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Clinical characteristics and in-hospital outcomes of patients receiving contemporary intensive cardiac care:retrospective study from a large centre in China

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Journal of Geriatric Cardiology 2021年第2期18卷 94-103页

作者： Fei CHEN Yi-ming LI Qi liu Bao-Tao HUANG Fang-Yang HUANG Yong PENG Mao CHEN Department of Cardiology West China HospitalSichuan UniversityChengduChina West China School of Medicine Sichuan UniversityChengduChina

BACKGROUND Few studies from developed countries have quantitatively characterized the clinical characteristics and outcomes of patients receiving contemporary intensive cardiac *** sought to investigate these data in patients admitted to a Chinese intensive cardiac care unit(ICCU).METHODS We conducted a retrospective study using data from 2,337 consecutive admissions to the ICCU at a large centre in China from June 2016 to May *** were captured after systematic inspection of individual medical records regarding current demographics,primary diagnosis,comorbidities,illnesses severity,and in-hospital *** The mean age was 65.6±14.2 years,and females accounted for 32.0%of *** Charlson Comorbidity Index and Oxford Acute Severity of Illness Score were 2.4±1.8 and 22.5±10.4,*** top reason for admission was ST-segment elevation myocardial infarction(32.0%),and nonischaemic heart diseases accounted for 31.2%of all primary *** diseases were prevalent in the ICCU population,including chronic illnesses and acute noncardiovascular critical illnesses(ANCIs);in particular,21.7%of patients were marked by acute respiratory failure(14.6%),acute kidney injury(13.7%),sepsis(4.2%),or gastrointestinal bleeding(3.3%).The median length of stay in the ICCU and hospital were 1.1 days[interquartile range(IQR):0.8–2.6 days]and 6.3 days(IQR:3.8−10.9 days),*** overall incidence of in-hospital death or discharge against medical advice under extremely critical conditions was 7.6%(n=177).Multivariate logistic regression analysis showed that the complexity of chronic illnesses and incident ANCIs were strong independent determinants for in-hospital *** Remarkable patient diversity and breadth of critical illnesses were observed in a Chinese ICCU ***,noncardiovascular diseases were prevalent and associated with adverse *** of organization and staffing practices may be

关键词： patients admitted centre

High-throughput sequencing analysis of differentially expressed mi RNAs and target genes in ischemia/reperfusion injury and apelin-13 neuroprotection

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Neural Regeneration Research 2018年第2期13卷 265-271页

作者： Chun-mei Wang Xue-lu Yang ming-hui liu Bao-hua Cheng Jing Chen Bo Bai Neurobiology Institute Jining Medical University

miRNAs regulate a variety of biological processes through pairing-based regulation of gene expression at the 3＇ end of the noncoding region of the target miRNA, miRNAs were found to be abnormally expressed in ischemia/reperfusion injury models. High-throughput sequencing is a recently developed method for sequencing miRNAs and has been widely used in the analysis of miRNAs. In this study, ischemia/reperfusion injury models were intracerebroventricularly injected with 50 pg/kg apelin-13. High-throughput sequencing showed that 357 known miRNAs were differentially expressed among rat models, among which 78 changed to 〉 2-fold or 〈 0.5-fold. Quantita- tive real-time polymerase chain reaction was selected to confirm the expression levels of four miRNAs that were differentially expressed, the results of which were consistent with the results of high-throughput sequencing. Gene Ontology analysis revealed that the predicted targets of the different miRNAs are particularly associated with cellular process, metabolic process, single-organism process, cell, and binding. Kyoto Encyclopedia of Gene and Genome analysis showed that the target genes are involved in metabolic pathways, mitogen-ac- tivated protein kinase signaling pathway, calcium signaling pathway, and nuclear factor-KB signaling pathway. Our findings suggest that differentially expressed miRNAs and their target genes play an important role in ischemia/reperfusion injury and neuroprotection by apelin-13.

关键词： nerve regeneration RNA sequencing microRNA apelin ischemia/reperfusion injury neuroprotection neuropeptide high-throughput sequencing neural regeneration

PREPARATION OF MDPE-g-MAH COPOLYMERS AND THEIR EFFECT ON PROPERTIES OF MDPE/CaCO_3 SYSTEMS

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Chinese Journal of Polymer Science 2013年第9期31卷 1271-1275页

作者： Guo-dong Zhao Xiao-bo liu Guang-nan Qiu Jian-ming Xu Shi-ping Xie Xian-feng liu Jian-song Yang Lan-hang Xu Changyuan Electronics Co. Ltd. Changyuan Group Co. Ltd.

