检索结果-南通市图书馆

Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection

World Journal of Gastroenterology 2023年第30期29卷 4604-4615页

作者： Gabriella Feilstrecker Balani Mariana dos Santos Cortez Jayme Euclydes Picasky da Silveira Freitas Fabrício freire de Melo Ana Carla Zarpelon-Schutz Kádima Nayara Teixeira Campus Toledo Universidade Federal do ParanáToledo 85.919-899ParanáBrazil Campus Anísio Teixeira Universidade Federal da BahiaInstituto Multidisciplinar em SaúdeVitória da Conquista 45.029-094BahiaBrazil Programa de Pós-graduação em Biotecnologia-Setor Palotina Universidade Federal do ParanáPalotina 85.950-000ParanáBrazil Programa Multicêntrico de Pós-graduação em Bioquímica e Biologia Molecular-Setor Palotina Universidade Federal do ParanáPalotina 85.950-000ParanáBrazil

Many studies point to an association between Helicobacter pylori(***)infection and inflammatory bowel diseases(IBD).Although controversial,this association indicates that the presence of the bacterium somehow affects the course of *** appears that *** infection influences IBD through changes in the diversity of the gut microbiota,and hence in local chemical characteristics,and alteration in the pattern of gut immune *** gut immune response appears to be modulated by *** infection towards a less aggressive inflammatory response and the establishment of a targeted response to tissue ***,a T helper 2(Th2)/macrophage M2 response is stimulated,while the Th1/macrophage M1 response is *** immunomodulation appears to be associated with intrinsic factors of the bacteria,such as virulence factors-such oncogenic protein cytotoxin-associated antigen A,proteins such *** neutrophil-activating protein,but also with microenvironmental changes that favor permanence of *** in the *** changes include the increase of gastric mucosal pH by urease activity,and suppression of the stomach immune response promoted by evasion mechanisms of the ***,there is a causal relationship between *** infection and components of the innate immunity such as the NLR family pyrin domain containing 3 inflammasome that directs IBD toward a better prognosis.

关键词： Cytotoxin-associated antigen A oncoprotein Gut microbiota Helicobacter pylori Helicobacter pylori neutrophilactivating protein Immunological modulation Inflammatory bowel disease NLR family pyrin domain containing 3 inflammasome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long Live Sino-Capeverdean Friendship And Cooperation

引用

Voice of Friendship 2006年第2期 30-31页

作者： Julio Cesar freire de Morais Capeverdean Ambassador to China

Editor’s note: The 30th anniversary of the establishment of diplomatic relations between China and Cape Verde falls on April 25, 2006. Ambassador Julio Cesar freire de Morais wrote the following article for Voice of ... 详细信息

关键词： diplomatic Ambassador occasion Voice dialogue anni

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Generalised Settlement Area:mapping the Earth surface in the vicinity of built-up areas

引用

International Journal of Digital Earth 2020年第1期13卷 45-60页

作者： A.J.Florczyk M.Melchiorri J.Zeidler C.Corbane M.Schiavina S.freire F.Sabo P.Politis T.Esch M.Pesaresi European Commission Joint Research Centre(JRC)Directorate for SpaceSecurity&MigrationIspraItaly Piksel S.r.l MilanoItaly German Aerospace Center(DLR) German Remote Sensing Data Center(DFD)WeßlingGermany Arhs Developments Italia S.r.l.Milano Italy Arhs Developments S.A. LuxembourgLuxembourg

Geo-information on settlements from Earth Observation offers a base for objective and scalable monitoring of the evolution of cities and settlements,including their location,extent and other *** this work,we deploy the best available global knowledge on the presence of human settlements and built-up structures derived from Earth Observation to advance the understanding of the human presence on *** start from a concept of Generalised Settlement Area to identify the Earth surface within which any built-up structure is *** further characterise the resulted map by using an agreement map among the state of the art of remote sensing products mapping built-up areas or other strictly related semantic abstractions as urban areas or artificial *** agreement map is formed by a grid of 1 km2,where each cell is classified according to the number of EO-derived products reporting any positive occurrence of the abstractions related to the presence of built-up *** paper describes the characteristics of the Generalised Settlement Area,the differences in the agreement map across geographic regions of the world,and outlines the implications for potential users of the EO-derived products used in this study.

