检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

一座梯田式的曲线书山——天津滨海图书馆

设计家 2017年第3期 98-102页

作者： Winy Maas Jacob van Rijs Nathalie de Vries Wenchian shi María López Calleja Chi Li ángel sánchez navarro Daehee suk Guang Ruey Tan Xichen sun Michael Zhang Kyosuk Lee Mariya Gyaurova Jaime Dominguez Bálgoma Antonio Luca Coco Costanza Cuccato Matteo Artico Tomaso Maschietti Ossip van Duivenbode MVRDV建筑设计事务所

项目地点:天津滨海新区项目面积:33,700平方米完成时间:2017项目功能:图书馆合作建筑师:中国天津市城市规划设计研究院建筑分院室内设计:天津市建筑设计院灯光照明:华谊建源照明设计所有项目资料由MVRDV事务所提供MVRDV与天津城市规划... 详细信息

项目地点:天津滨海新区项目面积:33,700平方米完成时间:2017项目功能:图书馆合作建筑师:中国天津市城市规划设计研究院建筑分院室内设计:天津市建筑设计院灯光照明:华谊建源照明设计所有项目资料由MVRDV事务所提供MVRDV与天津城市规划设计研究院合作建成天津滨海图书馆,于10月正式开放:这个全新的33,700m2文化中心以中庭的发光球形报告厅为焦点,四周环绕着梯田般层叠的书架,书架贯穿中央天井与球体相呼应。波浪式的书架是建筑中的主要空间元素,既界定了空间。

关键词：天津滨海图书馆天津市建筑设计院城市规划设计研究院建筑师建筑体量项目面积

Anti-amyloid antibodies in Alzheimer’s disease: what did clinical trials teach us?

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： Danko Jeremic Lydia Jiménez-Díaz Juan D.navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s disease(AD)may exist,both the original amyloid cascade and tau hypotheses posit that abnormal misfolding and accumulation of amyloid-β(Aβ)and tau protein is the central event causing the ***,that conclusion could be only partly true,and there is conflicting evidence about the role of both proteins in AD,being able to precede and influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand tau proteins may be independently involved in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evidence suggests that Aβand tau act synergistically,rather than additively in disease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer additive

Highly divergent sympatric lineages of Leptotila verreauxi(Aves:Columbidae)suggest a secondary contact area in the Isthmus of Tehuantepec,Mexico

在线全文

学校读者我要写书评

暂无评论

Avian Research 2024年第1期15卷 12-21页

作者： Orlando J.Espinosa-Chávez Adolfo G.navarro-sigüenza Hernando Rodríguez-Correa Luis A.sánchez-González Museo de Zoología“Alfonso L.Herrera” Depto.de Biología EvolutivaFacultad de CienciasUniversidad Nacional Autonoma de MexicoApdo.Postal 70-399CP 04510Ciudad de MexicoMexico Posgrado en Ciencias Biologicas Unidad de PosgradoEdificio D1◦PisoCircuito de PosgradosCiudad UniversitariaUniversidad Nacional Autonoma de MexicoCoyoacanCP 04510CDMXMexico Escuela Nacional de Estudios superiores Unidad Morelia Universidad Nacional Autonoma de Mexico.Antigua Carretera a Patzcuaro No.8701 Col.Ex Hacienda de San Jose de la HuertaC.P.58190MoreliaMichoacanMexico

Due to a complex geological and biotic history,the Isthmus of Tehuantepec(IT),has been long recognized as a driver for the evolutionary divergence of numerous lowland and highland *** distributed in the lowlands of the American continent,the White-Tipped Dove(Leptotila verreauxi)is a polytypic species with 13 recognized *** of these have been recorded in Mexico,and the distribution of three abuts at the IT,suggesting a contact *** estimate phylogenetic patterns,divergence times and genetic differentiation,we examined two mt DNA(ND2 and COI)and one n DNA(β-fibint 7)*** also used correlative ecological niche models(ENM)to assess whether ecological differences across the IT may have acted as a biogeographical *** estimated paleodistributions during the Middle Holocene,Last Glacial Maximum and Last Interglacial,to evaluate the influence of climate changes on the distribution and demographic *** results showed genetically distinct lineages that diverged approximately 2.5 million years *** and ecological factors may have played a dual role in promoting differentiation,but also in the formation of a secondary contact zone in the southern *** ecological niche comparisons indicated that the ecological niche of sympatric lineages at the IT are not identical,suggesting niches divergence;in addition,environmental niche models across the region indicated no abrupt biogeographic barriers,but the presence of regions with low *** results suggest that genetic differentiation originated by a vicariant event probably related to environmental factors,favored the evolution of different ecological ***,the absence of a biogeographic barrier but the presence of less suitable areas in the contact regions,suggest that secondary contact zones may be also maintained by climatic factors for the eastern group,but also by biotic interactions for the western group.

