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Recent Advances in In-Memory Computing:Exploring Memristor and Memtransistor Arrays with 2D Materials

Nano-Micro Letters 2024年第7期16卷 1-30页

作者： Hangbo zhou Sifan Li Kah-Wee ang Yong-Wei Zhang Institute of High Performance Computing(IHPC) Agency for ScienceTechnology and Research(A*STAR)1 Fusionopolis Way#16-16 ConnexisSingapore 138632Republic of Singapore Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117583Republic of Singapore Institute of Materials Research and Engineering Agency for ScienceTechnology and Research(A*STAR)2 Fusionopolis WaySingapore 138634Republic of Singapore

The conventional computing architecture faces substantial chal-lenges,including high latency and energy consumption between memory and processing *** response,in-memory computing has emerged as a promising alternative architecture,enabling computing operations within memory arrays to overcome these *** devices have gained significant attention as key components for in-memory computing due to their high-density arrays,rapid response times,and ability to emulate biological *** these devices,two-dimensional(2D)material-based memristor and memtransistor arrays have emerged as particularly promising candidates for next-generation in-memory computing,thanks to their exceptional performance driven by the unique properties of 2D materials,such as layered structures,mechanical flexibility,and the capability to form *** review delves into the state-of-the-art research on 2D material-based memristive arrays,encompassing critical aspects such as material selection,device perfor-mance metrics,array structures,and potential ***,it provides a comprehensive overview of the current challenges and limitations associated with these arrays,along with potential *** primary objective of this review is to serve as a significant milestone in realizing next-generation in-memory computing utilizing 2D materials and bridge the gap from single-device characterization to array-level and system-level implementations of neuromorphic computing,leveraging the potential of 2D material-based memristive devices.

关键词： 2D materials Memristors Memtransistors Crossbar array In-memory computing

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Ce-modified USY zeolite catalysts for catalytic oxidation of chlorinated VOCs:Effect of the location of CeO2 and its synergistic effect with USY zeolite

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Journal of Rare Earths 2024年第11期42卷 2068-2077页

作者： Xiaolin Guo Zhiming Li ang zhou Yijun Shi Yong Wang Renxian zhou Institute of Catalysis Zhejiang University College of Materials and Chemistry China Jiliang University

The catalytic behavior of a catalyst for chlorine-containing volatile organic compounds（CVOCs） oxidation largely depends on the synergistic interaction between the oxidizing and acidic *** the present work,two catalysts with different distributions of CeO2on the inner and outer surfaces of 4.0Ce-USY-ex and 4.0Ce-USY-dp（USY zeolite） were prepared respectively by ion exchange and deposition methods,with a purpose of finding out how the location of the oxidation sites（CeO2） influence its synergistic effect with the acidic sites of *** results show that 4.0Ce-USY-ex is much more active for catalytic degradation of 1,2-dichloroethane（DCE）,while 4.0Ce-USY-dp catalyst exhibit higher catalytic degradation activity for other structured CVOCs(dichloromethane（DCM）,trichloroethylene（TCE）,chlorobenzene（CB）).CeO2in 4.0Ce-USY-ex catalyst mainly disperses in the pore channels of USY zeolite,and there are many strong acid centers on the surface,which is conducive to the dechlorination conversion of ***,CeO2in 4.0Ce-USY-dp catalyst is mainly distributed on the outer surface of USY and has strong oxidation ability,which contributes to the deep oxidation of ***,the presence of a large number of strong acid centers on the catalyst surface of 4.0Ce-USY-ex catalysts leads to severe accumulation of surface carbon species and significantly decreases its stability towards ***,a large number of active oxygen species on the surface of 4.0Ce-USY-dp and CeO2catalysts are beneficial to the deep oxidation of DCE,reducing the formation of surface carbon and thus improving the stability of the ***,the influence of the location of the oxidation sites on its synergistic effect with the acidic sites was established in the present work,which could provide some new ideas for the rational design of CVOCs degradation catalyst with appropriate distribution of active sites.

