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国外畜牧科技 2002年第1期29卷 52-52页

作者： hans-christian.张龙现

猪等孢球虫感染引起的球虫病,通常发生于8～15日龄的仔猪.对该病的研究结果表明仔猪球虫病的流行比人们想象的要常见得多.

关键词：仔猪球虫病流行性危害

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两例食管癌肉瘤克隆来源的分子生物学分析

中华病理学杂志 2001年第5期30卷 366-366页

作者：孙孟红朱雄增 Peter Moeller christian.Herfarth Magnus von Knebel Doeberitz hans K Schackert Thomas Lehnert Johannes Gebert 复旦大学附属肿瘤医院病理科分子病理研究室 Division of Molecular Diagnostic and Therapy University Heidelberg INF 110 69120 Heidelberg Germany

一、材料、方法和结果1.临床病理情况:例1男,56岁.肉眼可见食管中段外生性10.0 cm×4.5 cm肿块,灶性褐色浅表溃疡.切面灰白.组织学见分化差非角化鳞状细胞巢及纤维肉瘤成分混合存在.两种瘤细胞成分均有丰富的核分裂象.分期pT2NOM0,分级... 详细信息

一、材料、方法和结果1.临床病理情况:例1男,56岁.肉眼可见食管中段外生性10.0 cm×4.5 cm肿块,灶性褐色浅表溃疡.切面灰白.组织学见分化差非角化鳞状细胞巢及纤维肉瘤成分混合存在.两种瘤细胞成分均有丰富的核分裂象.分期pT2NOM0,分级Ⅲ.患者术后5个月死于复发.例2男,59岁.食管中1/3段6.6 cm×3.5 cm×2.6 cm息肉状肿块,表面灶性溃疡.切面灰白色,灶性红色.组织学见不同分化程度的鳞状细胞癌.另见网格状分布的基底细胞样癌成分.以上两种成分之间,纤维肉瘤细胞散在分布.分期pT3NOM0,分级Ⅰ～Ⅳ.术后10个月死于肿瘤复发.

关键词：食管癌肉瘤克隆来源分子生物学

Heterotic patterns in rapeseed (Brassica napus L.) using exotic germplasm for Chinese semi-winter hybrid breeding

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Engineering Sciences 2013年第5期11卷 41-44,50页

作者： Qian Lunwen Chen Lunlin Mei Jiaqin Li Maoteng Martin Frauen christian.Jung Qian Wei Meng Jinling College of Agronomy and Biotechnology Southwest University National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural University Institute of Crop Science Jiangxi Academy of Agricultural Sciences School of Life Science and Technology Huazhong University of Science and Technology Norddeutsche Pflanzenzucht hans-Georg Lembke KG Plant Breeding Institute Christian-Albrechts-University of Kiel

Chinese semi-winter rapeseed,genetically differing from winter and spring rapeseed,has been considered to possess strong potential as parent in winter and spring rapeseed hybrid breeding programs. However,no detailed researches have been documented whether winter and spring rapeseed lines have potential for Chinese semiwinter rapeseed hybrid breeding. The objectives of this study are to estimate the potential of winter and spring rapeseed for semi-winter rapeseed hybrid breeding,and to investigate the association of general combining ability(GCA) with adaptation of parental lines by combining with the data in our previous studies. Four winter and four spring male sterile lines were crossed with 14 Chinese semi-winter rapeseed lines to develop 112 hybrids,which were evaluated together with their parents for seed yield under three environments in China. The exotic parental lines were not adapted to local environment as demonstrated by late flowering,low seed weight and poor seed yield per se. However,the hybrids,especially derived from winter rapeseed exhibited strong heterosis for seed yield,indicating that winter rapeseed germplasm has a great potential for rapeseed hybrid breeding in China. Our data suggested a strong association of GCA with their adaptation ability of parental lines,since high to middle correlations were found for local parental lines and low correlations for exotic parental lines under spring,winter and semi-winter eco-growth environments. The hybrid breeding program using exotic germplasm in rapeseed was discussed.

