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Bivariate Analysis of Pollutants Monthly Maxima in Mexico City Using Extreme Value Distributions and Copula

Journal of Environmental Protection 2024年第7期15卷 796-826页

作者： Juan A. Vazquez-morales Eliane R. Rodrigues Hortensia J. Reyes-Cervantes Facultad de Ciencias Fsico-Matemticas Benemrita Universidad Autnoma de Puebla Puebla Mexico Instituto de Matemticas Universidad Nacional Autnoma de Mxico Mexico City Mexico

In the present work, we are interested in studying the joint distributions of pairs of the monthly maxima of the pollutants used by the environmental authorities in Mexico City to classify the air quality in the metropolitan area. In order to obtain the joint distributions a copula will be considered. Since we are analyzing the monthly maxima, the extreme value distributions of Weibull and Fréchet are taken into account. Using these two distributions as marginal distributions in the copula a Bayesian inference was made in order to estimate the parameters of both distributions and also the association parameters appearing in the copula model. The pollutants taken into account are ozone, nitrogen dioxide, sulphur dioxide, carbon monoxide, and particulate matter with diameters smaller than 10 and 2.5 microns obtained from the Mexico City monitoring network. The estimation was performed by taking samples of the parameters generated through a Markov chain Monte Carlo algorithm implemented using the software OpenBugs. Once the algorithm is implemented it is applied to the pairs of pollutants where one of the coordinates of the pair is ozone and the other varies on the set of the remaining pollutants. Depending on the pollutant and the region where they were collected, different results were obtained. Hence, in some cases we have that the best model is that where we have a Fréchet distribution as the marginal distribution for the measurements of both pollutants and in others the most suitable model is the one assuming a Fréchet for ozone and a Weibull for the other pollutant. Results show that, in the present case, the estimated association parameter is a good representation to the correlation parameters between the pair of pollutants analyzed. Additionally, it is a straightforward task to obtain these correlation parameters from the corresponding association parameters.

关键词： Copula Extreme Value Distribution Bayesian Inference Air Pollution Mexico City

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Interindividual Age-Independent Differences in Human CX43 Impact Ventricular Arrhythmic Risk

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Research 2024年第3期6卷 417-432页

作者： Laura García-Mendívil María Pérez-Zabalza Antoni Oliver-Gelabert JoséMaría Vallejo-Gil Javier Fañanás-Mastral Manuel Vázquez-Sancho Javier AndréBellido-morales Alexánder Sebastián Vaca-Núñez Carlos Ballester-Cuenca Emiliano Diez Laura Ordovás Esther Pueyo Biomedical Signal Interpretation and Computational Simulation group(BSICoS) Aragón Institute of Engineering ResearchUniversity of ZaragozaZaragoza 50018Spain BSICoS Instituto de Investigación Sanitaria Aragón(IISA)Zaragoza 50018Spain Centro Universitario de la Defensa(CUD) Zaragoza 50090Spain. Department of Cardiovascular Surgery University Hospital Miguel ServetZaragoza 50009Spain. Institute of Experimental Medicine and Biology of Cuyo(IMBECU) CONICETMendoza 5500Argentina. Fundación Agencia Aragonesa para la Investigación y el Desarrollo(ARAID) Zaragoza 50018Spain. Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine(CIBER-BBN)Zaragoza 50018Spain.