关键词： Generalised settlement area built-up area human settlement map agreement map

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tailoring the partitioning of proteins using ionic liquids as adjuvants in polymer-polymer aqueous biphasic systems

引用

Green Chemical Engineering 2022年第4期3卷 328-337页

作者： Flavia F.Magalhaes Matheus M.Pereira Rita de Cassia Superbi de Sousa Ana P.M.Tavares Joao A.P.Coutinho Mara G.freire CICECO-Aveiro Institute of Materials Department of ChemistryUniversity of AveiroAveiro3810-193Portugal Separation Process Laboratory(LPS) Department of Food TechnologyFederal University of Viçosa(UFV)P.H.Rolfs Av.s/n36570-000 ViçosaMGBrazil

Aqueous biphasic systems(ABS)are promising for proteins purification;however,when dealing with samples comprising several proteins,the selectivity towards a target protein is difficult to *** this work,the addition of ionic liquids(ILs)as adjuvants(5 wt%and 10 wt%)in ABS composed of polyethylene glycol(PEG)and dextran was investigated to tailor proteins partitioning between the coexisting *** liquid-liquid phase diagrams were determined at 298 K,followed by partition studies of three proteins(bovine serum albumin(BSA),immunoglobulin G(IgG),and cytochrome C(Cyt C)).Partition coefficients of IgG and BSA indicate the preference of both proteins to the dextran-rich phase,whereas Cyt C has no preferential partitioning between the *** addition of chloride-based ILs as adjuvants allows to increase or decrease the partition coefficients,thus tailoring the proteins partitioning between the *** partitioning essentially depends on the IL content in each phase,whereas Cyt C and IgG partitioning is ruled by the ILs chemical structure and established *** docking was carried out to address the ILs effect on the proteins partitioning,supporting experimental observations,while identifying the specific interactions *** partition of each protein in polymer-salt ABS with ILs as adjuvants was determined,demonstrating the higher tailoring ability of polymer-polymer ABS when adding ***,the partition of each protein in presence of the remaining ones was determined,as well as the selectivity of the studied systems to separate each pair of proteins,paving the way for their use in liquidliquid chromatography.

关键词： Aqueous biphasic systems Polymer-polymer systems Protein partition Ionic liquids Adjuvants

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Urban Regeneration Challenge： The Case of Avenidas Novas District in Lisbon

引用

Journal of Civil Engineering and Architecture 2011年第4期5卷 353-362页

作者： Francisco Manuel Camarinhas Serdoura Helena Susete Figueira freire de Almeida Francisco Manuel Camarinhas Serdoura and Helena Susete Figueira freire de Almeida

This paper aims at presenting the guidelines for an urban regeneration strategy in Lisbon, having in account the principles of urbanity, density, livability and social and territorial cohesion. The case study will be Avenidas Novas district, in Lisbon, Portugal, as it is a paradigmatic example of a central area which coexists with dynamism and decadence. The development model for Avenidas Novas was inspired on French boulevards and was planned to be the modem face of a medium to high social class population, as it was until 1940s. Today, as a consequence of further developments which corrupted the first principles and concept, its urban fabric is becoming less coherent and adequate to the needs of the population who works and lives there. From an analysis to the various components of the urban fabric, the paper will identify the major problems that are happening on the site, related to accessibility, mobility and functional diversity. Once understanding the impacts of an unsustainable territory management and urban design, the goal is to develop the principles for a creative urban regeneration strategy for Avenidas Novas district. The study will be based on the theoretical issues of the compact city and walkable distances in order to develop quantifying parameters of urban quality and to promote human scale public spaces and territorial cohesion on an urban environment.

