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Severe acute respiratory syndrome-coronavirus-2(SArS-COV-2)infection of pneumocytes with vaccination and drug therapy:Mathematical analysis and optimal control

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International Journal of Biomathematics 2024年第2期17卷 299-334页

作者： r.Viriyapong p.Inkhao Department of Mathematics Faculty of Science Naresuan University Phitsanulok65000Thailand

We propose a mathematical model studying a within-host infection dynamics of SArSCoV-2 in *** model incorporates immune response,vaccination and antiviral *** crucial properties of the model-the existence,positivity and boundary of solutions are *** points and the basic reproduction number are *** stability of each equilibrium point is *** control is applied to the model by adding three control variables:vaccination,treatment by Favipiravir and treatment by *** results show that each individual control could reduce SArS-CoV-2 infection in some aspects;however,with a combination of three controls,we obtain the best results in reducing SArS-CoV-2 *** study has emphasized the importance of prevention by vaccine and the antiviral treatments.

关键词： SArS-CoV-2 vaccination drug therapy immune response optimal control

Temperature-dependent thermal conductivity and fuel performance of UN-UO_(2) and UN-X-UO_(2)(X=Mo,W)composite nuclear fuels by finite element modeling

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Journal of Materiomics 2024年第4期10卷 937-946页

作者： Faris Sweidan Diogo ribeiro Costa Huan Liu pär Olsson KTH royal Institute of Technology Nuclear EngineeringStockholm10691Sweden Westinghouse Electric Sweden AB Västerås72163Sweden

The temperature-dependent effective thermal conductivity of UN-X-UO_(2)(X=Mo,W)nuclear fuel composite was *** the experimental design,the thermal conductivity was calculated using Finite Element Modeling(FEM),and compared with analytical models for 10%,30%,50%,and 70%(in mass)uncoated/coated UN microspheres in a UO2 *** FEM results show an increase in the fuel thermal conductivity as the mass fraction of the UN microspheres increases from 1.2 to 4.6 times the UO2 reference at 2,000 *** results from analytical models agree with the thermal conductivity estimated by *** results also show that Mo and W coatings have similar thermal behaviors,and the coating thickness influences the thermal conductivity of the *** higher weight fractions,the thermal conductivity of the fuel composite at room temperature is substantially influenced by the high thermal conductivity coatings approaching that of ***,the thermal conductivity from FEM was used in the fuel thermal performance evaluation during LWr normal operation to calculate the maximum centerline *** results show a significant decrease in the fuel maximum centerline temperature ranging from−94 K for 10% UN to−414 K for 70%(in mass)UN compared to UO2 under the same operating conditions.

关键词： Accident tolerant fuel UN-X-UO_(2) Composite nuclear fuel Thermal conductivity Finite element modeling Thermal performance

C19MC mirNA-520G induces Sp100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma

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Genes & Diseases 2024年第1期11卷 60-63页

作者： Goodwin G.Jinesh Marian T.Smallin Nino Mtchedlidze Isha Godwin Marco Napoli Nicole Hackel Manali S.phadke Avani A.Deshpande Xiaobo Li John H.Lockhart Jaden r.Baldwin Suehelay Acevedo-Acevedo Yifeng Gao Michelle A.reiser Keiran S.M.Smalley Elsa r.Flores Andrew S.Brohl Department of Molecular Oncology H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Molecular Medicine program H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Saveetha Medical College ChennaiTamil Nadu 602105India Tumor Biology Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Sarcoma Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA

Sp100 is an antiviral protein that restricts the productive stage of human papillomavirus(HpV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of Sp100 and promotes its degradation(Table S1).Interferon(IFN)signaling could still produce more Sp100 through transcription to counteract viruses.1 Viruses also disable the transcriptional up-regulation of Sp100 to achieve persistent infection in hosts.