关键词： Biogeographical boundary Humid and dry forests Isthmus of Tehuantepec Phylogeography secondary contact

Analytic Hierarchy Process(AHP)to Optimize the service in a Water supply Network

在线全文

学校读者我要写书评

暂无评论

材料科学与工程（中英文B版） 2020年第1期10卷 10-17页

作者： Jesús Rubén sánchez navarro Carmen Julia navarro Gómez David Humberto sánchez navarro Eduardo Herrera Peraza Faculty of Engineering Autonomous University of ChihuahuaChihuahua 31000México Center for Advanced Materials Research Chihuahua 31136México

Decision making in drinking water supply networks is increasingly complex due to the large number of variables *** order to make better decisions it is necessary to use adequate and robust *** paper presents the application of the Analytic Hierarchy Process(AHP)related to the operation of the drinking water supply network of the city of Chihuahua,Mexico,where two possible alternatives are delineated with the objective to optimize the *** application of AHP was carried out in 24 sectors that have substantial differences in their efficiency but with instrumentation and measurement in all the variables contemplated by the operating agency,with a population of 221,722 inhabitants which represent a 30%of the total population of the city,the results indicate that the best alternative is the one with less criteria to be controlled and fewer repercussions on the cost of operation and investment in the rehabilitation and replacement of the network.

关键词： Optimize multicriteria method decision making AHP water supply network

ApoB-100, ApoE and CYP7A1 gene polymorphisms in Mexican patients with cholesterol gallstone disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第37期16卷 4685-4690页

作者： sánchez-Cuén Jaime Aguilar-Medina Maribel Arámbula-Meraz Eliakym Romero-navarro José Granados Julio sicairos-Medina Laura Ramos-Payán Rosalío División de Gastroenterología Hospital Regional ISSSTE Facultad de Ciencias Químico Biológicas Doctorado en Biotecnología y Maestría en Ciencias Biomédicas Universidad Autónoma de Sinaloa División de Inmunogenética Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

AIM: To determine the possible association of the ApoB100 (Xba Ⅰ ), ApoE (Hha Ⅰ ) and CYP7A1 (Bsa Ⅰ ) gene polymorphisms, with the development of cholesterol gallstone disease (GD) in a Mexican population. METHODs: The polymorphisms were analyzed by polymerase chain reaction followed by restriction fragment length polymorphism, in two groups matched by ethnicity, age and sex: patients with GD (n = 101) and stone-free control subjects (n = 101). REsULTs: Allelic frequencies in patients and controls were: 34.16% vs 41.58% (P = 0.124) for X+of ApoB-100; 4.46% vs 5.94% (P = 0.501) for E2, 85.64% vs 78.22% (P = 0.052) for E3, 9.90% vs 15.84% (P = 0.075) for E4 of ApoE; and 25.74% vs 27.72% (P = 0.653) for C of CYP7A1. Differences in genotypic frequencies between the studied groups were not significant (P sION: These results demonstrated that no association exists between the studied polymorphisms and cholelithiasis in this high prevalent population.