MDPE-g-MAH copolymers were prepared with MDPE （medium density polyethylene） and MAH （maleic anhydride） under different irradiation doses of high-energy electron accelerator, and FTIR spectra confirmed their structure. The effect of the different contents of MDPE-g-MAH copolymers on properties of MDPE/CaCO3 system is studied intensively. By adding 4 Phr （parts per hundred of resin） MDPE-g-MAH in MDPE/CaCO3 system under irradiation dose of 0.7 MGy, the tensile strength increases from 16.3 MPa to 19.9 MPa, and elongation at break increases from 437% to 518%. SEM images show the domain size of CaCO3 in MDPE-g-MAH systems becomes small. Definitely, MDPE-g-MAH copolymer could improve the compatibility of MDPE/CaCO3 system effectively.

关键词： MDPE-g-MAH copolymer MDPE CaCO3, Irradiation modification Compatibility.

Microstructure and magnetic performance of Nd–Y–Ce–Fe–B sintered magnets after annealing

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Rare Metals 2022年第3期41卷 859-864页

作者： Xiao-Lian liu Xiao-Wei Wu Jia-Ying Jin Yong-ming Tao Xin-Hua Wang Mi Yan Key Laboratory of Novel Materials for Sensor of Zhejiang Province College of Materials and Environmental EngineeringHangzhou Dianzi University310018 HangzhouChina School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China State Key Laboratory of Silicon Materials Zhejiang UniversityHangzhou 310027China Key Laboratory of Novel Materials for Information Technology of Zhejiang Province Zhejiang UniversityHangzhou 310027China

Annealing has been widely recognized as a crucial approach to modify the microstructure and enhance the coercivity of Nd–Fe–B magnets. However, in the context of Nd–Y–Ce–Fe–B magnets with multiple rare earths(REs) exhibiting different diffusion behaviors, annealing effects on the magnetic properties become more complicated and remain unknown.

关键词： Microstructure microstructure magnets

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芳纶纤维的发展现状及应用

纺织科学与工程学报 2024年第1期41卷 86-94页

作者：张玮刘姝瑞张明宇谭艳君西安工程大学陕西西安710048 陕西省功能材料染整创新工程研究中心陕西西安710048 广东绿纺新材料有限公司广东江门529000

总结了芳纶纤维的性能、改性研究、染色印花性能研究发展现状,以及芳纶纤维在金属化、体育运动、柔性防刺防弹材料、航空航天材料等的应用及研究情况。

关键词：芳纶纤维对位芳纶间位芳纶发展现状

Remove cooking fume using catalytic combustion over Pt/La-Al_2O_3

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Journal of Environmental Sciences 2007年第6期19卷 644-646页

作者： WANG Jian-li ZHONG Jun-bo GONG Mao-chu liu Zhi-min ZHAO ming CHEN Yao-qiang College of Chemistry Sichuan University Chengdu 610064 Sichuan ChinaI

Five monolithic catalysts with low noble metal content were prepared by irnmerge method （Pt/γ=Al2O3, Pt/La-Al2O3, Pt/YSZ-AI203, Pt＋Pd/La-Al2O3 and Pd/La-Al2O3） and their activity measurements were carried out in a conventional fixed-bed flow reactor. The results show that La-Al2O3 can promote activity of the prepared catalysts and can decrease the complete conversion temperature of cooking fume. The Pt/La-Al2O3 catalyst has the highest activity and can be applied in wide range of gas hourly space velocity （GHSV）. Some characterizations （XRD, TPR） were carried out with the objective to explain differences in catalytic behaviors. The prepared catalyst showed a great potential for application.

关键词： cooking fume monolithic catalyst remove catalytic combustion

The presence of intraductal carcinoma of the prostate is closely associated with poor prognosis:a systematic review and meta-analysis

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Asian Journal of Andrology 2021年第1期23卷 103-108页

作者： Yu-Cong Zhang Guo-Liang Sun De-Lin Ma Chao Wei Hao-Jie Shang Zhuo liu Rui Li Tao Wang Shao-Gang Wang Ji-Hong liu Xia-ming liu Department of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 43(X)30China Department of Geriatric Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Endocrine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

