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Delamination Testing of AlSi10Mg Sandwich Structures with pyramidal Lattice Truss Core made by Laser powder bed Fusion

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Chinese journal of Mechanical Engineering 2021年第6期34卷 51-62页

作者： M.Nuño j.bühring M.N.Rao K.-U.Schröder Institute of Structural Mechanics and Lightweight Design RWTH Aachen UniversityWüllnerstraβe 752072 AachenGermany

Sandwich structures possess a high bending stiffness compared to monolithic structures with a similar *** makes them very suitable for lightweight applications,where high stiffness to weight ratios are *** common manufacturing methods of sandwich structures involve adhesive bonding of the core material with the ***,adhesive bonding is prone to delamination,a failure mode that is often difficult to *** paper presents the results of delamination testing of fully additive manufactured(AM)AlSi10Mg sandwich structures with pyramidal lattice truss core using Laser powder bed Fusion(LpbF).The faces and struts are 0.5 mm thick,while the core is 2 mm *** inclination of the struts is 45°.To characterise the bonding strength,climbing drum peel tests and out-of-plane tensile tests are *** formulas are derived to predict the expected failure loads and *** analytics and tests are supported by finite element(FE)*** the analytic approach,design guidelines to avoid delamination in AM sandwich structures are *** study presents a critical face sheet thickness to strut diameter ratio for which the structure can *** ratio is mainly influenced by the inclination of the *** peel tests resulted in face yielding,which can also be inferred from the analytics and *** out-of-plane tensile tests didn’t damage the structure.

关键词： Additive Manufacturing Sandwich Structures pyramidal Lattice Core

Identification of CD13,CD107a,and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-de-pendent upregulation

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Cell Research 2005年第5期15卷 325-335页

作者： Florian hENNERSDORF,Stefan FLORIAN,Andreas jAKOb,Katharina bAUMGRTNER,Karoline SONNECK,Alfred NORDhEIM,Tilo bIEDERMANN,peter VALENT,hans-jrg bühring University Clinic of Tübingen Department of Internal Medicine II Division of hematology and Immunology Tübingen Germany Medical University Clinic of Vienna Department of Internal Medicine I Division of hematology and hemostaseology Vienna Austria University of Tübingen proteome Center Tübingen Germany University Clinic of Tübingen Department of Internal Medicine II Division of hematology and Immunology Tübingen Germany Medical University Clinic of Vienna Department of Internal Medicine I Division of hematology and hemostaseology Vienna Austria University of Tübingen proteome Center Tübingen Germany University Clinic of Tübingen Department of Dermatology Tübingen Germany Medical University Clinic of Vienna Department of Internal Medicine I Division of hematology and hemostaseology Vienna Austria University Clinic of Tübingen Department of Internal Medicine II Division of hematology and Immunology Tübingen Germany

Using two-colour flow cytometry >200 antibodies submitted to the 8th International Workshop of human Leukocyte Differentiation Antigens (hLDA8) have been analyzed for their reactivity with resting and activated CD203c+ basophils. Four antibodies either non-reactive or weakly reactive with resting basophils exhibited an increased reactivity with basophils activated by anti-IgE-mediated cross-linking of the high affinity IgE receptor (FcεRI). These include antibod- ies against CD164 (WS-80160, clone N6b6 and WS-80162, clone 67D2), as well as two reagents with previously unknown specificities that were identified as CD13 (WS-80274, clone A8) and CD107a (WS-80280, clone E63-880). The activation patterns followed either the “CD203c-like” or “CD63-like” activation profile. The CD203c profile is characterized by a rapid and significant upregulation (of CD13, CD164, and CD203c), reaching maximum levels after 5- 15 min of stimulation. The phosphoinositide-3-kinase (pI3K)-specific inhibitor wortmannin inhibited the upregulation of these markers whereas 12-O-tetradecanoyl-phorbol-13-acetate (TpA) induced a rapid and FcεRI-independent upregulation within 1-2 min. In the CD63 profile, maximum upregulation (of CD63 and CD107a) was detected only after 20-40 min, and upregulation by TpA reached maximum levels after 60 min. In summary, our data identify CD13, CD107a, and CD164 as novel basophil-activation antigens. based on time kinetics of upregulation, we hypothesize that molecules of the “CD203c group” and the “CD63 group” are linked to two different mechanisms of basophil activation.

关键词： CD203c CD164 CD63 CD107a basophil activation basophil marker.