关键词： Urban regeneration compact city spatial analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of nanofertilizer and nano-plant hormone on soil chemical properties and microbial community in two different soil types

引用

Pedosphere 2023年第5期33卷 765-775页

作者： John Lester Viscara PIDE Nolissa Delmo ORGANO Andre freire CRUZ Lilia M.FERNANDO Lucille C.VILLEGAS Evelyn F.DELFIN Michelle Ann Magat CALUBAQUIB Roselle Estera MADAYAG Erlinda S.PATERNO Division of Soil Science Agricultural Systems InstituteCollege of Agriculture and Food Science(CAFS)University of the Philippines Los Baños(UPLB)CollegeLaguna 4031Philippines Graduate School of Life and Environmental Sciences Kyoto Prefectural University1-5 Shimogamohangi-choSakyo-kuKyoto 606-8522Japan Crop Biotechnology Division Institute of Crop ScienceCAFSUPLBCollegeLaguna 4031Philippines Microbiology Division Institute of Biological SciencesCollege of Arts and SciencesUPLBCollegeLaguna 4031Philippines Institute of Plant Breeding CAFSUPLBCollegeLaguna 4031Philippines Isabela State University Cabagan Campus Isabela 3328Philippines

Application of nanotechnology in agriculture has been expanded to improve crop *** impact of nanomaterials(NMs)on factors that influence the survival and function of beneficial microorganisms is a less studied aspect that needs to be better *** a few studies have assessed the effects of NMs on beneficial soil *** study was conducted to assess the effects of nanofertilizer FertiGroe?N(FG-N)and nano-plant hormone HormoGroe?auxin(HG-A)on the chemical properties and microbial communities of two contrasting soils,Lipa clay loam(CL)and Sariaya sandy loam(SL),over a 35-d incubation period in the *** and fungal communities were evaluated using amplicon sequencing analysis within the 16S and internal transcribed spacer regions,*** application of FG-N significantly decreased soil pH,but did not affect total N and available P for both soil types.A significant increase in exchangeable K was observed only in Lipa *** application of HG-A had no significant effect on soil chemical *** the bacterial community after incubation,the relative abundances of Acidobacteriia,Chthonomonadetes,and Saccharimonadia decreased,whereas Acidimicrobiia,Chloroflexia,and Gemmatimonadetes increased with FG-N application in Lipa *** application of HG-A increased the relative abundance of Rubrobacteria,Chthonomonadetes,and Chloroflexia in Lipa *** the fungal community,FG-N application increased the relative abundance of Sordariomycetes,Agaricomycetes,and Eurotiomycetes,whereas Dothideomycetes and Mortierellomycetes decreased in Lipa CL after *** Sariaya SL,FG-N application increased the relative abundance of Dothideomycetes,Eurotiomycetes,and Mortierellomycetes,but decreased that of Sordariomycetes and *** classes observed in the control samples were not detected in the HG-A treatment,but were recovered after incubation in Lipa *** microbial diversity in both soil types showed sl

关键词： amplicon sequencing bacterial community crop production fungal community microbial diversity nanomaterial nanotechnology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gas-Solid Flow Behavior in a Pneumatic Conveying System for Drying Applications: Coarse Particles Feeding with a Venturi Device

引用

Advances in Chemical Engineering and Science 2015年第3期5卷 225-238页

作者： Thiago Faggion de Pádua Rodrigo Béttega José Teixeira freire Department of Chemical Engineering Federal University of S&#227 o Carlos S&#227 o Carlos Brazil

The feeding of coarse particles (>0.5 mm diameter) directly into a riser operating at positive pressure is important for drying and pre-heating applications. The presence of the feeding device can lead to heterogeneity of drying and heating, and is the main factor responsible for pressure loss in short conveying systems. However, there is a lack of information concerning the axial and radial distributions of coarse particles in this type of configuration, despite the recent advances when dealing with fine particles (FCC catalyst). The present work therefore investigates a vertical venturi feeder with the conveying system operating in dilute-phase regime with 1 mm spherical glass particles. Experimental assays revealed the behavior of the mass flow rate of solids in the system, and pressure measurements were made along the riser in order to evaluate the accuracy of simulations. Euler-Euler simulations provided close estimation of the experimental pressure drop and the pressure drop according to distance in the linear region. Simulation of the fluid dynamics in the riser showed that solids clusters were formed at low concentrations near the feeding device, reflecting heterogeneity in the solid phase volume fraction.