关键词： Sp100 melanoma stabilization

Stability Analysis of DC Microgrid Clusters Based on Step-by-step System Matrix Building Algorithm

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Journal of Modern power Systems and Clean Energy 2024年第3期12卷 900-912页

作者： K.Jithin N.Mayadevi r.Hari Kumar V.p.Mini the Department of Electrical Engineering College of Engineering TrivandrumAPJ Abdul Kalam Technological University(APJAKTU)ThiruvananthapuramIndia

DC microgrids(DCMGs)are made up of a network of sources and loads that are connected by a number of power electronic converters(pECs).The increase in the number of these pECs instigates major concerns in system *** interconnecting the microgrids to form a cluster,the system stability must be *** paper proposes a novel stepby-step system matrix building(SMB)algorithm to update the system matrix of an existing DCMG cluster when a new microgrid is added to the cluster through a distribution *** stability of the individual DCMGs and the DCMG cluster is analyzed using the eigenvalue ***,the particle swarm optimization(pSO)algorithm is used to retune the controller gains if the newly formed cluster is not *** simulation of the DCMG cluster is carried out in MATLAB/Simulink environment to test the proposed *** results are also validated using the Op4510 real-time simulator(rTS).

关键词： Converter DC microgrid cluster eigenvalue interconnection particle swarm optimization system stability system matrix

Convergent plate boundary environments for formation of≥3800 Ma mafic-ultramafic assemblages(Isua area,Greenland):Implications for early global geodynamics

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Geoscience Frontiers 2024年第3期15卷 119-136页

作者： Allen p.Nutman Clark r.L.Friend Vickie C.Bennett School of Earth Atmospheric and Life SciencesUniversity of WollongongWollongongNSW 2522Australia Glendale TiddingtonOxon OX92LQUK research School of Earth Sciences Australian National UniversityCanberraACT 2601Australia

In the gneiss terrane on the south side of the Eoarchean Isua supracrustal belt,ultramafic rocks with relict abyssal peridotite mineralogy(Bennett et al.,2002;Friend et al.,2002;Nutman et al.,2007;rollinson,2007;van de Löcht et al.,2020),layered gabbros with cumulate ultramafic rocks,basalts and associated siliceous sedimentary rocks were tectonically-imbricated,prior to and during intrusion of ca.3800 Ma *** with3800 Ma basalts in the Outer Arc Group of the nearby Isua supracrustal belt,the composition of all these mafic rocks(e.g.,Th-Hf-Nb systematics,high Th/Yb,Ba/Nb,Ba/Yb ratios and negative Nb and Ti anomalies)shows affinity with modern suprasubduction rocks whose genesis involved fluid fluxing of the upper ***,the majority of these samples have Ba/Nb and Ba/Yb values less than in modern island arc magmas,but similar to many backarc basin magmas(e.g.,pearce and Stern,2006).It is unknown whether these ca.3800 Ma mafic rocks are,(i)arc rocks where the Ba/Nb and Ba/Yb signatures reflect lower surficial Ba in Eoarchean oceanic settings,or(ii)in direct comparison with phanerozoic suites,these signatures reflect a back-arc setting with interplay between fluid fluxing and decompressional *** tectonic intercalation of upper mantle with lower and upper crustal rocks,combined with the fluid-fluxing influences seen in chemistry of all the mafic rocks is best accommodated in a compressional Eoarchean convergent plate boundary setting within a mobile-lid *** stagnant lid scenarios of crust formation,if operative,must have co-existed or alternated with mobile-lid regimes by 3800 Ma.

关键词： Eoarchean Fluid-fluxing plate tectonics Suprasubduction Crustal evolution

reinforced tissue matrix to strengthen the abdominal wall following reversal of temporary ostomies or to treat incisional hernias

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 823-832页

作者： Spencer p Lake Corey r Deeken Amit K Agarwal Mechanical Engineering&Materials Science Washington University in St.LouisSt.LouisMO 63130United States Covalent Bio LLCSt.LouisMO 63025United States Department of Surgery McGovern Medical School at UTHealthHoustonTX 77026United States