Arsenic and sulfur nanoparticle synthesis mimicking environmental conditions of submarine shallow-water hydrothermal vents

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journal of Environmental Sciences 2022年第1期34卷 301-312页

作者： Vicente Durán-Toro Kurosch Rezwan Solveig I.bühring Michael Maas MARUM–Center for Marine Environmental Sciences University of BremenBremen 28359Germany Advanced Ceramics University of BremenBremen 28359Germany MApEX-Center for Materials and processes University of BremenBremen 28359Germany

Arsenic and sulfur mineralization is a natural phenomenon occurring in hydrothermal systems where parameters like temperature and organic matter(OM)can influence the mobilization of the toxic metalloid in marine *** the present study we analyze the influence of temperature and OM(particularly sulfur-containing additives)on As and S precipitation based on the recent discovery of As-rich nanoparticles in the hydrothermal system near the coast of the Greek island *** this end,we experimentally recreate the formation of amorphous colloidal particles rich in As and S via acidification(ph 3–4)of aqueous precursors at various *** higher temperatures,we observe the formation of monodisperse particles within the first 24 h of the experiment,generating colloidal particles with diameters close to 160 *** S:As ratio and particle size of the synthetized particles closely correlates with values for As_(x)S_(y)particles detected in the hydrothermal system off ***,organic sulfur containing additives(cysteine and glutathione,GSh)are a key factor in the process of nucleation and growth of amorphous colloidal As_(x)S_(y)particles and,together with the temperature gradient present in shallow hydrothermal vents,dictate the stabilization of As-bearing nanomaterials in the *** on these findings,we present a simple model that summarizes our new insights into the formation and mobility of colloidal As in aquatic *** this context,amorphous As_(x)S_(y)particles can present harmful effects to micro-and macro-biota not foreseen in bulk As material.

关键词： biomineralization Milos hydrothermal vent Arsenic Sulfur Nanoparticles Ecotoxicology

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南海北部末次间冰期早期的突然降温事件

中国科学（D辑） 2001年第10期31卷 823-827页

作者：涂霞郑范王吉良汪品先蔡慧梅 C.bühring M.Sarnthein 中国科学院南海海洋研究所广州510301 同济大学海洋地质教育部重点实验室上海200092 德国基尔大学地球科学系

南海北部陆坡ODp1144站96.49-137.6 mcd 1)井段的高分辨率浮游有孔虫定量分析与δ18O测定表明末次间冰期(MIS 5.5即5 e)内发生过一次表层海水突然降温的事件, 冬季水温下降幅度可达7.5℃, 表层水δ18O值也下降1.2‰. 此次降温事件在西... 详细信息

南海北部陆坡ODp1144站96.49-137.6 mcd 1)井段的高分辨率浮游有孔虫定量分析与δ18O测定表明末次间冰期(MIS 5.5即5 e)内发生过一次表层海水突然降温的事件, 冬季水温下降幅度可达7.5℃, 表层水δ18O值也下降1.2‰. 此次降温事件在西欧和北大西洋均已发现, 相互可以对比, 但南海记录的降温事件更加强烈. 此次事件推测由中低纬地区而非极地冰盖引起; 由于黑潮标志种pulleniatina obliquiloculata对此次降温事件反映最为强烈, 有可能与西太平洋低纬度地区的古海洋学变化有关. 此次事件可认为属“新仙女木期”式的降温, 表明末次间冰期气候的变异性.

关键词：南海北部末次间冰期突然降温事件 MIS5.5期气候不稳定性古气候学

南海北部ODp1144站颜色反射率揭示的千年尺度气候波动

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海洋地质与第四纪地质 2003年第3期23卷 5-10页

作者：黄维翦知湣 Cbühring 同济大学海洋地质教育部重点实验室上海200092 德国基尔大学地球科学系

南海大洋钻探ODp1144站钻孔长517m,代表近100万年来的沉积记录,其颜色反射率是所有岩心物理性质测试中分辨率最高的,平均约60年一个测值,最高可达年级尺度,是研究千年尺度气候变化的理想材料。通过对颜色反射率、浮游有孔虫氧同位素的... 详细信息