关键词： CeO2 CVOCs oxidation Location Rare earths Synergistic effect USY

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Mixed Alkali-zinc Effects on Thermo-mechanical Properties in Borosilicate Glasses

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1093-1099页

作者： XIAO Guanzhou TAO Yunhang zhou Hemin ZHENG Qingshuang QIAO ang TAO Haizheng State Key Laboratory of Silicate Materials for Architectures Wuhan University of TechnologyWuhan 430070China Wuhan University of Technology Advanced Engineering Technology Research Institute of Zhongshan City Zhongshan 528437China

A series of mixed alkali-zinc borosilicate glasses with various r values(r=molar ratio of[ZnO]/([R^(2)O]+[ZnO]))from 0.00 to 1.00 were fabricated to probe the mixed alkali-zinc effects on thermo-mechanical *** nonlinear evolution of glass transition temperature(T_(g))with the addition of ZnO is ascribed to the competition of two converse factors,i e,the T_(g)depression as one of the colligative properties for a solution,on the one hand,and the enhancement of T_(g)due to the higher field strength of zinc cations compared to that of alkali ***,the nonlinear evolution of elastic moduli and coefficients of thermal expansion with r is attributed to the variance of intermediate-range clusters,which is confirmed by infrared and Raman scattering *** findings are very helpful in tailoring the performance of borosilicate glasses.

关键词： glass transition temperature elastic moduli coefficient of thermal expansion borosilicate glass

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Myotis bat STING attenuates aging-related inflammation in female mice

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Zoological Research 2024年第5期45卷 961-971页

作者： Xi Wang Jing-Kun Jia Qi Wang Jing-Wen Gong ang Li Jia Su Peng zhou Wuhan Institute of Virology Chinese Academy of SciencesWuhanHubei 430071China Guangzhou National Laboratory Guangzhou International Bio IslandGuangzhouGuangdong 510005China University of Chinese Academy of Sciences Beijing 100000China State Key Laboratory of Respiratory Disease First Affiliated Hospital of Guangzhou Medical SchoolGuangzhouGuangdong 510005China

Bats,notable as the only flying mammals,serve as natural reservoir hosts for various highly pathogenic viruses in humans(e.g.,SARS-CoV and Ebola virus).Furthermore,bats exhibit an unparalleled longevity among mammals relative to their size,particularly the Myotis bats,which can live up to 40 ***,the mechanisms underlying these distinctive traits remain incompletely *** our prior research,we demonstrated that bats exhibit dampened STING-interferon activation,potentially conferring upon them the capacity to mitigate virus-or aging-induced *** substantiate this hypothesis,we established the first in vivo bat-mouse model for aging studies by integrating Myotis davidii bat STING(MdSTING)into the mouse *** monitored the genotypes of these mice and performed a longitudinal comparative transcriptomic analysis on MdSTING and wild-type mice over a 3-year aging *** transcriptomic analysis indicated a reduction in aging-related inflammation in female MdSTING mice,as evidenced by significantly lower levels of pro-inflammatory cytokines and chemokines,immunopathology,and neutrophil recruitment in aged female MdSTING mice compared to aged wild-type mice in *** results indicated that MdSTING knock-in attenuates the aging-related inflammatory response and may also improve the healthspan in mice in a sex-dependent *** the underlying mechanism awaits further study,this research has critical implications for bat longevity research,potentially contributing to our comprehension of healthy aging in humans.

关键词： Bat STING Longevity Aging-related inflammation Virus reservoir host

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Effects of longitudinal magnetic field on primary dendrite spacing and segregation of directionally solidified single crystal superalloy

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Progress in Natural Science:Materials International 2024年第1期34卷 26-36页

作者： Congjiang Zhang Yilin zhou Chen Shen Weili Ren Xiaotan Yuan Biao Ding Haibiao Lu Zuosheng Lei Yunbo Zhong ang Zhang State Key Laboratory of Advanced Special Steel College of Materials Science and Engineering Shanghai University National Engineering Research Center for Magnesium Alloys Natural Key Laboratory of Advanced Casting Technologies College of Materials Science and EngineeringChongqing University

The primary dendrite spacing(PDS) and segregation of directionally solidified single crystal(SC) superalloy under the longitudinal magnetic field(LMF) were investigated based on the analysis of the whole cross-sectional microstructure at different solidification distances. The results show that the PDS under the LMF remains basically unchanged at different solidification distances, and it is greater than that under no LMF. With the increase of magnetic field intensity, the PDS increases and the macrosegregation decreases. The increasing PDS and reducing segregation under the LMF can be attributed to the increase of solute boundary layer, which expands the non-equilibrium freezing temperature range and brings the effective partition coefficient closer to 1. The increase of the solute enrichment layer thickness could be caused by the downward secondary circulation generated by the thermoelectric magnetic convection(TEMC) near the interface, which drives the migration of solutes towards the interdendritic region. This work not only clarifies the mechanism of LMF controlling PDS and reducing segregation by TEMC, but also provides theoretical guidance for producing high-quality SC superalloys using magnetic fields.

