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SOME RESEARCHES ON GAUGE THEORIES OF GRAVITATION

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Science in China,Ser.A 1979年第6期 628-636页

作者：邹振隆黄硼张元仲李根道安瑛陈时吴詠时何祚庥张历宁郭汉英 Institute of Physics Academia Sinica Academia Siniea Institute of Mathomatics Institute of Theoretical Physics Academia Sinic

It is suggested that the geometrical properties of space-time with some gauge symmetries can be determined by the physical properties of matter with the same gauge symmetries. With this principle taken as the guide, it is proposed that several different gauge theories of gravitation such as the Lorentz, the Poincaré, and the de Sitter groups, may be regarded as certain gauge groups in our schemes respectively. Moreover, all of them are not in contradiction with the existing experiments and observations. This perhaps throws a light on the solution of such difficulties as singularity and non-renormalizability in general relativity.

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VALUE OF THE PUMONARY VALVE ECHOGRAM IN ESTIMATING PULMONARY ARTERY PRESSURE

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Chinese Medical Journal 1981年第11期

作者：刘汉英李建蓉胡旭东蔡如升 Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical SciencesBeijing

Pulmonary valve echoes are valuable inassessing pulmonary arterial pressure and rightventricular *** the presenttechnic some indices have been already obtainedsuch as a wave amplitude and right ventricularsystolic time intervals,which can be utilized toestimate pulmonary arterial pressure to recognizethe presence of severe pulmonary ***,it is still a qualitative or semi-quan-titative technic and this insufficiency needs fur-ther investigation to improve the accuracy ofthis noninvasive technic for estimating pul-monary arterial pressure.

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ANIMAL MODEL OF RABBITS FOR RESEARCHING EPIDEMIC HEMORRHAGIC FEVER

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Chinese Medical Journal 1986年第3期

作者：朱智勇唐汉英付桂明翁景清姚顺荣

This study reveals that the rabbit is susceptible to all epidemic hemorrhagic fever virus strains isolated from both wild rodents and humans with epidemic hemorrhagic fever. Specific fluorescence for epidemic hemorrhagic fever virus antigen was detected in many kinds of rabbit tissue, especially in the spleen,small intestine and pancreas on the 7th-13th day of experimental infection. Using fluorescence antibody positive lungs of wild rodents, epidemic hemorrhagic fever virus can easily be isolated in rabbits as well as Apodemus agrarius. Viremia was detected in rabbits on the 4th-6th day after inoculation of epidemic hemorrhagic fever virus. Epidemic hemorrhagic fever virus strains can be serially passaged in rabbits. Therefore, the rabbit provides a new animal model for the isolation and propagation of epidemic hemorrhagic fever virus and for testing the safety of epidemic hemorrhagic fever vaccine.

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Effect of Ligustrazine on CD_(34) Antigen Expression of Bone MarrowCells in Immune-Induced Aplastic Anemia Mice

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Chinese Journal of Integrative Medicine 1998年第2期4卷 148-148页

作者：舒砚君孙汉英董凌莉徐慧珍路武刘文励

Objective:To explore the effect of ligustrazine on CD34 antigen expression of bone marrow cells in immune-induced aplastic anemia（AA）***:The model of immune aplastic anemia mice was in duced by means of 6.0GY60γ-rayirr adi at ion and lym phocyte infusion through tail *** dAA micewere divided into 3 groups:thenormal group,the AA control group and the ligustrazine *** the ligustrazine group were fed by 4 mg of ligustrazine in jecti on twicea day bygastro *** the 10 thday,CD34 an tigen expression intensity of bone marrow cell membrane was measured by flowcy tometer an alysis ***:CD34 antigen expressionin tensity of ligustrazine group was 77.6±6.5,with no statistic difference from that in normal group（80.0±2.6),while that of the control group was muchhigher（68.6±4.5,P＜0.05).Conclusion:Ligustrazine could promote proliferation of stem and progenitor cell of AA mice through in fluencing on bone marrowmicro-environment so as to increase the CD34antigen expression of bone marrow cells.