关键词： Apolipoprotein CYP7A1 Gallstones Mexicans Polymorphisms

Triboelectric nanogenerator based on electrodeposited Ag octahedral nano-assemblies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2023年第8期83卷 478-495,I0012页

作者： M.Edith navarro-segura Margarita sanchez-Dominguez Ana Arizmendi-Morquecho J.Alvarez-Quintana Group of Colloidal and Interfacial Chemistry Applied to Nanomaterials and Nanoformulations Centro de Investigacion en Materiales Avanzados S.C Unidad MonterreyAlianza Norte#202Autopista Monterrey-Aeropuerto Km.10.C.P.66628 ApodacaNuevo LeonMexico GENEs-Group of Embedded Nanomaterials for Energy scavenging Centro de Investigacion en Materiales Avanzados S.C.Unidad MonterreyAlianza Norte#202Autopista Monterrey-Aeropuerto Km.10.C.P.66628 ApodacaNuevo LeonMexico

The tremendous potential of triboelectric generators-TENGs for converting mechanical energy into electrical energy places them as one of the most promising energy harvesting technologies. In this work, the fabrication of enhanced performance TENGs using Ag octahedron nano-assemblies on ITO as electrodes significantly increases the electric charge collection of the induced tribocharges. Thereby, nanostructured electrical contacts coated with Ag macroscale nano-assemblies with octahedral features were obtained by the electrodeposition technique on flexible PET/ITO substrates. Consequently, the nanostructured triboelectric generator-TENG exhibited 65 times more maximum output power, and almost 10 times more open circuit output voltage than that of a TENG with non-nanostructured contacts passing from μW to m W capabilities, which was attributed to the increment of intrinsic interface states due to a higher effective contact area in the former. Likewise, output performances of TENGs also displayed an asymptotic behavior on the output voltage as the operating frequency of the mechanical oscillations increased, which is attributed to a decrement in the internal impedance of the device with frequency. Furthermore, it is shown that the resulting electrical output power can successfully drive low power consumption electronic devices. On that account, the present research establishes a promising platform which contributes in an original way to the development of the TENGs technology.

关键词： Triboelectric generator Nanostructured electrodeposited electrodes Ag octahedral nanoassemblies Electrode surface structure

A social media adoption strategy for cultural dissemination in municipalities with tourist potential:Lamas,Peru,as a case study

在线全文

学校读者我要写书评

暂无评论

Built Heritage 2024年第2期8卷 67-78页

作者： Pierre Vidaurre-Rojas seidy Janice Vela-Reátegui Lloy Pinedo Miguel Valles-Coral Jorge Raul navarro-Cabreraand Very Rengifo-Hidalgo Teresa del Pilar López-sánchez Joséseijas-Díaz Ángel Cárdenas-García Rosa Elena Cueto-Orbe ATEC Management Research Group Faculty of Economic SciencesUniversidad Nacional de San MartínJr.Maynas N°177TarapotoPerú Faculty of systems and Informatics Engineering Universidad Nacional de San MartínJr.Maynas N°177TarapotoPerú Tourism Development and International Business Research Group Faculty of EconomicAdministrative and Accounting SciencesUniversidad Nacional Autónoma de Alto AmazonasProlongación Libertad 1220-1228YurimaguasPerú Tourism Development and International Business Research Group Faculty of International Business and TourismUniversidad Nacional Autonoma de Alto AmazonasProlongación Libertad 1220-1228YurimaguasPerú

social media is commonly used by governments to disseminate information related to transparency and institutional promotion,but its potential for the dissemination of cultural resources is often *** research proposes a strategy for adopting social media to achieve cultural dissemination in the municipality of Lamas,Peru,which has tourism potential and has been awarded the“Best Tourism Villages”seal of the World Tourism ***,we propose a case study at a propositional exploratory *** start by determining the current state of dissemination of tangible and intangible resources,as well as the practical use of social media,through a survey of 20 *** results reveal that crafts are the most widely disseminated tangible resource in the municipality(according to 55%of officials),and intangible resources are occasionally disseminated(50%).We also find that Facebook is the only digital channel used to disseminate cultural *** this context,we formulate a strategy for adopting social media to improve cultural dissemination,which consists of six phases:(i)forming a work team,(ii)preparing a budget plan,(iii)strengthening capacities,(iv)taking inventory of cultural resources,(v)coordinating community interests and(vi)preparing a cultural dissemination *** findings can contribute to formulating public initiatives for the institutionalisation of social media in governments for the purposes of preserving,promoting and guaranteeing the accessibility of cultural heritage.