Connexin 43 (CX43) is one of the major components of gap junctions, the structures responsible for the intercellular communication and transmission of the electrical impulse in the left ventricle. There is limited information on the histological changes of CX43 with age and their effect on electrophysiology, especially in humans. Here, we analyzed left ventricular biopsies from living donors starting at midlife to characterize age-related CX43 remodeling. We assessed its quantity, degree of lateralization, and spatial heterogeneity together with fibrotic deposition. We observed no significant age-related remodeling of CX43. Only spatial heterogeneity increased slightly with age, and this increase was better explained by biological age than by chronological age. Importantly, we found that CX43 features varied considerably among individuals in our population with no relevant relationship to age or fibrosis content, in contrast to animal species. We used our experimental results to feed computational models of human ventricular electrophysiology and to assess the effects of interindividual differences in specific features of CX43 and fibrosis on conduction velocity, action potential duration, and arrhythmogenicity. We found that larger amounts of fibrosis were associated with the highest arrhythmic risk, with this risk being increased when fibrosis deposition was combined with a reduction in CX43 amount and/or with an increase in CX43 spatial heterogeneity. These mechanisms underlying high arrhythmic risk in some individuals were not associated with age in our study population. In conclusion, our data rule out CX43 remodeling as an age-related arrhythmic substrate in the population beyond midlife, but highlight its potential as a proarrhythmic factor at the individual level, especially when combined with increased fibrosis.

关键词： CX43 rhythm Independent

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Organ Abscission in Plants: With Special Emphasis on Bell Pepper

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1467-1484页

作者： Ramiro Reyes-Castro Héctor G.Núñez-Palenius Juan I.Valiente-Banuet María E.Sosa-morales Blanca E.Orosco-Alcalá Rafael Guzmán-Mendoza Graciela M.L.Ruiz-Aguilar Rogelio Costilla-Salazar Life Sciences Division Universidad de GuanajuatoIrapuato36500México School of Engineering and Sciences Tecnologico de MonterreyQuerétaro76130México

Bell pepper(Capsicum annuum L.),along with potato and tomato,is one of the three most cultivated vegetables in the *** pepper is worldwide accepted due to its characteristics of color,smell,ﬂavor,and *** pepper is also considered a nutritious food due to its vitamin and antioxidant *** Mexico,bell pepper production has a high value because it is grown for the international markets,particularly the United States of ***,the abscission ofﬂowers and fruits is a factor that limits the yield,hinders the planning of activities,and causes a variation in the prices of *** to the importance of this process,in this work we did a bibliometric analysis and literature review of scientiﬁc advances for the understanding of the abscission pro-cess in plants,and in particular for the bell ***,we introduce new perspectives that would help direct future research about organ abscission in ***,the lack of research that would further clarify abscis-sion process in the bell pepper plant is discussed.

关键词： Capsicum annuum abscission zone plant growth regulators environmental factors

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Evaluation of Human Impacts on Bartlett Pond Ecosystem, Laredo, Southern Texas, USA, through Empirical Modeling

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Journal of Environmental Protection 2024年第4期15卷 497-526页

作者： Maya P. Bhatt Amede Rubio Ganesh B. Malla Cristobal Lopez Virginia morales Erick Vazquez Cano David Marquez Orlando Berumen Alvarez Alfred Addo-Mensah Department of Biology and Chemistry Texas A&M International University Laredo USA Department of Mathematics Computer Geology and Physics University of Cincinnati-Clermont College Batavia USA

The trace elements chemistry of Bartlett Pond, a small shallow wetland pond in Laredo, Southern Texas, was sampled to evaluate the dynamics of trace elements impacts on water quality and ecosystems ecology of the pond. Two types of fish (bass and tilapia) were also sampled to see the trace element accumulation in different parts of their body. The concentrations of trace elements in water samples were found in the following order: Fe ≫Sb > Pb > As ≫Co > Tl > Cr > Cd within Bartlett Pond. Overall, the water quality of the pond is unacceptable for drinking and any other purposes as trace element concentrations (e.g. As, Cd, Co, Cr, Pb, Fe, Sb and Tl) are exceedingly higher (several fold) than the WHO and US EPA guidelines. Predictive and correlation analysis shows that most trace elements exhibit a strong positive correlation among them indicating the same anthropogenic sources and biogeochemical processes regulate these trace elements within the pond. Distributions of the trace elements in water exhibit different shapes mostly as positively skewed distribution for As, Cd, Co, Cr, and Tl, symmetrical distribution for Fe and almost symmetrical distribution for Pb and Sb. Concentrations of As, Co and Tl accumulated much higher in different parts of the Bass than Tilapia fish. The concentrations of As, Tl, Co, and Sb appeared significantly higher in different parts of the body of both Bass and Tilapia than the maximum SRM certified values. Accumulation of these contaminants in fish tissues pose increased health risks to humans who consume these contaminated fish although fishing is prohibited. Anthropogenic activities in the region primarily degrade the whole pond ecosystem ecology of the Bartlett Pond and waters of this pond to be not recommended for any use. These findings may be useful for the scientific community and concerned authorities to improve understanding about these precious natural resources and conservation of the ecosystem ecology.

