high and the sea-ice are closely related to each other in our

关键词： Antarctic sea-ice subtropical high influence model

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缅甸传统民族医药治疗皮肤病经验概述

亚太传统医药 2021年第7期17卷 1-3页

作者： Myat Sanda Kyaw Min Min Aye madison Grinnell 缅甸仰光第二医科大学皮肤科缅甸仰光内布拉斯加大学医学院美国奥马哈

世界各地的人们饱受各种皮肤疾病的困扰,皮肤疾病有不同的症状、体征和并发症,包括感染、疼痛,以及由于皮损暴露于皮肤表面,导致心理上的羞耻感。现代医学和本国传统医药为皮肤病患者提供了许多治疗方案。塔纳卡(Thanaka)是一种原产于... 详细信息

世界各地的人们饱受各种皮肤疾病的困扰,皮肤疾病有不同的症状、体征和并发症,包括感染、疼痛,以及由于皮损暴露于皮肤表面,导致心理上的羞耻感。现代医学和本国传统医药为皮肤病患者提供了许多治疗方案。塔纳卡(Thanaka)是一种原产于缅甸的草药,可治疗多种皮肤疾病,在印度、斯里兰卡、爪哇和巴基斯坦等国家也有生产。对缅甸传统草药塔纳卡(Thanaka)在皮肤病治疗中的运用进行了概述。

关键词：皮肤病传统民族医药缅甸

New FT-Platform for Ultra-High Sensitivity Surface Plasmon Resonance （FT-SPR） Probing of Biomolecular Activities

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New FT-Platform for Ultra-High Sensitivity Surface Plasmon R...

Direct evidence of transformation from smectite to palygorskite:TEM investigation

第十四届全国分子光谱学术会议

作者： Jia Tang, Feng Gai, Eric Y Jiang Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA Thermo Electron Corporation, madison, WI 53711, USA

＜正＞Surface plasmon resonance （SFR） causes a reduction in the intensity of reflected light at a specific angle with respect to a conducting film surface. This angle varies with the refractive index close to the su... 详细信息

关键词： SPR FT-SPR Bio-sensor Biomolecular recognition Binding kinetics IgG-Anti IgG interaction

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Science China Earth Sciences 2004年第11期47卷 985-994页

作者： CHEN Tianhu1,,XU Huifang2,LU Anhuai3,XU Xiaochun1,PENG Shuchuan1 2 &YUE Shucang1 1.College of Resources and Environmental Engineering,Hefei University of Technology,Hefei 230009,China 2.Department of Geology and Geophysics,University of Wisconsin,madison,WI53706,USA 3.Department of Geology,Peking University,Beijing 100871,China Correspondence should be addressed to Chen Tianhu(email: tianhu@*** or cth168@***) College of Resources and Environmental Engineering Hefei University of Technology Hefei China Department of Geology and Geophysics University of Wisconsin Madison USA Department of Geology Peking University Beijing China

Palygorskite clays sampled from palygorskite clay deposits in Jiangsu and Anhui provinces were investigated by transmission electron microscopy (TEM). Many intergrowth phenomena of special ultra-microstructure between smectite and palygorskite were found. The ultra-microstructure indicates that palygorsite fiberrous crystals grow along (001) of primary smectite through structural transformation and decomposition of the primary smectite. According to field investigation and X-ray diffraction (XRD) analyses, the transformation mechanism and process can be described as: formation of smectite from basalt weathering deposited in localiza- tion basin; evaporation of lake water in aridity environment causing pH increase and concentra- tion of magnesium ion in interstice water of sediment smectite in the lake basin. Under alkaline conditions, magnesium ion occupied interlayer positions of the smectite. Because of the misfit between magnesium octahedral sheet and smectite layer, magnesium ion interaction with smec- tite layers caused the smectite to transform into palygorskite, and resulted in the formation of smectite and palygorskite complex particulates, and even smaller secondary smectite crystal plates. The transformation of smectite structure resulted in the formation of nanometer minerals with large specific surface area and excellent property of physics and chemistry in smec- tite-palygorskite mixing clay. The results from TEM investigation are important for understanding properties of palygorskite clay and application.

关键词： palygorskite, smectite, transmission electron microscopy, X-ray diffraction, nanometer mineralogy.

Delivering an mRNA vaccine using a lymphatic drug delivery device improves humoral and cellular immunity against SARS-CoV-2

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Journal of Molecular Cell Biology 2022年第6期14卷 47-56页

作者： Runqiang Chen Hui Xie Sahba Khorsandzadeh madison Smith Namir Shaabani Qidong Hu Xiaoxuan Lyu Hua Wang Wan-lin Lim Haotian Sun Henry Ji Brian Cooley Russell Ross David M.Francis Sorrento Therapeutics Inc.San DiegoCA 92121USA Sofusa a Division of Sorrento TherapeuticsAtlantaGA 30350USA