关键词： Cultural heritage Cultural preservation Cultural promotion Digital attraction Digital communication Government social networks Tourism development Visitors

Photodegradation and Removal of Diclofenac by the Green Alga Nannochloropsis oculata

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2021年第5期90卷 1519-1533页

作者： Danaé samara sánchez-sandoval Omar González-Ortega Mara Fernanda navarro-Martínez Juan Marcos Castro-Tapia Ramón Fernando García de la Cruz Ruth Elena soria-Guerra Facultad de Ciencias Químicas Universidad Autónoma de San Luis PotosíSan Luis Potosí78210México

The emerging contaminants(ECs)are organic compounds including *** products are consumed in large quantities,favoring their continuous entrance to the environment and affecting the health of living *** is a non-steroidal anti-inflammatory drug with analgesic properties of prolonged *** is the commonest postoperative analgesic,and it is highly consumed without *** recent years,the capability of microalgae to remove pharmaceuticals in water has been tested as a promising *** this work,the removal efficiency of diclofenac(16µg/mL)by the microalga Nannochloropsis oculata CCAP 186/7 was *** major nutrient concentrations in Bold’s Basal Medium were modified(nitrogen and carbon:50 and 100%of their original concentration)to know their effect in the removal of *** degradation by light was also *** maximum removal capacity of diclofenac in the medium was 68.8%.The percentage of diclofenac adsorbed on the cell wall was between 6 and 12.7%.Around 23.6%of diclofenac was degraded by light after 18 *** did not show growth inhibition due to the presence of *** results obtained point to the promissory application of *** as a bioremediation system for diclofenac removal.

关键词： Adsorption emerging contaminants microalgae pharmaceuticals phycoremediation photodegradation

Enzymes of Entomopathogenic Fungi, Advances and Insights

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Enzyme Research 2014年第2期2卷 65-76页

作者： Lluvia de Carolina sánchez-Pérez Juan Esteban Barranco-Florido silvia Rodríguez-navarro José Francisco Cervantes-Mayagoitia Miguel ángel Ramos-López Departamento de Producción Agrícola y Animal Universidad Autónoma Metropolitana México City México Departamento de sistemas Biológicos Universidad Autónoma Metropolitana México City México Facultad de Química Universidad Autónoma de Querétaro Querétaro México

Entomopathogenic fungi (EF) are recognized biological control agents of insects. Basically, the entomopathogenic fungi pathogen activity depends on the ability of its enzymatic equipment, consisting of lipases, proteases and chitinases, which are in charge of breaking down the insect’s integument. Lipases are the first enzymes synthesized by the entomopathogenic fungi. Recently, a cytochrome P450 subfamily, referred as CYP52XI and MrCYP52 has been identified in Beauveria bassiana and Metarhizium robertsii, respectively. These break down long-chain alkenes and fatty acids to become initial nutrients. subsequently, subtilisin type (Pr1) proteases sintetize;these enzymes are considered as virulence indicators and they are regulated by a signal transduction mechanism activated by the protein kinase A (PKA) mediated by AMPc. Through the employment of genetic engineering, it has been possible to increase virulence producing Pr1 recombinants with Androctonus australis neurotoxins or with chitinases, reducing the insect’s time of death. In the course of time, the Pr1 protease gene has presented evolutionary adaptations by gene duplication or horizontal transfer infecting different orders of insects. In the same way, the entomopathogenic fungi chitinases have presented a functional diversification. Currently, these have been phylogenetically classified into three subgroups, in accordance to the catalytic site domain and the chitin binding domain. The chitinolytic activity has increased through a directed evolution processes and genetic recombination with Bombyx mori chitinase. Recently, enzymes have been employed as control agents for insects and phytopathogenic fungi (disease originator) opening new potentialities in order to improve the entomopathogenic fungi use. solid state fermentation is a bioprocess that would produce at great scale enzymes and some other metabolites in grade of increasing the entomopathogenic fungi virulence, in the control of insects and potentially

关键词： Lipases Proteases Chitinases Host Evolution Biocontrol Agent