关键词： eco-growth environment GCA heterotic pattem rapeseed

精神对于自然“绝对地不感恩”——黑格尔“人类学”中的逻辑规定、肉体性、动物磁力以及疯狂

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伦理学术 2020年第2期9卷 -页

作者： [德]汉斯克里斯蒂安·卢卡斯张有民(译) 不详复旦大学

黑格尔的"人类学"处理的是精神与自然的关系问题,为此它详细描述了精神与自然相分离的过程,并把这种关系描述为前者对于产生它的自然的"不感恩"。"人类学"在根本上依赖于"逻辑学"且与其中诸范畴的发展进程相一致。"自然灵魂"论述的是在... 详细信息

黑格尔的"人类学"处理的是精神与自然的关系问题,为此它详细描述了精神与自然相分离的过程,并把这种关系描述为前者对于产生它的自然的"不感恩"。"人类学"在根本上依赖于"逻辑学"且与其中诸范畴的发展进程相一致。"自然灵魂"论述的是在自然方面受到限制的人的生命,按照"普遍性、特殊性、个体性"的模型展开。在"感觉灵魂"中,"病"基于"逻辑学"中的"质"这一范畴被规定为不适宜性,从而守护神、动物磁力、疯狂等诸多现象能够根据该规定被统摄起来。在"习惯"和"现实灵魂"中,黑格尔在三个版本的《哲学全书》对它们进行了不同乃至自相矛盾的规定。这一事实说明他在此遭遇到了一系列他本人最终没有妥善解决的困境。他在这些问题上的失败进而说明:他的"人类学"并未彻底完成从自然过渡到精神、必然性过渡到自由的论证目标。

关键词：黑格尔人类学精神灵魂肉体性动物磁力疯狂

Heart‘omicsin’AGEing (HOMAGE):design,research objectives and characteristics of the common database

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The Journal of Biomedical Research 2014年第5期28卷 349-359页

作者： Lotte Jacobs Lutgarde Thijs Yu Jin Faiez Zannad Alexandre Mebazaa Philippe Rouet Florence Pinet Christophe Bauters Burkert Pieske Andreas Tomaschitz Mamas Mamas Javier Diez Kenneth McDonald John G F Cleland hans-Peter Brunner-La Rocca Stephane Heymans Roberto Latini Serge Masson Peter Sever christian.Delles Stuart Pocock Timothy Collier Tatiana Kuznetsova Jan A Staessen Studies Coordinating Centre Research Unit Hypertension and Cardiovascular EpidemiologyKU Leuven Department of Cardiovascular Sciences University of Leuven Centre d'Investigation Clinique Pierre Drouin and U 961 Hypertension and Heart Failure UnitInstitut Lourrain du Coeur etdes VaisseauxInsermNancyFrance Department of Anesthesiology and Critical Care Medicine InsermUMR-S942Hopital LariboisiereUniversite Paris Diderot Equipe obesite et insuffisance cardiaque Universite UPSInserm I2MCUMR 1048ToulouseFrance Inserm U744CHRULilleFrance Department of Cardiology Medical University Graz Cardiovascular Institute University of ManchesterManchesterUK Division of Cardiovascular Sciences Foundation for Applied Medical ResearchUniversity of Navarra Heart Failure Unit St Vincent's University Hospital University College Dublin Department of Cardiology University of HullUK Department of Cardiology Maastricht University Medical CentreNetherlands Center for Heart Failure Research Department of CardiologyMaastricht UniversityNetherlands Department of Cardiovascular Research IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri" International Center for Circulatory Health Imperial College Institute of Cardiovascular and Medical Sciences BHF Glasgow Cardiovascular Research CenterUniversity of Glasgow London School of Hygiene and Tropical Medicine