BACKGrOUND Abdominal wall deficiencies or weakness are a common complication of tem-porary ostomies,and incisional hernias frequently develop after colostomy or ileostomy *** use of synthetic meshes to reinforce the abdominal wall has reduced hernia *** meshes have also been used to enhance healing,particularly in contaminated *** tissue matrices(r-TMs),which include a biologic scaffold of native extracellular matrix and a syn-thetic component for added strength/durability,are designed to take advantage of aspects of both synthetic and biologic *** date,rTMs have not been reported to reinforce the abdominal wall following stoma *** Twenty-eight patients were selected with a parastomal and/or incisional hernia who had received a temporary ileostomy or colostomy for fecal diversion after rectal cancer treatment or *** hernia repair and proximal stoma closure,rTM(OviTex®1S permanent or OviTex®Lpr)was placed to reinforce the abdominal wall using a laparoscopic,robotic,or open surgical ***-operative follow-up was performed at 1 month and 1 *** recurrence was determined by physical examination and,when necessary,via computed tomo-graphy *** endpoints included length of hospital stay,time to return to work,and hospital *** complications of the wound/repair site included presence of surgical site infection,seroma,hematoma,wound dehiscence,or fistula *** The observational study cohort included 16 male and 12 female patients with average age of 58.5 years±16.3 years and average body mass index of 26.2 kg/m^(2)±4.1 kg/m^(2).patients presented with a parastomal hernia(75.0%),in-cisional hernia(14.3%),or combined parastomal/incisional hernia(10.7%).Using a laparoscopic(53.6%),robotic(35.7%),or open(10.7%)technique,rTMs(OviTex®Lpr:82.1%,OviTex®1S:17.9%)were placed using sublay(82.1%)or intraperitoneal onlay(IpOM;17.9%)mesh *** 1-mo

关键词： reinforced tissue matrix reinforced forestomach matrix Ileostomy Colostomy Ostomy takedown Incisional hernia Abdominal wall

Excellent photoluminescence and electrochemical properties of Sm^(3+) doped Ca_(2)MgSi_(2)O_(7) nanophosphor:Display and electrochemical sensor applications

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Journal of rare Earths 2024年第6期42卷 1046-1055,I0002页

作者： r.B.Basavaraj K.Sureshkumar D.p.Aarti M.B.Madhusudana reddy G.Nagaraju T.ramakrishnappa G.r.Navyashree K.r.Venkatesha Babu K.S.Hemalatha Department of physics BMS Institute of Technology and ManagementBangalore560064India Department of Chemistry BMS Institute of Technology and ManagementBangalore560064India Department of Chemistry School of Applied SciencesREVA UniversityBangalore560064India Energy Materials researchLaboratory Department of ChemistrySiddaganga Institute of TechnologyTumakuru57203KarnatakaIndia School of physical Sciences REVA UniversityBangalore560057Indi Department of physics Govt.Science CollegeBengaluru560001India Department of physics Maharani Science College for WomenMaharani Cluster UniversityBengaluru560001India

A series of orange-red light emitting Ca_(2)MgSi_(2)O_(7):Sm^(3+)nanopowders were fabricated via low-cost ecofriendly green combustion technique using Aloe vera gel as *** phase purity of the samples were confirmed by the powder X-ray diffraction(pXrD)*** single-phase tetragonal structure is observed from the pXrD results with no additional impurity *** band gap energy of the fabricated powders was estimated by diffuse reflectance spectra(DrS)and is found to be in the range of 4.01-5.98 eV.A high resolution scanning electron microscope(SEM)was used to study the morphological behaviour of the ***-like structures are observed from the SEM *** particle size was evaluated by transmission electron microscopy(TEM)and is found to be~50 *** interplanar distance is found to be 0.53 *** properties were systematically studied in *** phosphors are successfully excited at 403 nm NUV light,producing reddish-orange characteristic *** emission peaks are centered at 558(^(4)G_(5/2)→^(6)H_(5/2)),607(^(4)G_(5/2)→^(6)H_(7/2))and 645 nm(^(4)G_(5/2)→^(6)H_(9/2)),*** the observed peaks the red emanation(^(4)G_(5/2)→^(6)H_(7/2))is stronger than the orange emission(^(4)G_(5/2)→^(6)H_(5/2))in the current *** photoluminescent concentration quenching is noticed above 5 mol%Sm^(3+)ion doping *** dipole-dipole interaction resulting in cross relaxation is found to be the principal cause of concentration quenching *** color features such as Commission Internationale de I’Eclairage(CIE)and correlated color temperature(CCT)were studied in *** optimized chromaticity coordinates were estimated to be(0.6363,0.3632),which fall in the reddish-orange *** average CCT value obtained is 3362 *** average color purity is found to be~82%.Sm^(3+)incorporated Ca_(2)MgSi_(2)O_(7) samples are possible contender for single white light generation commercial candidates owing to

关键词： Green combustion photoluminescence Orange-red emission Color purity Sensors rare earths

Solid-liquid extraction for yttrium recovery using porous polymeric resin(XAD-7) functionalized with D_(2)EHpA

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Journal of rare Earths 2024年第9期42卷 1764-1773,I0005页

