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中国误诊学杂志 2011年第3期11卷 747-747页

作者：崔凤梅肖红杰赵燕辛丽君马海英闫玉娟李俊颖邓志鸿谢延香河北省承德医学院附属医院河北承德067000

目的了解医务人员乙肝疫苗复种意识与认知现状。方法对承德市5所医院不同科室615名医务人员进行问卷调查。结果有效答卷610份,感染性疾病科人员回答正确率及愿意复种乙肝疫苗人数明显高于其他科室人员。结论我们需要对医务人员进行乙肝... 详细信息

目的了解医务人员乙肝疫苗复种意识与认知现状。方法对承德市5所医院不同科室615名医务人员进行问卷调查。结果有效答卷610份,感染性疾病科人员回答正确率及愿意复种乙肝疫苗人数明显高于其他科室人员。结论我们需要对医务人员进行乙肝疫苗复种加强免疫注射预防乙型肝炎相关知识的培训,促使他们加入到宣传乙肝疫苗复种预防乙型肝炎的队伍中来,推动承德市乙型肝炎免疫预防工作的开展。

关键词：医务人员,医院肝炎疫苗,乙型接种

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CELL-MEDIATED IMMUNE RESPONSE IN VIRAL HEPATITIS B

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Chinese Medical Journal 1980年第2期

作者：张定凤刘帮媛刘祖崇崔凤笙 Department of Infectious Diseases Second Hospital of Chongqing Medical College Chongqing

The authors have carried out a series of study, including the cell-mediated immunity to HBsAg and liver specific protein (LSP), lymphocyte subpopulation and rosette inhibitory factor among 113 cases of viral hepatitis B of various types. The cell-mediated immunity to HBsAg and LSP was more intense in acute and chronic active hepatitis, but less so in chronic persistent hepatitis and asymptomatic carriers. The cell-mediated immunity varied with antiHBs, and the higher the cell-mediated immunity to HBsAg, the lower the titer of serum HBsAg. The nonspecific T cell functions including E rosette lymphocyte count, positive rosette inhibitory factor (RIF) and delayed cutaneous reactivity varied inversely with the specific cell-mediated immunity and anti-HBs. The authors believe that type B hepatitis is a disease of immune network imbalance in which T cell defect must play the leading role. The defect of T cell function in chronic active hepatitis and fulminant hepatitis is predominantly due to RIF.

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