关键词： Trace Elements Bartlett Pond Laredo Southern Texas Wetlands Ecosystem Ecology

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Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation:a systematic review and meta-analysis

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世界儿科杂志:英文版 2023年第8期19卷 727-740页

作者： Álvaro Lassaletta Javier S.morales Pedro L.Valenzuela Borja Esteso Lisa S.Kahalley Donald J.Mabbott Soumya Unnikrishnan Elena Panizo Felipe Calvo Radiation Oncology Department Clínica Universidad de NavarraCalle Marquesado de Santa Marta 128027 MadridSpain Pediatric Neuro-Oncology Unit Hospital Infantil Universitario Niño JesúsMadridSpain MOVE-IT Research Group Department of Physical EducationFaculty of Education SciencesUniversity of CadizCádizSpain Biomedical Research and Innovation Institute of Cádiz(INiBICA)Research Unit Puerta del Mar University HospitalUniversity of CádizCádizSpain Physical Activity and Health Research Group(PaHerg) Research Institute of the Hospital 12 de Octubre(‘imas12’)MadridSpain Systems Biology Department University of AlcaláMadridSpain Clinical Neuropsychology Unit Psychiatry and Clinical Psychology DepartmentHospital Infantil Universitario Niño JesúsMadridSpain Baylor College of Medicine HoustonTXUSA Texas Children’s Hospital HoustonTXUSA The Hospital for Sick Children TorontoONCanada The University of Toronto TorontoONCanada University of California School of Medicine San DiegoLa JollaCAUSA

Background Advances in cancer treatments,particularly the development of radiation therapy,have led to improvements in survival outcomes in children with brain ***,radiation therapy is associated with significant long-term neurocognitive *** present systematic review and meta-analysis aimed to compare the neurocognitive outcomes of children and adolescents with brain tumors treated with photon radiation(XRT)or proton therapy(PBRT).Methods A systematic search was conducted(PubMed,Embase,Cochrane,and Web of Science from inception until 02/01/2022)for studies comparing the neurocognitive outcomes of children and adolescents with brain tumors treated with XRT *** pooled mean differences(expressed as Z scores)were calculated using a random effects method for those endpoints analyzed by a minimum of three *** Totally 10 studies(n=630 patients,average age range:1–20 years)met the inclusion *** who had received PBRT achieved significantly higher scores(difference in Z scores ranging from 0.29–0.75,all P0.05 in main analyses or sensitivity analyses)were found for nonverbal memory,verbal working memory and working memory index,processing speed index,or focused *** Pediatric brain tumor patients who receive PBRT achieve significantly higher scores on most neurocognitive outcomes than those who receive *** studies with long-term follow-ups are needed to confirm these results.

关键词： Brain health Childhood cancer Intelligence quotient Radiotherapy

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让中国文学保持与世界接轨

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中国新闻发布（实务版） 2024年第4期 31-32页

作者：夏海明不详

我第一次到中国是2007年8月底。那时,我刚毕业不久,从来没有离开过家乡,更没有在国外生活的经验,选择去北京的某所大学读书可以说是一种探险,也是我一生中意义最大的经历之一。我大学读的是中西翻译和汉学研究专业,但那时我对中国文化... 详细信息