关键词： Primary dendrite spacing Segregation Single crystal superalloy Directional solidification Magnetic field Thermoelectric magnetic convection

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Flexible polydimethylsiloxane pressure sensor with micro-pyramid structures and embedded silver nanowires:A novel application in urinary flow measurement

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Nanotechnology and Precision Engineering 2024年第3期7卷 1-12页

作者： Ben-Song Wang ang Gao Song-Wei Huang Qi-Hong Ning Cheng zhou Qi-Xiang Song Da-XiangCui School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Urology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240China

Flexible pressure sensors are lightweight and highly sensitive,making them suitable for use in small portable devices to achieve precise measurements of tiny *** article introduces a low-cost and easy-fabrication strategy for piezoresistive flexible pressure *** embedding silver nanowires into a polydimethylsiloxane layer with micro-pyramids on its surface,a flexible pressure sensor is created that can detect low pressure (17.3 Pa) with fast response (<20 ms) and high sensitivity (69.6 mA kPa-1).Furthermore,the pressure sensor exhibits a sensitive and stable response to a small amount of water flowing on its *** this basis,the flexible pressure sensor is innovatively combined with a micro-rotor to fabricate a novel urinary flow-rate meter (uroflowmeter),and results from a simulated human urination experiment show that the uroflowmeter accurately captured all the essential shape characteristics that were present in the pump-simulated urination *** ahead,this research provides a new reference for using flexible pressure sensors in urinary flow-rate monitoring.

关键词： Flexible pressure sensor Silver nanowires Portable device Uroﬂowmeter Healthcare

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Diabetes and high-glucose could upregulate the expression of receptor for activated C kinase 1 in retina

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World Journal of Diabetes 2024年第3期15卷 519-529页

作者： Jian Tan ang Xiao Lin Yang Yu-Lin Tao Yi Shao Qiong zhou Department of Ophthalmology The First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND Diabetic retinopathy(DR)is a major ocular complication of diabetes mellitus,leading to visual *** pigment epithelium(RPE)injury is a key component of the outer blood retinal barrier,and its damage is an important indicator of *** for activated C kinase 1(RACK1)activates protein kinase C-ε(PKC-ε)to promote the generation of reactive oxygen species(ROS)in RPE cells,leading to ***,we hypothesize that the activation of RACK1 under hypoxic/high-glucose conditions may promote RPE cell apoptosis by modulating PKC-ε/ROS,thereby disrupting the barrier effect of the outer blood retinal barrier and contributing to the progression of *** To investigate the role and associated underlying mechanisms of RACK1 in the development of early *** In this study,Sprague-Dawley rats and adult RPE cell line-19(ARPE-19)cells were used as in vivo and in vitro models,respectively,to explore the role of RACK1 in mediating PKC-εin early ***,the impact of RACK1 on apoptosis and barrier function of RPE cells was also investigated in the former *** Streptozotocin-induced diabetic rats showed increased apoptosis and upregulated expression of RACK1 and PKC-εproteins in RPE cells following a prolonged ***,ARPE-19 cells exposed to high glucose and hypoxia displayed elevated mRNA and protein levels of RACK1 and PKC-ε,accompanied by an increases in ROS production,apoptosis rate,and monolayer ***,silencing RACK1 significantly downregulated the expression of PKC-εand ROS,reduced cell apoptosis and permeability,and protected barrier *** RACK1 plays a significant role in the development of early DR and might serve as a potential therapeutic target for DR by regulating RPE apoptosis and barrier function.

关键词： Diabetic retinopathy Receptor for activated C kinase 1 Protein kinase C-ε Adult retinal pigment epithelium cell line-19

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Preliminary safety analysis for heavy water-moderated molten salt reactor

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Nuclear Science and Techniques 2024年第6期35卷 202-217页

作者： Gao-ang Wen Jian-Hui Wu Chun-Yan Zou Xiang-zhou Cai Jin-Gen Chen Man Bao College of Science University of Shanghai for Science and TechnologyShanghai 200093China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

The heavy water-moderated molten salt reactor(HWMSR)is a newly proposed reactor concept,in which heavy water is adopted as the moderator and molten salt dissolved with fissile and fertile elements is used as the *** arising from graphite in traditional molten salt reactors,including the positive temperature coefficient and management of highly radio-active spent graphite waste,can be addressed using the *** now,research on the HWMSR has been centered on the core design and nuclear fuel cycle to explore the viability of the HWMSR and its advantages in fuel ***,the core safety of the HWMSR has not been extensively ***,we evaluate typical accidents in a small modular HWMSR,including fuel salt inlet temperature overcooling and overheating accidents,fuel salt inlet flow rate decrease,heavy water inlet temperature overcooling accidents,and heavy water inlet mass flow rate decrease accidents,based on a neutronics and thermal-hydraulics coupled *** results demonstrated that the core maintained safety during the investigated accidents.