Heart failure is common in older people and its prevalence is *** Heart ＇omics＇ in AGEing（HOMAGE） project aims to provide a biomarker approach that will improve the early diagnosis of heart failure.A large clinical database,based on（1） prospective population studies or（2） cross-sectional,prospective studies or randomized controlled trials（RCTs） of patients at risk for or with overt cardiovascular disease will be constructed to determine most promising ＇omics＇-based biomarkers to identify the risk of developing heart failure and/or *** studies,patient cohorts and RCTs are eligible for inclusion in the common database,if they received ethical approval to obtain and share data and have baseline information on cardiovascular risk ***,the HOMAGE database includes 43,065 subjects,from 20 studies in eight European countries,including healthy subjects from three population studies in France,Belgium and Italy（n = 7,124）,patients with heart failure（n = 4,312） from four cohorts in the UK,Spain and Switzerland and patients at high risk for cardiovascular disease（n = 31,629） in 13 *** is anticipated that more partners will join the consortium and enlarge the pooled *** large merged database will be a useful resource with which to identify candidate biomarkers that play a role in the mechanism underlying the onset and progression of heart failure.

关键词： left ventricle heart failure heart failure with reduced ejection fraction heart failure with preserved ejection fraction population science morbidity mortality

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量子悖论只是想象？

环球科学 2013年第7期 66-71页

作者：汉斯·克里斯蒂安·冯贝耶尔(hans christian.von Baeyer) 阳曦(翻译)

新版本的量子理论将微观世界里的种种奇怪悖论一扫而空。但是也要付出代价，按照新理论，量子信息只不过是存在于想象中的东西。

关键词：量子理论想象悖论微观世界量子信息

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跨文化分析的人类发展理论

开放时代 2012年第1期 80-108页

作者：克里斯蒂·韦尔泽(christian.Welzel) 罗纳德·英格哈特(Ronald Inglehard) 汉斯-迪特尔·克林曼(hans-Dieter Klingemann) 沈杰(译) 王正绪(译) 德国不莱梅雅克布斯大学美国密歇根大学德国柏林社会科学研究中心不详

本文阐述社会经济发展、个人解放取向的文化变迁、民主化三个过程所构成的社会进步的一种连聚合性的症候群。这样一种症候群,其共同焦点是不能由经典现代化理论所恰当地说明的。我们把这一症候群解释为"人类发展",意在表明,它的三个构... 详细信息

本文阐述社会经济发展、个人解放取向的文化变迁、民主化三个过程所构成的社会进步的一种连聚合性的症候群。这样一种症候群,其共同焦点是不能由经典现代化理论所恰当地说明的。我们把这一症候群解释为"人类发展",意在表明,它的三个构成要素拥有一个共同焦点,即在于拓宽人类的选择。社会经济发展通过增加个人的资源,赋予人类以选择的客观手段;不断增长的解放取向的价值观强化了人们对于选择的主观定向而民主化则通过制度化的自由权利提供了选择的合法化保证。对"世界价值观调查"数据的分析表明,个体资源、解放取向的价值观、自由权利之间的联系在跨国家、跨地区和跨文化区域之间是普遍存在的;这种人类发展的症候群是被一种个体资源和对于自由权利的解放取向的价值观的因果效应所塑造的;而这种效应是通过它对于精英的品质的影响力而起作用的,因为这种因素使自由权利变得更有效。

关键词：人类发展民主化解放价值自我表达价值世界价值观念调查

Multi-scale phylogenetic structure in coastal dune plant communities across the globe

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Journal of Plant Ecology 2014年第2期7卷 101-114页