我第一次到中国是2007年8月底。那时,我刚毕业不久,从来没有离开过家乡,更没有在国外生活的经验,选择去北京的某所大学读书可以说是一种探险,也是我一生中意义最大的经历之一。我大学读的是中西翻译和汉学研究专业,但那时我对中国文化和中国国情的了解非常有限。当时决定到中国来,我的主要目标是进修汉语课程,实地提升我的中文水平,以及拓宽对中国各方面的了解。

关键词：汉学研究汉语课程中文水平读书中国国情

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Recent results from NA48/2

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Chinese Physics C 2010年第6期34卷 749-752页

作者： Cristina morales morales Institut für Physik Universitt Mainz

Recent results on radiative K^± decays from the NA48/2 experiment are reported. From the full NA48/2 data set, about a million K^±→π^±π^γ decays were reconstructed. Based on this sample, the first measurement of the interference between direct photon emission and inner bremsstrahlung in K^±→π^±π^γ decays was performed. Stringent limits on CP violation in this decay were also set. In addition, a precise measurement of the branching fraction of K^±→π^±γγ is presented. This measurement was based on a data sample of more than 1000 event candidates. Also the related decay K^±→π^±e^＋e^-γ has first been observed. Results of the measurement of the decay rate and the decay parameter 5 are summarized.

关键词： radiative K^± decays NA48/2 CP violation

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海风吹过的夏天墨西哥某住宅

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室内设计与装修 2024年第9期 24-31页

作者： [墨西哥]Estudio Carroll 麦子(编译) Cesar Belio(摄影) Victor morales(摄影) Richard Stow(摄影) Estudio Carroll

作为设计师和建筑师,在全球气温逐年上升的时代,通过项目节能减排,为地球做出贡献,变得越发重要。当有机会为一对渴望在墨西哥瓦哈卡海边拥有一片自己天地的夫妇建造一处住宅时,这种责任转变成了该项目设计理念的精神指引。

关键词：全球气温节能减排住宅设计理念建筑师墨西哥设计师

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Fulminant Hepatitis Associated with Chronic Consumption of 3,4-Methylenedioxy-Methamphetamine;Case Report

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Open Journal of Gastroenterology 2024年第5期14卷 161-166页

作者： Ulises Solis Gomez Gustavo Adolfo Hernández Valdez Juan Antonio Contreras Escamilla Ivan Alejandro Medina Jimenez Jorge morales Rojas Jocelyn Nataly Quintero Melendez Marco Antonio González Villar Department of Internal Medicine ISSSTE APP General Hospital of Tepic Tepic Nayarit Mexico

The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA), also called ecstasy, is a neurotoxin widely consumed among young people that has increased in recent years because it is a recreational drug, of which immediate effects are known such as a greater sensation of well-being, extroversion, increased sensory perception. However, its long-term effects have been described very little in the medical literature, including damage to the heart, central nervous system, kidney, etc. One of its little-known effects is hepatotoxicity, of which few cases are known associated with fulminant hepatitis, which is a rapidly deteriorating condition that is generally associated with a syndrome of multiple organ dysfunction and death. Therefore, it is very important to know this type of damage in the short and long term. The following case is of a 39-year-old man who came to our service due to jaundice syndrome and the only history of MDMA consumption, who as the days went by met the criteria for fulminant liver failure, with damage to multiple organs (organ dysfunction syndrome).

关键词： Fulminant Hepatitis Acute Liver Failure Methamphetamine Severe Acute Liver Failure in a User of Drugs of Abuse Hepatology

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On the Complexity of Expansive Measures

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Acta Mathematica Sinica,English Series 2015年第9期31卷 1501-1507页

作者： C.A.morales Instituto de Matem'atica Universidade Federal do Rio de Janeiro

We prove that the existence of positively expansive measures for continuous maps on compact metric spaces implies the existence of e 〉 0 and a sequence of （m, e）-separated sets whose cardinalities go to infinite as m →∞. We then prove that maps exhibiting such a constant e and the positively expansive maps share some properties.

关键词： Positively expansive measure complexity compact metric space

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