南海大洋钻探ODp1144站钻孔长517m,代表近100万年来的沉积记录,其颜色反射率是所有岩心物理性质测试中分辨率最高的,平均约60年一个测值,最高可达年级尺度,是研究千年尺度气候变化的理想材料。通过对颜色反射率、浮游有孔虫氧同位素的小波分析及其与地球轨道参数ETp的交叉频谱分析,表明两者在轨道周期上的变化极为相似,都反映出约70万年以来100ka的偏心率周期明显占优;与格棱兰冰心的对比亦揭示了颜色反射率同样记录了冰期中的类似D/O事件。对此站的颜色反射率短周期的小波分析,揭示出了约3ka、约1 5ka的变化周期,这些周期不仅仅出现在冰期(如MIS2—4、6、8期等),也出现在间冰期(如MIS15、17、19、25期等)和冰消期(如MIS11/12、15/16),且在70万年以来冰期信号强、间冰期信号弱,而在70万年之前正好相反,这不仅说明间冰期内部气候也存在不稳定性,而且进一步说明了中更新世的气候转型事件。

关键词：千年尺度气候波动大洋钻探颜色反射率古环境短期气候事件

中国南海的多巴火山灰层:74ka左右喷发期间的对比风向证据

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海洋地质动态 2000年第8期16卷 19-20页

作者： Christian bühring 周立君孙萍

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发生于乳房复发性粘液样肉瘤后的双侧乳房癌

德国医学 1996年第2期13卷 119-122页

作者： b.R.Titius U-j.Ghring A.Scharl 武忠弼 Institut für pathologie Universitt zu KlnJoseph-Stelzmann-Str.9D-5093KlnGermany 同济医科大学

肉瘤在乳房恶性肿瘤中的发生率仅占0.5%～3%,脂肪肉瘤则仅占乳腺肉瘤的0.3%,因而与四肢及腹膜后的肉瘤相比仅属罕见。一些脂肪肉瘤是在乳腺纤维腺瘤的基础上恶变而成,或由叶状囊性肉瘤转化而来,其余则为乳腺的原发性肉瘤。本瘤首先由 Vi... 详细信息

肉瘤在乳房恶性肿瘤中的发生率仅占0.5%～3%,脂肪肉瘤则仅占乳腺肉瘤的0.3%,因而与四肢及腹膜后的肉瘤相比仅属罕见。一些脂肪肉瘤是在乳腺纤维腺瘤的基础上恶变而成,或由叶状囊性肉瘤转化而来,其余则为乳腺的原发性肉瘤。本瘤首先由 Virchow 于1857年描述,第一例由 Neumann于1862年报道,迄今共报道近百例。本文1例为26岁患者,原患粘液样内瘤,组织学上未分化并继之以双侧乳房癌。

关键词：乳腺癌粘液样肉瘤病理

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硬质合金刀具的物理镀层方法

国外金属热处理 1990年第3期11卷 37-40页

作者： j.Gühring 李敏政

长期以来硬质合金刀具,特别是硬质合金可转位刀片都采用氮化钛镀层。实践证明,这种镀层是可靠的。近年来发展了一种新的镀层方法。尽管今后仍采用氮化钛镀层,但在多数情况下不再使用化学镀层,而采用物理镀层。下面介绍这种镀层的主要特... 详细信息

长期以来硬质合金刀具,特别是硬质合金可转位刀片都采用氮化钛镀层。实践证明,这种镀层是可靠的。近年来发展了一种新的镀层方法。尽管今后仍采用氮化钛镀层,但在多数情况下不再使用化学镀层,而采用物理镀层。下面介绍这种镀层的主要特点。化学和物理镀层方法 CVD方法是通过几种气体(例如,氯化钛、氢和氮、图1)的化学反应而获得镀层。

关键词：硬质合金刀具物理镀覆

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热处理炉中直接制备气氛及其控制

国外化学热处理 1982年第4期 36-40页

作者： W.Ghring C.h.Luiten 朱保华

用燃料气和空气的混合气或只用燃料气直接送入灼热炉膛所产生的气氛,提供了通常由独立的吸热型发生器所制备气氛的一种切合实用的代用品。作者概述了此二种技术的操作、控制和优点,并着重于渗碳应用。前言吸热型炉气氛通常在吸热型发生... 详细信息

用燃料气和空气的混合气或只用燃料气直接送入灼热炉膛所产生的气氛,提供了通常由独立的吸热型发生器所制备气氛的一种切合实用的代用品。作者概述了此二种技术的操作、控制和优点,并着重于渗碳应用。前言吸热型炉气氛通常在吸热型发生器中,通过催化裂解控制的烧料气和空气的混合气而产生。碳势控制是根据化学平衡的假设。

关键词：碳势控制炉膛混合气热处理炉工业炉窑直接制备燃料气气体燃料渗层深度