关键词： Pneumatic Conveying Venturi Feeder Coarse Particles Drying CFD

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A System Status Definition to Improve Behavior Description in Specifications Based on Constructal Law

引用

Open Journal of Applied Sciences 2018年第8期8卷 315-337页

作者： Luciano Ondir freire Dr. Delvonei Alves de Andrade Daniel Monterrain Instituto de Pesquisas Energéticas e Nucleares (IPEN-CNEN/SP) S&atilde o Paulo Brazil Naval Group Indret La Montagne France

System behavior description using states faces problems like state explosion, lack of clear definition of state, state identification and coordination between multiple agents. The goals of this work are to ease design activity, to reduce engineering efforts, and to mitigate project risks. The proposed way is to improve information flow during design by adding definitions and some protocols or rules for communicating a specification or design description. This work presented an objective definition of system status (way of interaction with the rest of the world) along other concepts. This work focused in definitions as mind entities and their importance to rationalize work and mitigate project risks during design. This article presented some simple examples to illustrate the advantages of each aspect of proposed definition of system status and discussed limits and exceptions for such definition. The key finding was the proposed definition which was the simplest while keeping completeness at a given product breakdown level. Such definition of status enforced formal segregation of needs and solutions, and eased the inclusion of behavior definition in specifications.

关键词： Cyber Systems System Design Constructal Law System Behavior Modelling State Analysis System Engineering

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tricuspid Valve Endocarditis in a Patient with Congenital Heart Disease

引用

Journal of Pharmacy and Pharmacology 2018年第5期6卷 502-508页

作者： Barbara Liss de Sousa freire Suyane Gomes Leite Jose Antonio de Lima Neto Eduardo Ferreira Almeida Joaquim David Carneiro Neto Bruna Theresa de Sousa freire Hospital do Coracao de Sobral Sobral 62042240 Brazil

The present study reports a case of a young patient who presented for 3 months dyspnea, edema of lower limbs, fever and important weight loss. She evolved with acute fever, hematemesis and focal seizures. An echocardiogram was performed demonstrating file presence of interventricular, interatrial, and extensive echogenic imaging and of poorly defined borders throughout the septal cusp of the tricuspid valve, suggestive of vegetation, chest tomography that observed several foci of pulmonary abscess and blood culture evidencing the presence of Staphylococcus aureus. She was treated with Vancomycin, Meropenem and Amphotericin, along with clinical support. She underwent surgery to exchange the tricuspid valve for a biological prosthesis, evolving with clinical improvement and receiving discharge from hospital.

关键词： Congenital heart disease infective endocarditis interventricular communication echocardiography.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Helicobacter pylori infection:How does age influence the inflammatory pattern?

引用

World Journal of Gastroenterology 2022年第4期28卷 402-411页

作者： Glauber Rocha Lima Araújo Hanna Santos Marques Maria Luísa Cordeiro Santos Filipe Antônio França daSilva Breno Bittencourt da Brito Gabriel Lima Correa Santos Fabrício freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094Brazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900Brazil

The inflammatory pattern during Helicobacter pylori(***)infection is changeable and *** childhood,it is possible to observe a predominantly regulatory response,evidenced by high concentrations of key cytokines for the maintenance of Treg responses such as TGF-β1 and IL-10,in addition to high expression of the transcription factor *** the other hand,there is a predominance of cytokines associated with the Th1 and Th17 responses among ***-positive *** the last few years,the participation of the Th17 response in the gastric inflammation against *** infection has been highlighted due to the high levels of TGF-β1 and IL-17 found in this infectious scenario,and growing evidence has supported a close relationship between this immune response profile and unfavorable outcomes related to the ***,this cytokine profile might play a pivotal role in the effectiveness of *** *** is evident that age is one of the main factors influencing the gastric inflammatory pattern during the infection with ***,and understanding the immune response against the bacterium can assist in the development of alternative prophylactic and therapeutic strategies against the infection as well as in the comprehension of the pathogenesis of the outcomes related to that microorganism.

关键词： Helicobacter pylori Inflammation Treg response Th1 response Th17 response Gastric diseases

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：