The exploration and identification of safe and effective vaccines for the SARS-CoV-2 pandemic have captured the world's attention and remains an ongoing issue due to concerns of balancing protection against emerging variants of concern while also generating long-lasting immunity. Here, we report the synthesis of a novel messenger ribonucleic acid encoding the spike protein in a lipid nanoparticle formulation (STI-7264) that generates robust humoral and cellular immunity following immunization of C57Bl6 mice. In an effort to improve immunity, a clinically focused lymphatic drug delivery device (MuVaxx) was engineered to modulate immune cells at the injection site (epidermis and dermis) and draining lymph node (LN) and tested to measure adaptive immunity. Using MuVaxx, immune responses were elicited and maintained at a 10-fold dose reduction compared to traditional intramuscular (IM) administration as measured by anti-spike antibodies, cytokine-producing CD8 T cells, neutralizing antibodies against the Washington (wild type) strain and South African (Beta) variants, and LN-resident spike-specific memory B cells. Remarkably, a 4-fold-elevated T cell response was observed in MuVaxx-administered vaccination compared to that of IM-administered vaccination. Thus, these data support further investigation into STI-7264 and lymphatic-mediated delivery using MuVaxx for SARS-CoV-2 and VoC vaccines.

关键词： COVID-19 lymph nodes lymphatics vaccines drug delivery

RECONSTRUCTION OF THE EIGHTEENTH CENTURY SUMMER MONTHLY PRECIPITATION SERIES OF NANJING,SUZHOU,AND HANGZHOU USING THE CLEAR AND RAIN RECORDS OF QING DYNASTY”

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Acta meteorologica Sinica 1989年第3期3卷 261-278页

作者：张德二 Academy of Meteorological Science State Meteorological Administration Beijing

In this study the Qing weather records 'Clear and Rain Records' were used to reconstruct the 18th century summer (June-August) precipitation and monthly precipitation series of May, June, July, and August. The nature of these records and the techniquc of transforming them into numerical codes are described. The procedure of converting these descriptive records into quantitative monthly precipitation and its scientific basis are given in detail. The reliability of the obtaind precipitation series is also ex- amined.

关键词： RECONSTRUCTION OF THE EIGHTEENTH CENTURY SUMMER MONTHLY PRECIPITATION SERIES OF NANJING SUZHOU AND HANGZHOU USING THE CLEAR AND RAIN RECORDS OF QING DYNASTY

Simulation of 3D moving sound

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Chinese Journal of Acoustics 1999年第2期18卷 146-151页

作者： QIU Yujing Jenison R L Hu Y H Reate R A Brugge J F (Departments of Electrical and Computer Engineering, Psychology, Physiology and Waisman Center, University of Wisconsin-madison USA WI 53705)

A novel approach to the simulation of 3D sound movement by combining wellknown physical and biophysical cues into a discrete synthesis system is introduced. Physical cues include both the dependence of intensity on distance from the sound source and the Doppler effect. Biophysical features include the direction-dependent transfer functions imposed by a listener's head and ears and interaural time cues. Our technique requires very little disk storage since it relies on Iow-dimensional functional models that relate cue values to arbitrary locations in a virtual space. The system has been implemented on a modern workstation and can synthesize in quasi-real-time movements of arbitrary sound sources and trajectories that are delivered over earphones

关键词： Simulation of 3D moving sound Chen Virtual HRTF

Conceptual model about the interaction between El Nio/ Southern Oscillation and Quasi-Biennial Oscillation in far west equatorial Pacific

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Science China Earth Sciences 2006年第8期49卷 889-896页

作者： LIU Qinyu1, LIU Zhengyu2,1 & PAN Aijun 1,3 1. Physical Oceanography Lab. & Atmosphere-Ocean Interaction and Climate Lab., Ocean University of China, Qingdao 266003, China 2. Center for Climate Research, University of Wisconsin-madison, madison, WI 53706-1695, USA 3. Environment and Dynamics Lab., Third Institute of Oceanography, Xiamen 361005, China

Interaction between the Quasi-Biennial Oscillation in far west equatorialPacific (QBOWP) and the El Nino/Southern Oscillation (ENSO) is studied using a new conceptual *** this conceptual model, the QBOWP effects on ENSO are achieved through two ways: (1) the oceanicKelvin wave along equatorial Pacific, and (2) the Atmospheric Walker Circulation anomaly, while ENSOeffects on QBOWP can be accomplished by the atmospheric Walker Circulation anomaly. Diagnosisanalysis of the model results shows that the Atmospheric bridge (Walker circulation) plays a moreimportant role in interaction between the ENSO and QBOWP than the oceanic bridge (oceanic Kelvinwave along equatorial Pacific); It is found that by the interaction of the ENSO and QBOWP, a freeENSO oscillation with 3-5 years period could be substituted by a oscillation with the quasi-biennialperiod, and the dominant period of SST anomaly and wind anomaly in the far west equatorial Pacifictends to be prolonged with enhanced ENSO forcing. Generally, the multi-period variability in thecoupled Atmosphere-Ocean System in the Tropical Pacific can be achieved through the interactionbetween ENSO and QBOWP.

关键词： El nino/southern oscillation quasi-biennial oscillation interaction coupled system kelvin wave walker circulation