关键词： Effect of Ligustrazine on CD Cells in Immune-Induced Aplastic Anemia Mice Antigen Expression of Bone Marrow

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Effect of Ligustrazine on Expressions of Basic Fibroblast Growth Factor and Its Receptor in Bone Marrow of Mice with Acute Radiation Injury

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Chinese Journal of Integrated Traditional and Western Medicine 2004年第3期10卷 225-225页

作者：吴宁孙汉英刘文励孟凡凯刘振芳徐慧珍路武谢瑶 Department of Hematology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan (430030)

Objective: To study the expressions of basic fibroblast growth factor (bFGF) and its receptor (bFGFR) in bone marrow of mice with acute radiation injury, and to evaluate the effect of Ligustrazine (Lt) on them. Methods: Fifty-six Kunming mice of clean grade were randomly divided into 3 groups, the normal group, the control group and the Lt group. Mice in the latter two groups were once homogeneously systemic irradiated with 6.0 Gy of 60 Co, with the absorption dose rate of 0. 56 Gy/min, then treated with saline (0.2 ml/ mice) or Lt (2 mg/mice) respectively, twice a day through gastrogavage for successive 13 days. Mice were sacrificed in batch on the 3rd, 7th and 14th day by cervical dislocation to collect the bilateral femoral bone marrow for preparing bone marrow mono-nuclear cell (BMMNC) suspension. The bFGFR expression on surface of BMMNC was determined by flow cytometry; and the bFGF expres-sion level in one side of femoral bone marrow tissue was detected by immunohistochemistry with SABC-AP assay. Results: The bFGF expression in bone marrow of mice on the 3rd, 7th and 14th day after acute radiation injury all were significantly lower than that of the normal mice (P<0.05 or P<0.01). The expressions of bFGF and bFGFR in the Lt group detected were significantly higher than that in the control group detected at the corresponding time points (P<0.05 or P < 0.01). Conclusion:By way of enhancing bFGF expression in bone marrow and bFGFR expression on surface of BMMNC to accelerate the repairing of hemopoietic micro-environment in bone marrow might be one of the mechanisms of Lt in promoting hemopoietic function reconstitution after acute radiation *** article on CJITWM (Chin) 2004;24(5):439

关键词： Effect of Ligustrazine on Expressions of Basic Fibroblast Growth Factor and Its Receptor in Bone Marrow of Mice with Acute Radiation Injury

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PRELIMINARY CLINICAL EXPERIENCE WITH CHINESE BIOPROSTHETIC HEART VALVES

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Chinese Medical Journal 1981年第7期

作者：郭加强朱晓东支启华唐岳锋周其文乐效翚陈宝田宫殿富唐承君刘汉英 Department of Cardiovascular Surgery Fuwai Hospital and Cardiovascular InstituteChinese Academy of Medical SciencesBeijing

From May 1976 to January 1980,100 cases ofcardiac valve replacement performed at FuwaiHospital are *** made hetcroge-nous bioprosthetic bovine pericardial(ModelBN)and porcine aortic valve with elastic stent(Model BZ)were used.21 aortic valve replace-ment(AVR),72 mitral valve replacement(MVR)and 7 double valve replacements were *** of 106(81 BN and 25 BZ)bioprostheticvalves were *** characteristics of the BNand BZ prostheses are *** the patients operated upon,34% hadClass Ⅳ cardiac function(the New York HeartAssociation criteria).The operative mortality(13 cases)was 13%.There were 8 cases withClass Ⅳ function among the fatalities.87 casesare living,45 of 50 had Classes Ⅰ-Ⅱ improvementin cardiac function during 6-42 months’follow-up(mean 14.8 months).Postoperative radio-grams showed marked reductions in cardiac *** early results of these 2 types of Chinesemade bioprostheses are rather *** the bioprostheses in vivo and improvementof cardiac function evaluated by echocardio-graphy are briefly *** prosthetic dysfunction has been observ-ed,but long term durability of these valvesremains to be established.

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