作者： p.A.Martínez-Montoya r.G.Sanchez-Alvarado D.Y.Medina-Velazquez M.L.Carrera-Jota p.Garnica-Chávez A.de J.Morales-ramirez Higher School of Chemical Engineering and Extractive Industries ESIQIEIPNDepartment of Metallurgical EngineeringUPALM S/NCol.LindavistaGustavo A.Madero Cd.de MéxicoC.P07738Mexico Metropolitan Autonomous University Department of MaterialsBasic Sciences and EngineeringAv.San Pablo No.180Col.Reynosa TamaulipasCd.de MéxicoC.P02200Mexico Center for research and Technological Innovation CIITECIPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P02250CDMXMexico

The recovery of yttrium is proposed by applying a solid-liquid extraction process using di-2-ethyl hexylphosphoric acid(D2EHpA) as extracting *** extracting agents were supported on a macro porous polymeric resin XAD-7(solid phase).Yttrium ions extraction and discharge tests were performed,firstly from a synthetic aqueous solution of 100 mg/L Y(liquid phase) at 25℃ with *** effects of pH of aqueous solutions bearing yttrium,volume fraction of extracting agents and the solid/liquid(S/L)ratio on the yttrium recovery were *** most favorable conditions for yttrium ions extraction are;20 vol% D_(2)EHpA functionalized resin,pH=1.5 and an S/L ratio of 10 mg/mL The discharge of yttrium ions was done under the same conditions of extraction stage,using a 2 mol/L [H_(2)SO_(4)] as stripping *** to 80% yttrium is extracted,while 75% yttrium is recovered in the striping *** all experiments,the reaction equilibrium is reached after 20 min,and the kinetics for the extraction stage was determined as a second-order ***,experiments were carried out to discharge the yttriumloaded resins,and it has been determined that the best pH value to strip the Y ions is *** tests of extraction and discharge for yttrium ions show that the functionalized resin can work at least five cycles without decreasing its ***,the proposed process was tested in a real solution with Y ions fro m a waste fluorescent la mp powder leached in H_(2)SO_(4),demonstrating the ability to effectively recover yttrium,separating it from various metals from the studied residue.

关键词： Yttrium recovery rare earth solid-liquid extraction XAD-7 resin Fluorescent lamps recycling Solid-liquid kinetics extraction

Europium recovery process by means of polymeric nanoparticles functionalized with acrylic acid,curcumin and fumaramide

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Journal of rare Earths 2024年第10期42卷 1950-1959页

作者： p.A.Martínez-Montoya J.M del río A.de J.Morales-ramirez M.Corea Escuela Superior de Ingeniería Química e Industrias Extractivas ESIQIE-IPNDepartamento de Ingeniería Metalúrgica UPALM S/N Col.LindavistaGustao A.MaderoCDMXC.P.07738Mexico Escuela Superior de Ingenieria Química e Industrias Extractivas ESIQIE-IPNLaboratorio de Investigación en Polímeros y NanomaterialesUPALM S/N Col.LindavistaGustavoA.MaderoCDMXC.P.07738Mexico Centra de Investigación e Innovación Tecnológica CIITEC-IPNCda.de CECATIs/nSanta CatarinaAzcapotzalcoC.P.02250CDMXMexico

polymeric nanoparticles of poly(methyl methacrylate)were obtained by emulsion polymerization techniques in a proce ss of two *** particles were functionalized with acrylic acid,curcumin,and fumaramide and three series of polymeric particles were *** incorporation of functional groups was confirmed by Fourier transform-infrared spectrosocopy(FT-Ir)and ultraviolet-visible(UV-Vis)*** spherical morphology of particles with an average diameter of 100 nm was observed by scartning electron microscopy(SEM).The polymeric materials were used for recovery of[Eu]from synthetic *** nanoparticles show excellent chelation capacity to trap rare-earth ions,because they recover more than 85%of[Eu]at pH of *** images of SEM after extraction process show arrays between particles with larger average particle sizes to 1.5 *** addition,the particles have a good stripping capacity,exceeding 50%of it,maintaining their homogeneity in morphology and good stability in dispersion for the recovery and stripping processes.A pseudo-second model order is obtained for the extraction and stripping processes while the best results of stripping process are obtained at pH of 6.

关键词： [Eu]recovery Chelating effect Extraction process Stripping process Emulsion polymerization rare earths