关键词： Heavy water-moderated molten salt reactor Neutronics and thermal-hydraulics coupling Transient analysis Accident analysis

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Fast-Response Fiber-Optic FPI Temperature Sensing System Based on Modulated Grating Y-Branch Tunable Laser

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Photonic Sensors 2024年第1期14卷 59-72页

作者： Yang CHEUNG Zhenguo JING Qiang LIU ang LI Yueying LIU Yihang GUO Sen ZHang Dapeng zhou Wei PENG School of Physics Dalian University of TechnologyDalian 116024China School of Optoelectronic Engineering and Instrumentation Science Dalian University of TechnologyDalian 116024China School of Computer and Electronic Information/School of Artificial Intelligence Nanjing Normal UniversityNanjing 210023China

In this paper,a cost-effective and miniaturized instrument is proposed,which is based on a tunable modulated grating Y-branch(MG-Y)laser for rapid temperature measurement using a Fabry-Perot interferometer(FPI)*** FPI sensor with a 1463-μm cavity length is a short segment of a capillary tube sandwiched by two sections of single-mode fibers(SMFs).This system has a broad tunable range(1527 nm-1567 nm)with a wavelength interval of 8 pm and a tuning rate of 100 *** sensing experiments are carried out to investigate the performance of the system by demodulating the absolute cavity length of the FPI sensor using a cross-correlation *** results show that the sensor can reach the response time as short as 94 ms with the sensitivity of 802 pm/*** from the homemade and integrated essential electrical circuits,the entire system has the small size,low cost,and practical application potential to be used in the harsh environment for rapid temperature measurement.

关键词： MG-Y laser interrogator rapid temperature measurement cross-correlation algorithm

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High-density lipoprotein regulates angiogenesis by affecting autophagy via miRNA-181a-5p

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Science China(Life Sciences) 2024年第2期67卷 286-300页

作者： Bi-ang Kang Hua-Ming Li Ya-Ting Chen Meng-Jie Deng Yan Li Yue-Ming Peng Jian-Jun Gao Zhi-Wei Mo Jia-Guo zhou Zhi-Jun Ou Jing-Song Ou Division of Cardiac Surgery Cardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases Guangzhou 510080China NHC key Laboratory of Assisted Circulation(Sun Yat-sen University) Guangzhou 510080China Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular Diseases Guangzhou 510080China Division of Vascular Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Department of Pharmacology Cardiac and Cerebral Vascular Research CenterZhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080China Division of Hypertension and Vascular Diseases Department of CardiologyCardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510080China Guangdong Provincial Key Laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080China

We previously demonstrated that normal high-density lipoprotein(nHDL)can promote angiogenesis,whereas HDL from patients with coronary artery disease(d HDL)is dysfunctional and impairs *** plays a critical role in angiogenesis,and HDL regulates ***,it is unclear whether n HDL and d HDL regulate angiogenesis by affecting *** cells(ECs)were treated with n HDL and d HDL with or without an autophagy ***,endothelial nitric oxide synthase(e NOS)expression,miRNA expression,nitric oxide(NO)production,superoxide anion(O2^(·-))generation,EC migration,and tube formation were evaluated.n HDL suppressed the expression of miR-181a-5p,which promotes autophagy and the expression of e NOS,resulting in NO production and the inhibition of O2^(·-)generation,and ultimately increasing in EC migration and tube formation.d HDL showed opposite effects compared to n HDL and ultimately inhibited EC migration and tube *** found that autophagy-related protein 5(ATG5)was a direct target of ***5 silencing or miR-181a-5p mimic inhibited n HDL-induced autophagy,e NOS expression,NO production,EC migration,tube formation,and enhanced O2^(·-)generation,whereas overexpression of ATG5 or miR-181a-5p inhibitor reversed the above effects of d ***5 expression and angiogenesis were decreased in the ischemic lower limbs of hypercholesterolemic low-density lipoprotein receptor null(LDLr^(-/-))mice when compared to C57BL/6 ***5 overexpression improved angiogenesis in ischemic hypercholesterolemic LDLr^(-/-)*** together,nHDL was able to stimulate autophagy by suppressing miR-181a-5p,subsequently increasing e NOS expression,which generated NO and promoted *** contrast,d HDL inhibited angiogenesis,at least partially,by increasing miR-181a-5p expression,which decreased autophagy and e NOS expression,resulting in a decrease in NO production and an increase in O2^(·-)*** findings reveal a nov

关键词： high-density lipoprotein angiogenesis autophagy ATG5 miRNA endothelial nitric oxide synthase

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