检索结果-南通市图书馆

中国农资 2018年第S1期 23-23页

作者：王旭波孙希园高悦涛张宏宇张祝陶郭振全中国农资传媒三农调研咨询中心中农集团控股股份有限公司磷复肥部山东优配土壤配肥连锁有限公司中国农资扶余测土配肥站吉林省扶余市增盛镇兴华村吉林省前郭县八郎乡八郎农场

主持人:目前在吉林市场上,农民对中农控股的产品及中国农资智能农服体系持什么样的态度?张祝陶:目前我们农民种地主要还是靠自己的经验,化肥损失是比较多的,所以我感觉中国农资智能农服体系是未来的发展方向。不过需要说明的是,尽管农... 详细信息

主持人:目前在吉林市场上,农民对中农控股的产品及中国农资智能农服体系持什么样的态度?张祝陶:目前我们农民种地主要还是靠自己的经验,化肥损失是比较多的,所以我感觉中国农资智能农服体系是未来的发展方向。不过需要说明的是,尽管农民对测土配肥、飞防很感兴趣,但是很多人还是要考虑价格因素,如果价格过高,农民不会买账。

关键词：测土配肥配肥站农资产品中国农资农产品

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

725例手足口病患儿的护理体会

引用

安徽医学 2008年第4期29卷 370-370页

作者：祖大玲张祝娟董玉萍丁红美张莉亚梁桂芳阜阳市第二人民医院护理部 236015

目的总结手足口病的护理要点。方法对725例手足口病患儿采取相关护理措施。结果对725例患儿,特别是重症患儿,通过采取相关护理措施达到预期效果。结论对突发性传染病,尽快掌握其护理要点,可以大大地提高治愈率,降低死亡率并控制疫情的... 详细信息

目的总结手足口病的护理要点。方法对725例手足口病患儿采取相关护理措施。结果对725例患儿,特别是重症患儿,通过采取相关护理措施达到预期效果。结论对突发性传染病,尽快掌握其护理要点,可以大大地提高治愈率,降低死亡率并控制疫情的扩散。

关键词：手足口病护理儿童突发性传染病

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction

Repression of P66Shc expression by SIRT1 contributes to the ...

引用

第八届海峡两岸心血管科学研讨会

作者：周爽陈厚早万言珍张庆军韦玉生黄帅刘金晶鲁云彪张祝琴杨瑞峰张然才华刘德培梁植权 The National Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences & Peking Union Medical College Division of Molecular Medicine Departments of Anesthesiology and MedicineCardiovascular Research LaboratoriesUniversity of California Los Angeles(UCLA)Los AngelesCAUSA

＜正＞Rationale Inactivation of the p66Shc adaptor protein confers resistance to oxidative stress and protects mice from aging - associated vascular ***,there is limited information about the negatively regulating mechanisms of p66Shc expression in the vascular *** In this study,we investigated the role of SIRT1,a classⅢhistone deacetylase,in the regulation of p66Shc expression and hyperglycemia -induced endothelial *** and Results Expressions of p66Shc gene transcript and protein were significantly increased by different kinds of ClassⅢhistone deacetylase（sirtuin） inhibitors in human umbilical vein endothelial cells（HUVECs） and 293A *** overexpression of SIRT1 inhibited high glucose - induced p66Shc upregulation in *** of SIRT1 increased p66Shc expression in high glucose conditions,and also increased the expression levels of plasminogen activator inhibitor 1 （PAI-1） expression,but decreased manganese superoxide dismutase（MnSOD） ***, knockdown of p66Shc significantly reversed the effects of SIRT1 knockdown under high glucose conditions in ***,compared to streptozotocin - induced wild - type diabetic mice,endothelium - specific SIRT1 transgenic（SIRT1 -Tg） diabetic mice had decreased p66Shc expression at both the mRNA and the protein levels,improved endothelial function and reduced accumulation of nitrotyrosine and 8 - OHdG（markers of oxidative stress）.We further found that SIRT1 was able to bind to the p66Shc promoter,resulting in a decrease in the acetylation of histone H3 bound to the p66Shc promoter *** Our findings indicate that repression of p66Shc expression by SIRT1 contributes to the protection of hyperglycemia - induced endothelial dysfunction.

关键词： endothelial dysfunction diabetes gene regulation SIRT1 p66Shc

来源： cnki会议评论