We aimed to confirm the predictive ability of the presence of intraductal carcinoma of the prostate(IDC-P)for prognosis and the associations between IDC-P and clinicopathological *** were identified in PubMed,Cochrane Library,EMBASE,Web of Science,and SCOPUS up to December 1,*** ratios(HRs)for survival data and odds ratios for clinicopathological data with 95%confidence intervals(CIs)were *** was evaluated by the I2 value,and quality was assessed by the Newcastle-Ottawa Scale criteria.A total of 4179 patients from 13 studies were *** results showed that IDC-P presence was significantly associated with poor progression-free survival(PFS;HR=2.31;95%Cl:1.96-2.73),cancer-specific survival(HR=1.89;95%Cl:1.28-2.77),and overall survival(HR=2.14;95%Cl:1.53-3.01).In the subgroup analysis,IDC-P presence was significantly associated with poor PFS in prostate cancer treated by radical prostatectomy(HR=2.48;95%Cl:2.05-3.00)and treated by radiotherapy(HR=2.83;95%Cl:1.65-4.85).Regarding clinicopathological characteristics,patients with IDC-P presence had significantly higher tumor clinical stages,Gleason scores,probabilities of lymph node invasion,positive surgical margins,and positive extraprostatic *** meta-analysis indicates that the presence of IDC-P is closely associated with poor prognosis and adverse clinicopathological *** data support the value and clinical utility of the routine detection of IDC-P by pathological *** conclusions need further validation,and prospective studies are needed to find better treatment modalities other than traditional first-line therapy for patients with IDC-P.

关键词： clinicopathological intraductal carcinoma of the prostate meta-analysis prognostic prostate cancer

Quantitative trait loci analysis for root traits in synthetic hexaploid wheat under drought stress conditions

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Journal of Integrative Agriculture 2020年第8期19卷 1947-1960页

作者： liu Rui-xuan WU Fang-kun YI Xin LIN Yu WANG Zhi-qiang liu Shi-hang DENG Mei MA Jian WEI Yu-ming ZHENG You-liang liu Ya-xi Triticeae Research Institute Sichuan Agricultural UniversityChengdu 611130P.R.China College of Environmental Sciences Sichuan Agricultural UniversityChengdu 611130P.R.China

Synthetic hexaploid wheat(SHW),possesses numerous genes for drought that can help breeding for drought-tolerant wheat *** evaluated 10 root traits at seedling stage in 111 F9 recombinant inbred lines derived from a F2 population of a SHW line(SHW-L1)and a common wheat line,under normal(NC)and polyethylene glycol-simulated drought stress conditions(DC).We mapped quantitative trait loci(QTLs)for root traits using an enriched high-density genetic map containing 120370 single nucleotide polymorphisms(SNPs),733 diversity arrays technology markers(DArT)and 119 simple sequence repeats(SSRs).With four replicates per treatment,we identified 19 QTLs for root traits under NC and DC,and 12 of them could be consistently detected with three or four *** novel QTLs for root fresh weight and root diameter under NC explained 9 and 15.7%of the phenotypic variation respectively,and six novel QTLs for root fresh weight,the ratio of root water loss,total root surface area,number of root tips,and number of root forks under DC explained 8.5–14%of the phenotypic *** seven of eight novel QTLs could be consistently detected with more than three *** provide essential information for fine-mapping QTLs related to drought tolerance that will facilitate breeding drought-tolerant wheat cultivars.

关键词： synthetic hexaploid wheat quantitative trait loci drought stress root traits

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不同流变剂对某矿全尾砂膏体充填性能的影响

矿业研究与开发 2024年第6期44卷 135-141页

作者：李广波盛宇航刘杰杨柳山东黄金矿业股份有限公司山东济南250100 山东黄金矿业科技有限公司充填工程实验室分公司山东莱州市261441

为了保证某矿全尾砂膏体充填料浆的安全高效输送,采用定性和定量分析方法分析了不同流变剂类型及掺量对于料浆流变特性和充填体强度的影响规律。结果表明:添加3种流变剂后,膏体充填料浆的流变特性得到明显改善,且掺量越多,流变参数整体... 详细信息

为了保证某矿全尾砂膏体充填料浆的安全高效输送,采用定性和定量分析方法分析了不同流变剂类型及掺量对于料浆流变特性和充填体强度的影响规律。结果表明:添加3种流变剂后,膏体充填料浆的流变特性得到明显改善,且掺量越多,流变参数整体降幅越大,但掺量过多会使料浆产生离析沉降现象。添加流变剂后,对于充填体1 d强度影响较大,但对于3 d、7 d、14 d、28 d强度几乎无影响。最佳流变剂选型为YSKJ01,掺量为0.4%时,全尾砂膏体充填性能达到最优。从微观角度阐述了流变剂对于改善全尾砂胶结充填料浆流变特性的作用机理,为该矿全尾砂膏体充填配比设计提供参考。

关键词：充填料浆流变剂流变特性充填体强度