作者： Ane Kirstine Brunbjerg Jeannine Cavender-Bares Wolf L.Eiserhardt Rasmus Ejrnæs Lonnie W.Aarssen Hannah L.Buckley Estelle Forey Florian Jansen Jens Kattge Cynthia Lane Roy A.Lubke Angela T.Moles Ana Laura Monserrat Robert K.Peet Julissa Roncal Louise Wootton Jens-christian.Svenning Ecoinformatics&Biodiversity Group Department of BioscienceAarhus UniversityNy Munkegade 114DK-8000 Aarhus C.Denmark Department of Bioscience Aarhus UniversityGrenaavej 14DK-8410 RøndeDenmark Department of Ecology Evolution and BehaviorUniversity of Minnesota1987 Upper Buford CircleFalcon HeightsMN 55108USA Department of Biology Queens University116 Barrie StreetKingstonOntario K7L 3N6Canada Department of Ecology Lincoln UniversityPO Box 84Canterbury 7647New Zealand Laboratoire d’Ecologie EA 1293 ECODIVFED SCALEUFR Sciences et TechniquesUniversitéde Rouen76821 Mont Saint Aignan CedexFrance Institute of Botany and Landscape Ecology Soldmannstr.1517487 GreifswaldGermany Functional Biogeography Research Group Max Planck Institute for BiogeochemistryHans Knoell Str.1007745 JenaThuringiaGermany Lake Lily Ecology Ltd.PO Box 8455CanmoreAB T1W 2V2Canada Department of Botany Rhodes UniversityPO Box 94GrahamstownEast Cape 6140South Africa Evolution&Ecology Research Centre School of BiologicalEarth and Environmental SciencesThe University of New South WalesBotany RoadKensingtonSydneyNew South Wales 2034Australia Grupo de Investigación en Sistemas Ambientales Complejos Facultad de IngenieríaUniversidad de FloresPedernera 275Ciudad de Buenos AiresArgentina Department of Biology University of North CarolinaChapel HillNC 27599-3280USA Department of Biology Memorial University of Newfoundland232 Elizabeth AvenueSt.John'sNL A1B 3X9Canada Department of Biology Georgian Court University900 Lakewood AvenueLakewoodNJ 08701USA

Aims Studies integrating phylogenetic history and large-scale community assembly are few,and many questions remain ***,we use a global coastal dune plant data set to uncover the important factors in community assembly across scales from the local filtering processes to the global long-term diversification and dispersal *** dune plant communities occur worldwide under a wide range of climatic and geologic conditions as well as in all biogeographic ***,global patterns in the phylogenetic composition of coastal dune plant communities have not previously been *** The data set comprised vegetation data from 18463 plots in New Zealand,South Africa,South America,North America and *** phylogenetic tree comprised 2241 plant species from 149 *** calculated phylogenetic clustering(Net Relatedness Index,NRI,and Nearest Taxon Index,NTI)of regional dune floras to estimate the amount of in situ diversification relative to the global dune species pool and evaluated the relative importance of land and climate barriers for these diversification patterns by geographic analyses of phylogenetic *** then tested whether dune plant communities exhibit similar patterns of phylogenetic structure within ***,we calculated NRI for local communities relative to the regional species pool and tested for an association with functional traits(plant height and seed mass)thought to vary along sea–inland *** Findings Regional species pools were phylogenetically clustered relative to the global pool,indicating regional *** showed stronger clustering than NRI pointing to the importance of especially recent diversifications within *** species pools grouped phylogenetically into two clusters on either side of the tropics suggesting greater dispersal rates within hemispheres than between *** NRI plot values confirmed that most communities were also phylogenetically clus

关键词： disturbance phylogenetic community structure plant functional traits plant height seed mass

Bacteriological Profile, Antimicrobial Susceptibility Patterns and Predictors of Bacteremia in Neonates with Clinical Sepsis at KCMC Hospital, Northern Tanzania

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Open Journal of Epidemiology 2024年第4期14卷 647-668页

作者： Nyemo P. Kwanga Aisa Shayo Rune Philemon Arnold Likiliwike Mselle Mathew Elise Kimambo Phillip Mrindoko Grace Kinabo Levina Msuya hans Maro Raimos Olomi Department of Pediatrics and Child Health Kilimanjaro Christian Medical University College Moshi Tanzania Department of Pediatrics and Child Health Kilimanjaro Christian Medical Centre Moshi Tanzania UNICEF Tanzania Dar es Salaam Tanzania

