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中型海洋围隔生态系中汞通量、形态和收支的研究

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海洋与湖沼 1986年第4期 307-317页

作者：陆贤崑 k.w.johnson f.a.whitney c.s.wong 吴晋平山东海洋学院海洋科学研究所海洋科学研究所海洋科学研究所国家海洋局第三海洋研究所青岛悉尼加拿大悉尼加拿大悉尼加拿大厦门

在海洋围隔生态系实验中加入迄今最低浓度的无机汞,以研究汞的迁移通量、形态分布和收支。加汞后,汞从水柱中被排除的行为可用一级反应动力学描述。在该生态系内汞被排除的半寿期,与初级生产力和浮游植物特性如个体大小、浮游能力等有... 详细信息

在海洋围隔生态系实验中加入迄今最低浓度的无机汞,以研究汞的迁移通量、形态分布和收支。加汞后,汞从水柱中被排除的行为可用一级反应动力学描述。在该生态系内汞被排除的半寿期,与初级生产力和浮游植物特性如个体大小、浮游能力等有关。对照围隔生态系内,0.01μg Hg/cm2·a的汞垂直通量与海湾现场测量值一致。在自然条件下,溶解汞是水中的主要形态,占73％。加汞后,颗粒汞迅速上升,可达70％以上。浮游植物对汞的富集因子为10～5级。汞在沉积物、器壁和水体中的回收只占52.3％。

关键词：围隔生态系总汞初级生产力生物生产力浮游植物水生植物鞭毛藻颗粒汞硅藻无机汞收支

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海水中ng/Ⅰ级汞的贮存及行为研究

分析化学 1986年第2期 98-101+89页

作者：陆贤崑 k.w.johnson c.s.wong 山东海洋学院化学系 Institute of Ocean sciences B.c.sidhey canada Institute of Ocean sciences B.c.sidhey canada

关于天然水含汞样品的贮存问题,已经研究了十年以上。多数作者认为,贮存天然水样的主要问题来自汞在容器壁上的吸附,造成样品汞损失严重。汞的挥发损失被认为是第二个重要误差来源。但对上述两种损失的比例,不同作者的结果相差较远。另... 详细信息

关于天然水含汞样品的贮存问题,已经研究了十年以上。多数作者认为,贮存天然水样的主要问题来自汞在容器壁上的吸附,造成样品汞损失严重。汞的挥发损失被认为是第二个重要误差来源。但对上述两种损失的比例,不同作者的结果相差较远。另外,容器内汞的溶出沾污也被认为是贮存时的可能误差来源。保存天然水样品的方法可归为选择适当保护剂及适当容器。保护剂可分为:酸(硝酸、硫酸等),氧化剂(高锰酸钾、过硫酸钾、四氯代金酸等),以及络合配位体(氯离子、碘离子、氰离子等)。常用容器有Pyrex等硬质玻璃瓶、聚乙烯或聚四氟乙烯容器。不过不同作者对容器材料和保护剂类型所提出的结果有时相互矛盾。作者认为,容器预处理、样品介质、分析方法灵敏度,尤其是样品中汞浓度,都会对结果产生重大影响。目前,外海海水汞的浓度范围在0.5—8ng/L。比七十年代中期测得范围低约一个数量级。该低含量汞的海水贮存性质,尚缺具体研究。本文取加拿大沙奈奇湾(saanich Inlet)天然海水,用不同容器和保护剂,进行贮存实验研究。

关键词：海水保护剂 ng 聚乙烯瓶无机汞聚四氟乙烯含氟高聚物

MEAsUREMENT Of PRIMARY PRODUcTION IN AN ENcLOsED wATER cOLUMN

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Acta Oceanologica sinica 1986年第4期5卷 584-592页

作者：吴晋平 ,f.a.whitney,c.s.wong Institute of Ocean sciences sidney B.c. canada Institute of Ocean sciences sidney B.c. canada

A cEE (2.5 m by 16 m) has been used to study the budget of organic production by measuring the changes in POc/N, oxygen and 14cO, uptake through three-week period. 14c primary production measurements were conducted with 4-hours and 24-hours incubation periods, and with size fractionation. Different types and sizes of bottle effects were examined. Results showed that the oxygen method production was highest, followed by the 14cO2 uptake method, and POc gain showed the lowest. The value of PQ should be more than 1.7. The ratio of 4-hour incubation to 24-hour incubation was 2.42±0.22, indicating that net daily production is equal to 9.7±0.9 h of illuminated growth. Different types and sizes of bottles had little effect on primary production.