Background: Despite a significant decline in neonatal deaths in the last 20 years (5 million in 1990 to 2.4 million in 2019), the risk of death is still high, especially in developing countries. In Tanzania, neonatal sepsis is the third leading cause of neonatal death, accounting for 25% of all deaths. The rising global threat of antimicrobial resistance and the rising burden of neonatal death due to neonatal sepsis have been of great concern and have delayed progress toward reaching SDG goal 3.2 by 2030. This study aims to determine the bacteriological profile, antibiotic susceptibility patterns, and predictors of bacteremia among neonates with clinical sepsis at KCMC Hospital in Northern Tanzania. Methodology: This study had a cross-sectional design conducted at KCMC Hospital, Northern Tanzania. The study population was neonates admitted to the neonatal unit at KCMC Hospital. Data were collected using questionnaires and blood cultures from neonates. Frequencies and proportions were used to summarize categorical variables, while continuous variables were summarized using mean and standard deviation. The frequencies and proportions of bacteria isolated and the antimicrobial susceptibility results were analyzed and compared using Pearson’s chi-square test and Fisher’s exact test where applicable. Modified Poisson regression model was used to determine factors associated with positive blood culture. Results: Out of 411 neonates with a clinical diagnosis of neonatal sepsis, 175 (42.9%) had positive blood cultures. Gram-positive bacteria were most frequently isolated at 52.3%, and gram-negative bacteria were 47.7%. Coagulase-negative Staphylococcus (30.7%) and Staphylococcus aureus (19.9%) were the predominant gram-positive isolates. Gram-negative isolates were Klebsiella spp 47 (26.7%), E. coli 10 (5.7%), and Citrobacter spp 10 (5.1%). The gram-positive isolates were sensitive to vancomycin, piperacillin/tazobactam, and ceftazidime, whereas the gram-negative were sensi

关键词： Bacteriological Profile Antimicrobial Susceptibility Patterns Clinical Sepsis Neonates

Interdisciplinary management of central nervous system metastasis and neoplastic meningitis:recent developments and future perspectives

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Journal of Cancer Metastasis and Treatment 2016年第1期2卷 163-175页

作者： Ghazaleh Tabatabai Marilin Koch Cristiana Roggia Juliane Ebert Claus Garbe Friedegund Meier Sara Brucker Eva Maria Grischke Diethelm Wallwiener Robert Möhle Lothar Kanz Walter Erich Aulitzky Ulrike Ernemann christian.laFougere Konstantin Nikolaou Bernd Pichler Jens Schittenhelm Manuela Neumann Falko Fend Stefan Czemmel Sven Nahnsen Frank Paulsen Daniel Zips Maike van Lessen hans-Otto Karnath Ulf Ziemann Constantin Roder Marco Skardelly Jürgen Bernd Honegger Marcos Tatagiba Interdisciplinary Division of Neuro-Oncology Departments of Vascular Neurology and NeurosurgeryUniversity Hospital TübingenHertie Institute for Clinical Brain ResearchEberhard Karls University72076 TübingenGermany Division of Dermato-Oncology Department of DermatologyUniversity Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Gynecology and Ostetrics University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Internal Medicine(II) University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Hematology and Oncology Robert Bosch Hospital StuttgartStuttgartGermanyComprehensive Cancer CenterTübingen StuttgartGermany Department of Diagnostic and Interventional Neuroradiology University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Nuclear Medicine University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Diagnostic and Interventional Radiology University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Preclinical Imaging and Radiopharmacy University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Pathology and Neuropathology University Hospital TübingenEberhard Karls University72076 TübingenGermany Department of Radiation Oncology University Hospital TübingenEberhard Karls University72076 TübingenGermany Division of Neuropsychology University Hospital TübingenHertie Institute for Clinical Brain ResearchEberhard Karls University72076 TübingenGermany Center for CNS tumors Comprehensive Cancer Center Tübingen StuttgartGermany Center for Personalized Medicine University Hospital TübingenEberhard Karls UniversityTübingenGermany Center for Dermato-Oncology University Hospital DresdenGermany Quantitative Biology Center(QBiC) Eberhard Karls UniversityTübingenGermany DKTK DKFZ partner site Tübingen.18Department of ImmunologyEberhard Karls University TübingenGermany

The incidence of metastatic disease in the central nervous system(CNS)is *** to current estimates,up to a third of adult cancer patients will suffer from CNS *** evidence-based data from prospective randomized trials are rare,however,because CNS metastasis patients were often excluded from clinical trial *** management of CNS metastasis patients is therefore rather ill-defined and an interdisciplinary *** basic and translational science data have begun contributing to a more profound understanding of the molecular mechanisms leading to invasion of tumor cells into the *** report reviews advances,challenges,and perspectives in this field.

关键词： Brain tumor central nervous system metastases interdisciplinary management