关键词： than MEAsUREMENT Of PRIMARY PRODUcTION IN AN ENcLOsED wATER cOLUMN POc

cost effectiveness of nonpharmacological prevention programs for diabetes:A systematic review of trial-based studies

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chronic Diseases and Translational Medicine 2024年第1期10卷 12-21页

作者： Yongyi Xiong Zhaohua Huo samuel Y.s.wong Benjamin H.k.Yip Jockey club school of Public Health and Primary care Prince of Wales HospitalThe Chinese University of Hong KongShatinHong KongChina

Trial-based economic value of prevention programs for diabetes is *** aimed to review the cost-effectiveness of nonpharmacological interventions to prevent type-2 diabetes mellitus(T2DM)for high-risk *** electronic databases were searched up to March *** assessing both the cost and health outcomes of nonpharmacological interventions for people at high-risk of T2DM were *** quality of the study was assessed by the consolidated Health Economic Evaluation Reporting standards 2022 *** primary outcome for synthesis was incremental cost-effectiveness ratios(IcER)for quality-adjusted life years(QALYs),and costs were standardized in 2022 Us *** synthesis was performed,considering different types and delivery methods of *** studies included five based on the Us diabetes prevention program(DPP),six on non-DPP-based lifestyle interventions,four on health education,and one on screening plus lifestyle *** with usual care,lifestyle interventions showed higher potential of cost-effectiveness than educational *** lifestyle interventions,DPP-based programs were less cost-effective(median of IcERs:$27,077/QALY)than non-DPP-based programs(median of IcERs:$1395/QALY)from healthcare perspectives,but with larger decreases in diabetes ***,the cost-effectiveness of interventions was more possibly realized through the combination of different delivery *** interventions to prevent T2DM in high-risk populations are both cost-effective and feasible in various ***,economic evidence from low-and middle-income countries is still lacking,and interventions delivered by trained laypersons and combined with peer support sessions or mobile technologies could be potentially a cost-effective solution in such settings with limited resources.

关键词： economic evaluation nonpharmacological interventions pre-diabetes prevention

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Mass spectrometry-based proteomics technology in pancreatic cancer research

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胰腺病学杂志(英文) 2024年第2期07卷 145-163页

作者： sun Xue wang siyuan wong catherine c.L. first school of clinical Medicine Peking University Health Science Center Peking University Beijing China school of Pharmacy University of Wisconsin-Madison Madison Wisconsin United States state key Laboratory of complex severe and Rare Diseases Clinical Research Institute Peking Union Medical College Hospital Chinese Academy of Medical Science &amp Peking Union Medical college Beijing China Tsinghua-Peking University Joint center for Life sciences Tsinghua University Beijing China

Pancreatic ductal adenocarcinoma (PDAc) has become a significant health concern with increasing incidence and mortality rates over the past few decades. Researchers have turned their attention to cutting-edge mass spectrometry (Ms) technology due to its high-throughput and accurate detection capacity, which plays a vital role in understanding the mechanisms and discovering biomarkers for pancreatic diseases. In this review, we comprehensively investigate various methodologies of quantitative and qualitative proteomics Ms technologies, alongside bioinformatical platforms employed in pancreatic cancer research. The integration of these optimized approaches provides novel insights into the molecular mechanisms underlying tumorigenesis and disease progression, ultimately facilitating the discovery of potential diagnostic, prognostic biomarkers, and therapeutic targets. The robust Ms-based strategy shows promise in paving the way for early diagnosis and personalized medicine for pancreatic cancer patients.

关键词： Biomarkers Mass spectrometry Pancreatic cancer Pancreatic ductal adenocarcinoma Proteomics

Tribological behavior of lubricant-impregnated porous polyimide

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friction 2024年第4期12卷 711-725页

作者： Jinbang LI Ningning ZHOU Janet s.s.wong school of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China Beijing key Laboratory of Long-life Technology of Precise Rotation and Transmission Mechanisms Beijing Institute of Control EngineeringBeijing 100029China Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK

Porous materials impregnated with lubricants can be used in conditions where limited lubricant is *** this work,three porous polyimides(PPI)with different densities were ***(PAO)impregnated PPI(iPPI)discs were rubbed against steel and sapphire *** operando observations of the iPPI-sapphire contacts show that oil is released under an applied load,forming a meniscus around *** at the outlet is created at high sliding *** amount of released oil increases with increasing PPI *** moduli,E*,estimated based on the actual contact size show that trapped oil in iPPIs contributes to load *** higher speeds,tribological rehydration of the contact occurs in low density iPPI,with that E*rises with *** high density PPIs,high speeds give a constantly high E*which is limited by the viscoelastic properties of the PPI network and possibly the rate of oil *** of iPPI-steel contacts is governed by the mechanical properties of the PPI,the flow of the lubricant,and the roughness of the PPI *** low-and medium-density(highly porous,high roughness)PPIs,large amount of oil is released,and lubrication is mainly via lubricant restricted in the contact in the pores and possibly tribological *** high density(low porosity)PPI,with lower roughness,hydrodynamic lubrication is achieved which gives the lowest *** results show that polymeric porous materials for effective lubrication require the optimization of its surface roughness,stiffness,oil flow,and oil retentions.

关键词： polyimide porous material friction mechanism polymer limited lubrication

Artificial intelligence analysis of videos to augment clinical assessment:an overview

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Neural Regeneration Research 2024年第4期19卷 717-718页

作者： David c.wong stefan williams University of Leeds Leeds Teaching Hospitals Trust LeedsUK

Observation is a fundamental part of the practice of clinical *** of movement is particularly important for the *** such as Parkinson’s disease,multiple sclerosis,stroke,epilepsy,and many others affect a person’s movement in characteristic *** some conditions,changes in the patient’s voice can be included in this-changes in sound caused by changes in the movements of *** clinician’s detection of a characteristic abnormality,and their judgment of its severity,plays a central role in both diagnosis and the assessment of prognosis or response to ***,that practice depends upon a limited resource of experienced *** addition,these experts are limited by human visual judgment,which cannot reliably or precisely detect and measure small or subtle changes in movement(williams et al.,2023).

关键词： clinical epilepsy diagnosis

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DIsTRIBUTION Of DIssOLVED AND PARTIcULATE TRAcE METALs IN ANOXIc sEAwATER, sAANIcH INLET, B . c. cANADA

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chinese Journal of Oceanology and Limnology 1992年第1期10卷 75-83页

作者：詹滨秋 c.s.wong k.w.johnson Institute of Oceanology Academia Sinica Qingdao 266071 Institute of Ocean sciences Canada

This paper discusses the spatial and seasonal distribution character of dissolved and paniculate trace metals in the anoxic seawater of saanich Inlet, B.c., canada. The study showed that concentration of dissolved and paniculate trace metals in anoxic seawater is closely related to (1) the concentration of H2s and the depth of the O2-H2s interface, (2) the exchange of seawater in saanich Inlet with outside seawater, (3) biotic action, and (4) the flushing event. The study was based in part on the ratio between trace metals and nutrients. There was a steep change in the concentration of dissolved trace metals at the O2-H2s interface. The concentration of dissolved trace metals in the H2s-controlled zone was dependent on the H2s there. The suspended matter in saanich Inlet comes from the Hero strait seawater, phytoplankton production and resuspension of flushed-up sediments. The concentration of particulate trace metals was rather low in saanich Inlet and tended to increase with depth. The total

关键词： distribution trace metal seawater

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THE EffEcT Of MINE TAILINGs ON LEVELs Of HEAVY METALs IN sEAwATER

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Acta Oceanologica sinica 1986年第03期5卷 401-415页

作者： c.s.wong,f.a.whitney,w.k.johnson,LU XIANkUN,wUJINPING,wUsHENGsAN,LIJINXIA Ocean chemistry Division Institute of Ocean sciences sidney B.c. canada Ocean chemistry Division Institute of Ocean sciences sidney B.c. canada Ocean chemistry Division Institute of Ocean sciences sidney B.c. canada shandong college of Oceanology Qingdao china Third Institute of Oceanography state Oceanic Administration Xiamen china Third Institute of Oceanography state Oceanic Administration Xiamen china Third Institute of Oceanography state Oceanic Administration Xiamen china

changes in levels of heavy metals in seawater resulting from the addition of mine tailings were studied using plastic enclosures. Nominal concentrations of 10 mg l-1 and 100 mg l-1 of mine tailings from a B. c. molybdenum mine were added, and the metal levels were followed together with sedimentation rates, particle size distribution and other oceanographic and biological time-series parameters over sixteen days. No substantial elevation in levels of zinc, cadmium and copper was observed in the tailing bags compared to that in a background control bag with no addition of tailings. Lead showed a substantial increase in seawater following tailing addition and its removal apparently was with detritus settling following a plankton bloom, and inorganic settling of fine tailing particles.

关键词： Pb THE EffEcT Of MINE TAILINGs ON LEVELs Of HEAVY METALs IN sEAwATER cd